• 3668 Citations
  • 35 h-Index
1992 …2020

Research output per year

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Research Output

  • 3668 Citations
  • 35 h-Index
  • 101 Article
  • 2 Chapter
  • 1 Comment/debate
  • 1 Review article
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Article

3,4-methylenedioxymethamphetamine increases susceptiblity to genital herpes simplex virus infection in mice

Pennock, J. W., Stegall, R., Bubar, M. J., Milligan, G., Cunningham, K. A. & Bourne, N., Oct 15 2009, In : Journal of Infectious Diseases. 200, 8, p. 1247-1250 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661

Furman, P. A., Murakami, E., Niu, C., Lam, A. M., Espiritu, C., Bansal, S., Bao, H., Tolstykh, T., Micolochick Steuer, H., Keilman, M., Zennou, V., Bourne, N., Veselenak, R. L., Chang, W., Ross, B. S., Du, J., Otto, M. J. & Sofia, M. J., Aug 2011, In : Antiviral research. 91, 2, p. 120-132 13 p.

Research output: Contribution to journalArticle

32 Scopus citations

A dengue virus type 4 model of disseminated lethal infection in AG129 mice

Milligan, G. N., Sarathy, V. V., Infante, E., Li, L., Campbell, G. A., Beatty, P. R., Harris, E., Barrett, A. D. T. & Bourne, N., May 4 2015, In : PloS one. 10, 5, e0125476.

Research output: Contribution to journalArticle

29 Scopus citations

A lethal model of disseminated dengue virus type 1 infection in AG129 mice

Milligan, G. N., Sarathy, V. V., White, M. M., Greenberg, M. B., Campbell, G. A., Pyles, R. B., Barrett, A. D. T. & Bourne, N., Oct 2017, In : Journal of General Virology. 98, 10, p. 2507-2519 13 p., 000923.

Research output: Contribution to journalArticle

7 Scopus citations
40 Scopus citations

An animal model of neonatal cytomegalovirus infection

Bravo, F. J., Bourne, N., Schleiss, M. R. & Bernstein, D. I., Sep 1 2003, In : Antiviral research. 60, 1, p. 41-49 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses

Li, G., Adam, A., Luo, H., Shan, C., Cao, Z., Fontes-Garfias, C. R., Sarathy, V. V., Teleki, C., Winkelmann, E. R., Liang, Y., Sun, J., Bourne, N., Barrett, A. D. T., Shi, P. Y. & Wang, T., Dec 1 2019, In : npj Vaccines. 4, 1, 48.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors

Shan, C., Xie, X., Muruato, A. E., Rossi, S. L., Roundy, C. M., Azar, S. R., Yang, Y., Tesh, R. B., Bourne, N., Barrett, A. D., Vasilakis, N., Weaver, S. C. & Shi, P. Y., Jun 8 2016, In : Cell Host and Microbe. 19, 6, p. 891-900 10 p.

Research output: Contribution to journalArticle

147 Scopus citations

Antibody-mediated protection against genital herpes simplex virus type 2 disease in mice by Fc gamma receptor-dependent and -independent mechanisms

Chu, C. F., Meador, M. G., Young, C. G., Strasser, J. E., Bourne, N. & Milligan, G. N., Jun 2008, In : Journal of Reproductive Immunology. 78, 1, p. 58-67 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Antiviral activity of geneticin against dengue virus

Zhang, X. G., Mason, P. W., Dubovi, E. J., Xu, X., Bourne, N., Renshaw, R. W., Block, T. M. & Birk, A. V., Jul 2009, In : Antiviral research. 83, 1, p. 21-27 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Antiviral profiles of novel iminocyclitol compounds against bovine viral diarrhea virus, West Nile virus, dengue virus and hepatitis B virus

Gu, B., Mason, P., Wang, L., Norton, P., Bourne, N., Moriarty, R., Mehta, A., Despande, M., Shah, R. & Block, T., Jan 1 2007, In : Antiviral Chemistry and Chemotherapy. 18, 1, p. 49-59 11 p.

