Mariano Garcia-Blanco, MD, PhD

Chair

  • 10294 Citations
  • 53 h-Index
1975 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
Article

5′ Exon replacement and repair by spliceosome-mediated RNA trans-splicing

Mansfield, S. G., Clark, R. H., Puttaraju, M., Kole, J., Cohn, J. A., Mitchell, L. G. & Garcia-Blanco, M. A., Oct 1 2003, In : RNA. 9, 10, p. 1290-1297 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

A functional alternative splicing mutation in human tryptophan hydroxylase-2

Zhang, X., Nicholls, P. J., Laje, G., Sotnikova, T. D., Gainetdinov, R. R., Albert, P. R., Rajkowska, G., Stockmeier, C. A., Speer, M. C., Steffens, D. C., Austin, M. C., McMahon, F. J., Krishnan, K. R. R., Garcia-Blanco, M. A. & Caron, M. G., Dec 1 2011, In : Molecular Psychiatry. 16, 12, p. 1169-1176 8 p.

Research output: Contribution to journalArticle

20 Scopus citations
8 Scopus citations

Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostrate tumors reveals unexpected epithelial mesenchymal plasticity

Oltean, S., Sorg, B. S., Albrecht, T., Bonano, V. I., Brazas, R. M., Dewhirst, M. W. & Garcia-Blanco, M. A., Sep 19 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 38, p. 14116-14121 6 p.

Research output: Contribution to journalArticle

81 Scopus citations

Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) in human prostate cancer

Carstens, R. P., Eaton, J. V., Krigman, H. R., Walther, P. J. & Garcia-Blanco, M. A., Dec 18 1997, In : Oncogene. 15, 25, p. 3059-3065 7 p.

Research output: Contribution to journalArticle

Open Access
128 Scopus citations

Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer

Wang, B. D., Ceniccola, K., Hwang, S., Andrawis, R., Horvath, A., Freedman, J. A., Olender, J., Knapp, S., Ching, T., Garmire, L., Patel, V., Garcia-Blanco, M. A., Patierno, S. R. & Lee, N. H., Jun 30 2017, In : Nature communications. 8, 15921.

Research output: Contribution to journalArticle

33 Scopus citations

A mammalian activity required for the second step of pre-messenger RNA splicing

Lindsey, L. A., Crow, A. J. & Garcia-Blanco, M. A., Jan 1 1995, In : Journal of Biological Chemistry. 270, 22, p. 13415-13421 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
Open Access
38 Scopus citations

A mutational analysis of the polypyrimidine tract of introns. Effects of sequence differences in pyrimidine tracts on splicing

Roscigno, R. F., Weiner, M. & Garcia-Blanco, M. A., Jan 1 1993, In : Journal of Biological Chemistry. 268, 15, p. 11222-11229 8 p.

Research output: Contribution to journalArticle

127 Scopus citations
Open Access
26 Scopus citations

A new approach to the study of immunity to schistosomes.

Hillyer, G. V., del Llano de Díaz, A. & García-Blanco, M., Dec 1 1975, In : Boletin de la Asociacion Medica de Puerto Rico. 67, 12, p. 381-385 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

An intronic sequence element mediates both activation and repression of rat fibroblast growth factor receptor 2 pre-mRNA splicing

Carstens, R. P., Mckeehan, W. L. & Garcia-Blanco, M. A., Apr 1998, In : Molecular and cellular biology. 18, 4, p. 2205-2217 13 p.

Research output: Contribution to journalArticle

Open Access
82 Scopus citations
119 Scopus citations
13 Scopus citations

A novel isoform ratio switch of the polypyrimidine tract binding protein

Wagner, E. J., Carstens, R. P. & Garcia-Blanco, M. A., Jan 1 1999, In : ELECTROPHORESIS. 20, 4-5, p. 1082-1086 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Antisense-mediated affinity purification of dengue virus ribonucleoprotein complexes from infected cells

Phillips, S. L., Garcia-Blanco, M. & Bradrick, S., Jul 6 2015, (Accepted/In press) In : Methods.

Research output: Contribution to journalArticle

4 Scopus citations

A protocol for imaging alternative splicing regulation in vivo using fluorescence reporters in transgenic mice

Bonano, V. I., Oltean, S. & Garcia-Blanco, M. A., Sep 1 2007, In : Nature Protocols. 2, 9, p. 2166-2181 16 p.

Research output: Contribution to journalArticle

23 Scopus citations

A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection

Barrows, N. J., Kroon Campos, R., Powell, S. T., Prasanth, K. R., Schott-Lerner, G., Soto-Acosta, R., Galarza-Munoz, G., McGrath, E. L., Urrabaz-Garza, R., Gao, J., Wu, P., Menon, R., Saade, G., Fernandez-Salas, I., Rossi, S., Vasilakis, N., Routh, A., Bradrick, S. & Garcia-Blanco, M., May 15 2016, (Accepted/In press) In : Cell Host and Microbe.

Research output: Contribution to journalArticle

198 Scopus citations

A serine/arginine-rich domain in the human U1 70k protein is necessary and sufficient for ASF/SF2 binding

Cao, W. & Garcia-Blanco, M. A., Aug 7 1998, In : Journal of Biological Chemistry. 273, 32, p. 20629-20635 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

A small circular TAR RNA decoy specifically inhibits Tat-activated HIV-1 transcription

Bohjanen, P. R., Colvin, R. A., Puttaraju, M., Been, M. D. & Garcia-Blanco, M. A., 1996, In : Nucleic acids research. 24, 19, p. 3733-3738 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

Assessing incomplete deprotection of microarray oligonucleotides in situ

Dressman, H. K., Barley-Maloney, L., Rowlette, L. L., Agris, P. F. & Garcia-Blanco, M. A., Nov 1 2006, In : Nucleic acids research. 34, 19, e131.

Research output: Contribution to journalArticle

1 Scopus citations

Association of chromosome 11 locus D11S12 with histology, stage, and metastases in lung cancer

Bepler, G., Fong, K. M., Johnson, B. E., O'Briant, K. C., Daly, L. A., Zimmerman, P. V., Garcia-Blanco, M. A. & Peterson, B., Feb 25 1998, In : Cancer Detection and Prevention. 22, 1, p. 14-19 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
69 Scopus citations

Asymmetric distribution of nuclear pore complexes and the cytoplasmic localization of β2-tubulin mRNA in Chlamydomonas reinhardtii

Colón-Ramos, D. A., Salisbury, J. L., Sanders, M. A., Shenoy, S. M., Singer, R. H. & García-Blanco, M. A., Jun 1 2003, In : Developmental cell. 4, 6, p. 941-952 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Autoregulation of Polypyrimidine Tract Binding Protein by Alternative Splicing Leading to Nonsense-Mediated Decay

Wollerton, M. C., Gooding, C., Wagner, E. J., Garcia-Blanco, M. A. & Smith, C. W. J., Jan 16 2004, In : Molecular cell. 13, 1, p. 91-100 10 p.

Research output: Contribution to journalArticle

278 Scopus citations

Biochemistry and Molecular Biology of Flaviviruses

Barrows, N. J., Campos, R. K., Liao, K. C., Kambham, R., Soto-Acosta, R., Yeh, S. C., Schott-Lerner, G., Pompon, J., Sessions, O. M., Bradrick, S. S. & Garcia-Blanco, M. A., Apr 25 2018, In : Chemical Reviews. 118, 8, p. 4448-4482 35 p.

Research output: Contribution to journalArticle

30 Scopus citations

Both phosphorylation and dephosphorylation of ASF/SF2 are required for pre-mRNA splicing in vitro

Cao, W., Jamison, S. F. & Garcia-Blanco, M. A., Dec 1 1997, In : RNA. 3, 12, p. 1456-1467 12 p.

Research output: Contribution to journalArticle

141 Scopus citations

CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription

Suñe, C., Hayashi, T., Liu, Y., Lane, W. S., Young, R. A. & Garcia-Blanco, M. A., Oct 1997, In : Molecular and Cellular Biology. 17, 10, p. 6029-6039 11 p.

