Research output per year
Research output per year
- 1 - 50 out of 128 results
Search results
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2022
Animal Models of Trypanosoma cruzi Congenital Transmission
Avalos-Borges, E. E., Rios, L. E., Jiménez-Coello, M., Ortega-Pacheco, A. & Garg, N. J., Oct 2022, In: Pathogens. 11, 10, 1172.Research output: Contribution to journal › Review article › peer-review
Open Access -
Editorial: Protozoa and Their Hosts: An Oxidative Relationship
Menna-Barreto, R., Piacenza, L. & Garg, N. J., Feb 8 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 856191.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Platelets, Macrophages, and Thromboinflammation in Chagas Disease
Choudhuri, S. & Garg, N. J., 2022, In: Journal of Inflammation Research. 15, p. 5689-5706 18 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
2021
Heterogeneity in COVID-19 Patients at Multiple Levels of Granularity: From Biclusters to Clinical Interventions
Bhavnani, S. K., Kummerfeld, E., Zhang, W., Kuo, Y. F., Garg, N., Visweswaran, S., Raji, M., Radhakrishnan, R., Golvoko, G., Hatch, S., Usher, M., Melton-Meaux, G. & Tignanelli, C., 2021, In: AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. 2021, p. 112-121 10 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Mitochondrial Regulation of Macrophage Response Against Pathogens
Choudhuri, S., Chowdhury, I. H. & Garg, N. J., Feb 17 2021, In: Frontiers in immunology. 11, 622602.Research output: Contribution to journal › Review article › peer-review
Open Access10 Scopus citations -
Oxidative stress implications for therapeutic vaccine development against Chagas disease
Choudhuri, S., Rios, L., Vázquez-Chagoyán, J. C. & Garg, N. J., 2021, In: Expert review of vaccines. 20, 11, p. 1395-1406 12 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Poly(ADP-ribose) polymerase 1 regulates mitochondrial DNA repair in an NAD-dependent manner
Herrmann, G. K., Russell, W. K., Garg, N. J. & Yin, Y. W., Jan 1 2021, In: Journal of Biological Chemistry. 296, 100309.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Prognostic Performance of Peripheral Blood Biomarkers in Identifying Seropositive Individuals at Risk of Developing Clinically Symptomatic Chagas Cardiomyopathy
Choudhuri, S., Bhavnani, S. K., Zhang, W., Botelli, V., Barrientos, N., lñiguez, F., Zago, M. P. & Garg, N. J., Sep 2021, In: Microbiology Spectrum. 9, 1, p. 1-14 14 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
RBFOX2 is critical for maintaining alternative polyadenylation patterns and mitochondrial health in rat myoblasts
Cao, J., Verma, S., Jaworski, E., Mohan, S., Nagasawa, C. K., Rayavara, K., Sooter, A., Miller, S. N., Holcomb, R. J., Powell, M. J., Ji, P., Elrod, N., Yildirim, E., Wagner, E., Popov, V., Garg, N. J., Routh, A. L. & Kuyumcu-Martinez, M. N., Nov 2 2021, In: Cell Reports. 37, 5, 109910.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Sirtuin Control of Mitochondrial Dysfunction, Oxidative Stress, and Inflammation in Chagas Disease Models
Wan, X. & Garg, N. J., 2021, In: Frontiers in Cellular and Infection Microbiology. 11, p. 693051 1 p.Research output: Contribution to journal › Review article › peer-review
Open Access11 Scopus citations -
Trypanosoma cruzi co-infections with other vector borne diseases are frequent in dogs from the pacific coast of Ecuador
Rivadeneira-Barreiro, P. E., Montes de Oca-Jiménez, R., Vázquez-Chagoyán, J. C., Martínez-Subiela, S., Morán-Loor, A., Ochoa-García, L., Zambrano-Rodríguez, P. C., Garg, N. J. & Varela-Guerrero, J. A., Jun 2021, In: Microbial Pathogenesis. 155, 104884.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Use of a small molecule integrin activator as a systemically administered vaccine adjuvant in controlling Chagas disease
Lokugamage, N., Chowdhury, I. H., Biediger, R. J., Market, R. V., Khounlo, S., Warier, N. D., Hwang, S. A., Actor, J. K., Woodside, D. G., Marathi, U., Vanderslice, P. & Garg, N. J., Dec 2021, In: npj Vaccines. 6, 1, 114.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2020
Antigen-based nano-immunotherapy controls parasite persistence, inflammatory and oxidative stress, and cardiac fibrosis, the hallmarks of chronic chagas cardiomyopathy, in a mouse model of trypanosoma cruzi infection
