Projects per year
Personal profile
Research Strategic Pillar
The Chief Research Officer, has determined that UTMB research should be prioritized into six health communities. This researcher has received the following badge(s):
Personal profile
Division: Vaccinology
Dr. Bourne is a Professor in the Department of Pediatrics and Senior Scientist with the Sealy Center for Vaccine Development. He received his PhD from the University of Wales (Cardiff) Institute of Science and Technology. His research focus for over twenty years has been the development and evaluation of novel vaccines and therapeutics against viral infections with an emphasis on in vivo studies in appropriate small animal models. One of the principal areas of interest has been the development, refinement and use of mouse and guinea pig models of genital herpes disease to explore the impact of novel vaccines, antiviral agents and topical microbicides. In addition, for the past ten years he has worked extensively with small animal models of flavivirus diseases, in particular West Nile encephalitis, Japanese encephalitis and Dengue.
Research Strategic Pillar Keywords
- Infectious/ Immunological Health
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Projects
- 7 Completed
-
HSV testing in animal models
Bourne, N. (PI)
Conrad ( Award #AIDOAAA1400010)
5/1/17 → 10/15/18
Project: Research project
-
The VesiVax System: Vaccine Development Made Easy
Bourne, N. (PI)
Molecular Express, Inc ( Award #2R44AI09477003A1)
8/1/16 → 7/31/18
Project: Research project
-
Zika Virus Recombinant Subunit Vaccine
Bourne, N. (PI)
Hawaii Biotech, Inc ( Award # )
7/1/16 → 6/1/17
Project: Research project
-
EL II: Engineering of a Novel CDN Nanoparticle Platform
Bourne, N. (PI)
Molecular Express, Inc ( Award #1R43AI11213201A1)
9/1/14 → 9/30/15
Project: Research project
-
-
Zika virus: advancing a priority research agenda for preparedness and response
Zika Expert Workgroup, 2025, (Accepted/In press) In: The Lancet Infectious Diseases.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
Zika virus vaccines and monoclonal antibodies: a priority agenda for research and development
Zika Expert Workgroup, 2025, (Accepted/In press) In: The Lancet Infectious Diseases.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
Efficacy of Polyphenylene Carboxymethylene (PPCM) Gel at Protecting Type I Interferon Receptors Knockout Mice from Intravaginal Ebola Virus Challenge
Escaffre, O., Juelich, T. L., Smith, J. K., Zhang, L., Pearson, M., Bourne, N. & Freiberg, A. N., Nov 2024, In: Viruses. 16, 11, 1693.Research output: Contribution to journal › Article › peer-review
Open Access -
Vaccine value profile for Chikungunya
Flandes, X., Hansen, C. A., Palani, S., Abbas, K., Bennett, C., Caro, W. P., Hutubessy, R., Khazhidinov, K., Lambach, P., Maure, C., Marshall, C., Rojas, D. P., Rosewell, A., Sahastrabuddhe, S., Tufet, M., Wilder-Smith, A., Beasley, D. W. C., Bourne, N. & Barrett, A. D. T., Jul 25 2024, In: Vaccine. 42, 19S1, p. S9-S24Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Blocking NS3–NS4B interaction inhibits dengue virus in non-human primates
Goethals, O., Kaptein, S. J. F., Kesteleyn, B., Bonfanti, J. F., Van Wesenbeeck, L., Bardiot, D., Verschoor, E. J., Verstrepen, B. E., Fagrouch, Z., Putnak, J. R., Kiemel, D., Ackaert, O., Straetemans, R., Lachau-Durand, S., Geluykens, P., Crabbe, M., Thys, K., Stoops, B., Lenz, O. & Tambuyzer, L. & 24 others, , Mar 23 2023, In: Nature. 615, 7953, p. 678-686 9 p.Research output: Contribution to journal › Article › peer-review
Open Access53 Scopus citations