Leticia Castillo, MD

Research output

Research output per year 1993 1993 1994 1995 1996 2009 2010 2011 2018

• 50 Article
• 3 Chapter
• 3 Letter
• 3 Review article
• 3 More
  • 2 Editorial
  • 1 Comment/debate

Research output per year

Research output per year

Search results

• 2018

  Secondary hemophagocytic lymphohistiocytosis, macrophage activation syndrome, and hyperferritinemic sepsis-induced multiple-organ dysfunction syndrome in the pediatric ICU

  Carcillo, J. A., Shakoory, B. & Castillo, L., Dec 10 2018, Pediatric Critical Care: Current Controversies. Springer International Publishing, p. 245-255 11 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  3 Scopus citations
• 2017

  A multifaceted approach to reduction of catheter-associated urinary tract infections in the intensive care unit with an emphasis on stewardship of culturing

  Mullin, K. M., Kovacs, C. S., Fatica, C., Einloth, C., Neuner, E. A., Guzman, J. A., Kaiser, E., Menon, V., Castillo, L., Popovich, M. J., Manno, E. M., Gordon, S. M. & Fraser, T. G., Feb 1 2017, In: Infection control and hospital epidemiology. 38, 2, p. 186-188 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Catheter-Related Infections 100%
  • Urinary Tract Infections 74%
  • Intensive Care Units 65%
  • Critical Care 25%
  • Infectious Disease Medicine 16%
  46 Scopus citations

• Insulin therapy for glycaemic control in critically ill children

  Lyons, J., Foster, B., Castillo, L. & Lyons, B. E., Feb 14 2017, In: Cochrane Database of Systematic Reviews. 2017, 2, CD009983.

  Research output: Contribution to journal › Article › peer-review

  • Critical Illness 100%
  • Critical Care 94%
  • Insulin 73%
  • Length of Stay 61%
  • Pediatrics 51%
• 2012

  Arginine, citrulline, and nitric oxide

  Luiking, Y. C., Castillo, L. & Deutz, N. E. P., Dec 22 2012, Modern Nutrition in Health and Disease: Eleventh Edition. Wolters Kluwer Health Adis (ESP), p. 477-486 10 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  2 Scopus citations

• Impact of resident duty hour limits on safety in the intensive care unit: A national survey of pediatric and neonatal intensivists

  Typpo, K. V., Tcharmtchi, M. H., Thomas, E. J., Kelly, P. A., Castillo, L. D. & Singh, H., Sep 2012, In: Pediatric Critical Care Medicine. 13, 5, p. 578-582 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Intensive Care Units 100%
  • Safety Management 90%
  • Pediatrics 77%
  • Physicians 76%
  • Formal Social Control 72%
  19 Scopus citations
• 2011

  Albumin synthesis rates in post-surgical infants and septic adolescents; influence of amino acids, energy, and insulin

  Verbruggen, S. C., Schierbeek, H., Coss-Bu, J., Joosten, K. F. M., Castillo, L. & van Goudoever, J. B., Aug 2011, In: Clinical Nutrition. 30, 4, p. 469-477 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Albumins 100%
  • Amino Acids 81%
  • Insulin 79%
  • Glucose 55%
  • Critical Illness 54%
  29 Scopus citations

• Current recommended parenteral protein intakes do not support protein synthesis in critically ill septic, insulin-resistant adolescents with tight glucose control

  Verbruggen, S. C. A. T., Coss-Bu, J., Wu, M., Schierbeek, H., Joosten, K. F. M., Dhar, A., Van Goudoever, J. B. & Castillo, L., Nov 2011, In: Critical care medicine. 39, 11, p. 2518-2525 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Critical Illness 100%
  • Amino Acids 75%
  • Insulin 73%
  • Glucose 67%
  • Proteins 39%
  44 Scopus citations

• Enteral arginase II provides ornithine for citrulline synthesis

  Marini, J. C., Keller, B., Didelija, I. C., Castillo, L. & Lee, B., Jan 2011, In: American Journal of Physiology - Endocrinology and Metabolism. 300, 1, p. E188-E194

