Mariano Garcia-Blanco, MD, PhD

Chair

  • 9894 Citations
  • 52 h-Index
1975 …2020
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Research Output 1975 2019

  • 9894 Citations
  • 52 h-Index
  • 163 Article
  • 5 Chapter
  • 4 Review article
  • 1 Comment/debate
1993
126 Citations (Scopus)

A mutational analysis of the polypyrimidine tract of introns: Effects of sequence differences in pyrimidine tracts on splicing

Roecigno, R. F., Weiner, M. & Garcia-Blanco, M., May 25 1993, In : Journal of Biological Chemistry. 268, 15, p. 11222-11229 8 p.

Research output: Contribution to journalArticle

RNA Precursors
Introns
Spliceosomes
Uracil
Heterogeneous-Nuclear Ribonucleoprotein Group C
24 Citations (Scopus)

Structural features of an RNA containing the CUGGGA loop of the human immunodeficiency virus type 1 trans-activation response element

Colvin, R. A., White, S. W., Garcia-Blanco, M. & Hoffman, D. W., 1993, In : Biochemistry. 32, 4, p. 1105-1112 8 p.

Research output: Contribution to journalArticle

Response Elements
Viruses
HIV-1
Nucleotides
Chemical activation
19 Citations (Scopus)

Structural features of the trans-activation response RNA element of equine infectious anemia virus

Huffman, D. W., Colvin, R. A., Garcia-Blanco, M. & White, S. W., 1993, In : Biochemistry. 32, 4, p. 1096-1104 9 p.

Research output: Contribution to journalArticle

Equine infectious anemia virus
Response Elements
Viruses
Nucleotides
Chemical activation
1992
25 Citations (Scopus)
U2 Small Nuclear Ribonucleoproteins
Small Nuclear Ribonucleoproteins
RNA Precursors
Adenosine Triphosphate
RNA Splice Sites
93 Citations (Scopus)

Fasciola hepatica: Molecular cloning, nucleotide sequence, and expression of a gene encoding a polypeptide homologous to a Schistosoma mansoni fatty acid-binding protein

Rodríguez-Pérez, J., Rodrǵuez-Medina, J., Garcia-Blanco, M. & Hillyer, G. V., 1992, In : Experimental Parasitology. 74, 4, p. 400-407 8 p.

Research output: Contribution to journalArticle

Fasciola hepatica
Fatty Acid-Binding Proteins
Schistosoma mansoni
Molecular Cloning
Fasciola
73 Citations (Scopus)

The Spliceosome Assembly Pathway in Mammalian Extracts

Jamison, S. F., Crow, A. & Garcia-Blanco, M., Oct 1992, In : Molecular and Cellular Biology. 12, 10, p. 4279-4287 9 p.

Research output: Contribution to journalArticle

U1 Small Nuclear Ribonucleoproteins
Spliceosomes
U2 Small Nuclear Ribonucleoproteins
Small Nuclear Ribonucleoproteins
RNA
40 Citations (Scopus)

Unusual structure of the human immunodeficiency virus type 1 trans-activation response element

Colvin, R. A. & Garcia-Blanco, M., Feb 1992, In : Journal of Virology. 66, 2, p. 930-935 6 p.

Research output: Contribution to journalArticle

response elements
Response Elements
transcriptional activation
Human immunodeficiency virus 1
HIV-1
1991
210 Citations (Scopus)

Characterization of cDNAs encoding the polypyrimidine tract-binding protein

Gil, A., Sharp, P. A., Jamison, S. F. & Garcia-Blanco, M., Jul 1991, In : Genes and Development. 5, 7, p. 1224-1236 13 p.

Research output: Contribution to journalArticle

Polypyrimidine Tract-Binding Protein
Complementary DNA
Heterogeneous-Nuclear Ribonucleoprotein L
U2 Small Nuclear Ribonucleoproteins
Heterogeneous-Nuclear Ribonucleoproteins
108 Citations (Scopus)

Molecular basis of latency in pathogenic human viruses

Garcia-Blanco, M. & Cullen, B. R., Nov 8 1991, In : Science. 254, 5033, p. 815-820 6 p.

Research output: Contribution to journalArticle

Viral Regulatory and Accessory Proteins
Viruses
Health Services Needs and Demand
Viral Proteins
Simplexvirus
38 Citations (Scopus)

Murine polypyrimidine tract binding protein: Purification, cloning, and mapping of the RNA binding domain

Bothwell, A. L. M., Ballard, D. W., Philbrick, W. M., Lindwall, G., Maher, S. E., Bridgett, M. M., Jamison, S. F. & Garcia-Blanco, M., Dec 25 1991, In : Journal of Biological Chemistry. 266, 36, p. 24657-24663 7 p.

Research output: Contribution to journalArticle

Polypyrimidine Tract-Binding Protein
Cloning
Purification
Organism Cloning
RNA
1990
37 Citations (Scopus)
Spliceosomes
Fungal Proteins
RNA Precursors
Yeasts
Proteins
146 Citations (Scopus)
Response Elements
Nuclear Proteins
HIV
RNA
tat Gene Products

The beta-interferon-mediated antimitogenic state resembles the anti-viral state

Garcia-Blanco, M., Porter, J. A., Morrison, E. D. & Stiles, C. D., 1990, In : Oncogene Research. 5, 4, p. 323-328 6 p.

Research output: Contribution to journalArticle

Interferon-beta
Interferons
Proto-Oncogene Proteins c-sis
3T3 Cells
myc Genes
1989
227 Citations (Scopus)

Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns

Garcia-Blanco, M., Jamison, S. F. & Sharp, P. A., 1989, In : Genes and Development. 3, 12 A, p. 1874-1886 13 p.

Research output: Contribution to journalArticle

RNA Precursors
Introns
RNA Splice Sites
Proteins
U2 Small Nuclear Ribonucleoproteins
26 Citations (Scopus)

Regulation of 2',5'-oligoadenylate synthetase gene expression by interferons and platelet-derived growth factor

Garcia-Blanco, M., Lengyel, P., Morrison, E., Brownlee, C., Stiles, C. D., Rutherford, M., Hannigan, G. & Williams, B. R. G., 1989, In : Molecular and Cellular Biology. 9, 3, p. 1060-1068 9 p.

Research output: Contribution to journalArticle

2',5'-Oligoadenylate Synthetase
tat Gene Products
Interferon Type I
Platelet-Derived Growth Factor
Gene Expression Regulation
37 Citations (Scopus)

The DNA-binding homeo domain of the Oct-2 protein.

Garcia-Blanco, M., Clerc, R. G. & Sharp, P. A., Jun 1989, In : Genes & development. 3, 6, p. 739-745 7 p.

Research output: Contribution to journalArticle

Nucleic Acid Sequence Homology
Molecular Sequence Data
Octamer Transcription Factors
Repressor Proteins
Protein Conformation
1988
25 Citations (Scopus)

Effect of human gamma interferon on yellow fever virus infection

Arroyo, J. I., Apperson, S. A., Cropp, C. B., Marafino, B. J., Monath, T. P., Tesh, R. B., Shope, R. E. & Garcia-Blanco, M., 1988, In : American Journal of Tropical Medicine and Hygiene. 38, 3, p. 647-650 4 p.

Research output: Contribution to journalArticle

Yellow fever virus
Saimiri
Virus Diseases
Macaca mulatta
Viremia
1986
54 Citations (Scopus)

Interferons as gene activators. Cloning of the 5' terminus and the control segment of an interferon activated gene

Samanta, H., Engel, D. A., Chao, H. M., Thakur, A., Garcia-Blanco, M. & Lengyel, P., 1986, In : Journal of Biological Chemistry. 261, 25, p. 11849-11858 10 p.

Research output: Contribution to journalArticle

Cloning
Interferons
Organism Cloning
Genes
Interferon-beta
1985
4 Citations (Scopus)

Selectivity of interferon action in simian virus 40-transformed cells superinfected with simian virus 40

Garcia-Blanco, M., Ghosh, P. K., Jayaram, B. M., Ivory, S., Lebowitz, P. & Lengyel, P., 1985, In : Journal of Virology. 53, 3, p. 893-898 6 p.

Research output: Contribution to journalArticle

Simian virus 40
interferons
Interferons
Viral Tumor Antigens
antigens
1984
36 Citations (Scopus)

The antibody response in Lyme disease

Craft, J. E., Grodzicki, R. L., Shrestha, M., Fischer, D. K., Garcia-Blanco, M. & Steere, A. C., 1984, In : Yale Journal of Biology and Medicine. 57, 4, p. 561-565 5 p.

Research output: Contribution to journalArticle

Lyme Disease
Immunosorbents
Antibody Formation
Assays
Enzyme-Linked Immunosorbent Assay
1982
19 Citations (Scopus)

Interferon action: Effects of mouse α and β interferons on rosette formation, phagocytosis, and surface-antigen expression of cells of the macrophage-type line RAW 309Cr.1

Yoshie, O., Mellman, I. S., Broeze, R. J., Garcia-Blanco, M. & Lengyel, P., 1982, In : Cellular Immunology. 73, 1, p. 128-140 13 p.

Research output: Contribution to journalArticle

Rosette Formation
Surface Antigens
Phagocytosis
Interferons
Macrophages
1979
38 Citations (Scopus)

Regulation of DNA replication in S phase nuclei by ATP and ADP pools.

Rapaport, E., Garcia-Blanco, M. & Zamecnik, P. C., Apr 1979, In : Proceedings of the National Academy of Sciences of the United States of America. 76, 4, p. 1643-1647 5 p.

Research output: Contribution to journalArticle

Interphase
Cell Nucleus
DNA Replication
S Phase
Adenosine Diphosphate
1975
17 Citations (Scopus)

A new approach to the study of immunity to schistosomes.

Hillyer, G. V., del Llano de Díaz, A. & Garcia-Blanco, M., Dec 1975, In : Boletin de la Asociacion Medica de Puerto Rico. 67, 12, p. 381-385 5 p.

Research output: Contribution to journalArticle

Rodent Diseases
Bacterial Antigens
Puerto Rico
Schistosomiasis
Cricetinae