Projects per year
Personal profile
Personal profile
Division: Vaccinology
Dr. Bourne is a Professor in the Department of Pediatrics and Senior Scientist with the Sealy Center for Vaccine Development. He received his PhD from the University of Wales (Cardiff) Institute of Science and Technology. His research focus for over twenty years has been the development and evaluation of novel vaccines and therapeutics against viral infections with an emphasis on in vivo studies in appropriate small animal models. One of the principal areas of interest has been the development, refinement and use of mouse and guinea pig models of genital herpes disease to explore the impact of novel vaccines, antiviral agents and topical microbicides. In addition, for the past ten years he has worked extensively with small animal models of flavivirus diseases, in particular West Nile encephalitis, Japanese encephalitis and Dengue.
Research Strategic Pillar Keywords
- Infectious/ Immunological Health
Fingerprint
Dive into the research topics where Nigel Bourne is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 43 Completed
-
Baseline mapping of Oropouche virology, epidemiology, therapeutics, and vaccine research and development
Files, M. A., Hansen, C. A., Herrera, V. C., Schindewolf, C., Barrett, A. D. T., Beasley, D. W. C., Bourne, N. & Milligan, G. N., Dec 2022, In: npj Vaccines. 7, 1, 38.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Impact of yellow fever virus envelope protein on wild-type and vaccine epitopes and tissue tropism
Davis, E. H., Wang, B., White, M., Huang, Y. J. S., Sarathy, V. V., Wang, T., Bourne, N., Higgs, S. & Barrett, A. D. T., Dec 2022, In: npj Vaccines. 7, 1, 39.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Japanese encephalitis virus live attenuated vaccine strains display altered immunogenicity, virulence and genetic diversity
Davis, E. H., Beck, A. S., Li, L., White, M. M., Greenberg, M. B., Thompson, J. K., Widen, S. G., Barrett, A. D. T. & Bourne, N., Dec 2021, In: npj Vaccines. 6, 1, 112.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality
Maciejewski, S., Ruckwardt, T. J., Morabito, K. M., Foreman, B. M., Burgomaster, K. E., Gordon, D. N., Pelc, R. S., DeMaso, C. R., Ko, S. Y., Fisher, B. E., Yang, E. S., Nair, D., Foulds, K. E., Todd, J. P., Kong, W. P., Roy, V., Aleshnick, M., Speer, S. D., Bourne, N., Barrett, A. D., & 10 others, Jun 10 2020, In: Science Translational Medicine. 12, 547, eaaw9066.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses
Li, G., Adam, A., Luo, H., Shan, C., Cao, Z., Fontes-Garfias, C. R., Sarathy, V. V., Teleki, C., Winkelmann, E. R., Liang, Y., Sun, J., Bourne, N., Barrett, A. D. T., Shi, P. Y. & Wang, T., Dec 1 2019, In: npj Vaccines. 4, 1, 48.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations