Mariano Garcia-Blanco, MD, PhD

Chair

  • 10294 Citations
  • 53 h-Index
1975 …2020

Research output per year

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Research Output

Development of a novel c-MET-Based CTC detection platform

Zhang, T., Boominathan, R., Foulk, B., Rao, C., Kemeny, G., Strickler, J. H., Abbruzzese, J. L., Harrison, M. R., Hsu, D. S., Healy, P., Li, J., Pi, C., Prendergast, K. M., Hobbs, C., Gemberling, S., George, D. J., Hurwitz, H. I., Connelly, M., Garcia-Blanco, M. A. & Armstrong, A. J., Jun 2016, In : Molecular Cancer Research. 14, 6, p. 539-547 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Discovery of insect and human dengue virus host factors

Sessions, O. M., Barrows, N. J., Souza-Neto, J. A., Robinson, T. J., Hershey, C. L., Rodgers, M. A., Ramirez, J. L., Dimopoulos, G., Yang, P. L., Pearson, J. L. & Garcia-Blanco, M. A., Apr 23 2009, In : Nature. 458, 7241, p. 1047-1050 4 p.

Research output: Contribution to journalArticle

278 Scopus citations

Distinct routes to metastasis: Plasticity-dependent and plasticity-independent pathways

Somarelli, J. A., Schaeffer, D., Marengo, M. S., Bepler, T., Rouse, D., Ware, K. E., Hish, A. J., Zhao, Y., Buckley, A. F., Epstein, J. I., Armstrong, A. J., Virshup, D. M. & Garcia-Blanco, M., Aug 18 2016, In : Oncogene. 35, 33, p. 4302-4311 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis

Barrows, N. J., Anglero-Rodriguez, Y., Kim, B., Jamison, S. F., Le Sommer, C., McGee, C. E., Pearson, J. L., Dimopoulos, G., Ascano, M., Bradrick, S. S. & Garcia-Blanco, M. A., Dec 1 2019, In : Scientific reports. 9, 1, 9711.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
19 Scopus citations

Early history of circular RNAs, children of splicing

Pasman, Z. & Garcia-Blanco, M., Aug 3 2017, In : RNA Biology. 14, 8, p. 975-977 3 p.

Research output: Contribution to journalReview article

2 Scopus citations

Editorial: Biotechnology and Puerto Rico: Promises that must be kept

García-Blanco, M. A., Oct 26 2009, In : Puerto Rico health sciences journal. 28, 3, p. 217-218 2 p.

Research output: Contribution to journalEditorial

Effect of human gamma interferon on yellow fever virus infection

Arroyo, J. I., Apperson, S. A., Cropp, C. B., Marafino, B. J., Monath, T. P., Tesh, R. B., Shope, R. E. & Garcia-Blanco, M. A., Jan 1 1988, In : American Journal of Tropical Medicine and Hygiene. 38, 3, p. 647-650 4 p.

Research output: Contribution to journalArticle

25 Scopus citations

Epithelial-mesenchymal transition in prostate cancer: Providing new targets for therapy

Armstrong, A. J., Freedland, S. J. & Garcia-Blanco, M., Mar 1 2011, In : Asian Journal of Andrology. 13, 2, p. 179-180 2 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Epstein-barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency

Homa, N. J., Salinas, R., Forte, E., Robinson, T. J., Garcia-Blanco, M. A. & Luftig, M. A., 2013, In : Journal of virology. 87, 22, p. 12291-12301 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Erratum: Spliceosome-mediated RNA trans-splicing as a tool for gene therapy (Nature Biotechnol. (1999) 17 (246-252))

Puttaraju, M., Jamison, S. F., Mansfield, S. G., Garcia-Blanco, M. A. & Mitchell, L. G., Jan 1 2001, In : Nature Biotechnology. 19, 3, 1 p.

Research output: Contribution to journalComment/debate

Erratum: Spliceosome-mediated RNA trans-splicing as a tool for gene therapy (Nature Biotechnology)

Puttaruju, M., Jamison, S. F., Mansfield, G., Garcia-Blanco, M. A. & Mitchell, L. G., Jan 1 1999, In : Nature Biotechnology. 17, 6, 1 p.

Research output: Contribution to journalComment/debate

Exon circularization in mammalian nuclear extracts

Pasman, Z., Been, M. D. & Garcia-Blanco, M. A., Nov 19 1996, In : RNA. 2, 6, p. 603-610 8 p.

Research output: Contribution to journalArticle

103 Scopus citations

Expression analysis and mapping of the mouse and human transcriptional regulator CA150

Bohne, J., Cole, S. E., Suñe, C., Lindman, B. R., Ko, V. D., Vogt, T. F. & Garcia-Blanco, M. A., Jan 1 2000, In : Mammalian Genome. 11, 10, p. 930-933 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Factors affecting reproducibility between genome-scale siRNA-based screens

Barrows, N. J., Le Sommer, C., Garcia-Blanco, M. A. & Pearson, J. L., Aug 2010, In : Journal of Biomolecular Screening. 15, 7, p. 735-747 13 p.

Research output: Contribution to journalArticle

35 Scopus citations

Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing

Simarro, M., Mauger, D., Rhee, K., Pujana, M. A., Kedersha, N. L., Yamasaki, S., Cusick, M. E., Vidal, M., Garcia-Blanco, M. A. & Anderson, P., Jul 3 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 27, p. 11370-11375 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Fasciola hepatica: Molecular cloning, nucleotide sequence, and expression of a gene encoding a polypeptide homologous to a Schistosoma mansoni fatty acid-binding protein

Rodríguez-Pérez, J., Rodrǵuez-Medina, J. R., García-Blanco, M. A. & Hillyer, G. V., Jun 1992, In : Experimental Parasitology. 74, 4, p. 400-407 8 p.

Research output: Contribution to journalArticle

93 Scopus citations

Flaviviral RNAs: Weapons and targets in the war between virus and host

Bidet, K. & Garcia-Blanco, M. A., Sep 1 2014, In : Biochemical Journal. 462, 2, p. 215-230 16 p.

Research output: Contribution to journalReview article

42 Scopus citations

Flaviviral RNA structures and their role in replication and immunity

Bidet, K. & Garcia-Blanco, M., Jan 1 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 45-62 18 p. (Advances in Experimental Medicine and Biology; vol. 1062).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Flavivirus RNA transactions from viral entry to genome replication

Garcia-Blanco, M., Vasudevan, S. G., Bradrick, S. & Nicchitta, C., Oct 1 2016, In : Antiviral Research. 134, p. 244-249 6 p.

Research output: Contribution to journalReview article

26 Scopus citations

Fluorescence-based alternative splicing reporters for the study of epithelial plasticity in vivo

Somarelli, J. A., Schaeffer, D., Bosma, R., Bonano, V. I., Sohn, J. W., Kemeny, G., Ettyreddy, A. & Garcia-Blanco, M. A., Jan 2013, In : RNA. 19, 1, p. 116-127 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Fox-2 mediates epithelial cell-specific fibroblast growth factor receptor 2 exon choice

Baraniak, A. P., Chen, J. R. & Garcia-Blanco, M. A., Feb 1 2006, In : Molecular and cellular biology. 26, 4, p. 1209-1222 14 p.

Research output: Contribution to journalArticle

87 Scopus citations

Fragile X mental retardation protein is a zika virus restriction factor that is antagonized by subgenomic flaviviral RNA

Soto-Acosta, R., Xie, X., Shan, C., Baker, C. K., Shi, P. Y., Rossi, S. L., Garcia-Blanco, M. A. & Bradrick, S., Dec 1 2018, In : eLife. 7, e39023.

Research output: Contribution to journalArticle

10 Scopus citations

Functional conservation of the human homolog of the yeast pre-mRNA splicing factor Prp17p

Lindsey, L. A. & Garcia-Blanco, M. A., Dec 4 1998, In : Journal of Biological Chemistry. 273, 49, p. 32771-32775 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Functional Genomics Approach for the Identification of Human Host Factors Supporting Dengue Viral Propagation

Barrows, N. J., Jamison, S. F., Bradrick, S. S., Le Sommer, C., Kim, S. Y., Pearson, J. & Garcia-Blanco, M. A., Jan 1 2014, In : Methods in Molecular Biology. 1138, p. 285-299 15 p.

Research output: Contribution to journalArticle

6 Scopus citations
125 Scopus citations

G Protein-Coupled Receptor Kinase 2 Promotes Flaviviridae Entry and Replication

Le Sommer, C., Barrows, N. J., Bradrick, S. S., Pearson, J. L. & Garcia-Blanco, M. A., Sep 2012, In : PLoS neglected tropical diseases. 6, 9, e1820.

Research output: Contribution to journalArticle

48 Scopus citations

hnRNP H and hnRNP F complex with Fox2 to silence fibroblast growth factor receptor 2 exon IIIc

Mauger, D. M., Lin, C. & Garcia-Blanco, M. A., Sep 2008, In : Molecular and cellular biology. 28, 17, p. 5403-5419 17 p.

Research output: Contribution to journalArticle

82 Scopus citations

Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk

Galarza-Munoz, G., Briggs, F. B. S., Evsyukova, I., Schott-Lerner, G., Kennedy, E. M., Nyanhete, T., Wang, L., Bergamaschi, L., Widen, S., Tomaras, G. D., Ko, D. C., Bradrick, S., Barcellos, L. F., Gregory, S. G. & Garcia-Blanco, M., Mar 23 2017, In : Cell. 169, 1, p. 72-84.e13

Research output: Contribution to journalArticle

28 Scopus citations

Human immunodeficiency virus type 1 Tat-dependent activation of an arrested RNA polymerase II elongation complex

Liu, Y., Suñé, C. & Garcia-Blanco, M. A., Mar 15 1999, In : Virology. 255, 2, p. 337-346 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
46 Scopus citations
152 Scopus citations

Identification and characterization of host proteins bound to dengue virus 3' UTR reveal an antiviral role for quaking proteins

Liao, K. C., Chuo, V., Ng, W. C., Neo, S. P., Pompon, J., Gunaratne, J., Ooi, E. E. & Garcia-Blanco, M. A., Jun 2018, In : RNA. 24, 6, p. 803-814 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns

Garcia-Blanco, M. A., Jamison, S. F. & Sharp, P. A., 1989, In : Genes and Development. 3, 12 A, p. 1874-1886 13 p.

Research output: Contribution to journalArticle

Open Access
230 Scopus citations

Identification of an intronic splicing enhancer essential for the inclusion of FGFR2 exon IIIc

Seth, P., Miller, H. B., Lasda, E. L., Pearson, J. L. & Garcia-Blanco, M. A., Apr 11 2008, In : Journal of Biological Chemistry. 283, 15, p. 10058-10067 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Identification of dengue RNA binding proteins using RNA chromatography and quantitative mass spectrometry

Ward, A. M., Gunaratne, J. & Garcia-Blanco, M. A., Jan 1 2014, In : Methods in Molecular Biology. 1138, p. 253-270 18 p.

Research output: Contribution to journalArticle

10 Scopus citations

Identification of proteins bound to dengue viral RNA In Vivo reveals new host proteins important for virus replication

Phillips, S. L., Soderblom, E. J., Bradrick, S. S. & Garcia-Blanco, M. A., Jan 5 2016, In : mBio. 7, 1, e01865-15.

Research output: Contribution to journalArticle

20 Scopus citations

Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing

Miller, H. B., Robinson, T. J., Gordân, R., Hartemink, A. J. & Garcia-Blanco, M. A., Apr 1 2011, In : RNA. 17, 4, p. 665-674 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Identification of the cellular targets of the transcription factor TCERG1 reveals a prevalent role in mrna processing

Pearson, J. L., Robinson, T. J., Muñoz, M. J., Kornblihtt, A. R. & Garcia-Blanco, M. A., Mar 21 2008, In : Journal of Biological Chemistry. 283, 12, p. 7949-7961 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Imaging alternative splicing in living cells.

Wagner, E. J., Baines, A., Albrecht, T., Brazas, R. M. & Garcia-Blanco, M. A., 2004, In : Methods in molecular biology (Clifton, N.J.). 257, p. 29-46 18 p.

Research output: Contribution to journalArticle

12 Scopus citations

Imaging the alternative silencing of FGFR2 exon IIIb in vivo

Bonano, V. I., Oltean, S., Brazas, R. M. & Garcia-Blanco, M. A., Dec 2006, In : RNA. 12, 12, p. 2073-2079 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Interferon action: Effects of mouse α and β interferons on rosette formation, phagocytosis, and surface-antigen expression of cells of the macrophage-type line RAW 309Cr.1

Yoshie, O., Mellman, I. S., Broeze, R. J., Garcia-Blanco, M. & Lengyel, P., Oct 1982, In : Cellular Immunology. 73, 1, p. 128-140 13 p.

Research output: Contribution to journalArticle

19 Scopus citations

Interferons as gene activators. Cloning of the 5' terminus and the control segment of an interferon activated gene

Samanta, H., Engel, D. A., Chao, H. M., Thakur, A., García-Blanco, M. A. & Lengyel, P., 1986, In : Journal of Biological Chemistry. 261, 25, p. 11849-11858 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

Interleukin 7 receptor α chain (IL7R) shows allelic and functional association with multiple sclerosis

Gregory, S. G., Schmidt, S., Seth, P., Oksenberg, J. R., Hart, J., Prokop, A., Caillier, S. J., Ban, M., Goris, A., Barcellos, L. F., Lincoln, R., McCauley, J. L., Sawcer, S. J., Compston, D. A. S., Dubois, B., Hauser, S. L., Garcia-Blanco, M. A., Pericak-Vance, M. A. & Haines, J. L., Sep 1 2007, In : Nature Genetics. 39, 9, p. 1083-1091 9 p.

Research output: Contribution to journalArticle

479 Scopus citations

In vitro coupled transcription splicing

Natalizio, B. J. & Garcia-Blanco, M. A., Dec 1 2005, In : Methods. 37, 4, p. 314-322 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Know thyself

Garcia-Blanco, M. A., Apr 1 2015, In : RNA. 21, 4, p. 525-526 2 p.

Research output: Contribution to journalShort survey

2 Scopus citations

Making antisense of splicing

Garcia-Blanco, M. A., Oct 1 2005, In : Current Opinion in Molecular Therapeutics. 7, 5, p. 476-482 7 p.

Research output: Contribution to journalReview article

19 Scopus citations

MAZ elements alter transcription elongation and silencing of the fibroblast growth factor receptor 2 exon IIIb

Robson-Dixon, N. D. & Garcia-Blanco, M. A., Jul 9 2004, In : Journal of Biological Chemistry. 279, 28, p. 29075-29084 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Mending the message

Garcia-Blanco, M. A., Dec 1 2003, In : Nature Biotechnology. 21, 12, p. 1448-1449 2 p.

Research output: Contribution to journalShort survey

7 Scopus citations