Research output per year
Research output per year
Research output
- 61 Article
- 1 - 50 out of 61 results
Search results
-
2024
Protein SUMOylation promotes cAMP-independent EPAC1 activation
Yang, W., Mei, F. C., Lin, W., White, M. A., Li, L., Li, Y., Pan, S. & Cheng, X., Dec 2024, In: Cellular and Molecular Life Sciences. 81, 1, 283.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Structural basis for cloverleaf RNA-initiated viral genome replication
Gottipati, K., Mcneme, S. C., Tipo, J., White, M. A. & Choi, K., Sep 8 2023, In: Nucleic acids research. 51, 16, p. 8850-8863 14 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
2022
Epac1 activation by cAMP regulates cellular SUMOylation and promotes the formation of biomolecular condensates
Yang, W., Robichaux, W. G., Mei, F. C., Lin, W., Li, L., Pan, S., White, M. A., Chen, Y. & Cheng, X., Apr 2022, In: Science Advances. 8, 16, eabm2960.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2021
Atomistic basis of force generation, translocation, and coordination in a viral genome packaging motor
Pajak, J., Dill, E., Reyes-Aldrete, E., White, M. A., Kelch, B. A., Jardine, P. J., Arya, G. & Morais, M., Jun 21 2021, In: Nucleic acids research. 49, 11, p. 6474-6488 15 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
A viral genome packaging motor transitions between cyclic and helical symmetry to translocate dsDNA
Woodson, M., Pajak, J., Mahler, B. P., Zhao, W., Zhang, W., Arya, G., White, M. A., Jardine, P. J. & Morais, M., May 2021, In: Science Advances. 7, 19, eabc1955.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Biochemical and biophysical characterization of the dsdna packaging motor from the lactococcus lactis bacteriophage asccphi28
Reyes-Aldrete, E., Dill, E. A., Bussetta, C., Szymanski, M. R., Diemer, G., Maindola, P., White, M. A., Bujalowski, W. M., Choi, K. H. & Morais, M. C., Jan 2021, In: Viruses. 13, 1, 15.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Signal Transmission in Escherichia coli Cyclic AMP Receptor Protein for Survival in Extreme Acidic Conditions
Evangelista, W., Knapp, J., Zandarashvili, L., Esadze, A., White, M. A., Gribenko, A. V. & Lee, J., Oct 12 2021, In: Biochemistry. 60, 40, p. 2987-3006 20 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
2020
A cocrystal structure of dengue capsid protein in complex of inhibitor
Xia, H., Xie, X., Zou, J., Noble, C. G., Russell, W. K., Holthauzen, L. M. F., Choi, K. H., White, M. A. & Shi, P. Y., Jul 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 30, p. 17992-18001 10 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Conformational states of exchange protein directly activated by camp (Epac1) revealed by ensemble modeling and integrative structural biology
White, M. A., Tsalkova, T., Mei, F. C. & Cheng, X., Jan 2020, In: Cells. 9, 1, 35.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Discovery of COVID-19 Inhibitors Targeting the SARS-CoV-2 Nsp13 Helicase
White, M. A., Lin, W. & Cheng, X., Nov 5 2020, In: Journal of Physical Chemistry Letters. 11, 21, p. 9144-9151 8 p.Research output: Contribution to journal › Article › peer-review
Open Access112 Scopus citations -
Discovery of phenanthridine analogues as novel chemical probes disrupting the binding of DNA to ΔFosB homodimers and ΔFosB/JunD heterodimers
Li, Y., Liu, Z., Aglyamova, G., Chen, J., Chen, H., Bhandari, M., White, M. A., Rudenko, G. & Zhou, J., Aug 15 2020, In: Bioorganic and Medicinal Chemistry Letters. 30, 16, 127300.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Mutational Analysis of the Structure and Function of the Chaperoning Domain of UNC-45B
Gaziova, I., Moncrief, T., Christian, C. J., Villarreal, M., Powell, S., Lee, H., Qadota, H., White, M. A., Benian, G. M. & Oberhauser, A. F., Aug 18 2020, In: Biophysical journal. 119, 4, p. 780-791 12 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Self-Assembly of Block Heterochiral Peptides into Helical Tapes
