Research output per year
Research output per year
- 41 results
Search results
-
2024
Combination Immunotherapy with Vaccine and Oncolytic HSV Virotherapy Is Time Dependent
Totsch, S. K., Ishizuka, A. S., Kang, K. D., Gary, S. E., Rocco, A., Fan, A. E., Zhou, L., Valdes, P. A., Lee, S. H., Li, J., Peruzzotti-Jametti, L., Blitz, S., Garliss, C. M., Johnston, J. M., Markert, J. M., Lynn, G. M., Bernstock, J. D. & Friedman, G. K., Sep 1 2024, In: Molecular Cancer Therapeutics. 23, 9, p. 1273-1281 9 p.Research output: Contribution to journal › Article › peer-review
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Improved immunostaining of nanostructures and cells in human brain specimens through expansion-mediated protein decrowding
Valdes, P. A., Yu, C. C., Aronson, J., Ghosh, D., Zhao, Y., An, B., Bernstock, J. D., Bhere, D., Felicella, M. M., Viapiano, M. S., Shah, K., Chiocca, E. A. & Boyden, E. S., Jan 31 2024, In: Science Translational Medicine. 16, 732, p. eabo0049 eabo0049.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Inefficient tissue immune response against MPXV in an immunocompromised mpox patient
Matschke, J., Hartmann, K., Pfefferle, S., Wang, Y., Valdes, P. A., Thies, E., Schweizer, M., Lütgehetmann, M., Schmiedel, S., Bernreuther, C., Boyden, E. S., Glatzel, M. & Krasemann, S., Jul 2024, In: Journal of Medical Virology. 96, 7, p. e29811 e29811.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
The first neurosurgical service in Texas: neurosurgery at the University of Texas Medical Branch (1937–2023)
Valdés, P. A., Husain, A., Alonzo, A., Price, A., Nia, A. M., Maynard, K., Costa, M., Karas, P., Lall, R. R., Briner, R. P. & Kan, P., Oct 2024, In: Journal of neurosurgery. 141, 4, p. 1124-1132 9 p.Research output: Contribution to journal › Article › peer-review
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2023
Challenges in, and recommendations for, hyperspectral imaging in ex vivo malignant glioma biopsy measurements
Walke, A., Black, D., Valdes, P. A., Stummer, W., König, S. & Suero-Molina, E., Mar 7 2023, In: Scientific reports. 13, 1, p. 3829 3829.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Development of an educational method to rethink and learn oncological brain surgery in an “a la carte” connectome-based perspective
Valdes, P. A., Ng, S., Bernstock, J. D. & Duffau, H., Sep 2023, In: Acta Neurochirurgica. 165, 9, p. 2489-2500 12 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Intraoperative functional remapping unveils evolving patterns of cortical plasticity
Ng, S., Valdes, P. A., Moritz-Gasser, S., Lemaitre, A. L., Duffau, H. & Herbet, G., Jul 1 2023, In: Brain. 146, 7, p. 3088-3100 13 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
2022
Target receptor identification and subsequent treatment of resected brain tumors with encapsulated and engineered allogeneic stem cells
Bhere, D., Choi, S. H., van de Donk, P., Hope, D., Gortzak, K., Kunnummal, A., Khalsa, J., Revai Lechtich, E., Reinshagen, C., Leon, V., Nissar, N., Bi, W. L., Feng, C., Li, H., Zhang, Y. S., Liang, S. H., Vasdev, N., Essayed, W. I., Quevedo, P. V. & Golby, A. & 13 others, , Dec 2022, In: Nature communications. 13, 1, 2810.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2020
Characterizing the heterogeneity in 5-aminolevulinic acid-induced fluorescence in glioblastoma
Bonnin, D. A. A., Havrda, M. C., Lee, M. C., Evans, L., Ran, C., Qian, D. C., Harrington, L. X., Valdes, P. A., Cheng, C., Amos, C. I., Harris, B. T., Paulsen, K. D., Roberts, D. W. & Israel, M. A., Jun 2020, In: Journal of neurosurgery. 132, 6, p. 1706-1714 9 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Design and Rationale for First-in-Human Phase 1 Immunovirotherapy Clinical Trial of Oncolytic HSV G207 to Treat Malignant Pediatric Cerebellar Brain Tumors
Bernstock, J. D., Bag, A. K., Fiveash, J., Kachurak, K., Elsayed, G., Chagoya, G., Gessler, F., Valdes, P. A., Madan-Swain, A., Whitley, R., Markert, J. M., Gillespie, G. Y., Johnston, J. M. & Friedman, G. K., Oct 2020, In: Human Gene Therapy. 31, 19-20, p. 1132-1139 8 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Spatial Multiplexing of Fluorescent Reporters for Imaging Signaling Network Dynamics
Linghu, C., Johnson, S. L., Valdes, P. A., Shemesh, O. A., Park, W. M., Park, D., Piatkevich, K. D., Wassie, A. T., Liu, Y., An, B., Barnes, S. A., Celiker, O. T., Yao, C. C., Yu, C. C., Wang, R., Adamala, K. P., Bear, M. F., Keating, A. E. & Boyden, E. S., Dec 10 2020, In: Cell. 183, 6, p. 1682-1698.e24Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
2019
A novel in situ multiplex immunofluorescence panel for the assessment of tumor immunopathology and response to virotherapy in pediatric glioblastoma reveals a role for checkpoint protein inhibition
Bernstock, J. D., Vicario, N., Rong, L., Valdes, P. A., Choi, B. D., Chen, J. A., DiToro, D., Osorio, D. S., Kachurak, K., Gessler, F., Johnston, J. M., Atkinson, T. P., Whitley, R. J., Bag, A. K., Gillespie, G. Y., Markert, J. M., Maric, D. & Friedman, G. K., Dec 2 2019, In: OncoImmunology. 8, 12, e1678921.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
2018
Focused ultrasound in neurosurgery: A historical perspective
Harary, M., Segar, D. J., Huang, K. T., Tafel, I. J., Valdes, P. A. & Cosgrove, G. R., 2018, In: Neurosurgical focus. 44, 2, E2.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
Volumetric analysis of magnetic resonance-guided focused ultrasound thalamotomy lesions
Harary, M., Essayed, W. I., Valdes, P. A., McDannold, N. & Cosgrove, G. R., 2018, In: Neurosurgical focus. 44, 2, E6.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
2017
QF-SSOP: Real-time optical property corrected fluorescence imaging
Valdes, P. A., Angelo, J. P., Choi, H. S. & Gioux, S., Aug 1 2017, In: Biomedical Optics Express. 8, 8, p. 3597-3605 9 p., #295940.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Readmission after craniotomy for tumor: A national surgical quality improvement program analysis
Dasenbrock, H. H., Yan, S. C., Smith, T. R., Valdes, P. A., Gormley, W. B., Claus, E. B. & Dunn, I. F., Apr 1 2017, In: Clinical Neurosurgery. 80, 4, p. 551-562 12 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
2016
Optical technologies for intraoperative neurosurgical guidance
Valdés, P. A., Roberts, D. W., Lu, F. K. & Golby, A., Mar 1 2016, In: Neurosurgical focus. 40, 3, E8.Research output: Contribution to journal › Article › peer-review
Open Access105 Scopus citations -
2015
Improved sensitivity to fluorescence for cancer detection in wide-field image-guided neurosurgery
Jermyn, M., Gosselin, Y., Valdes, P. A., Sibai, M., Kolste, K., Mercier, J., Angulo, L., Roberts, D. W., Paulsen, K. D., Petrecca, K., Daigle, O., Wilson, B. C. & Leblond, F., Nov 30 2015, In: Biomedical Optics Express. 6, 12, p. 5063-5074 12 p., 252150.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Macroscopic optical imaging technique for wide-field estimation of fluorescence depth in optically turbid media for application in brain tumor surgical guidance
Kolste, K. K., Kanick, S. C., Valdés, P. A., Jermyn, M., Wilson, B. C., Roberts, D. W., Paulsen, K. D. & Leblond, F., Feb 1 2015, In: Journal of Biomedical Optics. 20, 2, 026002.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Quantitative fluorescence using 5-aminolevulinic acid-induced protoporphyrin IX biomarker as a surgical adjunct in low-grade glioma surgery
Valdés, P. A., Jacobs, V., Harris, B. T., Wilson, B. C., Leblond, F., Paulsen, K. D. & Roberts, D. W., Sep 2015, In: Journal of neurosurgery. 123, 3, p. 771-780 10 p.Research output: Contribution to journal › Article › peer-review
Open Access141 Scopus citations -
2013
Pulsed-light imaging for fluorescence guided surgery under normal room lighting
Sexton, K., Davis, S. C., McClatchy, D., Valdes, P. A., Kanick, S. C., Paulsen, K. D., Roberts, D. W. & Pogue, B. W., Sep 1 2013, In: Optics Letters. 38, 17, p. 3249-3252 4 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
System and methods for wide-field quantitative fluorescence imaging during neurosurgery
Valdes, P. A., Jacobs, V. L., Wilson, B. C., Leblond, F., Roberts, D. W. & Paulsen, K. D., Aug 1 2013, In: Optics Letters. 38, 15, p. 2786-2788 3 p.Research output: Contribution to journal › Article › peer-review
57 Scopus citations -
2012
Adjuncts for maximizing resection: 5-Aminolevuinic acid
Roberts, D. W., Valdés, P. A., Harris, B. T., Hartov, A., Fan, X., Ji, S., Pogue, B. W., Leblond, F., Tosteson, T. D., Wilson, B. C. & Paulsen, K. D., 2012, In: Clinical Neurosurgery. 59, p. 75-78 4 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
A spectrally constrained dual-band normalization technique for protoporphyrin IX quantification in fluorescence-guided surgery
Valdés, P. A., Leblond, F., Kim, A., Wilson, B. C., Paulsen, K. D. & Roberts, D. W., Jun 1 2012, In: Optics Letters. 37, 11, p. 1817-1819 3 p.Research output: Contribution to journal › Article › peer-review
Open Access56 Scopus citations -
Gadolinium-and 5-aminolevulinic acid-induced protoporphyrin IX levels in human gliomas: An ex vivo quantitative study to correlate protoporphyrin IX levels and blood-brain barrier breakdown
Valdés, P. A., Moses, Z. B., Kim, A., Belden, C. J., Wilson, B. C., Paulsen, K. D., Roberts, D. W. & Harris, B. T., Sep 2012, In: Journal of Neuropathology and Experimental Neurology. 71, 9, p. 806-813 8 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Quantitative, spectrally-resolved intraoperative fluorescence imaging
Valdés, P. A., Leblond, F., Jacobs, V. L., Wilson, B. C., Paulsen, K. D. & Roberts, D. W., 2012, In: Scientific reports. 2, 798.Research output: Contribution to journal › Article › peer-review
Open Access106 Scopus citations -
Spatial frequency domain tomography of protoporphyrin IX fluorescence in preclinical glioma models
Konecky, S. D., Owen, C. M., Rice, T., Valdés, P. A., Kolste, K., Wilson, B. C., Leblond, F., Roberts, D. W., Paulsen, K. D. & Tromberg, B. J., May 2012, In: Journal of Biomedical Optics. 17, 5, 056008.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
2011
Analytic expression of fluorescence ratio detection correlates with depth in multi-spectral sub-surface imaging
Leblond, F., Ovanesyan, Z., Davis, S. C., Valdés, P. A., Kim, A., Hartov, A., Wilson, B. C., Pogue, B. W., Paulsen, K. D. & Roberts, D. W., Nov 7 2011, In: Physics in Medicine and Biology. 56, 21, p. 6823-6837 15 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Combined fluorescence and reflectance spectroscopy for in vivo quantification of cancer biomarkers in low- and high-grade glioma surgery
Valdés, P. A., Kim, A., Leblond, F., Conde, O. M., Harris, B. T., Paulsen, K. D., Wilson, B. C. & Roberts, D. W., Nov 2011, In: Journal of Biomedical Optics. 16, 11, 116007.Research output: Contribution to journal › Article › peer-review
Open Access124 Scopus citations -
Confocal microscopy for the histological fluorescence pattern of a recurrent atypical meningioma: Case report
Whitson, W. J., Valdes, P. A., Harris, B. T., Paulsen, K. D. & Roberts, D. W., Jun 2011, In: Neurosurgery. 68, 6, p. E1768-E1772Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Coregistered fluorescence-enhanced tumor resection of malignant glioma: Relationships between δ-aminolevulinic acid-induced protoporphyrin IX fluorescence, magnetic resonance imaging enhancement, and neuropathological parameters: Clinical article
Roberts, D. W., Valdés, P. A., Harris, B. T., Fontaine, K. M., Hartov, A., Fan, X., Ji, S., Lollis, S. S., Pogue, B. W., Leblond, F., Tosteson, T. D., Wilson, B. C. & Paulsen, K. D., Mar 2011, In: Journal of neurosurgery. 114, 3, p. 595-603 9 p.Research output: Contribution to journal › Article › peer-review
Open Access241 Scopus citations -
Genetics of glioblastoma: A window into its imaging and histopathologic variability
Belden, C. J., Valdes, P. A., Ran, C., Pastel, D. A., Harris, B. T., Fadul, C. E., Israel, M. A., Paulsen, K. & Roberts, D. W., Oct 2011, In: Radiographics. 31, 6, p. 1717-1740 24 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
Quantitative and qualitative 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in skull base meningiomas
Bekelis, K., Valdés, P. A., Erkmen, K., Leblond, F., Kim, A., Wilson, B. E., Larris, B. T., Paulsen, K. D. & Roberts, D. W., May 2011, In: Neurosurgical focus. 30, 5, E8.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
Quantitative fluorescence in intracranial tumor: Implications for ALA-induced PpIX as an intraoperative biomarker - Clinical article
Valdés, P. A., Leblond, F., Anthony, K., Harris, B. T., Wilson, B. C., Fan, X., Tosteson, T. D., Hartov, A., Ji, S., Erkmen, K., Simmons, N. E., Paulsen, K. D. & Roberts, D. W., Jul 2011, In: Journal of neurosurgery. 115, 1, p. 11-17 7 p.Research output: Contribution to journal › Article › peer-review
Open Access269 Scopus citations -
2010
Cause-specific mortality among neurosurgeons: Clinical article
Lollis, S. S., Valdes, P. A., Li, Z., Ball, P. A. & Roberts, D. W., Sep 2010, In: Journal of neurosurgery. 113, 3, p. 474-478 5 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Deferoxamine iron chelation increases δ-aminolevulinic acid induced protoporphyrin IX in xenograft glioma model
Valdés, P. A., Samkoe, K., O'Hara, J. A., Roberts, D. W., Paulsen, K. D. & Pogue, B. W., Mar 2010, In: Photochemistry and Photobiology. 86, 2, p. 471-475 5 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Estimation of brain deformation for volumetric image updating in protoporphyrin IX fluorescence-guided resection
Valdés, P. A., Fan, X., Ji, S., Harris, B. T., Paulsen, K. D. & Roberts, D. W., Jan 2010, In: Stereotactic and Functional Neurosurgery. 88, 1, p. 1-10 10 p.Research output: Contribution to journal › Article › peer-review
Open Access50 Scopus citations -
Pre-clinical whole-body fluorescence imaging: Review of instruments, methods and applications
Leblond, F., Davis, S. C., Valdés, P. A. & Pogue, B. W., Jan 21 2010, In: Journal of Photochemistry and Photobiology B: Biology. 98, 1, p. 77-94 18 p.Research output: Contribution to journal › Article › peer-review
Open Access530 Scopus citations -
Review of neurosurgical fluorescence imaging methodologies
Pogue, B. W., Gibbs-Strauss, S. L., Valdés, P. A., Samkoe, K. S., Roberts, D. W. & Paulsen, K. D., May 2010, In: IEEE Journal on Selected Topics in Quantum Electronics. 16, 3, p. 493-505 13 p., 5437303.Research output: Contribution to journal › Article › peer-review
Open Access109 Scopus citations -
2007
Selective incorporation of polyanionic molecules into hamster prions
Geoghegan, J. C., Valdes, P. A., Orem, N. R., Deleault, N. R., Anthony Williamson, R., Harris, B. T. & Supattapone, S., Dec 14 2007, In: Journal of Biological Chemistry. 282, 50, p. 36341-36353 13 p.Research output: Contribution to journal › Article › peer-review
Open Access103 Scopus citations -
1982
5-Aminolevulinic acid-induced protoporphyrin IX fluorescence in meningioma: Qualitative and quantitative measurements in Vivo
Valdes, P. A., Bekelis, K., Harris, B. T., Wilson, B. C., Leblond, F., Kim, A., Simmons, N. E., Erkmen, K., Paulsen, K. D. & Roberts, D. W., 1982, In: Neurosurgery. 10, 1, p. 74-82 9 p.Research output: Contribution to journal › Article › peer-review
Open Access85 Scopus citations