Mariano Garcia-Blanco, MD, PhD

Chair

  • 10294 Citations
  • 53 h-Index
1975 …2020

Research output per year

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Research Output

Short survey

Know thyself

Garcia-Blanco, M. A., Apr 1 2015, In : RNA. 21, 4, p. 525-526 2 p.

Research output: Contribution to journalShort survey

2 Scopus citations

Mending the message

Garcia-Blanco, M. A., Dec 1 2003, In : Nature Biotechnology. 21, 12, p. 1448-1449 2 p.

Research output: Contribution to journalShort survey

7 Scopus citations

Minireview: Polypyrimidine tract binding protein antagonizes exon definition

Wagner, E. J. & Garcia-Blanco, M. A., Jan 1 2001, In : Molecular and cellular biology. 21, 10, p. 3281-3288 8 p.

Research output: Contribution to journalShort survey

291 Scopus citations

RNA: Jack of all trades and master of all

Pompon, J. & Garcia-Blanco, M. A., Feb 12 2015, In : Cell. 160, 4, p. 579-580 2 p.

Research output: Contribution to journalShort survey

Shedding UV Light on Alternative Splicing

Marengo, M. S. & Garcia-Blanco, M. A., May 15 2009, In : Cell. 137, 4, p. 600-602 3 p.

Research output: Contribution to journalShort survey

2 Scopus citations
Review article

Alternative splicing: therapeutic target and tool.

Garcia-Blanco, M. A., 2006, In : Progress in molecular and subcellular biology. 44, p. 47-64 18 p.

Research output: Contribution to journalReview article

26 Scopus citations

Alternative splicing in disease and therapy

Garcia-Blanco, M. A., Baraniak, A. P. & Lasda, E. L., May 1 2004, In : Nature Biotechnology. 22, 5, p. 535-546 12 p.

Research output: Contribution to journalReview article

401 Scopus citations

Alternative splicing in multiple sclerosis and other autoimmune diseases

Evsyukova, I., Somarelli, J. A., Gregory, S. G. & Garcia-Blanco, M. A., Jan 1 2010, In : RNA Biology. 7, 4, p. 462-473 12 p.

Research output: Contribution to journalReview article

32 Scopus citations

Biologic and clinical significance of androgen receptor variants in castration resistant prostate cancer

Ware, K. E., Garcia-Blanco, M. A., Armstrong, A. J. & Dehm, S. M., Aug 2014, In : Endocrine-Related Cancer. 21, 4, p. T87-T103

Research output: Contribution to journalReview article

87 Scopus citations

Co-transcriptional splicing of pre-messenger RNAs: Considerations for the mechanism of alternative splicing

Goldstrohm, A. C., Greenleaf, A. L. & Garcia-Blanco, M. A., Oct 17 2001, In : Gene. 277, 1-2, p. 31-47 17 p.

Research output: Contribution to journalReview article

135 Scopus citations

Early history of circular RNAs, children of splicing

Pasman, Z. & Garcia-Blanco, M., Aug 3 2017, In : RNA Biology. 14, 8, p. 975-977 3 p.

Research output: Contribution to journalReview article

2 Scopus citations

Flaviviral RNAs: Weapons and targets in the war between virus and host

Bidet, K. & Garcia-Blanco, M. A., Sep 1 2014, In : Biochemical Journal. 462, 2, p. 215-230 16 p.

Research output: Contribution to journalReview article

42 Scopus citations

Flavivirus RNA transactions from viral entry to genome replication

Garcia-Blanco, M., Vasudevan, S. G., Bradrick, S. & Nicchitta, C., Oct 1 2016, In : Antiviral Research. 134, p. 244-249 6 p.

Research output: Contribution to journalReview article

26 Scopus citations

Making antisense of splicing

Garcia-Blanco, M. A., Oct 1 2005, In : Current Opinion in Molecular Therapeutics. 7, 5, p. 476-482 7 p.

Research output: Contribution to journalReview article

19 Scopus citations

Messenger RNA reprogramming by spliceosome-mediated RNA trans-splicing

Garcia-Blanco, M. A., Aug 1 2003, In : Journal of Clinical Investigation. 112, 4, p. 474-480 7 p.

Research output: Contribution to journalReview article

59 Scopus citations

Targeting host factors to treat West Nile and dengue viral infections

Krishnan, M. N. & Garcia-Blanco, M. A., Feb 10 2014, In : Viruses. 6, 2, p. 683-708 26 p.

Research output: Contribution to journalReview article

43 Scopus citations

The 5ʹ and 3ʹ untranslated regions of the flaviviral genome

Ng, W. C., Soto-Acosta, R., Bradrick, S. S., Garcia-Blanco, M. A. & Ooi, E. E., Jun 2017, In : Viruses. 9, 6, 137.

Research output: Contribution to journalReview article

40 Scopus citations

Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network

Aliota, M. T., Bassit, L., Bradrick, S., Cox, B., Garcia-Blanco, M., Gavegnano, C., Friedrich, T. C., Golos, T. G., Griffin, D. E., Haddow, A. D., Kallas, E. G., Kitron, U., Lecuit, M., Magnani, D. M., Marrs, C., Mercer, N., McSweegan, E., Ng, L. F. P., O'Connor, D. H., Osorio, J. E. & 11 others, Ribeiro, G. S., Ricciardi, M., Rossi, S., Saade, G., Schinazi, R. F., Schott-Lerner, G. O., Shan, C., Shi, P-Y., Watkins, D. I., Vasilakis, N. & Weaver, S., Aug 1 2017, In : Antiviral Research. 144, p. 223-246 24 p.

Research output: Contribution to journalReview article

57 Scopus citations
Letter

A "microRNA-like" small RNA expressed by Dengue virus?

Skalsky, R. L., Olson, K. E., Blair, C. D., Garcia-Blanco, M. A. & Cullen, B. R., Jun 10 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 23, p. E2359

Research output: Contribution to journalLetter

17 Scopus citations
Editorial

Editorial: Biotechnology and Puerto Rico: Promises that must be kept

García-Blanco, M. A., Oct 26 2009, In : Puerto Rico health sciences journal. 28, 3, p. 217-218 2 p.

Research output: Contribution to journalEditorial

Comment/debate

Corrigendum: Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer

Wang, B. D., Ceniccola, K., Hwang, S. J., Andrawis, R., Horvath, A., Freedman, J. A., Olender, J., Knapp, S., Ching, T., Garmire, L., Patel, V., Garcia-Blanco, M. A., Patierno, S. R. & Lee, N. H., Sep 27 2017, In : Nature communications. 8, 1 p., 16161.

Research output: Contribution to journalComment/debate

Epithelial-mesenchymal transition in prostate cancer: Providing new targets for therapy

Armstrong, A. J., Freedland, S. J. & Garcia-Blanco, M., Mar 1 2011, In : Asian Journal of Andrology. 13, 2, p. 179-180 2 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Erratum: Spliceosome-mediated RNA trans-splicing as a tool for gene therapy (Nature Biotechnol. (1999) 17 (246-252))

Puttaraju, M., Jamison, S. F., Mansfield, S. G., Garcia-Blanco, M. A. & Mitchell, L. G., Jan 1 2001, In : Nature Biotechnology. 19, 3, 1 p.

Research output: Contribution to journalComment/debate

Erratum: Spliceosome-mediated RNA trans-splicing as a tool for gene therapy (Nature Biotechnology)

Puttaruju, M., Jamison, S. F., Mansfield, G., Garcia-Blanco, M. A. & Mitchell, L. G., Jan 1 1999, In : Nature Biotechnology. 17, 6, 1 p.

Research output: Contribution to journalComment/debate

Chapter

A novel isoform ratio switch of the polypyrimidine tract binding protein

Wagner, E., Carstens, R. P. & Garcia-Blanco, M., Dec 26 2007, From Genome to Proteome: Advances in the Practice & Application of Proteomics. Wiley Blackwell, p. 502-506 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Flaviviral RNA structures and their role in replication and immunity

Bidet, K. & Garcia-Blanco, M., Jan 1 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 45-62 18 p. (Advances in Experimental Medicine and Biology; vol. 1062).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Quantification of microRNAs, splicing isoforms, and homologous mRNAs with the invader assay

Eis, P. S. & Garcia-Blanco, M., 2008, Methods in Molecular Biology. Humana Press, Vol. 488. p. 279-318 40 p. (Methods in Molecular Biology; vol. 488).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Roles of pro-viral host factors in mosquito-borne flavivirus infections

Kroon Campos, R., Garcia-Blanco, M. & Bradrick, S., Jan 1 2018, Current Topics in Microbiology and Immunology. Springer Verlag, p. 43-67 25 p. (Current Topics in Microbiology and Immunology; vol. 419).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

The interface between dengue virus and the human host

Barrows, N. J., Bradrick, S. S., Bidet, K., Anwar, A., Ward, A. M., Jamison, S. F., Levitt, B., Le Sommer, C. & Garcia-Blanco, M. A., Aug 29 2014, Dengue and Dengue Hemorrhagic Fever: Second Edition. CABI International, p. 406-424 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Article

5′ Exon replacement and repair by spliceosome-mediated RNA trans-splicing

Mansfield, S. G., Clark, R. H., Puttaraju, M., Kole, J., Cohn, J. A., Mitchell, L. G. & Garcia-Blanco, M. A., Oct 1 2003, In : RNA. 9, 10, p. 1290-1297 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

A functional alternative splicing mutation in human tryptophan hydroxylase-2

Zhang, X., Nicholls, P. J., Laje, G., Sotnikova, T. D., Gainetdinov, R. R., Albert, P. R., Rajkowska, G., Stockmeier, C. A., Speer, M. C., Steffens, D. C., Austin, M. C., McMahon, F. J., Krishnan, K. R. R., Garcia-Blanco, M. A. & Caron, M. G., Dec 1 2011, In : Molecular Psychiatry. 16, 12, p. 1169-1176 8 p.

Research output: Contribution to journalArticle

20 Scopus citations
8 Scopus citations

Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostrate tumors reveals unexpected epithelial mesenchymal plasticity

Oltean, S., Sorg, B. S., Albrecht, T., Bonano, V. I., Brazas, R. M., Dewhirst, M. W. & Garcia-Blanco, M. A., Sep 19 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 38, p. 14116-14121 6 p.

Research output: Contribution to journalArticle

81 Scopus citations

Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) in human prostate cancer

Carstens, R. P., Eaton, J. V., Krigman, H. R., Walther, P. J. & Garcia-Blanco, M. A., Dec 18 1997, In : Oncogene. 15, 25, p. 3059-3065 7 p.

Research output: Contribution to journalArticle

Open Access
128 Scopus citations

Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer

Wang, B. D., Ceniccola, K., Hwang, S., Andrawis, R., Horvath, A., Freedman, J. A., Olender, J., Knapp, S., Ching, T., Garmire, L., Patel, V., Garcia-Blanco, M. A., Patierno, S. R. & Lee, N. H., Jun 30 2017, In : Nature communications. 8, 15921.

Research output: Contribution to journalArticle

33 Scopus citations

A mammalian activity required for the second step of pre-messenger RNA splicing

Lindsey, L. A., Crow, A. J. & Garcia-Blanco, M. A., Jan 1 1995, In : Journal of Biological Chemistry. 270, 22, p. 13415-13421 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
Open Access
38 Scopus citations

A mutational analysis of the polypyrimidine tract of introns. Effects of sequence differences in pyrimidine tracts on splicing

Roscigno, R. F., Weiner, M. & Garcia-Blanco, M. A., Jan 1 1993, In : Journal of Biological Chemistry. 268, 15, p. 11222-11229 8 p.

Research output: Contribution to journalArticle

127 Scopus citations
Open Access
26 Scopus citations

A new approach to the study of immunity to schistosomes.

Hillyer, G. V., del Llano de Díaz, A. & García-Blanco, M., Dec 1 1975, In : Boletin de la Asociacion Medica de Puerto Rico. 67, 12, p. 381-385 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

An intronic sequence element mediates both activation and repression of rat fibroblast growth factor receptor 2 pre-mRNA splicing

Carstens, R. P., Mckeehan, W. L. & Garcia-Blanco, M. A., Apr 1998, In : Molecular and cellular biology. 18, 4, p. 2205-2217 13 p.

Research output: Contribution to journalArticle

Open Access
82 Scopus citations
119 Scopus citations
13 Scopus citations

A novel isoform ratio switch of the polypyrimidine tract binding protein

Wagner, E. J., Carstens, R. P. & Garcia-Blanco, M. A., Jan 1 1999, In : ELECTROPHORESIS. 20, 4-5, p. 1082-1086 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Antisense-mediated affinity purification of dengue virus ribonucleoprotein complexes from infected cells

Phillips, S. L., Garcia-Blanco, M. & Bradrick, S., Jul 6 2015, (Accepted/In press) In : Methods.

Research output: Contribution to journalArticle

4 Scopus citations

A protocol for imaging alternative splicing regulation in vivo using fluorescence reporters in transgenic mice

Bonano, V. I., Oltean, S. & Garcia-Blanco, M. A., Sep 1 2007, In : Nature Protocols. 2, 9, p. 2166-2181 16 p.

Research output: Contribution to journalArticle

23 Scopus citations

A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection

Barrows, N. J., Kroon Campos, R., Powell, S. T., Prasanth, K. R., Schott-Lerner, G., Soto-Acosta, R., Galarza-Munoz, G., McGrath, E. L., Urrabaz-Garza, R., Gao, J., Wu, P., Menon, R., Saade, G., Fernandez-Salas, I., Rossi, S., Vasilakis, N., Routh, A., Bradrick, S. & Garcia-Blanco, M., May 15 2016, (Accepted/In press) In : Cell Host and Microbe.

Research output: Contribution to journalArticle

198 Scopus citations

A serine/arginine-rich domain in the human U1 70k protein is necessary and sufficient for ASF/SF2 binding

Cao, W. & Garcia-Blanco, M. A., Aug 7 1998, In : Journal of Biological Chemistry. 273, 32, p. 20629-20635 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

A small circular TAR RNA decoy specifically inhibits Tat-activated HIV-1 transcription

Bohjanen, P. R., Colvin, R. A., Puttaraju, M., Been, M. D. & Garcia-Blanco, M. A., 1996, In : Nucleic acids research. 24, 19, p. 3733-3738 6 p.

Research output: Contribution to journalArticle

53 Scopus citations