Mariano Garcia-Blanco, MD, PhD

Chair

  • 10294 Citations
  • 53 h-Index
1975 …2020

Research output per year

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Research Output

2008

Quantification of microRNAs, splicing isoforms, and homologous mRNAs with the invader assay

Eis, P. S. & Garcia-Blanco, M., 2008, Methods in Molecular Biology. Humana Press, Vol. 488. p. 279-318 40 p. (Methods in Molecular Biology; vol. 488).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2009

Correction of tau mis-splicing caused by FTDP-17 MAPT mutations by spliceosome-mediated RNA trans-splicing

Rodriguez-Martin, T., Anthony, K., Garcia-Blanco, M. A., Mansfield, S. G., Anderton, B. H. & Gallo, J. M., Aug 20 2009, In : Human Molecular Genetics. 18, 17, p. 3266-3273 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Discovery of insect and human dengue virus host factors

Sessions, O. M., Barrows, N. J., Souza-Neto, J. A., Robinson, T. J., Hershey, C. L., Rodgers, M. A., Ramirez, J. L., Dimopoulos, G., Yang, P. L., Pearson, J. L. & Garcia-Blanco, M. A., Apr 23 2009, In : Nature. 458, 7241, p. 1047-1050 4 p.

Research output: Contribution to journalArticle

278 Scopus citations

Editorial: Biotechnology and Puerto Rico: Promises that must be kept

García-Blanco, M. A., Oct 26 2009, In : Puerto Rico health sciences journal. 28, 3, p. 217-218 2 p.

Research output: Contribution to journalEditorial

Shedding UV Light on Alternative Splicing

Marengo, M. S. & Garcia-Blanco, M. A., May 15 2009, In : Cell. 137, 4, p. 600-602 3 p.

Research output: Contribution to journalShort survey

2 Scopus citations

Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs

Miller, H. B., Saunders, K. O., Tomaras, G. D. & Garcia-Blanco, M. A., May 27 2009, In : PloS one. 4, 5, e5710.

Research output: Contribution to journalArticle

13 Scopus citations
21 Scopus citations

The polypyrimidine tract-binding protein is required for efficient dengue virus propagation and associates with the viral replication machinery

Anwar, A., Leong, K. M., Ng, M. L., Chu, J. J. H. & Garcia-Blanco, M. A., Jun 19 2009, In : Journal of Biological Chemistry. 284, 25, p. 17021-17029 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

TIA nuclear proteins regulate the alternate splicing of lysyl hydroxylase 2

Yeowell, H. N., Walker, L. C., Mauger, D. M., Seth, P. & Garcia-Blanco, M. A., Jun 1 2009, In : Journal of Investigative Dermatology. 129, 6, p. 1402-1411 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Trans-splicing into highly abundant albumin transcripts for production of therapeutic proteins in vivo

Wang, J., Mansfield, G. S., Cote, C. A., Jiang, P. D., Weng, K., Amar, M. J. A., Brewer, B. H., Remaley, A. T., McGarrity, G. J., Garcia-Blanco, M. A. & Puttaraju, M., Jan 1 2009, In : Molecular Therapy. 17, 2, p. 343-351 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
2010

Alternative splicing in multiple sclerosis and other autoimmune diseases

Evsyukova, I., Somarelli, J. A., Gregory, S. G. & Garcia-Blanco, M. A., Jan 1 2010, In : RNA Biology. 7, 4, p. 462-473 12 p.

Research output: Contribution to journalReview article

32 Scopus citations

Factors affecting reproducibility between genome-scale siRNA-based screens

Barrows, N. J., Le Sommer, C., Garcia-Blanco, M. A. & Pearson, J. L., Aug 2010, In : Journal of Biomolecular Screening. 15, 7, p. 735-747 13 p.

Research output: Contribution to journalArticle

35 Scopus citations

SplicerAV: A tool for mining microarray expression data for changes in RNA processing

Robinson, T. J., Dinan, M. A., Dewhirst, M., Garcia-Blanco, M. A. & Pearson, J. L., Feb 25 2010, In : BMC bioinformatics. 11, 108.

