Personal profile
Research Strategic Pillar
The Chief Research Officer, has determined that UTMB research should be prioritized into six health communities. This researcher has received the following badge(s):
Research Strategic Pillar Keywords
- Infectious/ Immunological Health
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Collaborations and top research areas from the last five years
Projects
- 3 Completed
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Mechanistic Function of HCV NS5A Targeted by Potent Inhibitors
National Institute of Allergy and Infectious Diseases ( Award #5R01AI14622705)
6/12/25 → 1/31/26
Project: Research project
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Mechanisms of HCV Assembly
Yi, M. K. (PI)
National Inst of Allergy & Infectious Di ( Award #5R01AI11035805)
3/1/15 → 2/28/22
Project: Research project
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Function of NS2 in Hepatitis C Virus Assembly and Release
Yi, M. K. (PI)
National Institute of Allergy and Infectious Diseases ( Award #5R01AI07509005)
9/1/08 → 8/31/14
Project: Research project
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Hepatitis C virus p7 regulates Core protein processing via signal peptide peptidase to promote virion assembly
Wu, M. J., Healy, P., Chang, C. W., Welsch, C. & Yi, M. K., May 2026, In: Journal of virology. 100, 5, e00288-26.Research output: Contribution to journal › Article › peer-review
Open Access -
Phospholipid-driven conformational switching of HCV NS5A links protein folding to replication membrane remodeling
Bulankina, A. V., Richter, R. M., Nettles, J. H., Yamane, D., Grimm, C., Karami, Y., Stanton, R. A., Introini, B., Hermann, J., Charif, H., König, M. S., Stroß, C., Ortiz, C., Kraus, N., Wood, D., Galceran, F., Abele, R., Maigret, B., Schinazi, R. F. & Zeuzem, S. & 5 others, , Apr 3 2026, In: Science Advances. 12, 14, eaeb8863.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
SPCS1-Dependent E2-p7 processing determines HCV Assembly efficiency
Alzahrani, N., Wu, M. J., Sousa, C. F., Kalinina, O. V., Welsch, C. & Yi, M. K., Feb 2022, In: PLoS pathogens. 18, 2, e1010310.Research output: Contribution to journal › Article › peer-review
Open Access6 Link opens in a new tab Scopus citations -
Delayed by design: Role of suboptimal signal peptidase processing of viral structural protein precursors in flaviviridae virus assembly
Alzahrani, N., Wu, M. J., Shanmugam, S. & Yi, M. K., Oct 2020, In: Viruses. 12, 10, 1090.Research output: Contribution to journal › Review article › peer-review
Open Access14 Link opens in a new tab Scopus citations -
Extended interaction networks with HCV protease NS3-4A substrates explain the lack of adaptive capability against protease inhibitors
Dultz, G., Shimakami, T., Schneider, M., Murai, K., Yamane, D., Marion, A., Zeitler, T. M., Stross, C., Grimm, C., Richter, R. M., Bäumer, K., Yi, M. K., Biondi, R. M., Zeuzem, S., Tampé, R., Antes, I., Lange, C. M. & Welsch, C., Oct 2 2020, In: Journal of Biological Chemistry. 295, 40, p. 13862-13874 13 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Link opens in a new tab Scopus citations