  Research output: Contribution to journal › Article › peer-review

  • Ornithine 100%
  • Arginase 99%
  • Citrulline 98%
  • Small Intestine 69%
  • Arginine 43%
  16 Scopus citations

• Insulin resistance in critical illness

  Dhar, A. & Castillo, L., Jun 1 2011, In: Current Opinion in Pediatrics. 23, 3, p. 269-274 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Critical Illness 100%
  • Insulin Resistance 87%
  • Pathogen-Associated Molecular Pattern Molecules 72%
  • Inflammation 63%
  • Immunity 43%
  33 Scopus citations

• The Accreditation Council for Graduate Medical Education proposed work hour regulations

  Goodman, D. M., Winkler, M. K., Fiser, R. T., Abd-Allah, S., Mathur, M., Rivero, N., Weiss, I. K., Peterson, B., Cornfield, D. N., Mink, R., Nozik Grayck, E., McCabe, M. E., Schuette, J., Nares, M. A., Totapally, B., Petrillo-Albarano, T., Wolfson, R. K., Moreland, J. G., Potter, K. E., Fackler, J., & 34 othersGarber, N., Burns, J. P., Shanley, T. P., Lieh-Lai, M. W., Steiner, M., Tieves, K. S., Goldsmith, M., Asuncion, A., Ross, S. L. P., Howell, J. D., Biagas, K., Ognibene, K., Joshi, P., Rubenstein, J. S., Kocis, K. C., Cheifetz, I. M., Turner, D. A., Doughty, L., Hall, M. W., Mason, K., Penfil, S., Morrison, W., Hoehn, K. S., Watson, R. S., Garcia, R. L., Storgion, S. A., Fleming, G. M., Castillo, L., Tcharmtchi, M. H., Taylor, R. P., Ul Haque, I., Crain, N., Baden, H. P. & Lee, K. J., Jan 2011, In: Pediatric Critical Care Medicine. 12, 1, p. 120-121 2 p.

  Research output: Contribution to journal › Letter › peer-review
• 2010

  Arginine utilization for citrulline synthesis in arginase II knockout mice

  Marini, J. C., Didelija, I. C., Castillo, L. & Lee, B., Dec 1 2010, In: EAAP Scientific Series. 127, 1, p. 135-136 2 p.

  Research output: Contribution to journal › Article › peer-review

• Associations of four circulating chemokines with multiple atherosclerosis phenotypes in a large population-based sample: Results from the Dallas heart study

  Castillo, L., Rohatgi, A., Ayers, C. R., Owens, A. W., Das, S. R., Khera, A., Mcguire, D. K. & De Lemos, J. A., May 1 2010, In: Journal of Interferon and Cytokine Research. 30, 5, p. 339-347 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Chemokines 100%
  • Coronary Vessels 87%
  • Atherosclerosis 86%
  • Calcium 72%
  • Heart 69%
  31 Scopus citations

• Glutamine: Precursor or nitrogen donor for citrulline synthesis?

  Marini, J. C., Didelija, I. C., Castillo, L. & Lee, B., Jul 2010, In: American Journal of Physiology - Endocrinology and Metabolism. 299, 1, p. E69-E79

  Research output: Contribution to journal › Article › peer-review

  • Citrulline 100%
  • Glutamine 81%
  • Nitrogen 75%
  • Carbon 48%
  • ammonium acetate 16%
  49 Scopus citations

• Glutamine: Precursor or nitrogen donor for the synthesis of citrulline?

  Marini, J. C., Didelija, I. C., Castillo, L. & Lee, B., Dec 1 2010, In: EAAP Scientific Series. 127, 1, p. 123-124 2 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Parenteral amino acid intakes in critically Ill children: A matter of convenience

  Verbruggen, S., Sy, J., Arrivillaga, A., Joosten, K., Van Goudoever, J. & Castillo, L., May 2010, In: Journal of Parenteral and Enteral Nutrition. 34, 3, p. 329-340 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Critical Illness 100%
  • Amino Acids 75%
  • Child 46%
  • Muscle Proteins 25%
  • Human Milk 23%
  15 Scopus citations

• Plasma arginine and ornithine are the main citrulline precursors in mice infused with arginine-free diets

