Research output per year
Research output per year
- 1 - 50 out of 145 results
Search results
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2024
Lack of the IFN-γ signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions
Liang, Y., Wang, H., Sun, K., Sun, J. & Soong, L., May 2024, In: PLoS pathogens. 20, 5 May, p. e1012020 e1012020.Research output: Contribution to journal › Article › peer-review
Open Access -
Pathological Responses in Asian House Shrews (Suncus murinus) to the Naturally Acquired Orientia tsutsugamushi Infection
Balasubramanian, T., Sambath, U., Radja, R. D., Thangaraj, G., Devaraju, P., Srinivasan, L., Srinivasan, P., Nair, M. G., Raja, K., Lakkawar, A. W. & Soong, L., Apr 7 2024, In: Microorganisms. 12, 4, 748.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The alarmin IL-33 exacerbates pulmonary inflammation and immune dysfunction in SARS-CoV-2 infection
Wang, H., Hosakote Madaiah, Y., Boor, P. J., Yang, J., Zhang, Y., Yu, X., Gonzales, C., Levine, C. B., McLellan, S., Cloutier, N., Xie, X., Shi, P.-Y., Ren, P., Hu, H., Sun, K., Soong, L., Sun, J. & Liang, Y., Jun 21 2024, In: iScience. 27, 6, p. 110117 110117.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Alterations in germinal center formation and B cell activation during severe Orientia tsutsugamushi infection in mice
Gonzales, C., Liang, Y., Fisher, J., Card, G., Sun, J. & Soong, L., May 2023, In: PLoS neglected tropical diseases. 17, 5, e0011090.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Brain transcriptomics reveal the activation of neuroinflammation pathways during acute Orientia tsutsugamushi infection in mice
Liang, Y., Aditi, Onyoni, F., Wang, H., Gonzales, C., Sunyakumthorn, P., Wu, P., Samir, P. & Soong, L., Jun 21 2023, In: Frontiers in immunology. 14, p. 1194881 1194881.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Differential cellular immune responses against Orientia tsutsugamushi Karp and Gilliam strains following acute infection in mice
Thiriot, J. D., Liang, Y., Gonzales, C., Sun, J., Yu, X. & Soong, L., Dec 2023, In: PLoS neglected tropical diseases. 2023-December, e0011445.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Malnutrition-related parasite dissemination from the skin in visceral leishmaniasis is driven by PGE2-mediated amplification of CCR7-related trafficking of infected inflammatory monocytes
Osorio, E. Y., Uscanga-Palomeque, A., Patterson, G. T., Cordova, E., Travi, B., Soong, L. & Melby, P. C., Jan 11 2023, In: PLoS neglected tropical diseases. 17, 1, e0011040.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Metformin restrains ZIKV replication and alleviates virus-induced inflammatory responses in microglia
Wang, X., Wang, H., Yi, P., Baker, C., Casey, G., Xie, X., Luo, H., Cai, J., Fan, X., Soong, L., Hu, H., Shi, P.-Y., Liang, Y. & Sun, J., Aug 2023, In: International Immunopharmacology. 121, 110512.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Orientia tsutsugamushi Infection Stimulates Syk-Dependent Responses and Innate Cytosolic Defenses in Macrophages
Fisher, J., Gonzales, C., Chroust, Z., Liang, Y. & Soong, L., Jan 2023, In: Pathogens. 12, 1, 53.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2022
Atomic structure of the Leishmania spp. Hsp100 N-domain
Mercado, J. M., Lee, S., Chang, C., Sung, N., Soong, L., Catic, A. & Tsai, F. T. F., Jun 2022, In: Proteins: Structure, Function and Bioinformatics. 90, 6, p. 1242-1246 5 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
CCR7/dendritic cell axis mediates early bacterial dissemination in Orientia tsutsugamushi-infected mice
Liang, Y., Wang, H., Gonzales, C., Thiriot, J., Sunyakumthorn, P., Melby, P. C., Sun, J. & Soong, L., Dec 22 2022, In: Frontiers in immunology. 13, 1061031.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Distinct Role of TNFR1 and TNFR2 in Protective Immunity Against Orientia tsutsugamushi Infection in Mice
Liang, Y., Fisher, J., Gonzales, C., Trent, B., Card, G., Sun, J., Tumanov, A. V. & Soong, L., Apr 11 2022, In: Frontiers in immunology. 13, 867924.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models
Hajnik, R. L., Plante, J., Liang, Y., Alameh, M. G., Tang, J., Bonam, S. R., Zhong, C., Adam, A., Scharton, D., Rafael, G. H., Liu, Y., Hazell, N. C., Sun, J., Soong, L., Shi, P.-Y., Wang, T., Walker, D. H., Sun, J., Weissman, D. & Weaver, S. C. & 2 others, , Sep 14 2022, In: Science Translational Medicine. 14, 662, abq1945.Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
Histone Deacetylase Isoforms Differentially Modulate Inflammatory and Autoantibody Responses in a Mouse Model of Myasthenia Gravis
Bahauddin, A., Ivannikov, M., Wang, Z., Jamaluddin, M., Curtis, K., Ibtehaj, N., Yeager, L., Soong, L., Fang, X. & Huda, R., Feb 10 2022, In: Frontiers in Neurology. 12, 804113.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Host transcriptomic profiling of CD-1 outbred mice with severe clinical outcomes following infection with Orientia tsutsugamushi
Thiriot, J., Liang, Y., Fisher, J., Walker, D. H. & Soong, L., Nov 2022, In: PLoS neglected tropical diseases. 16, 11, e0010459.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
IL-33 activates mTORC1 and modulates glycolytic metabolism in CD8+ T cells
Liang, Y., Wang, X., Wang, H., Yang, W., Yi, P., Soong, L., Cong, Y., Cai, J., Fan, X. & Sun, J., Jan 2022, In: Immunology. 165, 1, p. 61-73 13 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
The Protective Role of IL-36/IL-36R Signal in Con A-Induced Acute Hepatitis
Wang, X., Liang, Y., Wang, H., Zhang, B., Soong, L., Cai, J., Yi, P., Fan, X. & Sun, J., Feb 15 2022, In: Journal of Immunology. 208, 4, p. 861-869 9 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2021
Intracellular receptor EPAC regulates von Willebrand factor secretion from endothelial cells in a PI3K-/eNOS-dependent manner during inflammation
Xiao, J., Zhang, B., Su, Z., Liu, Y., Shelite, T., Chang, Q., Qiu, Y., Bei, J., Wang, P., Bukreyev, A., Soong, L., Jin, Y., Ksiazek, T., Gaitas, A., Rossi, S. L., Zhou, J., Laposata, M., Saito, T. & Gong, B., Nov 1 2021, In: Journal of Biological Chemistry. 297, 5, 101315.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Lycium barbarum polysaccharides inhibit ischemia/reperfusion-induced myocardial injury via the Nrf2 antioxidant pathway
Liu, J. J., Zhao, G. X., He, L. L., Wang, Z., Zibrila, A. I., Niu, B. C., Gong, H. Y., Xu, J. N., Soong, L., Li, C. F. & Lu, Y., Jan 2021, In: Toxicology Reports. 8, p. 657-667 11 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Metformin Modulates T Cell Function and Alleviates Liver Injury Through Bioenergetic Regulation in Viral Hepatitis
Xu, L., Wang, X., Chen, Y., Soong, L., Chen, Y., Cai, J., Liang, Y. & Sun, J., Apr 21 2021, In: Frontiers in immunology. 12, 638575.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Mucosal vaccination induces protection against SARS-CoV-2 in the absence of detectable neutralizing antibodies
Zhong, C., Xia, H., Adam, A., Wang, B., Hajnik, R. L., Liang, Y., Rafael, G. H., Zou, J., Wang, X., Sun, J., Soong, L., Barrett, A. D. T., Weaver, S. C., Shi, P.-Y., Wang, T. & Hu, H., Dec 2021, In: npj Vaccines. 6, 1, 139.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Orientia tsutsugamushi selectively stimulates the C-type lectin receptor Mincle and type 1- skewed proinflammatory immune responses
Fisher, J., Card, G., Liang, Y., Trent, B., Rosenzweig, H. & Soong, L., Jul 2021, In: PLoS pathogens. 17, 7, e1009782.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Type I interferon promotes humoral immunity in viral vector vaccination
Zhong, C., Liu, F., Hajnik, R. J., Yao, L., Chen, K., Wang, M., Liang, Y., Sun, J., Soong, L., Hou, W. & Hu, H., Nov 2021, In: Journal of virology. 95, 22, e00925-21.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
2020
Annexin a2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and ebola virus infections
Su, Z., Chang, Q., Drelich, A., Shelite, T., Judy, B., Liu, Y., Xiao, J., Zhou, C., He, X., Jin, Y., Saito, T., Tang, S.-J., Soong, L., Wakamiya, M., Fang, X., Bukreyev, A., Ksiazek, T., Russell, W. K. & Gong, B., Jul 2020, In: PLoS neglected tropical diseases. 14, 7, p. 1-30 30 p., e0007960.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Epigenetic suppression of HIV in myeloid cells by the BRD4-selective small molecule modulator ZL0580
Alamer, E., Zhong, C., Liu, Z., Niu, Q., Long, F., Guo, L., Gelman, B. B., Soong, L., Zhou, J. & Hu, H., Jun 1 2020, In: Journal of virology. 94, 11, e01880-19.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway
Lu, Y., Li, C. F., Ping, N. N., Sun, Y. Y., Wang, Z., Zhao, G. X., Yuan, S. H., Zibrila, A. I., Soong, L. & Liu, J. J., May 1 2020, In: Journal of Biochemical and Molecular Toxicology. 34, 5, e22467.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
IL-22 hinders antiviral T cell responses and exacerbates ZIKV encephalitis in immunocompetent neonatal mice
Liang, Y., Yi, P., Ru, W., Jie, Z., Wang, H., Ghanayem, T., Wang, X., Alamer, E., Liu, J., Hu, H., Soong, L., Cai, J. & Sun, J., Aug 25 2020, In: Journal of neuroinflammation. 17, 1, 249.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Polarized lung inflammation and Tie2/angiopoietin-mediated endothelial dysfunction during severe Orientia tsutsugamushi infection
Trent, B., Liang, Y., Xing, Y., Esqueda, M., Wei, Y., Cho, N. H., Kim, H. I., Kim, Y. S., Shelite, T. R., Cai, J., Sun, J., Bouyer, D. H., Liu, J. & Soong, L., Mar 1 2020, In: PLoS neglected tropical diseases. 14, 3, p. e0007675Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Retinoic acid modulates hyperactive T cell responses and protects Vitamin A deficient mice against persistent lymphocytic choriomeningitis virus infection
Liang, Y., Yi, P., Wang, X., Zhang, B., Jie, Z., Soong, L. & Sun, J., Jun 1 2020, In: Journal of Immunology. 204, 11, p. 2984-2994 11 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
2019
Aportes científicos en el enfrentamiento a la leishmaniasis una enfermedad desatendida
Translated title of the contribution :Scientific contributions in the fight against leishmaniasis, a neglected disease Research output: Contribution to journal › Article › peer-review
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CD4+ T cell-dependent macrophage activation modulates sustained ps exposure on intracellular amastigotes of leishmania amazonensis
Wanderley, J. L. M., Deolindo, P., Carlsen, E., Portugal, A. B., DaMatta, R. A., Barcinski, M. A. & Soong, L., 2019, In: Frontiers in Cellular and Infection Microbiology. 9, APR, 105.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
IL-33 induces immunosuppressive neutrophils via a type 2 innate lymphoid cell/IL-13/STAT6 axis and protects the liver against injury in LCMV infection-induced viral hepatitis
Liang, Y., Yi, P., Yuan, D. M. K., Jie, Z., Kwota, Z., Soong, L., Cong, Y. & Sun, J., Feb 1 2019, In: Cellular and Molecular Immunology. 16, 2, p. 126-137 12 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
Immunotherapy using anti-PD-1 and anti-PD-L1 in Leishmania amazonensis-infected BALB/c mice reduce parasite load
da Fonseca-Martins, A. M., Ramos, T. D., Pratti, J. E. S., Firmino-Cruz, L., Gomes, D. C. O., Soong, L., Saraiva, E. M. & de Matos Guedes, H. L., Dec 1 2019, In: Scientific reports. 9, 1, 20275.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
2018
Developmental Defects Associated with DNA Copy Number Gain of Chromosome 2q33.1: A Case Report and Review of Literature
Gupta, A., Yo, J., Huang, G., Soong, L. & Dong, J., Mar 21 2018, In: Lab Medicine. 49, 2, p. 160-164 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Distinct susceptibility of HIV vaccine vector-induced CD4 T cells to HIV infection
Auclair, S., Liu, F., Niu, Q., Hou, W., Churchyard, G., Morgan, C., Frahm, N., Nitayaphan, S., Pitisuthithum, P., Rerks-Ngarm, S., Kimata, J. T., Soong, L., Franchini, G., Robb, M., Kim, J., Michael, N. & Hu, H., Feb 2018, In: PLoS pathogens. 14, 2, e1006888.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Imported leishmaniasis cases in Cuba (2006-2016): What have we learned
Montalvo, A. M., Fraga, J., Blanco, O., González, D., Monzote, L., Soong, L. & Capó, V., Aug 7 2018, In: Tropical Diseases, Travel Medicine and Vaccines. 4, 1, 7.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2017
CD8+T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection
Xu, G., Mendell, N. L., Liang, Y., Shelite, T., Goez-Rivillas, Y., Soong, L., Bouyer, D. H. & Walker, D. H., Jul 19 2017, In: PLoS neglected tropical diseases. 11, 7, e0005763.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Outcomes of Congenital Zika Disease Depend on Timing of Infection and Maternal-Fetal Interferon Action
Chen, J., Liang, Y., Yi, P., Xu, L., Hawkins, H., Rossi, S. L., Soong, L., Cai, J., Menon, R. & Sun, J., Nov 7 2017, In: Cell Reports. 21, 6, p. 1588-1599 12 p.Research output: Contribution to journal › Article › peer-review
Open Access75 Scopus citations -
Priming and activation of inflammasome by canarypox virus vector alvac via the CGAS/IFI16-sting-type I IFN pathway and AIM2 sensor
Liu, F., Niu, Q., Fan, X., Liu, C., Zhang, J., Wei, Z., Hou, W., Kanneganti, T. D., Robb, M. L., Kim, J. H., Michael, N. L., Sun, J., Soong, L. & Hu, H., Nov 1 2017, In: Journal of Immunology. 199, 9, p. 3293-3305 13 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Retinoic acid regulates immune responses by promoting IL-22 and modulating S100 proteins in viral hepatitis
Jie, Z., Liang, Y., Yi, P., Tang, H., Soong, L., Cong, Y., Zhang, K. & Sun, J., May 1 2017, In: Journal of Immunology. 198, 9, p. 3448-3460 13 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Splenic CD4+ T cells in progressive visceral leishmaniasis show a mixed effector-regulatory phenotype and impair macrophage effector function through inhibitory receptor expression
Medina-Colorado, A. A., Osorio, E. Y., Saldarriaga, O. A., Travi, B. L., Kong, F., Spratt, H., Soong, L. & Melby, P. C., Jan 2017, In: PloS one. 12, 1, e0169496.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
The burden of leishmaniasis in Iran, acquired from the global burden of disease during 1990-2010
Badirzadeh, A., Mohebali, M., Asadgol, Z., Soong, L., Zeinali, M., Mokhayeri, Y., Shirzadi, M. R. & Spotin, A., Sep 1 2017, In: Asian Pacific Journal of Tropical Disease. 7, 9, p. 513-518 6 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Type 1-skewed neuroinflammation and vascular damage associated with Orientia tsutsugamushi infection in mice
Soong, L., Shelite, T., Xing, Y., Kodakandla, H., Liang, Y., Trent, B., Horton, P., Smith, K. C., Zhao, Z., Sun, J., Bouyer, D. H. & Cai, J., Jul 24 2017, In: PLoS neglected tropical diseases. 11, 7, e0005765.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Viral retinopathy in experimental models of zika infection
Zhao, Z., Yang, M., Azar, S. R., Soong, L., Weaver, S. C., Sun, J., Chen, Y., Rossi, S. L. & Cai, J., Aug 2017, In: Investigative Ophthalmology and Visual Science. 58, 10, p. 4075-4085 11 p.Research output: Contribution to journal › Article › peer-review
Open Access47 Scopus citations -
2016
An Intradermal Inoculation Mouse Model for Immunological Investigations of Acute Scrub Typhus and Persistent Infection
Soong, L., Mendell, N. L., Olano, J. P., Rockx-Brouwer, D., Xu, G., Goez-Rivillas, Y., Drom, C., Shelite, T. R., Valbuena, G., Walker, D. H. & Bouyer, D. H., Aug 1 2016, In: PLoS neglected tropical diseases. 10, 8, e0004884.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
IL-33-Dependent Endothelial Activation Contributes to Apoptosis and Renal Injury in Orientia tsutsugamushi-Infected Mice
Shelite, T., Liang, Y., Wang, H., Mendell, N. L., Trent, B., Sun, J., Gong, B., Xu, G., Hu, H., Bouyer, D. H. & Soong, L., Mar 4 2016, In: PLoS neglected tropical diseases. 10, 3, e0004467.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
MTOR mediates IL-23 induction of neutrophil IL-17 and IL-22 production
Chen, F., Cao, A., Yao, S., Evans-Marin, H. L., Liu, H., Wu, W., Carlsen, E. D., Dann, S. M., Soong, L., Sun, J., Zhao, Q. & Cong, Y., May 15 2016, In: Journal of Immunology. 196, 10, p. 4390-4399 10 p.Research output: Contribution to journal › Article › peer-review
Open Access88 Scopus citations -
Sequential Dysfunction and Progressive Depletion of Candida albicans-Specific CD4 T Cell Response in HIV-1 Infection
Liu, F., Fan, X., Auclair, S., Ferguson, M., Sun, J., Soong, L., Hou, W., Redfield, R. R., Birx, D. L., Ratto-Kim, S., Robb, M. L., Kim, J. H., Michael, N. L. & Hu, H., Jun 2016, In: PLoS pathogens. 12, 6, e1005663.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
The MET Receptor Tyrosine Kinase Confers Repair of Murine Pancreatic Acinar Cells following Acute and Chronic Injury
Gaziova, I., Jackson, D., Boor, P., Carter, D., Cruz-Monserrate, Z., Elferink, C. J., Joshi, A., Kaphalia, B., Logsdon, C. D., De Castro, K. P., Soong, L., Tao, X., Qiu, S. & Elferink, L. A., Oct 2016, In: PloS one. 11, 10, 0165485.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2015
Exchange protein directly activated by cAMP modulates regulatory T-cell-mediated immunosuppression
Almahariq, M., Mei, F. C., Wang, H., Cao, A. T., Yao, S., Soong, L., Sun, J., Cong, Y., Chen, J. & Cheng, X., Jan 15 2015, In: Biochemical Journal. 465, p. 295-303 9 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations