• 1821 Citations
  • 25 h-Index
1974 …2019
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Research Output 1974 2019

  • 1821 Citations
  • 25 h-Index
  • 96 Article
  • 3 Conference contribution
  • 2 Chapter
  • 1 Review article
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Article
2019

M281, an anti-FcRn antibody, inhibits IgG transfer in a human ex vivo placental perfusion model

Roy, S., Nanovskaya, T., Patrikeeva, S., Cochran, E., Parge, V., Guess, J., Schaeck, J., Choudhury, A., Ahmed, M. & Ling, L. E., May 1 2019, In : American journal of obstetrics and gynecology. 220, 5, p. 498.e1-498.e9

Research output: Contribution to journalArticle

Open Access
Anti-Idiotypic Antibodies
Perfusion
Immunoglobulin G
Trophoblasts
Fetus
2018
Antipyrine
High performance liquid chromatography
Paclitaxel
Photodiodes
Perfusion

Effect of CYP2C9 Polymorphisms on the Pharmacokinetics of Indomethacin During Pregnancy

Shah, M., Xu, M., Shah, P., Wang, X-M., Clark, S., Costantine, M., West, H. A., Nanovskaya, T., Ahmed, M., Abdel-Rahman, S., Venkataramanan, R., Caritis, S. N., Hankins, G. & Rytting, E., Jan 1 2018, (Accepted/In press) In : European Journal of Drug Metabolism and Pharmacokinetics.

Research output: Contribution to journalArticle

Indomethacin
Pharmacokinetics
Pregnancy
Genotype
Tocolytic Agents
2 Citations (Scopus)

Prednisone Pharmacokinetics During Pregnancy and Lactation

Ryu, R. J., Easterling, T. R., Caritis, S. N., Venkataramanan, R., Umans, J. G., Ahmed, M., Clark, S., Kantrowitz-Gordon, I., Hays, K., Bennett, B., Honaker, M. T., Thummel, K. E., Shen, D. D. & Hebert, M. F., Jan 1 2018, (Accepted/In press) In : Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Prednisone
Lactation
Prednisolone
Pharmacokinetics
Pregnancy
1 Citation (Scopus)

Role of the efflux transporters BCRP and MRP1 in human placental bio-disposition of pravastatin

Afrouzian, M., Al Lahham, R., Patrikeeva, S., Xu, M., Fokina, V., Fischer, W. G., Abdel-Rahman, S., Costantine, M., Ahmed, M. & Nanovskaya, T., Oct 1 2018, In : Biochemical Pharmacology. 156, p. 467-478 12 p.

Research output: Contribution to journalArticle

Pravastatin
Placenta
Trophoblasts
Membranes
Adenosine Triphosphate
2017
9 Citations (Scopus)
Bupropion
Placebos
Smoking Cessation
Pregnancy
Substance Withdrawal Syndrome

Impact of Pregnancy History and 17-Hydroxyprogesterone Caproate on Cervical Cytokines and Matrix Metalloproteinases

Caritis, S. N., Hankins, G., Hebert, M., Haas, D. M., Ahmed, M., Simhan, H., Haneline, L. A., Harris, J., Chang, J., Famy, A. S., Yorio, P., Ren, Z., D'alton, M. E. & Venkataramanan, R., Nov 15 2017, (Accepted/In press) In : American Journal of Perinatology.

Research output: Contribution to journalArticle

17-alpha-Hydroxyprogesterone
Reproductive History
Matrix Metalloproteinases
Cytokines
Premature Birth
Bupropion
Biotransformation
Alcohol Oxidoreductases
Enzymes
Placenta
2016
9 Citations (Scopus)
Bupropion
Umbilical Cord
Amniotic Fluid
Pregnancy
Pharmaceutical Preparations
4 Citations (Scopus)

Pharmacokinetics of bupropion and its pharmacologically active metabolites in pregnancy

Fokina, V., Xu, M., Rytting, E., Abdel-Rahman, S., West, H., Oncken, C., Clark, S., Ahmed, M., Hankins, G. & Nanovskaya, T., 2016, In : Drug Metabolism and Disposition. 44, 11, p. 1832-1838 7 p.

Research output: Contribution to journalArticle

Bupropion
Pharmacokinetics
Pregnancy
Smoking Cessation
Alleles
4 Citations (Scopus)

Quantitative determination of pravastatin and its metabolite 3α-hydroxy pravastatin in plasma and urine of pregnant patients by LC-MS/MS

Zhang, X., Vernikovskaya, D. I., Wang, X-M., Nanovskaya, T., Costantine, M., Hankins, G. & Ahmed, M., Apr 1 2016, In : Biomedical Chromatography. 30, 4, p. 548-554 7 p.