  Marini, J. C., Didelija, I. C., Castillo, L. & Lee, B., Aug 2010, In: Journal of Nutrition. 140, 8, p. 1432-1437 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ornithine 100%
  • Citrulline 98%
  • Arginine 70%
  • Diet 52%
  • Proline 13%
  18 Scopus citations

• Precursors for the synthesis of citrulline in mice fed arginine free diets

  Marini, J. C., Didelija, I. C., Castillo, L. & Lee, B., Dec 1 2010, In: EAAP Scientific Series. 127, 1, p. 133-134 2 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations
• 2009

  Arginine, citrulline and nitric oxide metabolism in sepsis

  Kao, C. C., Bandi, V., Guntupalli, K. K., Wu, M., Castillo, L. & Jahoor, F., 2009, In: Clinical Science. 117, 1, p. 23-30 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Citrulline 100%
  • Arginine 71%
  • Nitric Oxide 62%
  • Sepsis 62%
  • N,N-dimethylarginine 26%
  99 Scopus citations

• Continuous renal replacement therapy amino acid, trace metal and folate clearance in critically ill children

  Zappitelli, M., Juarez, M., Castillo, L., Coss-Bu, J. & Goldstein, S. L., Apr 2009, In: Intensive care medicine. 35, 4, p. 698-706 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Continuous Renal Replacement Therapy 100%
  • Folic Acid 75%
  • Critical Illness 70%
  • Metals 65%
  • Amino Acids 53%
  65 Scopus citations

• Ontogeny of methionine utilization and splanchnic uptake in critically ill children

  Verbruggen, S., Sy, J., Gordon, W. E., Hsu, J., Wu, M., Chacko, S., Zurakowski, D., Burrin, D. & Castillo, L., Nov 2009, In: American Journal of Physiology - Endocrinology and Metabolism. 297, 5, p. E1046-E1055

  Research output: Contribution to journal › Article › peer-review

  • Viscera 100%
  • Methionine 93%
  • Critical Illness 83%
  • Child 39%
  • Homocysteine 14%
  5 Scopus citations

• Recognizing, understanding, and treating critical community acquired methicillin-resistant Staphylococcus aureus infection in children

  Carcillo, J. A., Castillo, L., Thomas, J. & Kissoon, N., May 1 2009, In: Pediatric Critical Care Medicine. 10, 3, p. 405-407 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  3 Scopus citations

• Secondary hemophagocytic lymphohistiocytosis and severe sepsis/systemic inflammatory response syndrome/multiorgan dysfunction syndrome/macrophage activation syndrome share common intermediate phenotypes on a spectrum of inflammation

  Castillo, L. & Carcillo, J., May 1 2009, In: Pediatric Critical Care Medicine. 10, 3, p. 387-392 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Macrophage Activation Syndrome 100%
  • Hemophagocytic Lymphohistiocytosis 82%
  • Systemic Inflammatory Response Syndrome 78%
  • Sepsis 50%
  • Phenotype 37%
  210 Scopus citations
• 2008

  Adaptation to a long term (4 weeks) arginine- and precursor (glutamate, proline and aspartate)-free diet

  Tharakan, J. F., Yu, Y. M., Zurakowski, D., Roth, R. M., Young, V. R. & Castillo, L., Aug 2008, In: Clinical Nutrition. 27, 4, p. 513-522 10 p.

  Research output: Contribution to journal › Article › peer-review

  • arginine glutamate 100%
  • arginine aspartate 98%
  • Proline 62%
  • Arginine 54%
  • Diet 40%
  17 Scopus citations

• Bicarbonate kinetics and predicted energy expenditure in critically ill children

  Sy, J., Gourishankar, A., Gordon, W. E., Griffin, D., Zurakowski, D., Roth, R. M., Coss-Bu, J., Jefferson, L., Heird, W. & Castillo, L., Aug 1 2008, In: American Journal of Clinical Nutrition. 88, 2, p. 340-347 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bicarbonates 100%
  • Critical Illness 85%
  • Energy Metabolism 82%
  • Carbon Dioxide 80%
  • Kinetics 66%
  19 Scopus citations

• High elevated ferritin levels and the diagnosis of HLH/sepsis/SIRS/MODS/MAS

  Castillo, L., Nov 1 2008, In: Pediatric Blood and Cancer. 51, 5, 1 p.

  Research output: Contribution to journal › Letter › peer-review
  12 Scopus citations
• 2007

  Insulin therapy in the pediatric intensive care unit

  Verbruggen, S. C. A. T., Joosten, K. F. M., Castillo, L. & van Goudoever, J. B., Dec 2007, In: Clinical Nutrition. 26, 6, p. 677-690 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Pediatric Intensive Care Units 100%
  • Insulin 56%
  • Hyperglycemia 53%
  • Critical Illness 43%
  • Child 25%
  36 Scopus citations

• Interaction between murine spf-ash mutation and genetic background yields different metabolic phenotypes

  Marini, J. C., Erez, A., Castillo, L. & Lee, B., Dec 2007, In: American Journal of Physiology - Endocrinology and Metabolism. 293, 6, p. E1764-E1771

  Research output: Contribution to journal › Article › peer-review

  • Genetic Background 100%
  • Arginine 71%
  • Hyperammonemia 63%
  • Phenotype 56%
  • Mutation 52%
  15 Scopus citations
• 2005

  Hyperglycemia, asymmetric dimethylarginine, and patient survival: Dysregulation of complex networks and the metabolic basis of disease

  Castillo, L. & Al-Khadra, E., Mar 1 2005, In: Critical Care Medicine. 33, 3, p. 674-676 3 p.

  Research output: Contribution to journal › Editorial › peer-review

• Nutrition in the Critically Ill Child

  Mehta, N. & Castillo, L., Jan 1 2005, Pediatric Critical Care, Third Edition. Elsevier, p. 1068-1084 17 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  1 Scopus citations
• 2003

  Arginine and nitric oxide metabolism in critically ill septic pediatric patients

  Argaman, Z., Young, V. R., Noviski, N., Castillo-Rosas, L., Lu, X. M., Zurakowski, D., Cooper, M., Davison, C., Tharakan, J. F., Ajami, A. & Castillo, L., Feb 1 2003, In: Critical care medicine. 31, 2, p. 591-597 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Critical Illness 100%
  • Arginine 99%
  • Nitric Oxide 87%
  • Pediatrics 69%
  • Citrulline 26%
  107 Scopus citations
• 2002

  L-arginine-nitric oxide pathway in endstage reneal disease: Authors' reply

  Owen, W., Young, V. R., Ajami, A. & Castillo, L., 2002, In: American Journal of Kidney Diseases. 39, 1, p. 198-202 5 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Plasma L-5-oxoproline kinetics and whole blood glutathione synthesis rates in severely burned adult humans

  Yu, Y. M., Ryan, C. M., Fei, Z. W., Lu, X. M., Castillo, L., Schultz, J. T., Tompkins, R. G. & Young, V. R., 2002, In: American Journal of Physiology - Endocrinology and Metabolism. 282, 2 45-2, p. E247-E258

  Research output: Contribution to journal › Article › peer-review

  • Pyrrolidonecarboxylic Acid 100%
  • Glutathione 56%
  • Kinetics 45%
  • Glycine 31%
  • Leucine 16%
  46 Scopus citations
• 2001

  Arginine and ornithine kinetics in severely burned patients: Increased rate of arginine disposal

  Yu, Y. M., Ryan, C. M., Castillo, L., Lu, X. M., Beaumier, L., Tompkins, R. G. & Young, V. R., Mar 2001, In: American Journal of Physiology - Endocrinology and Metabolism. 280, 3 43-3, p. E509-E517

  Research output: Contribution to journal › Article › peer-review

  • Ornithine 100%
  • Arginine 70%
  • Kinetics 55%
  • Total Parenteral Nutrition 22%
  • Proline 20%
  91 Scopus citations

• Cysteine metabolism and whole blood glutathione synthesis in septic pediatric patients

  Lyons, J., Rauh-Pfeiffer, A., Ming-Yu, Y., Lu, X. M., Zurakowski, D., Curley, M., Collier, S., Duggan, C., Nurko, S., Thompson, J., Ajami, A., Borgonha, S., Young, V. R. & Castillo, L., 2001, In: Critical care medicine. 29, 4, p. 870-877 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Cysteine 100%
  • Glutathione 95%
  • Pediatrics 68%
  • Nutritional Support 27%
  • Critical Illness 21%
  115 Scopus citations
• 2000

  Arginine, citrulline, and nitric oxide metabolism in end-stage renal disease patients

  Lau, T., Owen, W., Yu, Y. M., Noviski, N., Lyons, J., Zurakowski, D., Tsay, R., Ajami, A., Young, V. R. & Castillo, L., May 2000, In: Journal of Clinical Investigation. 105, 9, p. 1217-1225 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Citrulline 100%
  • Arginine 71%
  • Chronic Kidney Failure 68%
  • Nitric Oxide 62%
  • Renal Dialysis 22%
  107 Scopus citations

• Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet

  Lyons, J., Rauh-Pfeiffer, A., Yu, Y. M., Lu, X. M., Zurakowski, D., Tompkins, R. G., Ajami, A. M., Young, V. R. & Castillo, L., May 9 2000, In: Proceedings of the National Academy of Sciences of the United States of America. 97, 10, p. 5071-5076 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Sulfur Amino Acids 100%
  • Glutathione 60%
  • Cysteine 47%
  • Diet 45%
  • Amino Acids 23%
  137 Scopus citations
• 1998

  Human arginine metabolism during end stage renal disease

  Castillo, L., Law, T., Owen, W. & Young, V. R., Mar 20 1998, In: FASEB Journal. 12, 5

  Research output: Contribution to journal › Article › peer-review

  • Arginine 100%
  • Citrulline 95%
  • Chronic Kidney Failure 87%
  • Pharmacological Metabolism 77%
  • Renal Dialysis 72%

• Nutrition and shock in pediatric patients

  Curley, M. A. Q. & Castillo, L., 1998, In: New Horizons: Science and Practice of Acute Medicine. 6, 2, p. 212-225 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Shock 100%
  • Nutritional Requirements 77%
  • Pediatrics 73%
  • Critical Illness 70%
  • Nutritional Support 44%
  20 Scopus citations
• 1997

  Adaptation to a long term (4 WKS) arginine-precursor-free diet in adult humans

  Castillo, L., Bedri, S., Beaumier, L., Ajami, A. & Young, V. R., Dec 1 1997, In: FASEB Journal. 11, 3

  Research output: Contribution to journal › Article › peer-review

  • Arginine 100%
  • Diet 68%
  • Citrulline 20%
  • Leucine 14%
  • arginine glutamate 14%
  2 Scopus citations

• Estimation of arginine oxidation and de novo synthesis in healthy adult men, using L-[5-¹³C]arginine

  Beaumier, L., Bedri, S., Castillo, L., Ajami, A. M. & Young, V. R., Dec 1 1997, In: FASEB Journal. 11, 3

  Research output: Contribution to journal › Article › peer-review

  • Arginine 100%
  • Oxidation Reaction 44%
  • Glutamic Acid 24%
  • Diet 19%
  • Plasma 15%

• Metabolism of L-arginine and the no pathway in septic children

  Argaman, Z., Noviski, N., Castillo-Rosas, L., Ritz, R., Rigatti, V., Ajami, A., Young, V. R. & Castillo, L., Dec 1 1997, In: FASEB Journal. 11, 3

  Research output: Contribution to journal › Article › peer-review

  • L-Arginine 100%
  • Arginine 72%
  • Pharmacological Metabolism 60%
  • Plasma 48%
  • Calorimetry 36%
• 1996

  Arginine: New and Exciting Developments for an "Old" Amino Acid

  Beaumier, L., Castillo, L., Yu, Y. M., Ajami, A. M. & Young, V. R., Sep 1996, In: Biomedical and Environmental Sciences. 9, 2-3, p. 296-315 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Arginine 100%
  • physiology 71%
  • Amino Acids 70%
  • biochemistry 39%
  • Human Subjects 38%
  57 Scopus citations

• Splanchnic uptake and oxidation of proljne in healthy subjects

  Castillo, L., Beaumier, L., Yu, Y. M. & Yjaing, V. R., Dec 1 1996, In: FASEB Journal. 10, 3

  Research output: Contribution to journal › Article › peer-review

  • Route of Application 100%
  • Viscera 75%
  • tracer techniques 53%
  • Urea 53%
  • Pharmacological Metabolism 52%

• Twenty-four-hour intravenous and oral tracer studies with L-[1-¹³C]phenylalanine and L-[3,3-²H₂]tyrosine at a tyrosine-free, generous phenylalanine intake in adults

  Sánchez, M., El-Khoury, A. E., Castillo, L., Chapman, T. E., Basile Filho, A., Beaumier, L. & Young, V. R., Apr 1996, In: American Journal of Clinical Nutrition. 63, 4, p. 532-545 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phenylalanine 100%
  • Tyrosine 83%
  • Hydroxylation 24%
  • Aromatic Amino Acids 9%
  • Leucine 7%
  34 Scopus citations

• Whole body nitric oxide synthesis in healthy men determined from [¹⁵N]arginine-to-[¹⁵N]citrulline labeling

  Castillo, L., Beaumier, L., Ajami, A. M. & Young, V. R., Oct 15 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 21, p. 11460-11465 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Citrulline 100%
  • Arginine 71%
  • Nitric Oxide 62%
  • Urea 26%
  • Nitrites 15%
  187 Scopus citations
• 1995

  Inhaled nitric oxide does not alter endotoxin-induced nitric oxide synthase activity during rat lung perfusion

  Kurrek, M. M., Castillo, L., Bloch, K. D., Tannenbaum, S. R. & Zapol, W. M., 1995, In: Journal of Applied Physiology. 79, 4, p. 1088-1092 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Endotoxins 100%
  • Nitric Oxide Synthase 97%
  • Nitric Oxide 81%
  • Perfusion 75%
  • Lung 53%
  12 Scopus citations

• Phenylalanine and tyrosine kinetics in young men throughout a continuous 24-h period, at a low phenylalanine intake

  Sánchez, M., El-Khoury, A. E., Castillo, L., Chapman, T. E. & Young, V. R., Mar 1995, In: American Journal of Clinical Nutrition. 61, 3, p. 555-570 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phenylalanine 100%
  • Tyrosine 83%
  • Hydroxylation 78%
  • Kinetics 65%
  • Aromatic Amino Acids 32%
  39 Scopus citations

• Plasma arginine, citrulline, and ornithine kinetics in adults, with observations on nitric oxide synthesis

  Castillo, L., Sanchez, M., Vogt, J., Chapman, T. E., Derojas-Walker, T. C., Tannenbaum, S. R., Ajami, A. M. & Young, V. R., 1995, In: American Journal of Physiology - Endocrinology and Metabolism. 268, 2 31-2, p. E360-E367

  Research output: Contribution to journal › Article › peer-review

  • Ornithine 100%
  • Citrulline 98%
  • Arginine 70%
  • Nitric Oxide 61%
  • Kinetics 55%
  113 Scopus citations

• Plasma arginine and leucine kinetics and urea production rates in burn patients

  Yu, Y. M., Young, V. R., Castillo, L., Chapman, T. E., Tompkins, R. G., Ryan, C. M. & Burke, J. F., May 1995, In: Metabolism. 44, 5, p. 659-666 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Leucine 100%
  • Urea 92%
  • Arginine 89%
  • Kinetics 70%
  • Ornithine 15%
  59 Scopus citations

• Urea cycle intermediate kinetics and nitrate excretion at normal and 'therapeutic' intakes of arginine in humans

  Beaumier, L., Castillo, L., Ajami, A. M. & Young, V. R., 1995, In: American Journal of Physiology - Endocrinology and Metabolism. 269, 5 32-5, p. E884-E896

  Research output: Contribution to journal › Article › peer-review

  • Nitrates 100%
  • Urea 86%
  • Arginine 84%
  • Ornithine 70%
  • Kinetics 66%
  83 Scopus citations