Patricia Aguilar, PhD

Associate Director, Center for Tropical Diseases

  • 4950 Citations
  • 27 h-Index
20002021

Research output per year

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Research Output

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2020
2019

Protective immunity by an engineered DNA vaccine for Mayaro virus

Choi, H., Kudchodkar, S. B., Reuschel, E. L., Asija, K., Borole, P., Ho, M., Wojtak, K., Reed, C., Ramos, S., Bopp, N. E., Aguilar, P., Weaver, S., Kim, J. J., Humeau, L., Tebas, P., Weiner, D. B. & Muthumani, K., Feb 1 2019, In : PLoS neglected tropical diseases. 13, 2, p. e0007042

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2018

A recombinant virus vaccine that protects against both Chikungunya and Zika virus infections

Chattopadhyay, A., Aguilar, P., Bopp, N. E., Yarovinsky, T. O., Weaver, S. & Rose, J. K., Jan 1 2018, (Accepted/In press) In : Vaccine.

Research output: Contribution to journalArticle

13 Scopus citations

Genetic characterization of the patois serogroup (Genus Orthobunyavirus; Family Peribunyaviridae) and evidence that estero real virus is a member of the genus orthonairovirus

Aguilar, P., De Souza, W. M., Silvas, J. A., Wood, T., Widen, S., Fumagalli, M. J. & Nunes, M. R. T., Jan 1 2018, In : American Journal of Tropical Medicine and Hygiene. 99, 2, p. 451-457 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Peli1 facilitates virus replication and promotes neuroinflammation during West Nile virus infection

Luo, H., Winkelmann, E. R., Zhu, S., Ru, W., Mays, E., Silvas, J. A., Vollmer, L. L., Gao, J., Peng, B., Bopp, N. E., Cromer, C., Shan, C., Xie, G., Li, G., Tesh, R., Popov, V., Shi, P-Y., Sun, S. C., Wu, P., Klein, R. S. & 4 others, Tang, S-J., Zhang, W., Aguilar, P. & Wang, T., Nov 1 2018, In : The Journal of clinical investigation. 128, 11, p. 4980-4991 12 p.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Extracellular vesicles mediate receptor-independent transmission of novel tick-borne bunyavirus

Silvas, J. A., Popov, V., Paulucci-Holthauzen, A. & Aguilar, P., 2016, In : Journal of Virology. 90, 2, p. 873-886 14 p.

Research output: Contribution to journalArticle

15 Scopus citations

Identification of blood meals from potential arbovirus mosquito vectors in the peruvian amazon basin

Palermo, P. M., Aguilar, P., Sanchez, J. F., Zorrilla, V., Flores-Mendoza, C., Huayanay, A., Guevara, C., Lescano, A. G. & Halsey, E. S., Nov 1 2016, In : American Journal of Tropical Medicine and Hygiene. 95, 5, p. 1026-1030 5 p.

Research output: Contribution to journalArticle

2015

Itaya virus, a novel orthobunyavirus associated with human febrile illness, Peru

Hontz, R. D., Guevara, C., Halsey, E. S., Silvas, J., Santiago, F. W., Widen, S., Wood, T., Casanova, W., Vasilakis, N., Watts, D. M., Kochel, T. J., Ebihara, H. & Aguilar, P., 2015, In : Emerging Infectious Diseases. 21, 5, p. 781-788 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Long-Term Arthralgia after Mayaro Virus Infection Correlates with Sustained Pro-inflammatory Cytokine Response

Santiago, F. W., Halsey, E. S., Siles, C., Vilcarromero, S., Guevara, C., Silvas, J. A., Ramal, C., Ampuero, J. S. & Aguilar, P., Oct 23 2015, In : PLoS Neglected Tropical Diseases. 9, 10, e0004104.

Research output: Contribution to journalArticle

24 Scopus citations
2014

Arboretum and Puerto Almendras viruses: Two novel rhabdoviruses isolated from mosquitoes in Peru

Vasilakis, N., Castro-Llanos, F., Widen, S., Aguilar, P., Guzman, H., Guevara, C., Fernandez, R., Auguste, A. J., Wood, T., Popov, V., Mundal, K., Ghedin, E., Kochel, T. J., Holmes, E. C., Walker, P. J. & Tesh, R. B., 2014, In : Journal of General Virology. 95, PART 4, p. 787-792 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Hijacking of RIG-I signaling proteins into virus-induced cytoplasmic structures correlates with the inhibition of type I interferon responses

Santiago, F. W., Covaleda, L. M., Sanchez-Aparicio, M. T., Silvas, J. A., Diaz-Vizarreta, A. C., Patel, J. R., Popov, V., Yu, X. J., García-Sastre, A. & Aguilar, P., 2014, In : Journal of Virology. 88, 8, p. 4572-4585 14 p.

Research output: Contribution to journalArticle

51 Scopus citations

St. Louis encephalitis virus infection in woman, Peru

Felices, V., Ampuero, J. S., Guevara, C., Caceda, E. R., Gomez, J., Santiago-Maldonado, F. W., Aguilar, P. & Halsey, E. S., 2014, In : Emerging Infectious Diseases. 20, 4, p. 730-732 3 p.

Research output: Contribution to journalArticle

4 Scopus citations
2013

Assessment of plaque assay methods for alphaviruses

Juarez, D., Long, K. C., Aguilar, P., Kochel, T. J. & Halsey, E. S., Jan 2013, In : Journal of Virological Methods. 187, 1, p. 185-189 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Mayaro virus infection, Amazon Basin region, Peru, 2010-2013

Halsey, E. S., Siles, C., Guevara, C., Vilcarromero, S., Jhonston, E. J., Ramal, C., Aguilar, P. & Ampuero, J. S., Nov 2013, In : Emerging Infectious Diseases. 19, 11, p. 1839-1842 4 p.

Research output: Contribution to journalArticle

50 Scopus citations
2012

Erratum: Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors (Nature (2008) 455 (532-536) DOI: 10.1038/nature07231)

Yu, X., Tsibane, T., McGraw, P. A., House, F. S., Keefer, C. J., Hicar, M. D., Tumpey, T. M., Pappas, C., Perrone, L. A., Martinez, O., Stevens, J., Wilson, I. A., Aguilar, P., Altschuler, E. L., Basler, C. F. & Crowe, J. E., Oct 25 2012, In : Nature. 490, 7421, p. 570 1 p.

Research output: Contribution to journalArticle

Ilheus virus infection in human, Bolivia

Venegas, E. A., Aguilar, P., Cruz, C., Guevara, C., Kochel, T. J., Vargas, J. & Halsey, E. S., Mar 2012, In : Emerging Infectious Diseases. 18, 3, p. 516-518 3 p.

Research output: Contribution to journalArticle

8 Scopus citations
2011
61 Scopus citations
35 Scopus citations
2010

Changes in the viral distribution pattern after the appearance of the novel influenza A H1N1 (pHiNi) virus in influenza-like illness patients in Peru

Laguna-Torres, V. A., Gómez, J., Aguilar, P., Ampuero, J. S., Munayco, C., Ocaña, V., Pérez, J., Gamero, M. E., Arrasco, J. C., Paz, I., Chávez, E., Cruz, R., Chavez, J., Mendocilla, S., Gomez, E., Antigoni, J., Gonzalez, S., Tejada, C., Chowell, G. & Kochel, T. J., 2010, In : PLoS One. 5, 7, e11719.

Research output: Contribution to journalArticle

19 Scopus citations

Guaroa virus infection among humans in Bolivia and Peru

Aguilar, P., Morrison, A. C., Rocha, C., Watts, D. M., Beingolea, L., Suarez, V., Vargas, J., Cruz, C., Guevara, C., Montgomery, J. M., Tesh, R. B. & Kochel, T. J., Sep 2010, In : American Journal of Tropical Medicine and Hygiene. 83, 3, p. 714-721 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Venezuelan equine encephalitis and 2 human deaths, Peru

Vilcarromero, S., Aguilar, P., Halsey, E. S., Laguna-Torres, V. A., Razuri, H., Perez, J., Valderrama, Y., Gotuzzo, E., Suárez, L., Céspedes, M. & Kochel, T. J., Mar 2010, In : Emerging Infectious Diseases. 16, 3, p. 553-556 4 p.