Research output: Contribution to journalArticle

13 Scopus citations
2011

A functional alternative splicing mutation in human tryptophan hydroxylase-2

Zhang, X., Nicholls, P. J., Laje, G., Sotnikova, T. D., Gainetdinov, R. R., Albert, P. R., Rajkowska, G., Stockmeier, C. A., Speer, M. C., Steffens, D. C., Austin, M. C., McMahon, F. J., Krishnan, K. R. R., Garcia-Blanco, M. A. & Caron, M. G., Dec 1 2011, In : Molecular Psychiatry. 16, 12, p. 1169-1176 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Circulating tumor cells from patients with advanced prostate and breast cancer display both epithelial and mesenchymal markers

Armstrong, A. J., Marengo, M. S., Oltean, S., Kemeny, G., Bitting, R. L., Turnbull, J. D., Herold, C. I., Marcom, P. K., George, D. J. & Garcia-Blanco, M. A., Aug 1 2011, In : Molecular Cancer Research. 9, 8, p. 997-1007 11 p.

Research output: Contribution to journalArticle

421 Scopus citations

Epithelial-mesenchymal transition in prostate cancer: Providing new targets for therapy

Armstrong, A. J., Freedland, S. J. & Garcia-Blanco, M., Mar 1 2011, In : Asian Journal of Andrology. 13, 2, p. 179-180 2 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing

Miller, H. B., Robinson, T. J., Gordân, R., Hartemink, A. J. & Garcia-Blanco, M. A., Apr 1 2011, In : RNA. 17, 4, p. 665-674 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Quantitative mass spectrometry of DENV-2 RNA-interacting proteins reveals that the DEAD-box RNA helicase DDX6 binds the DB1 and DB2 3′ UTR structures

Ward, A. M., Bidet, K., Yinglin, A., Ler, S. G., Hogue, K., Blackstock, W., Gunaratne, J. & Garcia-Blanco, M. A., Jan 1 2011, In : RNA Biology. 8, 6

Research output: Contribution to journalArticle

109 Scopus citations

The kinase inhibitor sfv785 dislocates dengue virus envelope protein from the replication complex and blocks virus assembly

Anwar, A., Hosoya, T., Leong, K. M., Onogi, H., Okuno, Y., Hiramatsu, T., Koyama, H., Suzuki, M., Hagiwara, M. & Garcia-Blanco, M. A., 2011, In : PloS one. 6, 8, e23246.

Research output: Contribution to journalArticle

26 Scopus citations
2012

G Protein-Coupled Receptor Kinase 2 Promotes Flaviviridae Entry and Replication

Le Sommer, C., Barrows, N. J., Bradrick, S. S., Pearson, J. L. & Garcia-Blanco, M. A., Sep 2012, In : PLoS neglected tropical diseases. 6, 9, e1820.

Research output: Contribution to journalArticle

48 Scopus citations

SplicerEX: A tool for the automated detection and classification of mRNA changes from conventional and splice-sensitive microarray expression data

Robinson, T. J., Forte, E., Salinas, R. E., Puri, S., Marengo, M., Garcia-Blanco, M. A. & Luftig, M. A., Aug 1 2012, In : RNA. 18, 8, p. 1435-1445 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2013

Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6

Evsyukova, I., Bradrick, S. S., Gregory, S. G. & Garcia-Blanco, M. A., Jan 1 2013, In : RNA. 19, 1, p. 103-115 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

Development of a method to isolate circulating tumor cells using mesenchymal-based capture

Bitting, R. L., Boominathan, R., Rao, C., Kemeny, G., Foulk, B., Garcia-Blanco, M. A., Connelly, M. & Armstrong, A. J., Dec 1 2013, In : Methods. 64, 2, p. 129-136 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Epstein-barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency

Homa, N. J., Salinas, R., Forte, E., Robinson, T. J., Garcia-Blanco, M. A. & Luftig, M. A., 2013, In : Journal of virology. 87, 22, p. 12291-12301 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Fluorescence-based alternative splicing reporters for the study of epithelial plasticity in vivo

Somarelli, J. A., Schaeffer, D., Bosma, R., Bonano, V. I., Sohn, J. W., Kemeny, G., Ettyreddy, A. & Garcia-Blanco, M. A., Jan 2013, In : RNA. 19, 1, p. 116-127 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication

Coiras, M., Montes, M., Montanuy, I., López-Huertas, M. R., Mateos, E., Le Sommer, C., Garcia-Blanco, M. A., Hernández-Munain, C., Alcamí, J. & Suñé, C., Oct 28 2013, In : Retrovirology. 10, 1, 124.

Research output: Contribution to journalArticle

9 Scopus citations
2014

A "microRNA-like" small RNA expressed by Dengue virus?

Skalsky, R. L., Olson, K. E., Blair, C. D., Garcia-Blanco, M. A. & Cullen, B. R., Jun 10 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 23, p. E2359

Research output: Contribution to journalLetter

17 Scopus citations

Biologic and clinical significance of androgen receptor variants in castration resistant prostate cancer

Ware, K. E., Garcia-Blanco, M. A., Armstrong, A. J. & Dehm, S. M., Aug 2014, In : Endocrine-Related Cancer. 21, 4, p. T87-T103

Research output: Contribution to journalReview article

87 Scopus citations

Cellular migration and invasion uncoupled: Increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition

Schaeffer, D., Somarelli, J. A., Hanna, G., Palmer, G. M. & Garcia-Blanco, M. A., 2014, In : Molecular and cellular biology. 34, 18, p. 3486-3499 14 p.

Research output: Contribution to journalArticle

38 Scopus citations

Flaviviral RNAs: Weapons and targets in the war between virus and host

Bidet, K. & Garcia-Blanco, M. A., Sep 1 2014, In : Biochemical Journal. 462, 2, p. 215-230 16 p.

Research output: Contribution to journalReview article

42 Scopus citations

Functional Genomics Approach for the Identification of Human Host Factors Supporting Dengue Viral Propagation

Barrows, N. J., Jamison, S. F., Bradrick, S. S., Le Sommer, C., Kim, S. Y., Pearson, J. & Garcia-Blanco, M. A., Jan 1 2014, In : Methods in Molecular Biology. 1138, p. 285-299 15 p.

Research output: Contribution to journalArticle

6 Scopus citations
125 Scopus citations

Identification of dengue RNA binding proteins using RNA chromatography and quantitative mass spectrometry

Ward, A. M., Gunaratne, J. & Garcia-Blanco, M. A., Jan 1 2014, In : Methods in Molecular Biology. 1138, p. 253-270 18 p.

Research output: Contribution to journalArticle

10 Scopus citations

Replication of many human viruses is refractory to inhibition by endogenous cellular MicroRNAs

Bogerd, H. P., Skalsky, R. L., Kennedy, E. M., Furuse, Y., Whisnant, A. W., Flores, O., Schultz, K. L. W., Putnam, N., Barrows, N. J., Sherry, B., Scholle, F., Garcia-Blanco, M. A., Griffin, D. E. & Cullen, B. R., Jul 2014, In : Journal of virology. 88, 14, p. 8065-8076 12 p.

Research output: Contribution to journalArticle

99 Scopus citations

Targeting host factors to treat West Nile and dengue viral infections

Krishnan, M. N. & Garcia-Blanco, M. A., Feb 10 2014, In : Viruses. 6, 2, p. 683-708 26 p.

Research output: Contribution to journalReview article

43 Scopus citations

The interface between dengue virus and the human host

Barrows, N. J., Bradrick, S. S., Bidet, K., Anwar, A., Ward, A. M., Jamison, S. F., Levitt, B., Le Sommer, C. & Garcia-Blanco, M. A., Aug 29 2014, Dengue and Dengue Hemorrhagic Fever: Second Edition. CABI International, p. 406-424 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

The role of epithelial plasticity in prostate cancer dissemination and treatment resistance

Bitting, R. L., Schaeffer, D., Somarelli, J. A., Garcia-Blanco, M. A. & Armstrong, A. J., Sep 2014, In : Cancer and Metastasis Reviews. 33, 2-3, p. 441-468 28 p.

Research output: Contribution to journalArticle

38 Scopus citations
2015

Antisense-mediated affinity purification of dengue virus ribonucleoprotein complexes from infected cells

Phillips, S. L., Garcia-Blanco, M. & Bradrick, S., Jul 6 2015, (Accepted/In press) In : Methods.

Research output: Contribution to journalArticle

4 Scopus citations

Carcinosarcomas: Tumors in transition?

Somarelli, J. A., Boss, M. K., Epstein, J. I., Armstrong, A. J. & Garcia-Blanco, M., 2015, In : Histology and Histopathology. 30, 6, p. 673-687 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness

Manokaran, G., Finol, E., Wang, C., Gunaratne, J., Bahl, J., Ong, E. Z., Tan, H. C., Sessions, O. M., Ward, A. M., Gubler, D. J., Harris, E., Garcia-Blanco, M. & Ooi, E. E., Oct 9 2015, In : Science. 350, 6257, p. 217-221 5 p.

Research output: Contribution to journalArticle

162 Scopus citations

Know thyself

Garcia-Blanco, M. A., Apr 1 2015, In : RNA. 21, 4, p. 525-526 2 p.

Research output: Contribution to journalShort survey

2 Scopus citations

RNA: Jack of all trades and master of all

Pompon, J. & Garcia-Blanco, M. A., Feb 12 2015, In : Cell. 160, 4, p. 579-580 2 p.

Research output: Contribution to journalShort survey

RNA-based methods in virology

Bradrick, S. & Garcia-Blanco, M., 2015, In : Methods. 91, p. 1-2 2 p.

Research output: Contribution to journalArticle

Using circulating tumor cells to inform on prostate cancer biology and clinical utility

Li, J., Gregory, S. G., Garcia-Blanco, M. & Armstrong, A. J., Jul 4 2015, In : Critical Reviews in Clinical Laboratory Sciences. 52, 4, p. 191-210 20 p.

Research output: Contribution to journalArticle

17 Scopus citations
2016

A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection

Barrows, N. J., Kroon Campos, R., Powell, S. T., Prasanth, K. R., Schott-Lerner, G., Soto-Acosta, R., Galarza-Munoz, G., McGrath, E. L., Urrabaz-Garza, R., Gao, J., Wu, P., Menon, R., Saade, G., Fernandez-Salas, I., Rossi, S., Vasilakis, N., Routh, A., Bradrick, S. & Garcia-Blanco, M., May 15 2016, (Accepted/In press) In : Cell Host and Microbe.

Research output: Contribution to journalArticle

198 Scopus citations

Development of a novel c-MET-Based CTC detection platform

Zhang, T., Boominathan, R., Foulk, B., Rao, C., Kemeny, G., Strickler, J. H., Abbruzzese, J. L., Harrison, M. R., Hsu, D. S., Healy, P., Li, J., Pi, C., Prendergast, K. M., Hobbs, C., Gemberling, S., George, D. J., Hurwitz, H. I., Connelly, M., Garcia-Blanco, M. A. & Armstrong, A. J., Jun 2016, In : Molecular Cancer Research. 14, 6, p. 539-547 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Distinct routes to metastasis: Plasticity-dependent and plasticity-independent pathways

Somarelli, J. A., Schaeffer, D., Marengo, M. S., Bepler, T., Rouse, D., Ware, K. E., Hish, A. J., Zhao, Y., Buckley, A. F., Epstein, J. I., Armstrong, A. J., Virshup, D. M. & Garcia-Blanco, M., Aug 18 2016, In : Oncogene. 35, 33, p. 4302-4311 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Flavivirus RNA transactions from viral entry to genome replication

Garcia-Blanco, M., Vasudevan, S. G., Bradrick, S. & Nicchitta, C., Oct 1 2016, In : Antiviral Research. 134, p. 244-249 6 p.

Research output: Contribution to journalReview article

26 Scopus citations

Identification of proteins bound to dengue viral RNA In Vivo reveals new host proteins important for virus replication

Phillips, S. L., Soderblom, E. J., Bradrick, S. S. & Garcia-Blanco, M. A., Jan 5 2016, In : mBio. 7, 1, e01865-15.

Research output: Contribution to journalArticle

20 Scopus citations

Mesenchymal-epithelial transition in sarcomas is controlled by the combinatorial expression of microRNA 200s and GRHL2

Somarelli, J. A., Shetler, S., Jolly, M. K., Wang, X., Bartholf Dewitt, S., Hish, A. J., Gilja, S., Eward, W. C., Ware, K. E., Levine, H., Armstrong, A. J. & Garcia-Blanco, M. A., Jan 1 2016, In : Molecular and cellular biology. 36, 19, p. 2503-2513 11 p.

Research output: Contribution to journalArticle

29 Scopus citations