Projects per year
Fingerprint Dive into the research topics where Louise Prakash is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 15 Similar Profiles
DNA-Directed DNA Polymerase
Medicine & Life Sciences
Yeasts
Medicine & Life Sciences
Saccharomyces cerevisiae
Medicine & Life Sciences
DNA
Medicine & Life Sciences
DNA Repair
Medicine & Life Sciences
Yeast
Chemical Compounds
Genes
Medicine & Life Sciences
Nucleotides
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2008 2021
Structure and Mechanism of Multisubunit Complexes of DNA Polymerase Zeta
Icahn School of Medicine at Mount Sinai
9/15/18 → 8/31/20
Project: Other project
Structure and Function of DNA Polymerase Lambda Opposite DNA Lesions Which Disrupt Watson-Crick Base Pairing
National Inst of General Medical Science
12/18/17 → 11/30/21
Project: Other project
EL II: Role of Cohesin in Lesion Bypass in DNA Damage Human Cells
National Inst of Environmental Health Sc
5/16/14 → 2/29/20
Project: Other project
Role of DNA Polymerase eta In ErrorFree ByPass of DNA Lesions and Cancer Prevention
Icahn School of Medicine at Mount Sinai
12/1/10 → 11/30/15
Project: Other project
Research Output 1966 2019
- 22875 Citations
- 89 h-Index
- 265 Article
Cryo-EM structure and dynamics of eukaryotic DNA polymerase δ holoenzyme
Jain, R., Rice, W. J., Malik, R., Johnson, R. E., Prakash, L., Prakash, S., Ubarretxena-Belandia, I. & Aggarwal, A. K., Oct 1 2019, In : Nature Structural and Molecular Biology. 26, 10, p. 955-962 8 p.Research output: Contribution to journal › Article
Holoenzymes
DNA-Directed DNA Polymerase
DNA
Yeasts
Exonucleases
2
Citations
(Scopus)
DNA polymerase θ accomplishes translesion synthesis opposite 1, N 6 -ethenodeoxyadenosine with a remarkably high fidelity in human cells
Yoon, J. H., Johnson, R. E., Prakash, L. & Prakash, S., Mar 1 2019, In : Genes and Development. 33, 5-6, p. 282-287 6 p.Research output: Contribution to journal › Article
Open Access
DNA-Directed DNA Polymerase
Base Pairing
Catalytic Domain
Nucleotides
1,N(6)-ethenodeoxyadenosine
7
Citations
(Scopus)
Error-Prone Replication through UV Lesions by DNA Polymerase θ Protects against Skin Cancers
Yoon, J. H., McArthur, M. J., Park, J., Basu, D., Wakamiya, M., Prakash, L. & Prakash, S., Mar 7 2019, In : Cell. 176, 6, p. 1295-1309.e15Research output: Contribution to journal › Article
Skin Neoplasms
DNA-Directed DNA Polymerase
Skin
Mutation
Carcinogenesis
Structural insights into mutagenicity of anticancer nucleoside analog cytarabine during replication by DNA polymerase η
Rechkoblit, O., Johnson, R. E., Buku, A., Prakash, L., Prakash, S. & Aggarwal, A. K., Dec 1 2019, In : Scientific reports. 9, 1, 16400.Research output: Contribution to journal › Article
Open Access
Cytarabine
DNA-Directed DNA Polymerase
Nucleosides
Acute Myeloid Leukemia
Mutagenesis
Translesion synthesis DNA polymerases η, ι, and ν promote mutagenic replication through the anticancer nucleoside cytarabine
Yoon, J. H., Choudhury, J. R., Prakash, L. & Prakash, S., Jan 1 2019, In : Journal of Biological Chemistry. 294, 50, p. 19048-19054 7 p.Research output: Contribution to journal › Article
Cytarabine
DNA-Directed DNA Polymerase
Nucleosides
DNA
Acute Myeloid Leukemia