Research output: Contribution to journalArticle

45 Scopus citations

Antiviral Suppression vs Restoration of RIG-I Signaling by Hepatitis C Protease and Polymerase Inhibitors

Liang, Y., Ishida, H., Lenz, O., Lin, T. I., Nyanguile, O., Simmen, K., Pyles, R. B., Bourne, N., Yi, M. K., Li, K. & Lemon, S. M., Nov 2008, In : Gastroenterology. 135, 5, p. 1710-1718.e2

Research output: Contribution to journalArticle

45 Scopus citations

Application of optical coherence tomography for monitoring changes in cervicovaginal epithelial morphology in Macaques: Potential for assessment of microbicide safety

Vincent, K. L., Bell, B. A., Rosenthal, S. L., Stanberry, L. R., Bourne, N., Sweeney, Y. T. C., Patton, D. L. & Motamedi, M., Mar 1 2008, In : Sexually Transmitted Diseases. 35, 3, p. 269-275 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Assessment of a selective inhibitor of herpes simplex virus thymidine kinase (L-653,180) as therapy for experimental recurrent genital herpes

Bourne, N., Bravo, F. J., Ashton, W. T., Meurer, L. C., Tolman, R. L., Karkas, J. D. & Stanberry, L. R., Jan 1 1992, In : Antimicrobial Agents and Chemotherapy. 36, 9, p. 2020-2024 5 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Attenuation of zika virus by passage in human HeLa cells

Li, L., Collins, N. D., Widen, S. G., Davis, E. H., Kaiser, J. A., White, M. M., Greenberg, M. B., Barrett, A. D. T., Bourne, N. & Sarathy, V. V., Sep 2019, In : Vaccines. 7, 3, 93.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

A Vaxfectin®-adjuvanted HSV-2 plasmid DNA vaccine is effective for prophylactic and therapeutic use in the guinea pig model of genital herpes

Veselenak, R. L., Shlapobersky, M., Pyles, R. B., Wei, Q., Sullivan, S. M. & Bourne, N., Nov 19 2012, In : Vaccine. 30, 49, p. 7046-7051 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

Benzalkonium chloride causes colposcopic changes and increased susceptibility to genital herpes infection in mice

Vincent, K. L., Bell, B. A., Johnston, R. K., Stegall, R., Vargas, G., Tan, A., Stanberry, L. R., Rosenthal, S. L., Milligan, G. N., Motamedi, M. & Bourne, N., Sep 1 2010, In : Sexually Transmitted Diseases. 37, 9, p. 579-584 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Bioluminescence methodology for the detection of protein-protein interactions within the voltage-gated sodium channel macromolecular complex

Shavkunov, A., Panova, N., Prasai, A., Veselenak, R., Bourne, N., Stoilova-McPhie, S. & Laezza, F., Apr 1 2012, In : Assay and Drug Development Technologies. 10, 2, p. 148-160 13 p.

Research output: Contribution to journalArticle

29 Scopus citations

Capsaicin‐sensitive peptidergic neurons are involved in the zosteriform spread of herpes simplex virus infection

Stanberry, L. R., Bourne, N., Bravo, F. J. & Bernstein, D. I., Oct 1992, In : Journal of Medical Virology. 38, 2, p. 142-146 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Characterization of a murine model of non-lethal, symptomatic dengue virus infection

Sarathy, V. V., White, M., Li, L., Kaiser, J. A., Campbell, G. A., Milligan, G. N., Bourne, N. & Barrett, A. D. T., Dec 1 2018, In : Scientific reports. 8, 1, 4900.

Research output: Contribution to journalArticle

9 Scopus citations
14 Scopus citations

Civamide (cis-capsaicin) for treatment of primary or recurrent experimental genital herpes

Bourne, N., Bernstein, D. I. & Stanberry, L. R., 1999, In : Antimicrobial agents and chemotherapy. 43, 11, p. 2685-2688 4 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Conjugation to nickel-chelating nanolipoprotein particles increases the potency and efficacy of subunit vaccines to prevent west nile encephalitis

Fischer, N. O., Infante, E., Ishikawa, T., Blanchette, C. D., Bourne, N., Hoeprich, P. D. & Mason, P. W., Jun 16 2010, In : Bioconjugate Chemistry. 21, 6, p. 1018-1022 5 p.

Research output: Contribution to journalArticle

29 Scopus citations

Construction and characterization of a replication-defective herpes simplex virus 2 ICP8 mutant strain and its use in immunization studies in a guinea pig model of genital disease

Da Costa, X. J., Bourne, N., Stanberry, L. R. & Knipe, D. M., May 26 1997, In : Virology. 232, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

70 Scopus citations

Construction and characterization of a second-generation pseudoinfectious West Nile virus vaccine propagated using a new cultivation system

Widman, D. G., Ishikawa, T., Fayzulin, R., Bourne, N. & Mason, P. W., May 23 2008, In : Vaccine. 26, 22, p. 2762-2771 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

Construction and evaluation of a chimeric pseudoinfectious virus vaccine to prevent Japanese encephalitis

Ishikawa, T., Widman, D. G., Bourne, N., Konishi, E. & Mason, P. W., May 23 2008, In : Vaccine. 26, 22, p. 2772-2781 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Cultivated human vaginal microbiome communities impact zika and herpes simplex virus replication in ex vivovaginal mucosal cultures

Amerson-Brown, M. H., Miller, A. L., Maxwell, C. A., White, M. M., Vincent, K. L., Bourne, N. & Pyles, R. B., 2019, In : Frontiers in Microbiology. 10, JAN, 3340.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Cyclic HPMPC is safe and effective against systemic guinea pig cytomegalovirus infection in immune compromised animals

Bourne, N., Bravo, F. J. & Bernstein, D. I., Aug 1 2000, In : Antiviral research. 47, 2, p. 103-109 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Dendrimers, a new class of candidate topical microbicides with activity against herpes simplex virus infection

Bourne, N., Stanberry, L. R., Kern, E. R., Holan, G., Matthews, B. & Bernstein, D. I., 2000, In : Antimicrobial agents and chemotherapy. 44, 9, p. 2471-2474 4 p.

Research output: Contribution to journalArticle

162 Scopus citations

Detection of herpes simplex virus type 2 (HSV-2) -specific cell-mediated immune responses in guinea pigs during latent HSV-2 genital infection

Perry, C. L., Banasik, B. N., Gorder, S. R., Xia, J., Auclair, S., Bourne, N. & Milligan, G., Dec 1 2016, In : Journal of Immunological Methods. 439, p. 1-7 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
7 Scopus citations

Development of an anti-guinea pig CD4 monoclonal antibody for depletion of CD4+ T cells in vivo

Banasik, B. N., Perry, C. L., Keith, C. A., Bourne, N., Schäfer, H. & Milligan, G. N., Nov 2019, In : Journal of Immunological Methods. 474, 112654.

Research output: Contribution to journalArticle

Development of disease and immunity at the genital epithelium following intrarectal inoculation of male guinea pigs with herpes simplex virus type 2

Bourne, N., Banasik, B. N., Perry, C. L., Miller, A. L., White, M., Pyles, R. B. & Milligan, G. N., Jan 2 2019, In : Virology. 526, p. 180-188 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Discovery of small molecule inhibitors of West Nile virus using a high-throughput sub-genomic replicon screen

Gu, B., Ouzunov, S., Wang, L., Mason, P., Bourne, N., Cuconati, A. & Block, T. M., Jun 1 2006, In : Antiviral research. 70, 2, p. 39-50 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality

Maciejewski, S., Ruckwardt, T. J., Morabito, K. M., Foreman, B. M., Burgomaster, K. E., Gordon, D. N., Pelc, R. S., DeMaso, C. R., Ko, S. Y., Fisher, B. E., Yang, E. S., Nair, D., Foulds, K. E., Todd, J. P., Kong, W. P., Roy, V., Aleshnick, M., Speer, S. D., Bourne, N., Barrett, A. D. & 10 others, Nason, M. C., Roederer, M., Gaudinski, M. R., Chen, G. L., Dowd, K. A., Ledgerwood, J. E., Alter, G., Mascola, J. R., Graham, B. S. & Pierson, T. C., Jun 10 2020, In : Science Translational Medicine. 12, 547, eaaw9066.

Research output: Contribution to journalArticle

DNA immunization against experimental genital herpes simplex virus infection

Bourne, N., Stanberry, L. R., Bernstein, D. I. & Lew, D., Jan 1 1996, In : Journal of Infectious Diseases. 173, 4, p. 800-807 8 p.

Research output: Contribution to journalArticle

Open Access
146 Scopus citations

DNA immunization confers protective immunity on mice challenged intravaginally with herpes simplex virus type 2

Bourne, N., Milligan, G. N., Schleiss, M. R., Bernstein, D. I. & Stanberry, L. R., Sep 1 1996, In : Vaccine. 14, 13, p. 1230-1234 5 p.

Research output: Contribution to journalArticle

81 Scopus citations
Open Access
19 Scopus citations

Early production of type I interferon during West Nile virus infection: Role for lymphoid tissues in IRF3-independent interferon production

Bourne, N., Scholle, F., Silva, M. C., Rossi, S. L., Dewsbury, N., Judy, B., De Aguiar, J. B., Leon, M. A., Estes, D. M., Fayzulin, R. & Mason, P. W., Sep 2007, In : Journal of virology. 81, 17, p. 9100-9108 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

Effect of antibody alone and combined with acyclovir on neonatal herpes simplex virus infection in guinea pigs

Bravo, F. J., Bourne, N., Harrison, C. J., Mani, C., Stanberry, L. R., Myers, M. G. & Bernstein, D. I., Jan 1 1996, In : Journal of Infectious Diseases. 173, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations

Effect of indomethacin on ultraviolet radiation-induced recurrent herpes simplex virus disease in guinea-pigs

Bratcher, D. F., Harrison, C. J., Bourne, N., Stanberry, L. R. & Bernstein, D. I., Jan 1 1993, In : Journal of General Virology. 74, 9, p. 1951-1954 4 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Effect of passive antibody on congenital cytomegalovirus infection in guinea pigs

Bratcher, D. F., Bourne, N., Bravo, F. J., Schleiss, M. R., Slaoui, M., Myers, M. G. & Bernstein, D. I., Oct 1995, In : Journal of Infectious Diseases. 172, 4, p. 944-950 7 p.

Research output: Contribution to journalArticle

72 Scopus citations

Effect of undecylenic acid as a topical microbicide against genital herpes infection in mice and guinea pigs

Bourne, N., Ireland, J., Stanberry, L. R. & Bernstein, D. I., Jan 1 1999, In : Antiviral research. 40, 3, p. 139-144 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

Efficacy and toxicity of zinc salts as candidate topical microbicides against vaginal herpes simplex virus type 2 infection

Bourne, N., Stegall, R., Montano, R., Meador, M., Stanberry, L. R. & Milligan, G. N., Mar 2005, In : Antimicrobial agents and chemotherapy. 49, 3, p. 1181-1183 3 p.

Research output: Contribution to journalArticle

25 Scopus citations

Enhancing the utility of a prM/E-expressing chimeric vaccine for Japanese encephalitis by addition of the JEV NS1 gene

Ishikawa, T., Wang, G., Widman, D. G., Infante, E., Winkelmann, E. R., Bourne, N. & Mason, P. W., Oct 6 2011, In : Vaccine. 29, 43, p. 7444-7455 12 p.

Research output: Contribution to journalArticle

15 Scopus citations
32 Scopus citations

Estradiol improves genital herpes vaccine efficacy in mice

Pennock, J. W., Stegall, R., Bell, B., Vargas, G., Motamedi, M., Milligan, G. & Bourne, N., Sep 25 2009, In : Vaccine. 27, 42, p. 5830-5836 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Evaluation of RepliVAX WN, a single-cycle flavivirus vaccine, in a non-human primate model of west nile virus infection

Widman, D. G., Ishikawa, T., Giavedoni, L. D., Hodara, V. L., De La Garza, M., Montalbo, J. A., Travassos Da Rosa, A. P., Tesh, R. B., Patterson, J. L., Carrion, R., Bourne, N. & Mason, P. W., Jun 2010, In : American Journal of Tropical Medicine and Hygiene. 82, 6, p. 1160-1167 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Evaluations of Unformulated and Formulated Dendrimer-Based Microbicide Candidates in Mouse and Guinea Pig Models of Genital Herpes

Bernstein, D. I., Stanberry, L. R., Sacks, S., Ayisi, N. K., Gong, Y. H., Ireland, J., Mumper, R. J., Holan, G., Matthews, B., McCarthy, T. & Bourne, N., Dec 2003, In : Antimicrobial agents and chemotherapy. 47, 12, p. 3784-3788 5 p.

Research output: Contribution to journalArticle

92 Scopus citations