Lokugamage, N., Choudhuri, S., Davies, C., Chowdhury, I. H. & Garg, N. J., Mar 2020, In: Vaccines. 8, 1, 96.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Epidemiology and pathogenesis of maternal-fetal transmission of Trypanosoma cruzi and a case for vaccine development against congenital Chagas disease
Rios, L., Campos, E. E., Menon, R., Zago, M. P. & Garg, N. J., Mar 1 2020, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 3, 165591.Research output: Contribution to journal › Review article › peer-review
Open Access17 Scopus citations -
Experimental Nanovaccine Offers Protection Against Repeat Exposures to Trypanosoma cruzi Through Activation of Polyfunctional T Cell Response
Chowdhury, I. H., Lokugamage, N. & Garg, N. J., Dec 22 2020, In: Frontiers in immunology. 11, 595039.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Genes of the cGMP-PKG-Ca2+ signaling pathway are alternatively spliced in cardiomyopathy: Role of RBFOX2
Wan, X., Belanger, K. A., Widen, S. G., Kuyumcu-Martinez, M. N. & Garg, N. J., Mar 1 2020, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 3, 165620.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Origin of monocytes/macrophages contributing to chronic inflammation in chagas disease: Sirt1 inhibition of fak-nfκb-dependent proliferation and proinflammatory activation of macrophages
Wan, X., Chowdhury, I. H., Jie, Z., Choudhuri, S. & Garg, N. J., Jan 2020, In: Cells. 9, 1, 80.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
PARP1-cGAS-NF-κB pathway of proinflammatory macrophage activation by extracellular vesicles released during Trypanosoma cruzi infection and Chagas disease
Choudhuri, S. & Garg, N. J., Apr 2020, In: PLoS pathogens. 16, 4, e1008474.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Potential Role of Antioxidants as Adjunctive Therapy in Chagas Disease
Sánchez-Villamil, J. P., Bautista-Ninõ, P. K., Serrano, N. C., Rincon, M. Y. & Garg, N. J., 2020, In: Oxidative medicine and cellular longevity. 2020, 9081813.Research output: Contribution to journal › Review article › peer-review
Open Access15 Scopus citations -
Trypanosoma cruzi induces the parp1/ap-1 pathway for upregulation of metalloproteinases and transforming growth factor β in macrophages: Role in cardiac fibroblast differentiation and fibrosis in chagas disease
Choudhuri, S. & Garg, N. J., Nov 1 2020, In: mBio. 11, 6, p. 1-18 18 p., e01853-20.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
2019
Atg5 supports Rickettsia australis infection in macrophages in vitro and in vivo
Bechelli, J., Vergara, L., Smalley, C., Buzhdygan, T. P., Bender, S., Zhang, W., Liu, Y., Popov, V. L., Wang, J., Garg, N., Hwang, S., Walker, D. H. & Fang, R., Jan 1 2019, In: Infection and immunity. 87, 1, e00651.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Fluorescence proteomic technology to analyze peripheral blood mononuclear cells in chronic chagas disease
Wiktorowicz, J. E., Zago, M. P. & Garg, N. J., 2019, Methods in Molecular Biology. Humana Press Inc., p. 363-380 18 p. (Methods in Molecular Biology; vol. 1955).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Immunity and vaccine development efforts against Trypanosoma cruzi
Rios, L. E., Vázquez-Chagoyán, J. C., Pacheco, A. O., Zago, M. P. & Garg, N. J., Dec 2019, In: Acta Tropica. 200, 105168.Research output: Contribution to journal › Review article › peer-review
Open Access35 Scopus citations -
Integrated functional analysis of the nuclear proteome of classically and alternatively activated macrophages
Wiktorowicz, J. E., Chowdhury, I. H., Stafford, S., Choudhuri, S., Dey, N. & Garg, N. J., 2019, In: Mediators of inflammation. 2019, 3481430.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Metabolic programming of macrophage functions and pathogens control
Koo, S. J. & Garg, N. J., Jun 2019, In: Redox Biology. 24, 101198.Research output: Contribution to journal › Review article › peer-review
Open Access54 Scopus citations -
Pathology and Pathogenesis of Chagas Heart Disease
Bonney, K. M., Luthringer, D. J., Kim, S. A., Garg, N. J. & Engman, D. M., 2019, In: Annual Review of Pathology: Mechanisms of Disease. 14, p. 421-447 27 p.Research output: Contribution to journal › Review article › peer-review
99 Scopus citations -
Potential utility of protein targets of cysteine-s-nitrosylation in identifying clinical disease status in human chagas disease
Zago, M. P., Wiktorowicz, J. E., Spratt, H., Koo, S. J., Barrientos, N., Burgos, A. N., Burgos, J. N., Iñiguez, F., Botelli, V., De La Fuente, R. L. & Garg, N. J., 2019, In: Frontiers in Microbiology. 10, JAN, 3320.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Redox Balance Keepers and Possible Cell Functions Managed by Redox Homeostasis in Trypanosoma cruzi
Mesías, A. C., Garg, N. J. & Zago, M. P., Dec 20 2019, In: Frontiers in Cellular and Infection Microbiology. 9, 435.Research output: Contribution to journal › Review article › peer-review
Open Access26 Scopus citations -
TcG2/TcG4 DNA Vaccine Induces Th1 Immunity against Acute Trypanosoma cruzi Infection: Adjuvant and antigenic effects of heterologous T. Rangeli Booster Immunization
Gupta, S., Salgado-Jiménez, B., Lokugamage, N., Vázquez-Chagoyán, J. C. & Garg, N. J., 2019, In: Frontiers in immunology. 10, JUN, 1456.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
TcVac1 vaccine delivery by intradermal electroporation enhances vaccine induced immune protection against Trypanosoma cruzi infection in mice
Hegazy-Hassan, W., Zepeda-Escobar, J. A., Ochoa-García, L., Contreras-Ortíz, J. M. E., Tenorio-Borroto, E., Barbabosa-Pliego, A., Aparicio-Burgos, J. E., Oros-Pantoja, R., Rivas-Santiago, B., Díaz-Albiter, H., Garg, N. J. & Vázquez-Chagoyán, J. C., Jan 7 2019, In: Vaccine. 37, 2, p. 248-257 10 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Trypanothione synthetase confers growth, survival advantage and resistance to anti-protozoal drugs in Trypanosoma cruzi
Mesías, A. C., Sasoni, N., Arias, D. G., Pérez Brandán, C., Orban, O. C. F., Kunick, C., Robello, C., Comini, M. A., Garg, N. J. & Zago, M. P., Jan 2019, In: Free Radical Biology and Medicine. 130, p. 23-34 12 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
2018
Early Trypanosoma cruzi infection triggers mTORC1-mediated respiration increase and mitochondrial biogenesis in human primary cardiomyocytes
Libisch, M. G., Faral-Tello, P., Garg, N. J., Radi, R., Piacenza, L. & Robello, C., Aug 16 2018, In: Frontiers in Microbiology. 9, AUG, 1889.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Efficacy of recombinase polymerase amplification to diagnose trypanosoma cruzi infection in dogs with cardiac alterations from an endemic Area of Mexico
Jimenez-Coello, M., Shelite, T., Castellanos-Gonzalez, A., Saldarriaga, O., Rivero, R., Ortega-Pacheco, A., Acevedo-Arcique, C., Amaya-Guardia, K., Garg, N., Melby, P. & Travi, B. L., Aug 1 2018, In: Vector-Borne and Zoonotic Diseases. 18, 8, p. 417-423 7 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Manganese superoxide dismutase deficiency exacerbates the mitochondrial ROS production and oxidative damage in Chagas disease
Wen, J. & Garg, N. J., Jul 25 2018, In: PLoS neglected tropical diseases. 12, 7, e0006687.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance
Wen, J., Yin, Y. W. & Garg, N. J., May 2018, In: PLoS pathogens. 14, 5, e1007065.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Pathogenesis of Chronic Chagas Disease: Macrophages, Mitochondria, and Oxidative Stress
Lopez, M., Tanowitz, H. B. & Garg, N. J., Mar 1 2018, In: Current Clinical Microbiology Reports. 5, 1, p. 45-54 10 p.Research output: Contribution to journal › Review article › peer-review
39 Scopus citations -
Pentose phosphate shunt modulates reactive oxygen species and nitric oxide production controlling Trypanosoma cruzi in Macrophages
Koo, S. J., Szczesny, B., Wan, X., Putluri, N. & Garg, N. J., Feb 16 2018, In: Frontiers in immunology. 9, FEB, 202.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Proinflammatory effects of respiratory syncytial virus-induced epithelial HMGB1 on human innate immune cell activation