Research output: Contribution to journalArticle

Open Access
80 Scopus citations

Canine cyclin T1 rescues equine infectious anemia virus tat trans- activation in human cells

Albrecht, T. R., Lund, L. H. & Garcia-Blanco, M. A., Mar 1 2000, In : Virology. 268, 1, p. 7-11 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Carcinosarcomas: Tumors in transition?

Somarelli, J. A., Boss, M. K., Epstein, J. I., Armstrong, A. J. & Garcia-Blanco, M., 2015, In : Histology and Histopathology. 30, 6, p. 673-687 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

Cellular migration and invasion uncoupled: Increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition

Schaeffer, D., Somarelli, J. A., Hanna, G., Palmer, G. M. & Garcia-Blanco, M. A., 2014, In : Molecular and cellular biology. 34, 18, p. 3486-3499 14 p.

Research output: Contribution to journalArticle

38 Scopus citations

Characterization of cDNAs encoding the polypyrimidine tract-binding protein

Gil, A., Sharp, P. A., Jamison, S. F. & Garcia-Blanco, M. A., Jul 1991, In : Genes and Development. 5, 7, p. 1224-1236 13 p.

Research output: Contribution to journalArticle

Open Access
214 Scopus citations

Characterization of the intronic splicing silencers flanking FGFR2 exon IIIb

Wagner, E. J., Baraniak, A. P., Sessions, O. M., Mauger, D., Moskowitz, E. & Garcia-Blanco, M. A., Apr 8 2005, In : Journal of Biological Chemistry. 280, 14, p. 14017-14027 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

Circulating tumor cells from patients with advanced prostate and breast cancer display both epithelial and mesenchymal markers

Armstrong, A. J., Marengo, M. S., Oltean, S., Kemeny, G., Bitting, R. L., Turnbull, J. D., Herold, C. I., Marcom, P. K., George, D. J. & Garcia-Blanco, M. A., Aug 1 2011, In : Molecular Cancer Research. 9, 8, p. 997-1007 11 p.

Research output: Contribution to journalArticle

421 Scopus citations

Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6

Evsyukova, I., Bradrick, S. S., Gregory, S. G. & Garcia-Blanco, M. A., Jan 1 2013, In : RNA. 19, 1, p. 103-115 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

Comparative loss-of-function screens reveal ABCE1 as an essential cellular host factor for efficient translation of paramyxoviridae and pneumoviridae

Anderson, D. E., Pfeffermann, K., Kim, S. Y., Sawatsky, B., Pearson, J., Kovtun, M., Corcoran, D. L., Krebs, Y., Sigmundsson, K., Jamison, S. F., Yeo, Z. Z. J., Rennick, L. J., Wang, L. F., Talbot, P. J., Duprex, W. P., Garcia-Blanco, M. A. & von Messling, V., May 1 2019, In : mBio. 10, 3, e00826-19.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Correction of tau mis-splicing caused by FTDP-17 MAPT mutations by spliceosome-mediated RNA trans-splicing

Rodriguez-Martin, T., Anthony, K., Garcia-Blanco, M. A., Mansfield, S. G., Anderton, B. H. & Gallo, J. M., Aug 20 2009, In : Human Molecular Genetics. 18, 17, p. 3266-3273 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Coupled in vitro synthesis and splicing of RNA polymerase II transcripts

Ghosh, S. & Garcia-Blanco, M. A., Oct 2 2000, In : RNA. 6, 9, p. 1325-1334 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission

Pompon, J., Manuel, M., Ng, G. K., Wong, B., Shan, C., Manokaran, G., Soto-Acosta, R., Bradrick, S. S., Ooi, E. E., Missé, D., Shi, P. Y. & Garcia-Blanco, M. A., Jul 2017, In : PLoS pathogens. 13, 7, e1006535.

Research output: Contribution to journalArticle

35 Scopus citations

Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness

Manokaran, G., Finol, E., Wang, C., Gunaratne, J., Bahl, J., Ong, E. Z., Tan, H. C., Sessions, O. M., Ward, A. M., Gubler, D. J., Harris, E., Garcia-Blanco, M. & Ooi, E. E., Oct 9 2015, In : Science. 350, 6257, p. 217-221 5 p.

Research output: Contribution to journalArticle

162 Scopus citations

Dengue virus selectively annexes endoplasmic reticulum-associated translation machinery as a strategy for co-opting host cell protein synthesis

Reid, D. W., Campos, R. K., Child, J. R., Zheng, T., Chan, K. W. K., Bradrick, S. S., Vasudevan, S. G., Garcia-Blanco, M. A. & Nicchitta, C. V., Apr 1 2018, In : Journal of virology. 92, 7, e01766-17.

Research output: Contribution to journalArticle

15 Scopus citations

Development of a method to isolate circulating tumor cells using mesenchymal-based capture

Bitting, R. L., Boominathan, R., Rao, C., Kemeny, G., Foulk, B., Garcia-Blanco, M. A., Connelly, M. & Armstrong, A. J., Dec 1 2013, In : Methods. 64, 2, p. 129-136 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Development of a novel c-MET-Based CTC detection platform

Zhang, T., Boominathan, R., Foulk, B., Rao, C., Kemeny, G., Strickler, J. H., Abbruzzese, J. L., Harrison, M. R., Hsu, D. S., Healy, P., Li, J., Pi, C., Prendergast, K. M., Hobbs, C., Gemberling, S., George, D. J., Hurwitz, H. I., Connelly, M., Garcia-Blanco, M. A. & Armstrong, A. J., Jun 2016, In : Molecular Cancer Research. 14, 6, p. 539-547 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Discovery of insect and human dengue virus host factors

Sessions, O. M., Barrows, N. J., Souza-Neto, J. A., Robinson, T. J., Hershey, C. L., Rodgers, M. A., Ramirez, J. L., Dimopoulos, G., Yang, P. L., Pearson, J. L. & Garcia-Blanco, M. A., Apr 23 2009, In : Nature. 458, 7241, p. 1047-1050 4 p.

Research output: Contribution to journalArticle

278 Scopus citations

Distinct routes to metastasis: Plasticity-dependent and plasticity-independent pathways

Somarelli, J. A., Schaeffer, D., Marengo, M. S., Bepler, T., Rouse, D., Ware, K. E., Hish, A. J., Zhao, Y., Buckley, A. F., Epstein, J. I., Armstrong, A. J., Virshup, D. M. & Garcia-Blanco, M., Aug 18 2016, In : Oncogene. 35, 33, p. 4302-4311 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis

Barrows, N. J., Anglero-Rodriguez, Y., Kim, B., Jamison, S. F., Le Sommer, C., McGee, C. E., Pearson, J. L., Dimopoulos, G., Ascano, M., Bradrick, S. S. & Garcia-Blanco, M. A., Dec 1 2019, In : Scientific reports. 9, 1, 9711.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
19 Scopus citations

Effect of human gamma interferon on yellow fever virus infection

Arroyo, J. I., Apperson, S. A., Cropp, C. B., Marafino, B. J., Monath, T. P., Tesh, R. B., Shope, R. E. & Garcia-Blanco, M. A., Jan 1 1988, In : American Journal of Tropical Medicine and Hygiene. 38, 3, p. 647-650 4 p.

Research output: Contribution to journalArticle

25 Scopus citations

Epstein-barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency

Homa, N. J., Salinas, R., Forte, E., Robinson, T. J., Garcia-Blanco, M. A. & Luftig, M. A., 2013, In : Journal of virology. 87, 22, p. 12291-12301 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Exon circularization in mammalian nuclear extracts

Pasman, Z., Been, M. D. & Garcia-Blanco, M. A., Nov 19 1996, In : RNA. 2, 6, p. 603-610 8 p.

Research output: Contribution to journalArticle

103 Scopus citations