Research output: Contribution to journalArticle

Pravastatin
Metabolites
Urine
Plasmas
Liquid-Liquid Extraction
2015
34 Citations (Scopus)

Proceedings from the American College of Rheumatology Reproductive Health Summit: The management of fertility, pregnancy, and lactation in women with autoimmune and systemic inflammatory diseases

Kavanaugh, A., Cush, J. J., Ahmed, M., Bermas, B. L., Chakravarty, E., Chambers, C., Clowse, M., Curtis, J. R., Dao, K., Hankins, G., Koren, G., Kim, S. C., Lapteva, L., Mahadevan, U., Moore, T., Nolan, M., Ren, Z., Sammaritano, L. R., Seymour, S. & Weisman, M. H., Mar 1 2015, In : Arthritis Care and Research. 67, 3, p. 313-325 13 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Quantitative determination of metformin, glyburide and its metabolites in plasma and urine of pregnant patients by LC-MS/MS

Zhang, X., Wang, X-M., Vernikovskaya, D. I., Fokina, V., Nanovskaya, T., Hankins, G. & Ahmed, M., Apr 1 2015, In : Biomedical Chromatography. 29, 4, p. 560-569 10 p.

Research output: Contribution to journalArticle

Metabolites
Urine
Plasmas
Glyburide
Metformin
62 Citations (Scopus)

Safety and pharmacokinetics of pravastatin used for the prevention of preeclampsia in high-risk pregnant women: A pilot randomized controlled trial

Costantine, M., Cleary, K., Hebert, M. F., Ahmed, M., Brown, L. M., Ren, Z., Easterling, T. R., Haas, D. M., Haneline, L. S., Caritis, S. N., Venkataramanan, R., West, H., D'Alton, M. & Hankins, G., Sep 30 2015, (Accepted/In press) In : American Journal of Obstetrics and Gynecology.

Research output: Contribution to journalArticle

Pravastatin
Pre-Eclampsia
Pregnant Women
Randomized Controlled Trials
Pharmacokinetics
2014
6 Citations (Scopus)

Metabolism and disposition of bupropion in pregnant baboons (Papio cynocephalus)

Rytting, E., Wang, X-M., Vernikovskaya, D. I., Zhan, Y., Bauer, C., Abdel-Rahman, S. M., Ahmed, M. & Nanovskaya, T., Oct 1 2014, In : Drug Metabolism and Disposition. 42, 10, p. 1773-1779 7 p.

Research output: Contribution to journalArticle

Papio cynocephalus
Bupropion
Papio
Postpartum Period
Pregnancy
12 Citations (Scopus)

Pharmacokinetics of indomethacin in pregnancy

Rytting, E., Nanovskaya, T., Wang, X-M., Vernikovskaya, D. I., Clark, S., Cochran, M., Abdel-Rahman, S. M., Venkataramanan, R., Caritis, S. N., Hankins, G. & Ahmed, M., 2014, In : Clinical Pharmacokinetics. 53, 6, p. 545-551 7 p.

Research output: Contribution to journalArticle

Indomethacin
Pharmacokinetics
Pregnancy
Premature Obstetric Labor
Fetal Blood
5 Citations (Scopus)
Papio
Solid Phase Extraction
Plasmas
Teicoplanin
Pregnancy
2013
8 Citations (Scopus)
Liquid chromatography
Indomethacin
Liquid Chromatography
Mass spectrometry
Mass Spectrometry
5 Citations (Scopus)

IFPA Meeting 2012 Workshop Report II: Epigenetics and imprinting in the placenta, growth factors and villous trophoblast differentiation, role of the placenta in regulating fetal exposure to xenobiotics during pregnancy, infection and the placenta

Ahmed, M., Aleksunes, L. M., Boeuf, P., Chung, M. K., Daoud, G., Desoye, G., Díaz, P., Golos, T. G., Illsley, N. P., Kikuchi, K., Komatsu, R., Lao, T., Morales-Prieto, D. M., Nanovskaya, T., Nobuzane, T., Roberts, C. T., Saffery, R., Tamura, I., Tamura, K., Than, N. G. & 8 othersTomi, M., Umbers, A., Wang, B., Weedon-Fekjaer, M. S., Yamada, S., Yamazaki, K., Yoshie, M. & Lash, G. E., 2013, In : Placenta. 34, SUPPL

Research output: Contribution to journalArticle

Trophoblasts
Xenobiotics
Epigenomics
Placenta
Education
3 Citations (Scopus)
Famotidine
Plasma (human)
Umbilical Cord
High performance liquid chromatography
Mass spectrometry
34 Citations (Scopus)

Transplacental transfer and distribution of pravastatin

Nanovskaya, T., Patrikeeva, S. L., Paul, J., Costantine, M., Hankins, G. & Ahmed, M., Oct 2013, In : American Journal of Obstetrics and Gynecology. 209, 4

Research output: Contribution to journalArticle

Pravastatin
Mothers
Antipyrine
Paclitaxel
Isotopes
2012
5 Citations (Scopus)

Metabolism of 17-alpha-hydroxyprogesterone caproate by human placental mitochondria

Fokina, V., Zharikova, O. L., Hankins, G., Ahmed, M. & Nanovskaya, T., Mar 2012, In : Reproductive Sciences. 19, 3, p. 290-297 8 p.

Research output: Contribution to journalArticle

Mitochondria
Perfusion
Biotransformation
Microsomes
Subcellular Fractions
17 Citations (Scopus)
Bupropion
Umbilical Cord
High performance liquid chromatography
Metabolites
Tandem Mass Spectrometry
9 Citations (Scopus)

Transplacental transfer of oseltamivir carboxylate

Nanovskaya, T., Patrikeeva, S., Zhan, Y., Hankins, G. & Ahmed, M., Nov 2012, In : Journal of Maternal-Fetal and Neonatal Medicine. 25, 11, p. 2312-2315 4 p.

Research output: Contribution to journalArticle

Mothers
Fetus
Perfusion
Isotopes
Placenta
11 Citations (Scopus)

Transplacental transfer of vancomycin and telavancin

Nanovskaya, T., Patrikeeva, S., Zhan, Y., Fokina, V., Hankins, G. & Ahmed, M., Oct 2012, In : American Journal of Obstetrics and Gynecology. 207, 4

Research output: Contribution to journalArticle

Vancomycin
Mothers
Radioisotopes
Spectrum Analysis
Perfusion
2011
10 Citations (Scopus)

Metabolism of bupropion by baboon hepatic and placental microsomes

Wang, X-M., Abdelrahman, D. R., Fokina, V., Hankins, G., Ahmed, M. & Nanovskaya, T., Aug 1 2011, In : Biochemical Pharmacology. 82, 3, p. 295-303 9 p.

Research output: Contribution to journalArticle

Bupropion
Papio
Microsomes
Metabolism
Liver
6 Citations (Scopus)

Pharmacokinetics of metronidazole in pregnant patients with bacterial vaginosis

Wang, X., Nanovskaya, T., Zhan, Y., Abdel-Rahman, S. M., Jasek, M., Hankins, G. & Ahmed, M., Mar 2011, In : Journal of Maternal-Fetal and Neonatal Medicine. 24, 3, p. 444-448 5 p.

Research output: Contribution to journalArticle

Bacterial Vaginosis
Metronidazole
Pharmacokinetics
Pregnancy
Area Under Curve
15 Citations (Scopus)

Transplacental transfer and metabolism of buprenorphine in preterm human placenta

Fokina, V., Patrikeeva, S. L., Zharikova, O. L., Nanovskaya, T., Hankins, G. & Ahmed, M., 2011, In : American Journal of Perinatology. 28, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

Buprenorphine
Placenta
Microsomes
Third Pregnancy Trimester
Pregnancy
2010
23 Citations (Scopus)

Bupropion metabolism by human placenta

Wang, X-M., Abdelrahman, D. R., Zharikova, O. L., Patrikeeva, S. L., Hankins, G., Ahmed, M. & Nanovskaya, T., Jun 2010, In : Biochemical Pharmacology. 79, 11, p. 1684-1690 7 p.

Research output: Contribution to journalArticle

Bupropion
Metabolism
Placenta
Pregnancy
Enzymes
52 Citations (Scopus)

Modulation of human placental P-glycoprotein expression and activity by MDR1 gene polymorphisms

Hemauer, S. J., Nanovskaya, T., Abdel-Rahman, S., Patrikeeva, S. L., Hankins, G. & Ahmed, M., Mar 15 2010, In : Biochemical Pharmacology. 79, 6, p. 921-925 5 p.

Research output: Contribution to journalArticle

P-Glycoprotein
Polymorphism
Placenta
Genes
Modulation
63 Citations (Scopus)
rosiglitazone
Membrane Transport Proteins
P-Glycoprotein
P-Glycoproteins
Breast Neoplasms
17 Citations (Scopus)

Role of transporter-mediated efflux in the placental biodisposition of bupropion and its metabolite, OH-bupropion

Hemauer, S. J., Patrikeeva, S. L., Wang, X-M., Abdelrahman, D. R., Hankins, G., Ahmed, M. & Nanovskaya, T., Oct 2010, In : Biochemical Pharmacology. 80, 7, p. 1080-1086 7 p.

Research output: Contribution to journalArticle

Bupropion
Metabolites
Smoking Cessation
Metabolism
Placenta
25 Citations (Scopus)

Transplacental transfer and metabolism of bupropion

Earhart, A. D., Patrikeeva, S., Wang, X-M., Reda Abdelrahman, D., Hankins, G., Ahmed, M. & Nanovskaya, T., May 2010, In : Journal of Maternal-Fetal and Neonatal Medicine. 23, 5, p. 409-416 8 p.

Research output: Contribution to journalArticle

Bupropion
Mothers
Smoking Cessation
Pregnancy
Antipyrine
2009
137 Citations (Scopus)

Are we optimizing gestational diabetes treatment with glyburide the pharmacologic basis for better clinical practice

Hebert, M. F., Ma, X., Naraharisetti, S. B., Krudys, K. M., Umans, J. G., Hankins, G., Caritis, S. N., Miodovnik, M., Mattison, D. R., Unadkat, J. D., Kelly, E. J., Blough, D., Cobelli, C., Ahmed, M., Snodgrass, W. R., Carr, D. B., Easterling, T. R. & Vicini, P., Jun 2009, In : Clinical Pharmacology and Therapeutics. 85, 6, p. 607-614 8 p.

Research output: Contribution to journalArticle

Gestational Diabetes
Glyburide
Pregnant Women
Insulin Resistance
Meals
4 Citations (Scopus)

Effect of plasma proteins on buprenorphine transfer across dually perfused placental lobule

Nanovskaya, T., Bowen, R. S., Patrikeeva, S. L., Hankins, G. & Ahmed, M., 2009, In : Journal of Maternal-Fetal and Neonatal Medicine. 22, 8, p. 646-653 8 p.

Research output: Contribution to journalArticle

Buprenorphine
Blood Proteins
Mothers
Perfusion
Antipyrine
37 Citations (Scopus)

Identification of the major human hepatic and placental enzymes responsible for the biotransformation of glyburide

Zharikova, O. L., Fokina, V., Nanovskaya, T., Hill, R. A., Mattison, D. R., Hankins, G. & Ahmed, M., Dec 15 2009, In : Biochemical Pharmacology. 78, 12, p. 1483-1490 8 p.

Research output: Contribution to journalArticle

Forensic Anthropology
Glyburide
Biotransformation
Metabolites
Liver
29 Citations (Scopus)

Opiates inhibit paclitaxel uptake by P-glycoprotein in preparations of human placental inside-out vesicles

Hemauer, S. J., Patrikeeva, S. L., Nanovskaya, T., Hankins, G. & Ahmed, M., Nov 1 2009, In : Biochemical Pharmacology. 78, 9, p. 1272-1278 7 p.

Research output: Contribution to journalArticle

Opiate Alkaloids
Buprenorphine
Methadone
P-Glycoprotein
Paclitaxel
3 Citations (Scopus)

Pharmacotherapy and pregnancy: Highlights from the first International Conference for Individualized Pharmacotherapy in Pregnancy.

Haas, D. M., Renbarger, J. L., Denne, S., Ahmed, M., Easterling, T., Feibus, K., Meslin, E. M., Koren, G., Zajicek, A., Snodgrass, W. R. & Flockhart, D. A., Feb 2009, In : Clinical and Translational Science. 2, 1, p. 11-14 4 p.

Research output: Contribution to journalArticle

Drug therapy
International cooperation
Antidepressive Agents
2008
26 Citations (Scopus)

An enantiomer-selective liquid chromatography-tandem mass spectrometry method for methadone and EDDP validated for use in human plasma, urine, and liver microsomes

Moody, D. E., Lin, S. N., Chang, Y., Lamm, L., Greenwald, M. K. & Ahmed, M., Apr 2008, In : Journal of Analytical Toxicology. 32, 3, p. 208-219 12 p.

Research output: Contribution to journalArticle

Plasma (human)
Enantiomers
Methadone
Liquid chromatography
Liver Microsomes
29 Citations (Scopus)

Effect of albumin on transplacental transfer and distribution of rosiglitazone and glyburide

Nanovskaya, T., Patrikeeva, S., Hemauer, S., Fokina, V., Mattison, D., Hankins, G. & Ahmed, M., 2008, In : Journal of Maternal-Fetal and Neonatal Medicine. 21, 3, p. 197-207 11 p.

Research output: Contribution to journalArticle

rosiglitazone
Glyburide
Albumins
Serum Albumin
Mothers
7 Citations (Scopus)

Glyburide metabolism by placentas of healthy and gestational diabetics

Jain, S., Zharikova, O. L., Ravindran, S., Nanovskya, T. N., Mattison, D. R., Hankins, G. & Ahmed, M., Mar 2008, In : American Journal of Perinatology. 25, 3, p. 169-174 6 p.

Research output: Contribution to journalArticle

Glyburide
Placenta
Diabetic Diet
Diet
Pregnancy
15 Citations (Scopus)

Metabolism of 17α-hydroxyprogesterone caproate by hepatic and placental microsomes of human and baboons

Yan, R., Nanovskaya, T., Zharikova, O. L., Mattison, D. R., Hankins, G. & Ahmed, M., May 1 2008, In : Biochemical Pharmacology. 75, 9, p. 1848-1857 10 p.

Research output: Contribution to journalArticle

17-alpha-Hydroxyprogesterone
Papio
Microsomes
Metabolism
Metabolites
13 Citations (Scopus)
Acetylesterase
17-alpha-Hydroxyprogesterone
Butyrylthiocholine
Esterases
Hydrolysis
45 Citations (Scopus)
Methadone
Placenta
P-Glycoprotein
Isotopes
Antipyrine
19 Citations (Scopus)

Transplacental transfer and metabolism of 17-α-hydroxyprogesterone caproate

Hemauer, S. J., Yan, R., Patrikeeva, S. L., Mattison, D. R., Hankins, G., Ahmed, M. & Nanovskaya, T., Aug 2008, In : American Journal of Obstetrics and Gynecology. 199, 2

Research output: Contribution to journalArticle

17-alpha-Hydroxyprogesterone
Mothers
Progesterone
Fetus
Perfusion
2007
27 Citations (Scopus)

Kinetics of glyburide metabolism by hepatic and placental microsomes of human and baboon

Zharikova, O. L., Ravindran, S., Nanovskaya, T., Hill, R. A., Hankins, G. & Ahmed, M., Jun 15 2007, In : Biochemical Pharmacology. 73, 12, p. 2012-2019 8 p.

Research output: Contribution to journalArticle

Enzyme kinetics
Papio
Glyburide
Microsomes
Metabolism
13 Citations (Scopus)

The effect of opiates on the activity of human placental aromatase/CYP19

Zharikova, O. L., Deshmukh, S. V., Kumar, M., Vargas, R., Nanovskaya, T., Hankins, G. & Ahmed, M., Jan 15 2007, In : Biochemical Pharmacology. 73, 2, p. 279-286 8 p.

Research output: Contribution to journalArticle

Opiate Alkaloids
Aromatase
Human Activities
Methadyl Acetate
Pentazocine
2006
52 Citations (Scopus)

Effect of human serum albumin on transplacental transfer of glyburide

Nanovskaya, T., Nekhayeva, I., Hankins, G. & Ahmed, M., Aug 28 2006, In : Biochemical Pharmacology. 72, 5, p. 632-639 8 p.

Research output: Contribution to journalArticle

Glyburide
Serum Albumin
Placenta
Antipyrine
Gestational Diabetes
32 Citations (Scopus)

Identification of glyburide metabolites formed by hepatic and placental microsomes of humans and baboons

Ravindran, S., Zharikova, O. L., Hill, R. A., Nanovskaya, T., Hankins, G. & Ahmed, M., Dec 15 2006, In : Biochemical Pharmacology. 72, 12, p. 1730-1737 8 p.

Research output: Contribution to journalArticle

Papio
Glyburide
Metabolites
Microsomes
Liver
14 Citations (Scopus)

Methadone metabolism by early gestational age placentas

Hieronymus, T. L., Nanovskaya, T., Deshmukh, S. V., Vargas, R., Hankins, G. & Ahmed, M., Jul 2006, In : American Journal of Perinatology. 23, 5, p. 287-294 8 p.

Research output: Contribution to journalArticle

Methadone
Placenta
Gestational Age
Aromatase
Enzymes