Clover, T. M., O'Neill, C. L., Appavu, R., Lokhande, G., Gaharwar, A. K., Posey, A. E., White, M. A. & Rudra, J. S., Nov 25 2020, In: Journal of the American Chemical Society. 142, 47Research output: Contribution to journal › Article › peer-review
Open Access64 Scopus citations -
Structural Energy Landscapes and Plasticity of the Microstates of Apo Escherichia coli cAMP Receptor Protein
Chkheidze, R., Evangelista, W., White, M. A., Yin, Y. W. & Lee, J., Feb 4 2020, In: Biochemistry. 59, 4, p. 460-470 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The Interplay between Molten Globules and Heme Disassociation Defines Human Hemoglobin Disassembly
Samuel, P. P., White, M. A., Ou, W. C., Case, D. A., Phillips, G. N. & Olson, J. S., Mar 24 2020, In: Biophysical journal. 118, 6, p. 1381-1400 20 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2019
Design, Synthesis, and Biological Evaluation of Substituted 4,6-Dihydrospiro[[1,2,3]triazolo[4,5- b]pyridine-7,3′-indoline]-2′,5(3 H)-dione Analogues as Potent NS4B Inhibitors for the Treatment of Dengue Virus Infection
Xu, J., Xie, X., Ye, N., Zou, J., Chen, H., White, M. A., Shi, P. Y. & Zhou, J., Sep 12 2019, In: Journal of medicinal chemistry. 62, 17, p. 7941-7960 20 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT 2C Receptor
Wild, C. T., Miszkiel, J. M., Wold, E. A., Soto, C. A., Ding, C., Hartley, R., White, M. A., Anastasio, N. C., Cunningham, K. A. & Zhou, J., Oct 1 2019, In: Journal of medicinal chemistry. 62, 1, p. 288-305 18 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Differential modulation of energy landscapes of cyclic AMP receptor protein (CRP) as a regulatory mechanism for class II CRP-dependent promoters
Evangelista, W., Dong, A., White, M. A., Li, J. & Ching Lee, J., Oct 18 2019, In: Journal of Biological Chemistry. 294, 42, p. 15544-15556 13 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2018
FerA is a Membrane-Associating Four-Helix Bundle Domain in the Ferlin Family of Membrane-Fusion Proteins
Harsini, F. M., Chebrolu, S., Fuson, K. L., White, M. A., Rice, A. M. & Sutton, R. B., Dec 1 2018, In: Scientific reports. 8, 1, 10949.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Functional Modulation of Voltage-Gated Sodium Channels by a FGF14-Based Peptidomimetic
Ali, S. R., Liu, Z., Nenov, M. N., Folorunso, O., Singh, A., Scala, F., Chen, H., James, T. F., Alshammari, M., Panova-Elektronova, N. I., White, M. A., Zhou, J. & Laezza, F., May 16 2018, In: ACS chemical neuroscience. 9, 5, p. 976-987 12 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Regio- and Stereospecific Synthesis of Oridonin D-Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent Warheads
Ding, Y., Li, D., Ding, C., Wang, P., Liu, Z., Wold, E. A., Ye, N., Chen, H., White, M. A., Shen, Q. & Zhou, J., Apr 12 2018, In: Journal of medicinal chemistry. 61, 7, p. 2737-2752 16 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Structural Plasticity of Neurexin 1α: Implications for its Role as Synaptic Organizer
Liu, J., Misra, A., Reddy, M. V. V. V. S., White, M. A., Ren, G. & Rudenko, G., Oct 19 2018, In: Journal of Molecular Biology. 430, 21, p. 4325-4343 19 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2017
A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease
Szymanski, M. R., Yu, W., Gmyrek, A. M., White, M. A., Molineux, I. J., Lee, J. C. & Yin, Y. W., 2017, In: Nature communications. 8, 14959.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Reversible stacking of lipid nanodiscs for structural studies of clotting factors
Grushin, K., White, M. A. & Stoilova-Mcphie, S., Feb 1 2017, In: Nanotechnology Reviews. 6, 1, p. 139-148 10 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2016
Molecular architecture of contactin-Associated protein-like 2 (CNTNAP2) and its interaction with contactin 2 (CNTN2)
Lu, Z., Reddy, M. V. V. V. S., Liu, J., Kalichava, A., Liu, J., Zhang, L., Chen, F., Wang, Y., Holthauzen, L. M. F., White, M. A., Seshadrinathan, S., Zhong, X., Ren, G. & Rudenko, G., Nov 11 2016, In: Journal of Biological Chemistry. 291, 46, p. 24133-24147 15 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein–DNA Affinity
Nguyen, D., Zandarashvili, L., White, M. A. & Iwahara, J., Sep 2 2016, In: ChemBioChem. p. 1636-1642 7 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
Jia, D., Zhang, J. S., Li, F., Wang, J., Deng, Z., White, M. A., Osborne, D. G., Phillips-Krawczak, C., Gomez, T. S., Li, H., Singla, A., Burstein, E., Billadeau, D. D. & Rosen, M. K., Nov 9 2016, In: Nature communications. 7, 13305.Research output: Contribution to journal › Article › peer-review
Open Access79 Scopus citations -
2015
Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate
Zandarashvili, L., Nguyen, D., Anderson, K. M., White, M. A., Gorenstein, D. G. & Iwahara, J., Sep 2 2015, In: Biophysical journal. 109, 5, p. 1026-1037 12 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1
Zandarashvili, L., White, M. A., Esadze, A. & Iwahara, J., Jul 3 2015, In: FEBS Letters. 589, 15, p. 1748-1753 6 p., 37178.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
2014
Ent-Kaurane-based regio- and stereoselective inverse electron demand hetero-Diels-Alder reactions: Synthesis of dihydropyran-fused diterpenoids
Ding, C., Wang, L., Chen, H., Wild, C., Ye, N., Ding, Y., Wang, T., White, M. A., Shen, Q. & Zhou, J., Nov 14 2014, In: Organic and Biomolecular Chemistry. 12, 42, p. 8442-8452 11 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Small-molecule Bax agonists for cancer therapy
Xin, M., Li, R., Xie, M., Park, D., Owonikoko, T. K., Sica, G. L., Corsino, P. E., Zhou, J., Ding, C., White, M. A., Magis, A. T., Ramalingam, S. S., Curran, W. J., Khuri, F. R. & Deng, X., 2014, In: Nature communications. 5, 4935.Research output: Contribution to journal › Article › peer-review
Open Access118 Scopus citations -
2013
Design of metastable β-sheet oligomers from natively unstructured peptide
Guerrero-Muñoz, M. J., Castillo-Carranza, D. L., Sengupta, U., White, M. A. & Kayed, R., Dec 18 2013, In: ACS chemical neuroscience. 4, 12, p. 1520-1523 4 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Efficient synthesis of ESI-09, a novel non-cyclic nucleotide EPAC antagonist
Chen, H., Ding, C., Wild, C., Liu, H., Wang, T., White, M. A., Cheng, X. & Zhou, J., Mar 20 2013, In: Tetrahedron Letters. 54, 12, p. 1546-1549 4 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Exonuclease of human DNA polymerase gamma disengages its strand displacement function
He, Q., Shumate, C. K., White, M. A., Molineux, I. J. & Yin, Y. W., Nov 2013, In: Mitochondrion. 13, 6, p. 592-601 10 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Oridonin ring A-based diverse constructions of enone functionality: Identification of novel dienone analogues effective for highly aggressive breast cancer by inducing apoptosis
Ding, C., Zhang, Y., Chen, H., Yang, Z., Wild, C., Ye, N., Ester, C. D., Xiong, A., White, M. A., Shen, Q. & Zhou, J., Nov 14 2013, In: Journal of medicinal chemistry. 56, 21, p. 8814-8825 12 p.Research output: Contribution to journal › Article › peer-review
Open Access78 Scopus citations -
Overcoming synthetic challenges of oridonin a-ring structural diversification: Regio- and stereoselective installation of azides and 1,2,3-triazoles at the c-1, c-2, or c-3 position
Ding, C., Zhang, Y., Chen, H., Wild, C., Wang, T., White, M. A., Shen, Q. & Zhou, J., Jul 19 2013, In: Organic Letters. 15, 14, p. 3718-3721 4 p.Research output: Contribution to journal › Article › peer-review
Open Access56 Scopus citations -
Preparation, characterization,and transport of dexamethasone-loaded polymeric nanoparticles across a human placental in vitro model
Ali, H., Kalashnikova, I., White, M. A., Sherman, M. & Rytting, E., 2013, In: International Journal of Pharmaceutics. 454, 1, p. 149-157 9 p.Research output: Contribution to journal › Article › peer-review
Open Access87 Scopus citations -
2012
Divergence of multimodular polyketide synthases revealed by a didomain structure
Zheng, J., Gay, D. C., Demeler, B., White, M. A. & Keatinge-Clay, A. T., Jul 2012, In: Nature Chemical Biology. 8, 7, p. 615-621 7 p.Research output: Contribution to journal › Article › peer-review
Open Access64 Scopus citations -
Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase
Lu, M., Huang, Y., White, M. A., Wu, X., Liu, N., Cheng, X. & Chen, Y., Oct 24 2012, In: Chemical Communications. 48, 92, p. 11352-11354 3 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Structural Analyses of a Constitutively Active Mutant of Exchange Protein Directly Activated by cAMP
White, M. A., Li, S., Tsalkova, T., Mei, F. C., Liu, T., Woods, V. L. & Cheng, X., Nov 26 2012, In: PloS one. 7, 11, e49932.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
2011
Mechanism of intracellular cAMP sensor Epac2 activation: cAMP-induced conformational changes identified by amide hydrogen/Deuterium Exchange Mass Spectrometry (DXMS)
Li, S., Tsalkova, T., White, M. A., Mei, F. C., Liu, T., Wang, D., Woods, V. L. & Cheng, X., May 20 2011, In: Journal of Biological Chemistry. 286, 20, p. 17889-17897 9 p.Research output: Contribution to journal › Article › peer-review
62 Scopus citations -
2010
Structural basis for substrate specificity of alphavirus nsP2 proteases
Russo, A. T., Malmstrom, R. D., White, M. A. & Watowich, S. J., Aug 2010, In: Journal of Molecular Graphics and Modelling. 29, 1, p. 46-53 8 p.Research output: Contribution to journal › Article › peer-review
39 Scopus citations -
2009
Mechanism of Epac activation. Structural and functional analyses of Epac2 hinge mutants with constitutive and reduced activities
Tsalkova, T., Blumenthal, D. K., Mei, F. C., White, M. A. & Cheng, X., Aug 28 2009, In: Journal of Biological Chemistry. 284, 35, p. 23644-23651 8 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
2008
Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain
Mast, N., White, M. A., Bjorkhem, I., Johnson, E. F., Stout, C. D. & Pikuleva, I. A., Jul 15 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 28, p. 9546-9551 6 p.Research output: Contribution to journal › Article › peer-review
Open Access110 Scopus citations -
Use of complementary cation and anion heavy-atom salt derivatives to solve the structure of cytochrome P450 46A1
White, M. A., Mast, N., Bjorkhem, I., Johnson, E. F., Stout, C. D. & Pikuleva, I. A., Apr 19 2008, In: Acta Crystallographica Section D: Biological Crystallography. 64, 5, p. 487-495 9 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
2007
Structural and thermodynamic consequences of 1-(4-chlorophenyl)imidazole binding to cytochrome P450 2B4
Zhao, Y., Sun, L., Muralidhara, B. K., Kumar, S., White, M. A., Stout, C. D. & Halpert, J. R., Oct 16 2007, In: Biochemistry. 46, 41, p. 11559-11567 9 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
2006
NMR solution structure and backbone dynamics of domain III of the E protein of tick-borne Langat flavivirus suggests a potential site for molecular recognition
Mukherjee, M., Dutta, K., White, M. A., Cowburn, D. & Fox, R. O., Jun 2006, In: Protein Science. 15, 6, p. 1342-1355 14 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Structure of a glutathione conjugate bound to the active site of aldose reductase
Singh, R., White, M. A., Ramana, K. V., Petrash, J. M., Watowich, S. J., Bhatnagar, A. & Srivastava, S. K., Jul 1 2006, In: Proteins: Structure, Function and Genetics. 64, 1, p. 101-110 10 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
Structure of microsomal cytochrome P450 2B4 complexed with the antifungal drug bifonazole: Insight into P450 conformational plasticity and membrane interaction
Zhao, Y., White, M. A., Muralidhara, B. K., Sun, L., Halpert, J. R. & Stout, C. D., Mar 3 2006, In: Journal of Biological Chemistry. 281, 9, p. 5973-5981 9 p.Research output: Contribution to journal › Article › peer-review
156 Scopus citations -
The crystal structure of the E. coli stress protein YciF
Hindupur, A., Liu, D., Zhao, Y., Bellamy, H. D., White, M. A. & Fox, R. O., 2006, In: Protein Science. 15, 11, p. 2605-2611 7 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations