Partha Sarkar, PhD

  • 1444 Citations
  • 25 h-Index
1991 …2021
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  • 7 Similar Profiles
Myotonic Dystrophy Medicine & Life Sciences
RNA Medicine & Life Sciences
Genes Chemical Compounds
Polynucleotide 5'-Hydroxyl-Kinase Medicine & Life Sciences
Repair Chemical Compounds
DNA Glycosylases Chemical Compounds
Phosphoric Monoester Hydrolases Medicine & Life Sciences
Microsatellite Repeats Medicine & Life Sciences

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Projects 2016 2021

Research Output 1991 2019

  • 1444 Citations
  • 25 h-Index
  • 38 Article
  • 1 Book

Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription

Gao, R., Chakraborty, A., Geater, C., Pradhan, S., Gordon, K. L., Snowden, J., Yuan, S., Dickey, A. S., Choudhary, S., Ashizawa, T., Ellerby, L. M., La Spada, A. R., Thompson, L. M., Hazra, T. & Sarkar, P., Apr 17 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Polynucleotide 5'-Hydroxyl-Kinase
Huntington Disease
Transcription
Phosphoric Monoester Hydrolases
DNA Repair
10 Citations (Scopus)

RbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences

Sellier, C., Cerro-Herreros, E., Blatter, M., Freyermuth, F., Gaucherot, A., Ruffenach, F., Sarkar, P., Puymirat, J., Udd, B., Day, J. W., Meola, G., Bassez, G., Fujimura, H., Takahashi, M. P., Schoser, B., Furling, D., Artero, R., Allain, F. H. T., Llamusi, B. & Charlet-Berguerand, N., Dec 1 2018, In : Nature Communications. 9, 1, 2009.

Research output: Contribution to journalArticle

Myotonic Dystrophy
RNA
RNA-Binding Proteins
atrophy
proteins
40 Citations (Scopus)

Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes

Chakraborty, A., Tapryal, N., Venkova, T., Horikoshi, N., Pandita, R. K., Sarker, A. H., Sarkar, P., Pandita, T. K. & Hazra, T., Oct 5 2016, In : Nature Communications. 7, 13049.

Research output: Contribution to journalArticle

Joining
genes
strands
Repair
Genes
20 Citations (Scopus)

Design of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10

Yang, W. Y., Gao, R., Southern, M., Sarkar, P. & Disney, M. D., Jun 1 2016, In : Nature Communications. 7, 11647.

Research output: Contribution to journalArticle

ataxia
activity (biology)
RNA
Molecules
molecules
6 Citations (Scopus)

Glucocorticoids increase skeletal muscle NF-κB inducing kinase (NIK): Links to muscle atrophy

Fry, C., Nayeem, S. Z., Dillon, E., Sarkar, P., Tumurbaatar, B., Urban, R., Wright, T. J., Sheffield-Moore, M., Tilton, R. & Choudhary, S., Nov 1 2016, In : Physiological Reports. 4, 21, e13014.

Research output: Contribution to journalArticle

Muscular Atrophy
Glucocorticoids
Skeletal Muscle
Phosphotransferases
Muscles