Luis Pacheco, MD

Director, Maternal Critical Care Services

  • 695 Citations
  • 16 h-Index
20032019
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Research Output 2003 2019

  • 695 Citations
  • 16 h-Index
  • 52 Article
  • 5 Chapter
  • 4 Review article
  • 2 Letter
Article
6 Citations (Scopus)

Acute antihypertensive therapy in pregnancy-induced hypertension: Is nicardipine the answer?

Vadhera, R., Pacheco, L. & Hankins, G., Aug 2009, In : American Journal of Perinatology. 26, 7, p. 495-499 5 p.

Research output: Contribution to journalArticle

Nicardipine
Pregnancy Induced Hypertension
Antihypertensive Agents
Pregnancy
Pre-Eclampsia

Acute Management of Ischemic Stroke During Pregnancy

Pacheco, L., Hankins, G., Saad, A. & Saade, G., May 1 2019, In : Obstetrics and gynecology. 133, 5, p. 933-939 7 p.

Research output: Contribution to journalArticle

Tissue Plasminogen Activator
Stroke
Pregnancy
Obstetrics
Head
5 Citations (Scopus)

Acute myocardial infarction during pregnancy

Pacheco, L., Saade, G. & Hankins, G., 2014, In : Clinical Obstetrics and Gynecology. 57, 4, p. 835-843 9 p.

Research output: Contribution to journalArticle

Myocardial Infarction
Pregnancy
Fibrinolytic Agents
Maternal Mortality
Platelet Aggregation Inhibitors

Amniotic fluid embolism: principles of early clinical management

Pacheco, L., Clark, S. L., Klassen, M. & Hankins, G. D. V., Jan 1 2019, (Accepted/In press) In : American journal of obstetrics and gynecology.

Research output: Contribution to journalArticle

Amniotic Fluid Embolism
Cardiopulmonary Resuscitation
Ventricular Dysfunction
Extracorporeal Membrane Oxygenation
Pregnancy Complications
26 Citations (Scopus)

Amniotic fluid embolism: Diagnosis and management

Pacheco, L., Saade, G., Hankins, G. & Clark, S. L., Oct 27 2015, (Accepted/In press) In : American Journal of Obstetrics and Gynecology.

Research output: Contribution to journalArticle

Amniotic Fluid Embolism
Cardiopulmonary Resuscitation
Guidelines
Heart Arrest
Advanced Cardiac Life Support
22 Citations (Scopus)

An update on the use of massive transfusion protocols in obstetrics

Pacheco, L., Saade, G., Costantine, M., Clark, S. L. & Hankins, G., Mar 1 2016, In : American Journal of Obstetrics and Gynecology. 214, 3, p. 340-344 5 p.

Research output: Contribution to journalArticle

Resuscitation
Obstetrics
Hemostatics
Hemorrhage
Tranexamic Acid
8 Citations (Scopus)

Burns in pregnancy

Pacheco, L., Gei, A. F., VanHook, J. W., Saade, G. & Hankins, G., Nov 2005, In : Obstetrics and Gynecology. 106, 5 II, p. 1210-1212 3 p.

Research output: Contribution to journalArticle

Burns
Pregnancy
Wounds and Injuries
Hemodynamics
Airway Management

Cardiovascular disease in pregnancy

Hill, A. J. & Pacheco, L., Nov 2012, In : NeoReviews. 13, 11

Research output: Contribution to journalArticle

Peripartum Period
Cardiovascular Diseases
Cardiomyopathies
Pregnancy
Heart Diseases
16 Citations (Scopus)

Controversies in the Management of Placenta Accreta

Pacheco, L. & Gei, A. F., Jun 2011, In : Obstetrics and Gynecology Clinics of North America. 38, 2, p. 313-322 10 p.

Research output: Contribution to journalArticle

Placenta Accreta
Peripartum Period
Interventional Radiology
Placentation
Hemodilution

Critical care obstetrics

Pacheco, L., 2014, In : Clinical Obstetrics and Gynecology. 57, 4, p. 790 1 p.

Research output: Contribution to journalArticle

Critical Care
Obstetrics
6 Citations (Scopus)

Customized versus population fetal growth norms and adverse outcomes associated with small for gestational age infants in a high-risk cohort

Moussa, H. N., Wu, Z. H., Han, Y., Pacheco, L., Blackwell, S. C., Sibai, B. M., Saade, G. & Costantine, M., Sep 28 2014, In : American Journal of Perinatology. 32, 7, p. 621-626 6 p.

Research output: Contribution to journalArticle

Small for Gestational Age Infant
Population Growth
Fetal Development
Gestational Age
Population
45 Citations (Scopus)

Cutting-edge advances in the medical management of obstetrical hemorrhage

Pacheco, L., Saade, G., Gei, A. F. & Hankins, G., Dec 2011, In : American Journal of Obstetrics and Gynecology. 205, 6, p. 526-532 7 p.

Research output: Contribution to journalArticle

Interventional Radiology
Factor VIIa
Hemodilution
Hemorrhagic Shock
Hemostatics
1 Citation (Scopus)

Damage-control surgery for obstetric hemorrhage

Pacheco, L., Lozada, M. J., Saade, G. & Hankins, G., Jan 1 2018, In : Obstetrics and Gynecology. 132, 2, p. 423-427 5 p.

Research output: Contribution to journalArticle

Obstetric Surgical Procedures
Hemorrhage
Operating Rooms
Acidosis
Hemostasis
1 Citation (Scopus)

Discussion: 'Maternal hypotension during cesarean section' by Maayan-Metzger et al

Blackwell, S. C., Pacheco, L., Chiossi, G., Lee, T. & Nguyen, T., Jan 2010, In : American Journal of Obstetrics and Gynecology. 202, 1

Research output: Contribution to journalArticle

Cesarean Section
Hypotension
Mothers
27 Citations (Scopus)

Does information available at delivery improve the accuracy of predicting vaginal birth after cesarean? validation of the published models in an independent patient cohort

Costantine, M., Fox, K. A., Pacheco, L., Mateus, J., Hankins, G., Grobman, W. A. & Saade, G., 2011, In : American Journal of Perinatology. 28, 4, p. 293-298 6 p.

Research output: Contribution to journalArticle

Vaginal Birth after Cesarean
Trial of Labor
ROC Curve
Pregnant Women
Cohort Studies
1 Citation (Scopus)

Effect of Low-Dose Aspirin on the Time of Onset of Preeclampsia and Time of Delivery

Dixon, L. L., Marrs, C., Costantine, M., Pacheco, L., Saade, G. & Chiossi, G., Mar 27 2017, (Accepted/In press) In : American Journal of Perinatology.

Research output: Contribution to journalArticle

Pre-Eclampsia
Aspirin
Gestational Age
Multivariate Analysis
Randomized Controlled Trials
9 Citations (Scopus)

Embryonal mitochondrial DNA: relationship to embryo quality and transfer outcomes

Klimczak, A. M., Pacheco, L., Lewis, K., Massahi, N., Richards, J. P., Kearns, W. G., Saad, A. & Crochet, J. R., Mar 5 2018, (Accepted/In press) In : Journal of Assisted Reproduction and Genetics. p. 1-7 7 p.

Research output: Contribution to journalArticle

Embryo Transfer
Mitochondrial DNA
Embryonic Structures
Blastocyst
Female Infertility

Erratum: The use of a continuous infusion of epinephrine for anaphylactic shock during labor (Obstetrics and Gynecology (2003) 102 (1332-1335))

Gei, A. F., Pacheco, L., Vanhook, J. W. & Hankins, G., Apr 2004, In : Obstetrics and Gynecology. 103, 4, p. 799 1 p.

Research output: Contribution to journalArticle

Obstetric Labor
Anaphylaxis
Gynecology
Epinephrine
4 Citations (Scopus)

Extracorporeal membrane oxygenation (ECMO) during pregnancy and postpartum

Pacheco, L., Saade, G. & Hankins, G., Jan 1 2017, (Accepted/In press) In : Seminars in Perinatology.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Postpartum Period
Pregnancy
Technology
11 Citations (Scopus)

Extracorporeal Membrane Oxygenation in Pregnant and Postpartum Women With H1N1-Related Acute Respiratory Distress Syndrome

Saad, A., Rahman, M., Maybauer, D. M., Fraser, J. F., Costantine, M., Pacheco, L. & Maybauer, M. O., Feb 1 2016, In : Obstetrics and Gynecology. 127, 2, p. 241-247 7 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Adult Respiratory Distress Syndrome
Postpartum Period
Pregnant Women
Observational Studies
2 Citations (Scopus)

Familial hypertriglyceridemia in pregnancy

Hill, A. J., Pacheco, L., Saade, G. & Hankins, G., Apr 2014, In : International Journal of Gynecology and Obstetrics. 125, 1, p. 80-81 2 p.

Research output: Contribution to journalArticle

Hyperlipoproteinemia Type IV
Pregnancy Complications
Hypertriglyceridemia
Pancreatitis
Young Adult
Neonatal Alloimmune Thrombocytopenia
56 Citations (Scopus)

Fetal and neonatal alloimmune thrombocytopenia: A management algorithm based on risk stratification

Pacheco, L., Berkowitz, R. L., Moise, K. J., Bussel, J. B., McFarland, J. G. & Saade, G., Nov 2011, In : Obstetrics and Gynecology. 118, 5, p. 1157-1163 7 p.

Research output: Contribution to journalArticle

Neonatal Alloimmune Thrombocytopenia
Fetal Blood
Fetus
Intracranial Hemorrhages
Intravenous Immunoglobulins
1 Citation (Scopus)

Fetal assessment near the limits of viability

Hankins, G., Pacheco, L. & Soo-Tung Wen, T., Dec 2013, In : Seminars in Perinatology. 37, 6, p. 401-403 3 p.

Research output: Contribution to journalArticle

Gestational Age
Pregnancy Tests
Pregnancy
Fetal Development
Decision Making
3 Citations (Scopus)

Forceps: Still an option?

Gei, A. F. & Pacheco, L., Feb 2008, In : Current Women's Health Reviews. 4, 1, p. 56-75 20 p.

Research output: Contribution to journalArticle

Deceleration
Surgical Instruments
Head
Pregnancy
1 Citation (Scopus)

Hemostatic Resuscitation in Peripartum Hysterectomy Pre- and Postmassive Transfusion Protocol Initiation

Dutta, E. H., Poole, A. T., Behnia, F., Dunn, H. E., Clark, S., Pacheco, L., Saade, G. & Hankins, G., Jan 12 2017, (Accepted/In press) In : American Journal of Perinatology.

Research output: Contribution to journalArticle

Peripartum Period
Hemostatics
Hysterectomy
Resuscitation
Erythrocytes
25 Citations (Scopus)

High risk human papillomavirus at entry to prenatal care and risk of preeclampsia

McDonnold, M., Dunn, H., Hester, A., Pacheco, L., Hankins, G., Saade, G. & Costantine, M., Feb 2014, In : American Journal of Obstetrics and Gynecology. 210, 2

Research output: Contribution to journalArticle

Prenatal Care
Pre-Eclampsia
Papanicolaou Test
Blood Pressure
Vaccination
2 Citations (Scopus)

Management of ectopic parathyroid adenoma in pregnancy

Saad, A., Pacheco, L. & Costantine, M., 2014, In : Obstetrics and Gynecology. 124, 2 PART2, p. 478-480 3 p.

Research output: Contribution to journalArticle

Parathyroid Neoplasms
Hypercalcemia
Pregnancy
Adenoma
Primary Hyperparathyroidism
65 Citations (Scopus)

Management of pulmonary arterial hypertension during pregnancy: A retrospective, multicenter experience

Duarte, A., Thomas, S., Safdar, Z., Torres, F., Pacheco, L., Feldman, J. & DeBoisblanc, B., May 2013, In : Chest. 143, 5, p. 1330-1336 7 p.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Pregnancy
Maternal Mortality
Parturition
Postpartum Period
9 Citations (Scopus)

Management of the Jehovah's witness in obstetrics and gynecology: A comprehensive medical, ethical, and legal approach

Zeybek, B., Childress, A. M., Kilic, G., Phelps, J., Pacheco, L., Carter, M. & Borahay, M. A., Aug 1 2016, In : Obstetrical and Gynecological Survey. 71, 8, p. 488-500 13 p.

Research output: Contribution to journalArticle

Jehovah's Witnesses
Gynecology
Obstetrics
Blood Transfusion
Oxygen
8 Citations (Scopus)

Management of uterine hyperstimulation with concomitant use of oxytocin and terbutaline

Pacheco, L., Rosen, M. P., Gei, A. F., Saade, G. & Hankins, G., Aug 2006, In : American Journal of Perinatology. 23, 6, p. 377-380 4 p.

