Photo of Matthieu Gagnon

Matthieu Gagnon, PhD

  • 387 Citations
  • 10 h-Index
20002018
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Fingerprint Dive into the research topics where Matthieu Gagnon is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Ribosomes Medicine & Life Sciences
Peptide Elongation Factors Medicine & Life Sciences
Transfer RNA Medicine & Life Sciences
Ribosomal RNA Medicine & Life Sciences
Proteins Medicine & Life Sciences
Proline Medicine & Life Sciences
Peptides Medicine & Life Sciences
Peptide Elongation Factor G Medicine & Life Sciences

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Research Output 2000 2018

  • 387 Citations
  • 10 h-Index
  • 12 Article
  • 1 Editorial
  • 1 Review article
22 Citations (Scopus)

Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design

Lin, J., Zhou, D., Steitz, T. A., Polikanov, Y. S. & Gagnon, M., Jun 20 2018, In : Annual Review of Biochemistry. 87, p. 451-478 28 p.

Research output: Contribution to journalReview article

Drug Design
Ribosomes
Anti-Bacterial Agents
Protein Synthesis Inhibitors
Public health
10 Citations (Scopus)

Elongation factor 4 remodels the A-site tRNA on the ribosome

Gagnon, M., Lin, J. & Steitz, T. A., May 3 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 18, p. 4994-4999 6 p.

Research output: Contribution to journalArticle

Peptide Elongation Factors
Transfer RNA
Ribosomes
Guanosine Triphosphate
Peptidyl Transferases
44 Citations (Scopus)

Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition

Gagnon, M., Roy, R. N., Lomakin, I. B., Florin, T., Mankin, A. S. & Steitz, T. A., Jan 24 2016, In : Nucleic Acids Research. 44, 5, p. 2439-2450 12 p., 18.

Research output: Contribution to journalArticle

Ribosomes
Proline
Peptides
Proteins
Anti-Bacterial Agents

Antimicrobial peptides targeting bacterial ribosome

Lomakin, I. B., Gagnon, M. & Steitz, T. A., Jan 1 2015, In : Oncotarget. 6, 22, p. 18744-18745 2 p.

Research output: Contribution to journalEditorial

Antimicrobial Cationic Peptides
Microbial Drug Resistance
Ribosomes
Peptides
61 Citations (Scopus)

Conformational changes of elongation factor g on the ribosome during tRNA translocation

Lin, J., Gagnon, M., Bulkley, D. & Steitz, T. A., Jan 15 2015, In : Cell. 160, 1-2, p. 219-227 9 p.

Research output: Contribution to journalArticle

Peptide Elongation Factor G
Peptide Elongation Factors
Transfer RNA
Ribosomes
Conformations