Mark Hellmich, PhD

Program Director, Human Pathophysiology & Translational Medicine

  • 3970 Citations
  • 37 h-Index
1986 …2023
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  • 6 Similar Profiles
Cholecystokinin B Receptor Medicine & Life Sciences
Neurotensin Medicine & Life Sciences
Colonic Neoplasms Medicine & Life Sciences
Bombesin Medicine & Life Sciences
Bombesin Receptors Medicine & Life Sciences
Hydrogen Sulfide Medicine & Life Sciences
Cells Chemical Compounds
Cystathionine Medicine & Life Sciences

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Projects 2013 2023

Research Output 1986 2019

  • 3970 Citations
  • 37 h-Index
  • 101 Article
  • 1 Chapter
  • 1 Comment/debate

3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics

Abdollahi Govar, A., Törő, G., Szaniszlo, P., Pavlidou, A., Bibli, S. I., Thanki, K., Resto, V., Chao, C., Hellmich, M., Szabo, C., Papapetropoulos, A. & Modis, K., Jan 1 2019, In : British Journal of Pharmacology.

Research output: Contribution to journalArticle

Energy Metabolism
Endothelial Cells
Small Interfering RNA
Cell Movement
Gasotransmitters
1 Citation (Scopus)

Apigenin Decreases Acinar Cell Damage in Pancreatitis

Mrazek, A. A., Bhatia, V., Falzon, M., Spratt, H., Chao, C. & Hellmich, M., May 1 2019, In : Pancreas. 48, 5, p. 711-718 8 p.

Research output: Contribution to journalArticle

Apigenin
Acinar Cells
Pancreatitis
Parathyroid Hormone-Related Protein
Transforming Growth Factors
8 Citations (Scopus)

Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells

Untereiner, A. A., Pavlidou, A., Druzhyna, N., Papapetropoulos, A., Hellmich, M. & Szabo, C., 2017, (Accepted/In press) In : Biochemical Pharmacology.

Research output: Contribution to journalArticle

Drug Resistance
Fluorouracil
Colonic Neoplasms
Up-Regulation
Cells
13 Citations (Scopus)

H2S-induced S-sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells

Untereiner, A. A., Oláh, G., Modis, K., Hellmich, M. & Szabo, C., Feb 7 2017, (Accepted/In press) In : Biochemical Pharmacology.

Research output: Contribution to journalArticle

L-Lactate Dehydrogenase
Colonic Neoplasms
Energy Metabolism
Cells
HCT116 Cells
5 Citations (Scopus)

Patient-derived xenografts from colorectal carcinoma: A temporal and hierarchical study of murine stromal cell replacement

Chao, C., Widen, S., Wood, T., Zatarain, J. R., Johnson, P., Gajjar, A., Gomez, G., Qiu, S., Thompson, J., Spratt, H. & Hellmich, M., Jul 1 2017, In : Anticancer Research. 37, 7, p. 3405-3412 8 p.

Research output: Contribution to journalArticle

Stromal Cells
Heterografts
Colorectal Neoplasms
Nude Mice
Heterologous Transplantation