Research output: Contribution to journalArticle

Terbutaline
Oxytocin
Chorioamnionitis
Apgar Score
Cesarean Section
1 Citation (Scopus)

Maternal hypotension during cesarean section: Maayan-Metzger et al

Blackwell, S. C., Pacheco, L., Chiossi, G., Lee, T. & Nguyen, T., Jan 2010, In : American Journal of Obstetrics and Gynecology. 202, 1, p. 93-94 2 p.

Research output: Contribution to journalArticle

Cesarean Section
Hypotension
Mothers
43 Citations (Scopus)

Maternal mortality, near misses, and severe morbidity: Lowering rates through designated levels of maternity care

Hankins, G., Clark, S. L., Pacheco, L., O'Keeffe, D., D'Alton, M. & Saade, G., Oct 2012, In : Obstetrics and Gynecology. 120, 4, p. 929-934 6 p.

Research output: Contribution to journalArticle

Maternal Mortality
Mothers
Morbidity
Perinatal Care
Neonatology
5 Citations (Scopus)

Maternal obesity is associated with chorioamnionitis and earlier indicated preterm delivery among expectantly managed women with preterm premature rupture of membranes

Hadley, E. E., Discacciati, A., Costantine, M., Munn, M., Pacheco, L., Saade, G. & Chiossi, G., Sep 22 2017, (Accepted/In press) In : Journal of Maternal-Fetal and Neonatal Medicine. p. 1-8 8 p.

Research output: Contribution to journalArticle

Chorioamnionitis
Obesity
Mothers
Labor Onset
Pregnancy
5 Citations (Scopus)

Mechanical ventilation during pregnancy: Sedation, analgesia, and paralysis

Pacheco, L., Saade, G. & Hankins, G., 2014, In : Clinical Obstetrics and Gynecology. 57, 4, p. 844-850 7 p.

Research output: Contribution to journalArticle

Neuromuscular Blocking Agents
Critical Care
Hypnotics and Sedatives
Artificial Respiration
Paralysis

Medical management of postpartum hemorrhage: An update

Pacheco, L., Saade, G. & Hankins, G., Jan 1 2018, (Accepted/In press) In : Seminars in Perinatology.

Research output: Contribution to journalArticle

Postpartum Hemorrhage
Hemorrhage
Tranexamic Acid
Blood Coagulation Factors
Maternal Mortality
5 Citations (Scopus)

Operative Vaginal Deliveries: Practical Aspects

Gei, A. F. & Pacheco, L., Jun 2011, In : Obstetrics and Gynecology Clinics of North America. 38, 2, p. 323-349 27 p.

Research output: Contribution to journalArticle

Obstetrics
Art
Vacuum
Gynecology
Surgical Instruments
6 Citations (Scopus)

Passive leg raising during pregnancy

Marques, N. R., Martinello, C., Kramer, G., Costantine, M., Vadhera, R., Saade, G., Hankins, G. & Pacheco, L., 2015, In : American Journal of Perinatology. 32, 4, p. 393-397 5 p.

Research output: Contribution to journalArticle

Leg
Cardiac Output
Pregnancy
Heart Rate
Arterial Pressure

Performance of Risk Assessment Models for Peripartum Thromboprophylaxis

Tran, J. P., Stribling, S. S., Ibezim, U. C., Omere, C., McEnery, K. A., Pacheco, L., Hankins, G., Saade, G. & Saad, A., Jan 1 2018, (Accepted/In press) In : Reproductive Sciences.

Research output: Contribution to journalArticle

Peripartum Period
Numbers Needed To Treat
Confidence Intervals
Pregnancy
Postpartum Period
17 Citations (Scopus)

Pharmacokinetics of corticosteroids during pregnancy

Pacheco, L., Ghulmiyyah, L. M., Snodgrass, W. R. & Hankins, G., Feb 2007, In : American Journal of Perinatology. 24, 2, p. 79-82 4 p.

Research output: Contribution to journalArticle

Adrenal Cortex Hormones
Pharmacokinetics
Pregnancy
Glucocorticoids
Therapeutic Uses
28 Citations (Scopus)

Proposed diagnostic criteria for the case definition of amniotic fluid embolism in research studies

Clark, S. L., Romero, R., Dildy, G. A., Callaghan, W. M., Smiley, R. M., Bracey, A. W., Hankins, G., D'Alton, M. E., Foley, M., Pacheco, L., Vadhera, R., Herlihy, J. P., Berkowitz, R. L. & Belfort, M. A., Oct 1 2016, In : American Journal of Obstetrics and Gynecology. 215, 4, p. 408-412 5 p.

Research output: Contribution to journalArticle

Amniotic Fluid Embolism
Research
Hope
Biomarkers
National Institute of Child Health and Human Development (U.S.)
77 Citations (Scopus)

Putting the "m" back in maternal-fetal medicine

D'Alton, M. E., Bonanno, C. A., Berkowitz, R. L., Brown, H. L., Copel, J. A., Cunningham, F. G., Garite, T. J., Gilstrap, L. C., Grobman, W. A., Hankins, G., Hauth, J. C., Iriye, B. K., Macones, G. A., Martin, J. N., Martin, S. R., Menard, M. K., O'Keefe, D. F., Pacheco, L., Riley, L. E., Saade, G. & 1 others, Spong, C. Y., Jun 2013, In : American Journal of Obstetrics and Gynecology. 208, 6, p. 442-448 7 p.

Research output: Contribution to journalArticle

Mothers
Medicine
Maternal Mortality
Morbidity
Maternal Death
1 Citation (Scopus)

Reconsidering the switch from low-molecular-weight heparin to unfractionated heparin during pregnancy

Pacheco, L., Saade, G., Costantine, M., Vadhera, R. & Hankins, G., 2014, In : American Journal of Perinatology. 31, 8, p. 655-658 4 p.

Research output: Contribution to journalArticle

Low Molecular Weight Heparin
Heparin
Pregnancy
Anesthesia
Spinal Epidural Hematoma
13 Citations (Scopus)

Severe sepsis during pregnancy

Pacheco, L., Saade, G. & Hankins, G., 2014, In : Clinical Obstetrics and Gynecology. 57, 4, p. 827-834 8 p.

Research output: Contribution to journalArticle

Resuscitation
Sepsis
Pregnancy
Fluid Therapy
Vasopressins
2 Citations (Scopus)

SMFM Consult Series #47: Sepsis during pregnancy and the puerperium

Society for Maternal-Fetal Medicine (SMFM) pubs@smfm.org Society for Maternal-Fetal Medicine: Publications Committee, Apr 1 2019, In : American journal of obstetrics and gynecology. 220, 4, p. B2-B10

Research output: Contribution to journalArticle

Postpartum Period
Sepsis
Pregnancy
Resuscitation
Hypotension

Stroke Volume Recruitability during the Third Trimester of Pregnancy

Herrera, S., Kuhlmann-Capek, M. J., Rogan, S. C., Saad, A., Saade, G., Hankins, G. & Pacheco, L., Dec 26 2017, (Accepted/In press) In : American Journal of Perinatology.

Research output: Contribution to journalArticle

Starlings
Third Pregnancy Trimester
Vascular Resistance
Stroke Volume
Pregnant Women
8 Citations (Scopus)

The role of human decay-accelerating factor in the pathogenesis of preterm labor

Pacheco, L., Hankins, G., Costantine, M., Anderson, G. D., Pawelczyk, E., Nowicki, S. & Nowicki, B. J., 2011, In : American Journal of Perinatology. 28, 7, p. 565-570 6 p.

Research output: Contribution to journalArticle

CD55 Antigens
Premature Obstetric Labor
Leukocytes
Complement Inactivating Agents
Control Groups
21 Citations (Scopus)

The role of massive transfusion protocols in obstetrics

Pacheco, L., Saade, G., Costantine, M., Clark, S. L. & Hankins, G., 2013, In : American Journal of Perinatology. 30, 1, p. 1-4 4 p.

Research output: Contribution to journalArticle

Resuscitation
Obstetrics
Hemostatics
Hemorrhage
Maternal Mortality
30 Citations (Scopus)

The use of a continuous infusion of epinephrine for anaphylactic shock during labor

Gei, A. F., Pacheco, L., Vanhook, J. W. & Hankins, G., Dec 2003, In : Obstetrics and Gynecology. 102, 6, p. 1332-1335 4 p.

Research output: Contribution to journalArticle

Anaphylaxis
Epinephrine
Urticaria
Mothers
Angioedema