Rayavara, K., Kurosky, A., Stafford, S. J., Garg, N. J., Brasier, A., Garofalo, R. P. & Hosakote Madaiah, Y., Nov 1 2018, In: Journal of Immunology. 201, 9, p. 2832-2841 10 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Quantitative and histological assessment of maternal-fetal transmission of Trypanosoma cruzi in guinea pigs: An experimental model of congenital Chagas disease
Torres-Vargas, J., Jiménez-Coello, M., Guzmán-Marín, E., Acosta-Viana, K. Y., Yadon, Z. E., Gutiérrez-Blanco, E., Guillermo-Cordero, J. L., Garg, N. J. & Ortega-Pacheco, A., Jan 2018, In: PLoS neglected tropical diseases. 12, 1, e0006222.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2017
Gene Expression Profiling and Functional Characterization of Macrophages in Response to Circulatory Microparticles Produced during Trypanosoma cruzi Infection and Chagas Disease
Chowdhury, I. H., Koo, S. J., Gupta, S., Liang, L. Y., Bahar, B., Silla, L., Nuñez-Burgos, J., Barrientos, N., Zago, M. P. & Garg, N. J., Feb 1 2017, In: Journal of Innate Immunity. 9, 2, p. 203-216 14 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Inhibition of NFE2L2-Antioxidant Response Element Pathway by Mitochondrial Reactive Oxygen Species Contributes to Development of Cardiomyopathy and Left Ventricular Dysfunction in Chagas Disease
Wen, J., Porter, C. & Garg, N. J., Sep 20 2017, In: Antioxidants and Redox Signaling. 27, 9, p. 550-566 17 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Protein Cysteinyl-S-Nitrosylation: Analysis and Quantification
Wiktorowicz, J. E., Stafford, S. J. & Garg, N. J., 2017, Methods in Enzymology. Academic Press Inc., Vol. 586. p. 1-14 14 p. (Methods in Enzymology; vol. 586).Research output: Chapter in Book/Report/Conference proceeding › Chapter
8 Scopus citations -
2016
Changes in Proteome Profile of Peripheral Blood Mononuclear Cells in Chronic Chagas Disease
Garg, N. J., Soman, K. V., Zago, M. P., Koo, S. J., Spratt, H., Stafford, S., Blell, Z. N., Gupta, S., Nuñez Burgos, J., Barrientos, N., Brasier, A. R. & Wiktorowicz, J. E., Feb 26 2016, In: PLoS neglected tropical diseases. 10, 2, e0004490.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Chemotherapeutic Efficacy of Phosphodiesterase Inhibitors in Chagasic Cardiomyopathy
Wen, J., Wan, X., Thacker, J. & Garg, N. J., Jun 1 2016, In: JACC: Basic to Translational Science. 1, 4, p. 235-250 16 p.Research output: Contribution to journal › Review article › peer-review
Open Access15 Scopus citations -
Differential inflammasome activation signatures following intracellular infection of human macrophages with Mycobacterium bovis BCG or Trypanosoma cruzi
Huante, M. B., Gupta, S., Calderon, V. C., Koo, S. J., Sinha, M., Luxon, B. A., Garg, N. J. & Endsley, J. J., Dec 1 2016, In: Tuberculosis. 101, p. S35-S44Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes
Nutter, C. A., Jaworski, E. A., Verma, S. K., Deshmukh, V., Wang, Q., Botvinnik, O. B., Lozano, M. J., Abass, I. J., Ijaz, T., Brasier, A. R., Garg, N. J., Wehrens, X. H. T., Yeo, G. W. & Kuyumcu-Martinez, M. N., Jun 7 2016, In: Cell Reports. 15, 10, p. 2200-2213 14 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Editorial commentary: Targeting Chagas disease
Tanowitz, H. B. & Garg, N., 2016, (Accepted/In press) In: Trends in Cardiovascular Medicine.Research output: Contribution to journal › Article › peer-review
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Macrophages promote oxidative metabolism to drive nitric oxide generation in response to Trypanosoma cruzi
Koo, S. J., Chowdhury, I. H., Szczesny, B., Wan, X. & Garg, N. J., 2016, In: Infection and immunity. 84, 12, p. 3527-3541 15 p.Research output: Contribution to journal › Article › peer-review
39 Scopus citations -
SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease
Wan, X., Wen, J., Koo, S. J., Liang, L. Y. & Garg, N. J., Oct 2016, In: PLoS pathogens. 12, 10, e1005954.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
S-Nitrosylation Proteome Profile of Peripheral Blood Mononuclear Cells in Human Heart Failure
Koo, S. J., Spratt, H. M., Soman, K. V., Stafford, S., Gupta, S., Petersen, J. R., Zago, M. P., Kuyumcu-Martinez, M. N., Brasier, A. R., Wiktorowicz, J. E. & Garg, N. J., 2016, In: International Journal of Proteomics. 2016, 1384523.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations