Mahmoud Ahmed, PhD, MS

Director, Obstetrical-Fetal Pharmacology Center

  • 1906 Citations
  • 25 h-Index
1974 …2019

Research output per year

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Research Output

8 Scopus citations

An enantiomer-selective liquid chromatography-tandem mass spectrometry method for methadone and EDDP validated for use in human plasma, urine, and liver microsomes

Moody, D. E., Lin, S. N., Chang, Y., Lamm, L., Greenwald, M. K. & Ahmed, M. S., Apr 2008, In : Journal of Analytical Toxicology. 32, 3, p. 208-219 12 p.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations

A new approach to teaching biochemistry to nursing students

Ahmed, M. S., Jan 1981, In : Biochemical Education. 9, 1, p. 19-20 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

A non-denaturing gel electrophoresis system for the purification of membrane bound proteins

Cavinato, A. G., Macleod, R. M. & Ahmed, M. S., Jun 1 1988, In : Preparative Biochemistry. 18, 2, p. 205-216 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Are we optimizing gestational diabetes treatment with glyburide the pharmacologic basis for better clinical practice

Hebert, M. F., Ma, X., Naraharisetti, S. B., Krudys, K. M., Umans, J. G., Hankins, G. D. V., Caritis, S. N., Miodovnik, M., Mattison, D. R., Unadkat, J. D., Kelly, E. J., Blough, D., Cobelli, C., Ahmed, M. S., Snodgrass, W. R., Carr, D. B., Easterling, T. R. & Vicini, P., Jun 1 2009, In : Clinical Pharmacology and Therapeutics. 85, 6, p. 607-614 8 p.

Research output: Contribution to journalArticle

144 Scopus citations

Aromatase is the major enzyme metabolizing buprenorphine in human placenta

Deshmukh, S. V., Nanovskaya, T. N. & Ahmed, M. S., Sep 1 2003, In : Journal of Pharmacology and Experimental Therapeutics. 306, 3, p. 1099-1105 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Bidirectional transfer of methadone across human placenta

Nekhayeva, I. A., Nanovskaya, T. N., Deshmukh, S. V., Zharikova, O. L., Hankins, G. D. V. & Ahmed, M. S., Jan 1 2005, In : Biochemical Pharmacology. 69, 1, p. 187-197 11 p.

Research output: Contribution to journalArticle

63 Scopus citations
5 Scopus citations

Binding of cosalane - A novel highly lipophilic anti-HIV agent - To albumin and glycoprotein

Kuchimanchi, K. R., Ahmed, M. S., Johnston, T. P. & Mitra, A. K., Jan 1 2001, In : Journal of Pharmaceutical Sciences. 90, 5, p. 659-666 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Biochemical and pharmacological studies on the opiate receptors from human placenta

Ahmed, M. S., Abdelhamid, E. E. & Turner, D., 1983, In : Life Sciences. 33, SUPPL. 1, p. 207-210 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Bupropion metabolism by human placenta

Wang, X., Abdelrahman, D. R., Zharikova, O. L., Patrikeeva, S. L., Hankins, G. D. V., Ahmed, M. S. & Nanovskaya, T. N., Jun 1 2010, In : Biochemical Pharmacology. 79, 11, p. 1684-1690 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Bupropion sustained release for pregnant smokers: a randomized, placebo-controlled trial

Nanovskaya, T. N., Oncken, C., Fokina, V. M., Feinn, R. S., Clark, S. M., West, H., Jain, S. K., Ahmed, M. S. & Hankins, G. D. V., Apr 1 2017, In : American Journal of Obstetrics and Gynecology. 216, 4, p. 420.e1-420.e9

Research output: Contribution to journalArticle

12 Scopus citations
10 Scopus citations

Characterization of a cocaine binding protein in human placenta

Ahmed, M. S., Zhou, D. H., Maulik, D. & Eldefrawi, M. E., 1990, In : Life Sciences. 46, 8, p. 553-561 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

Characterization of solubilized opiate receptors from human placenta

Ahmed, M. S., Jan 1 1983, In : Molecular membrane biology. 5, 1, p. 35-47 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Correlation between the number of placental opioid receptors, mode of delivery, and maternal narcotic use

Ahmed, M. S., Schinfeld, J. S., Jones, R., Cavinato, A. G. & Baker, C., Jan 1 1986, In : Molecular membrane biology. 6, 3, p. 255-267 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Dynorphin A(1-8) in human placenta: Amino acid sequence determined by tandem mass spectrometry

Agbas, A., Ahmed, M. S., Millington, W., Cemerikic, B., Desiderio, D. M., Tseng, J. L. & Dass, C., 1995, In : Peptides. 16, 4, p. 623-627 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Effect of albumin on transplacental transfer and distribution of rosiglitazone and glyburide

Nanovskaya, T. N., Patrikeeva, S., Hemauer, S., Fokina, V., Mattison, D., Hankins, G. D. & Ahmed, M. S., Mar 3 2008, In : Journal of Maternal-Fetal and Neonatal Medicine. 21, 3, p. 197-207 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

Effect of CYP2C9 Polymorphisms on the Pharmacokinetics of Indomethacin During Pregnancy

Shah, M., Xu, M., Shah, P., Wang, X-M., Clark, S., Costantine, M., West, H. A., Nanovskaya, T., Ahmed, M., Abdel-Rahman, S., Venkataramanan, R., Caritis, S. N., Hankins, G. & Rytting, E., Jan 1 2018, (Accepted/In press) In : European Journal of Drug Metabolism and Pharmacokinetics.

Research output: Contribution to journalArticle

Effect of human serum albumin on transplacental transfer of glyburide

Nanovskaya, T. N., Nekhayeva, I., Hankins, G. D. V. & Ahmed, M. S., Aug 28 2006, In : Biochemical Pharmacology. 72, 5, p. 632-639 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

Effect of plasma proteins on buprenorphine transfer across dually perfused placental lobule

Nanovskaya, T. N., Bowen, R. S., Patrikeeva, S. L., Hankins, G. D. V. & Ahmed, M. S., Nov 9 2009, In : Journal of Maternal-Fetal and Neonatal Medicine. 22, 8, p. 646-653 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Effects of methadone use during pregnancy on human placental opioid receptors

Ahmed, M. S., Cemerikic, B., Mou, S. & Agbas, A., Jan 1 1993, In : Molecular membrane biology. 10, 2, p. 91-98 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Effects of nicotine-specific antibodies, Nic311 and Nic-IgG, on the transfer of nicotine across the human placenta

Nekhayeva, I. A., Nanovskaya, T. N., Pentel, P. R., Keyler, D. E., Hankins, G. D. V. & Ahmed, M. S., Nov 25 2005, In : Biochemical Pharmacology. 70, 11, p. 1664-1672 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Evidence for human placental kappa opiate receptor down regulation due to methadone use during pregnancy

Ahmed, M. S., Schoof, T. D., Zhou, D., Sagduyu, K. & Maulik, D., Jan 1 1990, New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. Van Ree, J. M., Mulder, A. H., Wiegant, V. M., Van Wimersma Greidanus, T. B., Van Ree, J. M., Mulder, A. H., Wiegant, V. M. & Van Wimersma Greidanus, T. B. (eds.). Elsevier Science Publishers B.V., p. 135-136 2 p. (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Fetal Drug Therapy

Rytting, E. & Ahmed, M. S., Aug 27 2013, Clinical Pharmacology During Pregnancy. Elsevier Inc., p. 55-72 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations

Glyburide metabolism by placentas of healthy and gestational diabetics

Jain, S., Zharikova, O. L., Ravindran, S., Nanovskya, T. N., Mattison, D. R., Hankins, G. D. V. & Ahmed, M. S., Mar 1 2008, In : American Journal of Perinatology. 25, 3, p. 169-174 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Human placental opioid peptides: Correlation to the route of delivery

Ahmed, M. S., Randall, L. W., Cavinato, A. G., Desiderio, D. M., Fridland, G. & Sibai, B., Jan 1 1986, In : American journal of obstetrics and gynecology. 155, 4, p. 703-706 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

Identification of dynorphin 1-8 in human placenta by mass spectrometry

Ahmed, M. S., Randall, L. W., Sibai, B., Dass, C., Fridland, G., Desiderio, D. M. & Tolun, E., May 25 1987, In : Life Sciences. 40, 21, p. 2067-2076 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Identification of glyburide metabolites formed by hepatic and placental microsomes of humans and baboons

Ravindran, S., Zharikova, O. L., Hill, R. A., Nanovskaya, T. N., Hankins, G. D. V. & Ahmed, M. S., Dec 15 2006, In : Biochemical Pharmacology. 72, 12, p. 1730-1737 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Identification of L-type calcium channels associated with kappa opioid receptors in human placenta

Cemerikic, B., Zamah, R. & Ahmed, M. S., Jan 1 1998, In : Journal of Molecular Neuroscience. 10, 3, p. 261-272 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Identification of the major human hepatic and placental enzymes responsible for the biotransformation of glyburide

Zharikova, O. L., Fokina, V. M., Nanovskaya, T. N., Hill, R. A., Mattison, D. R., Hankins, G. D. V. & Ahmed, M. S., Dec 15 2009, In : Biochemical Pharmacology. 78, 12, p. 1483-1490 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

IFPA Meeting 2012 Workshop Report II: Epigenetics and imprinting in the placenta, growth factors and villous trophoblast differentiation, role of the placenta in regulating fetal exposure to xenobiotics during pregnancy, infection and the placenta

Ahmed, M. S., Aleksunes, L. M., Boeuf, P., Chung, M. K., Daoud, G., Desoye, G., Díaz, P., Golos, T. G., Illsley, N. P., Kikuchi, K., Komatsu, R., Lao, T., Morales-Prieto, D. M., Nanovskaya, T., Nobuzane, T., Roberts, C. T., Saffery, R., Tamura, I., Tamura, K., Than, N. G. & 8 others, Tomi, M., Umbers, A., Wang, B., Weedon-Fekjaer, M. S., Yamada, S., Yamazaki, K., Yoshie, M. & Lash, G. E., Jan 1 2013, In : Placenta. 34, SUPPL, p. S6-S10

Research output: Contribution to journalArticle

6 Scopus citations

Illicit drug abuse during pregnancy: Effects of opiates and cocaine on human placenta

Ahmed, M. S., Zhou, D., Schoof, T., Spong, C., Sagduyu, K., Agbas, A. & Maulik, D., Dec 1 1990, NIDA Research Monograph Series. 105 ed. p. 278-279 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Illicit drug use during pregnancy: effects of opiates and cocaine on human placenta.

Ahmed, M., Zhou, D., Schoof, T., Spong, C., Sagduyu, K., Agbas, A. & Maulik, D., 1991, In : NIDA research monograph. 105, p. 278-279 2 p.

Research output: Contribution to journalArticle

Impact of Pregnancy History and 17-Hydroxyprogesterone Caproate on Cervical Cytokines and Matrix Metalloproteinases

Caritis, S. N., Hankins, G., Hebert, M., Haas, D. M., Ahmed, M., Simhan, H., Haneline, L. A., Harris, J., Chang, J., Famy, A. S., Yorio, P., Ren, Z., D'alton, M. E. & Venkataramanan, R., Nov 15 2017, (Accepted/In press) In : American Journal of Perinatology.

Research output: Contribution to journalArticle

1 Scopus citations

Inhibition of specific 3H-dioxolane binding to the cholinergic receptors of the rat brain by furan analogs of muscarine

Ahmed, M. S. & Sastry, B. V. R., Jan 1 1984, In : Federation Proceedings. 43, 6, p. no. 812

Research output: Contribution to journalArticle

Interleukin 1 reduces opioid binding in guinea pig brain

Ahmed, M. S., Llanos, J. Q., Dinarello, C. A. & Blatteis, C. M., Jan 1 1985, In : Peptides. 6, 6, p. 1149-1154 6 p.

Research output: Contribution to journalArticle

48 Scopus citations

Investigation of the saponin content of Enterolobium cyclocarpum

Mahran, G. H., El-Alfy, T. S., Ahmed, M. S. & Hanna, S., Jan 1 1979, In : Biochimica et Biophysica Acta. 569, 1, 1 p.

Research output: Contribution to journalArticle

Kappa opioid receptors of human placental villi modulate acetylcholine release

Ahmed, M. S., Schoof, T., Zhou, D. H. & Quarles, C., 1989, In : Life Sciences. 45, 25, p. 2383-2393 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Kinetics of glyburide metabolism by hepatic and placental microsomes of human and baboon

Zharikova, O. L., Ravindran, S., Nanovskaya, T. N., Hill, R. A., Hankins, G. D. V. & Ahmed, M. S., Jun 15 2007, In : Biochemical Pharmacology. 73, 12, p. 2012-2019 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

M281, an anti-FcRn antibody, inhibits IgG transfer in a human ex vivo placental perfusion model

Roy, S., Nanovskaya, T., Patrikeeva, S., Cochran, E., Parge, V., Guess, J., Schaeck, J., Choudhury, A., Ahmed, M. & Ling, L. E., May 1 2019, In : American journal of obstetrics and gynecology. 220, 5, p. 498.e1-498.e9

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Macro- and micromorphology of the flowers of Plumeria rubra L. and Plumeria rubra L. var. alba

Mahran, G. H., Abdel Wahab, S. M. & Ahmed, M. S., Jan 1 1974, In : Egyptian Journal of Pharmaceutical Sciences. 15, 1, p. 91-112 22 p.

Research output: Contribution to journalArticle

Macro- and micromorphology of the roots and stems of Plumeria rubra L. and Plumeria rubra L. Var. alba

Mahran, G. H., Abdel Wahab, S. M. & Ahmed, M. S., Jan 1 1974, In : Egyptian Journal of Pharmaceutical Sciences. 15, 1, p. 113-126 14 p.

Research output: Contribution to journalArticle

Maternal Cigarette Smoking Depresses Placental Amino Acid Transport, Which May Lower the Birthweight of Infants

SASTRY, B. V. RAMA., JANSON, V. E., AHMED, M., KNOTS, J. & SCHINFELD, J. S., Jun 1989, In : Annals of the New York Academy of Sciences. 562, 1, p. 367-369 3 p.

Research output: Contribution to journalArticle

8 Scopus citations

Metabolism and disposition of bupropion in pregnant baboons (Papio cynocephalus)

Rytting, E., Wang, X., Vernikovskaya, D. I., Zhan, Y., Bauer, C., Abdel-Rahman, S. M., Ahmed, M. S. & Nanovskaya, T. N., Oct 1 2014, In : Drug Metabolism and Disposition. 42, 10, p. 1773-1779 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Metabolism of 17-alpha-hydroxyprogesterone caproate by human placental mitochondria

Fokina, V. M., Zharikova, O. L., Hankins, G. D. V., Ahmed, M. S. & Nanovskaya, T. N., Mar 1 2012, In : Reproductive Sciences. 19, 3, p. 290-297 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Metabolism of 17α-hydroxyprogesterone caproate by hepatic and placental microsomes of human and baboons

Yan, R., Nanovskaya, T. N., Zharikova, O. L., Mattison, D. R., Hankins, G. D. V. & Ahmed, M. S., May 1 2008, In : Biochemical Pharmacology. 75, 9, p. 1848-1857 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Metabolism of bupropion by baboon hepatic and placental microsomes

Wang, X., Abdelrahman, D. R., Fokina, V. M., Hankins, G. D. V., Ahmed, M. S. & Nanovskaya, T. N., Aug 1 2011, In : Biochemical Pharmacology. 82, 3, p. 295-303 9 p.

Research output: Contribution to journalArticle

10 Scopus citations