Li-Yen Huang, PhD

NCBA Vice Chair for Research

  • 4116 Citations
  • 34 h-Index
1971 …2019

Research output per year

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Research Output

  • 4116 Citations
  • 34 h-Index
  • 68 Article
  • 3 Review article
  • 1 Comment/debate
72 Scopus citations

Actions of endomorphins on synaptic transmission of Aδ-fibers in spinal cord dorsal horn neurons

Yajiri, Y. & Huang, L. Y. M., Jan 1 2000, In : Journal of Biomedical Science. 7, 3, p. 226-231 6 p.

Research output: Contribution to journalArticle

12 Scopus citations
89 Scopus citations

Activation of silent mechanoreceptive cat C and Aδ sensory neurons and their substance P expression following peripheral inflammation

Xu, G. Y., Huang, L. Y. M. & Zhao, Z. Q., Jan 1 2000, In : Journal of Physiology. 528, 2, p. 339-348 10 p.

Research output: Contribution to journalArticle

49 Scopus citations
74 Scopus citations
11 Scopus citations
48 Scopus citations
8 Scopus citations
1 Scopus citations

A symmetric model for the joint effects of scorpion toxin and an alkaloid neurotoxin

Ehrenstein, G., Huang, L. Y. M. & Moran, N., Jan 1 1982, In : Biophysical Journal. 37, 2 II, p. 324a

Research output: Contribution to journalArticle

Open Access
59 Scopus citations

Block of kainate receptor channels by Ca2+ in isolated spinal trigeminal neurons of rat

Gu, Y. & Huang, L. Y. M., May 1991, In : Neuron. 6, 5, p. 777-784 8 p.

Research output: Contribution to journalArticle

37 Scopus citations
59 Scopus citations

Ca2+-dependent exocytosis in the somata of dorsal root ganglion neurons

Huang, L. Y. M. & Neher, E., Jul 1996, In : Neuron. 17, 1, p. 135-145 11 p.

Research output: Contribution to journalArticle

225 Scopus citations
60 Scopus citations
8 Scopus citations

Communication between neuronal somata and satellite glial cells in sensory ganglia

Huang, L. Y. M., Gu, Y. & Chen, Y., Oct 1 2013, In : GLIA. 61, 10, p. 1571-1581 11 p.

Research output: Contribution to journalReview article

83 Scopus citations

Comparison of ionic selectivity of batrachotoxin-activated channels with different tetrodotoxin dissociation constants

Huang, L. Y. M., Catterall, W. A. & Ehrenstein, G., Jun 1 1979, In : Journal of General Physiology. 73, 6, p. 839-854 16 p.

Research output: Contribution to journalArticle

Open Access
42 Scopus citations
29 Scopus citations

Dynamic properties of polyelectrolyte calcium membranes

Mae Huang, L. Y. & Spangler, R. A., Dec 1 1977, In : The Journal of Membrane Biology. 36, 1, p. 311-335 25 p.

Research output: Contribution to journalArticle

14 Scopus citations

Dynorphin block of N-methyl-D-aspartate channels increases with the peptide length

Chen, L. & Huang, L. Y. M., Mar 1 1998, In : Journal of Pharmacology and Experimental Therapeutics. 284, 3, p. 826-831 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Dynorphin uses a non-opioid mechanism to potentiate N-methyl-D- aspartate currents in single rat periaqueductal gray neurons

Lai, S. L., Gu, Y. & Huang, L. Y. M., May 15 1998, In : Neuroscience Letters. 247, 2-3, p. 115-118 4 p.

Research output: Contribution to journalArticle

42 Scopus citations

Efficacy, Safety, and Feasibility of the Morphine Microdose Method in Community-Based Clinics

Wilkes, D., Orillosa, S. J., Hustak, E., Williams, C., Doulatram, G., Solanki, D. R., Garcia, E. A. & Huang, L-Y., Sep 1 2018, In : Pain medicine (Malden, Mass.). 19, 9, p. 1782-1789 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Efficiencies of transgene expression in nociceptive neurons through different routes of delivery of adeno-associated viral vectors

Xu, Y., Gu, Y., Wu, P., Li, G. W. & Huang, L. Y. M., Jun 10 2003, In : Human Gene Therapy. 14, 9, p. 897-906 10 p.

Research output: Contribution to journalArticle

66 Scopus citations

Electrical properties of acutely isolated, identified rat spinal dorsal horn projection neurons

Huang, L. Y. M., Dec 4 1987, In : Neuroscience Letters. 82, 3, p. 267-272 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Electroacupuncture downregulates P2X3 receptor expression in dorsal root ganglia of the spinal nerve-ligated rat

Liang, Y., Gu, Y., Shi, R., Li, G., Chen, Y. & Huang, L-Y., Jan 1 2019, In : Molecular pain. 15

Research output: Contribution to journalArticle

Open Access

Electron microscope observations on thick filaments in striated muscle from the lobster Homarus americanus

Hayes, D., Huang, M. & Zobel, C. R., Oct 1971, In : Journal of Ultrasructure Research. 37, 1-2, p. 17-30 14 p.