Research output: Contribution to journalArticle

10 Scopus citations
2009

Influenza-like illness sentinel surveillance in Peru

Laguna-Torres, V. A., Gómez, J., Ocaña, V., Aguilar, P., Saldarriaga, T., Chavez, E., Perez, J., Zamalloa, H., Forshey, B., Paz, I., Gomez, E., Ore, R., Chauca, G., Ortiz, E., Villaran, M., Vilcarromero, S., Rocha, C., Chincha, O., Jiménez, G., Villanueva, M. & 3 others, Pozo, E., Aspajo, J. & Kochel, T., Jul 1 2009, In : PLoS One. 4, 7, e6118.

Research output: Contribution to journalArticle

68 Scopus citations

Reemergence of Bolivian hemorrhagic fever, 2007-2008

Aguilar, P., Camargo, W., Vargas, J., Guevara, C., Roca, Y., Felices, V., Laguna-Torres, V. A., Tesh, R., Ksiazek, T. & Kochel, T. J., Sep 2009, In : Emerging Infectious Diseases. 15, 9, p. 1526-1528 3 p.

Research output: Contribution to journalArticle

30 Scopus citations

Venezuelan equine encephalitis and upper gastrointestinal bleeding in Child

Vilcarromero, S., Laguna-Torres, V. A., Fernández, C., Gotuzzo, E., Suárez, L., Céspedes, M., Aguilar, P. & Kochel, T. J., Feb 2009, In : Emerging Infectious Diseases. 15, 2, p. 323-325 3 p.

Research output: Contribution to journalArticle

8 Scopus citations
2008
21 Scopus citations

Molecular epidemiology of dengue virus type 3 in Northern South America: 2000-2005

Kochel, T., Aguilar, P., Felices, V., Comach, G., Cruz, C., Alava, A., Vargas, J., Olson, J. & Blair, P., Sep 2008, In : Infection, Genetics and Evolution. 8, 5, p. 682-688 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria

Aiki-Raji, C. O., Aguilar, P., Kwon, Y. K., Goetz, S., Suarez, D. L., Jethra, A. I., Nash, O., Adeyefa, C. A. O., Adu, F. D., Swayne, D. & Basler, C. F., Nov 2008, In : Emerging Infectious Diseases. 14, 11, p. 1753-1755 3 p.

Research output: Contribution to journalArticle

9 Scopus citations
84 Scopus citations

Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus

Pappas, C., Aguilar, P., Basler, C. F., Solórzano, A., Zeng, H., Perrone, L. A., Palese, P., García-Sastre, A., Katz, J. M. & Tumpey, T. M., Feb 26 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 8, p. 3064-3069 6 p.

Research output: Contribution to journalArticle

104 Scopus citations
51 Scopus citations
2007

Capsid protein of eastern equine encephalitis virus inhibits host cell gene expression

Aguilar, P., Weaver, S. & Basler, C. F., Apr 2007, In : Journal of Virology. 81, 8, p. 3866-3876 11 p.

Research output: Contribution to journalArticle

69 Scopus citations

Chimeric Sindbis/eastern equine encephalitis vaccine candidates are highly attenuated and immunogenic in mice

Wang, E., Petrakova, O., Adams, A. P., Aguilar, P., Kang, W., Paessler, S., Volk, S. M., Frolov, I. & Weaver, S., Oct 23 2007, In : Vaccine. 25, 43, p. 7573-7581 9 p.

Research output: Contribution to journalArticle

58 Scopus citations

Endemic eastern equine encephalitis in the Amazon region of Peru

Aguilar, P., Robich, R. M., Turell, M. J., O'Guinn, M. L., Klein, T. A., Huaman, A., Guevara, C., Rios, Z., Tesh, R. B., Watts, D. M., Olson, J. & Weaver, S., Feb 2007, In : American Journal of Tropical Medicine and Hygiene. 76, 2, p. 293-298 6 p.

Research output: Contribution to journalArticle

45 Scopus citations
22 Scopus citations
2006

Genetic relationships among Mayaro and Una viruses suggest distinct patterns of transmission

Powers, A. M., Aguilar, P., Chandler, L. J., Brault, A. C., Meakins, T. A., Watts, D., Russell, K. L., Olson, J., Vasconcelos, P. F. C., Da Rosa, A. T., Weaver, S. & Tesh, R. B., 2006, In : American Journal of Tropical Medicine and Hygiene. 75, 3, p. 461-469 9 p.

Research output: Contribution to journalArticle

49 Scopus citations

Response [2]

Tumpey, T. M., Basler, C. F., Aguilar, P., Zeng, H., Solorzamo, A., Swayne, D. E., Cox, N. J., Katz, J. M., Taubenberger, J. K., Palese, P. & Garcia-Sastre, A., Mar 17 2006, In : Science. 311, 5767, p. 1552 1 p.

Research output: Contribution to journalArticle

Reverse transcription-PCR-enzyme-linked immunosorbent assay for rapid detection and differentiation of alphavirus infections

Wang, E., Paessler, S., Aguilar, P., Carrara, A. S., Ni, K., Greene, I. P. & Weaver, S., Nov 2006, In : Journal of Clinical Microbiology. 44, 11, p. 4000-4008 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Venezuelan equine encephalitis virus transmission and effect on pathogenesis

Smith, D. R., Aguilar, P., Coffey, L. L., Gromowski, G. D., Wang, E. & Weaver, S., 2006, In : Emerging Infectious Diseases. 12, 8, p. 1190-1196 7 p.

Research output: Contribution to journalArticle

30 Scopus citations
2005

A novel, rapid assay for detection and differentiation of serotype-specific antibodies to Venezuelan equine encephalitis complex alphaviruses

Wang, E., Paessler, S., Aguilar, P., Smith, D. R., Coffey, L. L., Kang, W., Pfeffer, M., Olson, J., Blair, P. J., Guevara, C., Estrada-Franco, J. & Weaver, S., Jun 2005, In : American Journal of Tropical Medicine and Hygiene. 72, 6, p. 805-810 6 p.

Research output: Contribution to journalArticle

15 Scopus citations
36 Scopus citations

Transmission of a venezuelan equine encephalitis complex alphavirus by Culex (Melanoconion) gnomatos (Diptera: Culicidae) in Northeastern Peru

Yanoviak, S. P., Aguilar, P., Lounibos, L. P. & Weaver, S., May 2005, In : Journal of Medical Entomology. 42, 3, p. 404-408 5 p.

Research output: Contribution to journalArticle

14 Scopus citations
2004

Endemic Venezuelan Equine Encephalitis in Northern Peru

Aguilar, P., Greene, I. P., Coffey, L. L., Medina, G., Moncayo, A. C., Anishchenko, M., Ludwig, G. V., Turell, M. J., O'Guinn, M. L., Lee, J., Tesh, R. B., Watts, D. M., Russell, K. L., Hice, C., Yanoviak, S., Morrison, A. C., Klein, T. A., Dohm, D. J., Guzman, H., Travassos Da Rosa, A. P. A. & 5 others, Guevara, C., Kochel, T., Olson, J., Cabezas, C. & Weaver, S., May 2004, In : Emerging Infectious Diseases. 10, 5, p. 880-888 9 p.

Research output: Contribution to journalArticle

45 Scopus citations
41 Scopus citations

The hamster as an animal model for eastern equine encephalitis- and its use in studies of virus entrance into the brain

Paessler, S., Aguilar, P., Anishchenko, M., Wang, H. Q., Aronson, J., Campbell, G., Cararra, A. S. & Weaver, S., Apr 1 2004, In : Journal of Infectious Diseases. 189, 11, p. 2072-2076 5 p.

Research output: Contribution to journalArticle

38 Scopus citations
2000

Development of reverse transcription-PCR assays specific for detection of equine encephalitis viruses

Linssen, B., Kinney, R. M., Aguilar, P., Russell, K. L., Watts, D. M., Kaaden, O. R. & Pfeffer, M., 2000, In : Journal of Clinical Microbiology. 38, 4, p. 1527-1535 9 p.

Research output: Contribution to journalArticle

47 Scopus citations