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Research Strategic Pillar
The Chief Research Officer, has determined that UTMB research should be prioritized into six health communities. This researcher has received the following badge(s):
Research Strategic Pillar Keywords
- Life Span Health
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Collaborations and top research areas from the last five years
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Mechanisms for the high fidelity of translesion synthesis by Y-family DNA polymerases in human cells
Prakash, L. (PI)
National Institute of General Medical Sciences ( Award #5R35GM14836404)
2/1/23 → 11/30/27
Project: Research project
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Structure and Function of DNA Polymerase Lambda Opposite DNA Lesions Which Disrupt Watson-Crick Base Pairing
Prakash, L. (PI)
National Institute of General Medical Sciences ( Award #5R01GM12608704)
12/18/17 → 11/30/22
Project: Research project
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EL II: Role of cohesin in lesion bypass in DNA damage human cells
Prakash, L. (PI)
National Institute of Environmental Health Sciences ( Award #5R01ES02294805)
5/16/14 → 2/28/19
Project: Research project
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Bypass of DNA lesions by translesion synthesis in yeast
Prakash, L. (PI)
National Cancer Institute ( Award #5R01CA10765042)
3/1/10 → 1/31/14
Project: Research project
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Cryo-EM structure of the Rev1–Polζ holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis
Malik, R., Johnson, R. E., Ubarretxena-Belandia, I., Prakash, L., Prakash, S. & Aggarwal, A. K., Sep 2024, In: Nature Structural and Molecular Biology. 31, 9, p. 1394-1403 10 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Link opens in a new tab Scopus citations -
WRN exonuclease imparts high fidelity on translesion synthesis by Y family DNA polymerases
Yoon, J. H., Sellamuthu, K., Prakash, L. & Prakash, S., 2024, In: Genes and Development. 38, 5-6, p. 213-232 20 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Link opens in a new tab Scopus citations -
DNA polymerase ε leading strand signature mutations result from defects in its proofreading activity
Johnson, R., Prakash, L. & Prakash, S., Jul 2023, In: Journal of Biological Chemistry. 299, 7, 104913.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Mismatch repair operates at the replication fork in direct competition with mismatch extension by DNA polymerase δ
Klassen, R., Gangavarapu, V., Johnson, R., Prakash, L. & Prakash, S., Apr 2023, In: Journal of Biological Chemistry. 299, 4, 104598.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Yeast 9-1-1 complex acts as a sliding clamp for DNA synthesis by DNA polymerase ε
Acharya, N., Prakash, L. & Prakash, S., Jan 2023, In: Journal of Biological Chemistry. 299, 1, 102727.Research output: Contribution to journal › Article › peer-review
Open Access5 Link opens in a new tab Scopus citations