Research output: Contribution to journalArticle

17 Scopus citations

Epac and nociceptor sensitization

Huang, L-Y. & Gu, Y., Jun 1 2017, In : Molecular Pain. 13

Research output: Contribution to journalReview article

6 Scopus citations

Epac-protein kinase C alpha signaling in purinergic P2X3R-mediated hyperalgesia after inflammation

Gu, Y., Li, G., Chen, Y. & Huang, L-Y., Jul 1 2016, In : Pain. 157, 7, p. 1541-1550 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
11 Scopus citations

Gabapentin actions on N-methyl-D-aspartate receptor channels are protein kinase C-dependent

Gu, Y. & Huang, L. Y. M., Jun 23 2001, In : Pain. 93, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Gabapentin potentiates N-methyl-D-aspartate receptor mediated currents in rat GABAergic dorsal horn neurons

Gu, Y. & Huang, L. Y., May 24 2002, In : Neuroscience Letters. 324, 3, p. 177-180 4 p.

Research output: Contribution to journalArticle

33 Scopus citations

Gating kinetics of batrachotoxin-modified sodium channels in neuroblastoma cells determined from single-channel measurements

Huang, L. Y., Moran, N. & Ehrenstein, G., Jan 1 1984, In : Biophysical Journal. 45, 1, p. 313-322 10 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Hydrogen ions have multiple effects on the excitability of cultured mammalian neurons

Gruol, D. L., Barker, J. L., Mae Huang, L. Y., Ferguson MacDonald, J. & Smith, T. G., Feb 3 1980, In : Brain Research. 183, 1, p. 247-252 6 p.

Research output: Contribution to journalArticle

65 Scopus citations

Identification of spinothalamic tract cells in fresh, unfixed rat spinal cord

Huang, L. Y. M., Carlton, S. M. & Willis, W. D., Jul 1985, In : Journal of Neuroscience Methods. 14, 2, p. 91-96 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Inflammation induces Epac-protein kinase C alpha and epsilon signaling in TRPV1-mediated hyperalgesia

Gu, Y., Li, G. & Huang, L-Y., Nov 1 2018, In : Pain. 159, 11, p. 2383-2393 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Interaction between batrachotoxin and yohimbine

Huang, L. Y., Ehrenstein, G. & Catterall, W. A., Jan 1 1978, In : Biophysical Journal. 23, 2, p. 219-231 13 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Interaction between batrachotoxin and yohimbine in cultured neuroblastoma cells

Huang, L. M., Ehrenstein, G. & Catterall, W. A., Jan 1 1977, In : Biophysical journal. 17, 2, p. 208a

Research output: Contribution to journalArticle

1 Scopus citations

Ionic currents in retrogradely labeled trigeminothalamic neurons in slices of rat medulla

Chen, L. & Huang, L. Y. M., Mar 2 1990, In : Neuroscience Letters. 110, 1-2, p. 66-71 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Is naloxone a specific opiate antagonist

Gruol, D. L., Barker, J. L., Huang, L. M. & Smith, T. G., Jan 1 1979, In : Federation Proceedings. 38, 3 II, p. No. 6184

Research output: Contribution to journalArticle

Local anesthetics QX 572 and benzocaine act at separate sites on the batrachotoxin-activated sodium Channel

Mae Huang, L. Y. & Ehrenstein, G., Feb 1 1981, In : Journal of General Physiology. 77, 2, p. 137-153 17 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Mechanisms underlying enhanced P2X receptor-mediated responses in the neuropathic pain state

Chen, Y., Li, G. W., Wang, C., Gu, Y. & Huang, L. Y. M., Dec 15 2005, In : Pain. 119, 1-3, p. 38-48 11 p.

Research output: Contribution to journalArticle

91 Scopus citations

Mechanisms underlying purinergic P2X3 receptor-mediated mechanical allodynia induced in diabetic rats

Xu, G. Y., Li, G., Liu, N. & Huang, L. Y. M., Aug 18 2011, In : Molecular pain. 7, 60.

Research output: Contribution to journalArticle

48 Scopus citations

Mechanism underlying increased neuronal activity in the rat ventrolateral periaqueductal grey by a μ-opioid

Chiou, L. C. & Huang, L. Y. M., Jul 15 1999, In : Journal of Physiology. 518, 2, p. 551-559 9 p.

Research output: Contribution to journalArticle

54 Scopus citations

Modulation of glycine affinity for NMDA receptors by extracellular Ca2+ in trigeminal neurons

Gu, Y. & Huang, L. Y. M., Jan 1 1994, In : Journal of Neuroscience. 14, 7, p. 4561-4570 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Modulation of glycine receptor chloride channels by cAMP-dependent protein kinase in spinal trigeminal neurons

Song, Y. & Huang, L. Y. M., Jan 1 1990, In : Nature. 348, 6298, p. 242-245 4 p.

Research output: Contribution to journalArticle

95 Scopus citations

Neuronal soma-satellite glial cell interactions in sensory ganglia and the participation of purinergic receptors

Gu, Y., Chen, Y., Zhang, X., Li, G. W., Wang, C. & Huang, L. Y. M., Feb 1 2010, In : Neuron Glia Biology. 6, 1, p. 53-62 10 p.

Research output: Contribution to journalReview article

55 Scopus citations
206 Scopus citations

Origin of thalamically projecting somatosensory relay neurons in the immature rat

Huang, L. Y. M., Aug 21 1989, In : Brain Research. 495, 1, p. 108-114 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
27 Scopus citations