• 14932 Citations
  • 68 h-Index
1993 …2020

Research output per year

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Research Output

Transmembrane domains of NS2B contribute to both viral RNA replication and particle formation in Japanese encephalitis virus

Li, X. D., Deng, C. L., Ye, H. Q., Zhang, H. L., Zhang, Q. Y., Chen, D. D., Zhang, P. T., Shi, P. Y., Yuan, Z. M. & Zhang, B., Jun 1 2016, In : Journal of virology. 90, 12, p. 5735-5749 15 p.

Research output: Contribution to journalArticle

21 Scopus citations

Treatment of human glioblastoma with a live attenuated Zika virus vaccine candidate

Chen, Q., Wu, J., Ye, Q., Ma, F., Zhu, Q., Wu, Y., Shan, C., Xie, X., Li, D., Zhan, X., Li, C., Li, X. F., Qin, X., Zhao, T., Wu, H., Shi, P. Y., Man, J. & Qin, C. F., Sep 1 2018, In : mBio. 9, 5, e01683-18.

Research output: Contribution to journalArticle

19 Scopus citations

Triaryl pyrazoline compound inhibits flavivirus RNA replication

Puig-Basagoiti, F., Tilgner, M., Forshey, B. M., Philpott, S. M., Espina, N. G., Wentworth, D. E., Goebel, S. J., Masters, P. S., Falgout, B., Ren, P., Ferguson, D. M. & Shi, P. Y., Apr 2006, In : Antimicrobial agents and chemotherapy. 50, 4, p. 1320-1329 10 p.

Research output: Contribution to journalArticle

103 Scopus citations

Two distinct sets of NS2A molecules are responsible for dengue virus RNA synthesis and virion assembly

Xie, X., Zou, J., Puttikhunt, C., Yuan, Z. & Shi, P. Y., 2015, In : Journal of virology. 89, 2, p. 1298-1313 16 p.

Research output: Contribution to journalArticle

49 Scopus citations

Type I interferon signals in macrophages and dendritic cells control dengue virus infection: Implications for a new mouse model to test dengue vaccines

Züst, R., Toh, Y. X., Valdés, I., Cerny, D., Heinrich, J., Hermida, L., Marcos, E., Guillén, G., Kalinke, U., Shi, P. Y. & Fink, K., 2014, In : Journal of virology. 88, 13, p. 7276-7285 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

U18666A, an intra-cellular cholesterol transport inhibitor, inhibits dengue virus entry and replication

Poh, M. K., Shui, G., Xie, X., Shi, P. Y., Wenk, M. R. & Gu, F., Jan 1 2012, In : Antiviral research. 93, 1, p. 191-198 8 p.

Research output: Contribution to journalArticle

70 Scopus citations

Understanding zika virus stability and developing a chimeric vaccine through functional analysis

Xie, X., Yang, Y., Muruato, A. E., Zou, J., Shan, C., Nunes, B. T. D., Medeiros, D. B. A., Vasconcelos, P. F. C., Weaver, S. C., Rossi, S. L. & Shi, P. Y., Jan 1 2017, In : mBio. 8, 1, e02134-16.

Research output: Contribution to journalArticle

59 Scopus citations

Unraveling a flavivirus enigma

Shi, P. Y., Jan 1 2014, In : Science. 343, 6173, p. 849-850 2 p.

Research output: Contribution to journalShort survey

6 Scopus citations

Use of the immunoglobulin G avidity assay to differentiate between recent Zika and past dengue virus infections

Furuya, A. K. M., Hunt, D., St. George, K., Dupuis, A. P., Kramer, L. D., Shi, P-Y. & Wong, S., Apr 15 2019, In : Clinical Science. 133, 7, p. 859-867 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Using a virion assembly-defective dengue virus as a vaccine approach

Shan, C., Xie, X., Zou, J., Züst, R., Zhang, B., Ambrose, R., Mackenzie, J., Fink, K. & Shi, P. Y., Nov 1 2018, In : Journal of virology. 92, 21, e01002.

Research output: Contribution to journalArticle

7 Scopus citations

Using next generation sequencing to study the genetic diversity of candidate live attenuated zika vaccines

Collins, N. D., Shan, C., Nunes, B. T. D., Widen, S. G., Shi, P. Y., Barrett, A. D. T. & Sarathy, V. V., Apr 2020, In : Vaccines. 8, 2, 161.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Using recombination-dependent lethal mutations to stabilize reporter flaviviruses for rapid serodiagnosis and drug discovery

Baker, C., Xie, X., Zou, J., Muruato, A., Fink, K. & Shi, P. Y., Jul 2020, In : EBioMedicine. 57, 102838.

Research output: Contribution to journalArticle

Open Access

Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease

Richner, J. M., Jagger, B. W., Shan, C., Fontes, C. R., Dowd, K. A., Cao, B., Himansu, S., Caine, E. A., Nunes, B. T. D., Medeiros, D. B. A., Muruato, A. E., Foreman, B. M., Luo, H., Wang, T., Barrett, A. D., Weaver, S. C., Vasconcelos, P. F. C., Rossi, S. L., Ciaramella, G., Mysorekar, I. U. & 3 others, Pierson, T. C., Shi, P. Y. & Diamond, M. S., Jul 13 2017, In : Cell. 170, 2, p. 273-283.e12

Research output: Contribution to journalArticle

110 Scopus citations

Viral pathogenesis in mice is similar for West Nile virus derived from mosquito and mammalian cells

Lim, P. Y., Louie, K. L., Styer, L. M., Shi, P. Y. & Bernard, K. A., Apr 25 2010, In : Virology. 400, 1, p. 93-103 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

West Nile virus

Kramer, L. D., Li, J. & Shi, P. Y., Feb 1 2007, In : Lancet Neurology. 6, 2, p. 171-181 11 p.

Research output: Contribution to journalReview article

217 Scopus citations

West Nile virus 5′-cap structure is formed by sequential guanine N-7 and ribose 2′-O methylations by nonstructural protein 5

Ray, D., Shah, A., Tilgner, M., Guo, Y., Zhao, Y., Dong, H., Deas, T. S., Zhou, Y., Li, H. & Shi, P. Y., Sep 1 2006, In : Journal of virology. 80, 17, p. 8362-8370 9 p.

Research output: Contribution to journalArticle

246 Scopus citations

West Nile virus drug discovery

Lim, S. P. & Shi, P. Y., Dec 3 2013, In : Viruses. 5, 12, p. 2977-3006 30 p.

Research output: Contribution to journalReview article

26 Scopus citations

West Nile virus envelope protein glycosylation is required for efficient viral transmission by Culex vectors

Moudy, R. M., Zhang, B., Shi, P. Y. & Kramer, L. D., Apr 25 2009, In : Virology. 387, 1, p. 222-228 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

West nile virus experimental evolution in vivo and the trade-off hypothesis

Deardorff, E. R., Fitzpatrick, K. A., Jerzak, G. V. S., Shi, P. Y., Kramer, L. D. & Ebel, G. D., Nov 2011, In : PLoS pathogens. 7, 11, e1002335.

Research output: Contribution to journalArticle

63 Scopus citations

West Nile virus genome cyclization and RNA replication require two pairs of long-distance RNA interactions

Zhang, B., Dong, H., Stein, D. A., Iversen, P. L. & Shi, P. Y., Mar 30 2008, In : Virology. 373, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

71 Scopus citations

West Nile virus infection in birds and mosquitoes, New York State, 2000

Bernard, K. A., Maffei, J. G., Jones, S. A., Kauffman, E. B., Ebel, G. D., Dupuis, A. P., Ngo, K. A., Nicholas, D. C., Young, D. M., Shi, P. Y., Kulasekera, V. L., Eidson, M., White, D. J., Stone, W. B., Backenson, P. B., Gotham, I., Hagiwara, Y., Johnson, G. S., Lukacik, G., Schmit, K. & 2 others, Willsey, A. L. & Kramer, L. D., 2001, In : Emerging infectious diseases. 7, 4, p. 679-685 7 p.

Research output: Contribution to journalArticle

Open Access
193 Scopus citations

West Nile virus infection of Drosophila melanogaster induces a protective RNAi response

Chotkowski, H. L., Ciota, A. T., Jia, Y., Puig-Basagoiti, F., Kramer, L. D., Shi, P. Y. & Glaser, R. L., Jul 20 2008, In : Virology. 377, 1, p. 197-206 10 p.

Research output: Contribution to journalArticle

79 Scopus citations

West Nile virus infection of the placenta

Julander, J. G., Winger, Q. A., Rickords, L. F., Shi, P. Y., Tilgner, M., Binduga-Gajewska, I., Sidwell, R. W. & Morrey, J. D., Mar 30 2006, In : Virology. 347, 1, p. 175-182 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

West Nile virus methyltransferase catalyzes two methylations of the viral RNA cap through a substrate-repositioning mechanism

Dong, H., Ren, S., Zhang, B., Zhou, Y., Puig-Basagoiti, F., Li, H. & Shi, P. Y., May 2008, In : Journal of virology. 82, 9, p. 4295-4307 13 p.

Research output: Contribution to journalArticle

77 Scopus citations

West Nile virus NS1 antagonizes interferon beta production by targeting RIG-I and MDA5

Zhang, H. L., Ye, H. Q., Liu, S. Q., Deng, C. L., Li, X. D., Shi, P. Y. & Zhang, B., Sep 1 2017, In : Journal of virology. 91, 18, e02396-16.

Research output: Contribution to journalArticle

27 Scopus citations

Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network

Aliota, M. T., Bassit, L., Bradrick, S. S., Cox, B., Garcia-Blanco, M. A., Gavegnano, C., Friedrich, T. C., Golos, T. G., Griffin, D. E., Haddow, A. D., Kallas, E. G., Kitron, U., Lecuit, M., Magnani, D. M., Marrs, C., Mercer, N., McSweegan, E., Ng, L. F. P., O'Connor, D. H., Osorio, J. E. & 11 others, Ribeiro, G. S., Ricciardi, M., Rossi, S. L., Saade, G., Schinazi, R. F., Schott-Lerner, G. O., Shan, C., Shi, P. Y., Watkins, D. I., Vasilakis, N. & Weaver, S. C., Aug 2017, In : Antiviral research. 144, p. 223-246 24 p.

Research output: Contribution to journalReview article

60 Scopus citations

Zika structural genes determine the virulence of African and Asian lineages

Nunes, B. T. D., Fontes-Garfias, C. R., Shan, C., Muruato, A. E., Nunes, J. G. C., Burbano, R. M. R., Vasconcelos, P. F. C., Shi, P. Y. & Medeiros, D. B. A., Jan 1 2020, In : Emerging Microbes and Infections. 9, 1, p. 1023-1033 11 p.

Research output: Contribution to journalArticle

Open Access

Zika virus: History, emergence, biology, and prospects for control

Weaver, S., Costa, F., Garcia-Blanco, M., Ko, A. I., Ribeiro, G. S., Saade, G., Shi, P-Y. & Vasilakis, N., Jun 1 2016, In : Antiviral Research. 130, p. 69-80 12 p.

Research output: Contribution to journalArticle

349 Scopus citations

Zika virus: a new threat from mosquitoes

Li, X. F., Han, J. F., Shi, P. Y. & Qin, C. F., Apr 1 2016, In : Science China. Life sciences. 59, 4, p. 440-442 3 p.

Research output: Contribution to journalComment/debate

13 Scopus citations

Zika Virus: Diagnosis, Therapeutics, and Vaccine

Shan, C., Xie, X., Barrett, A., Garcia-Blanco, M., Tesh, R. B., Vasconcelos, P. F. D. C., Vasilakis, N., Weaver, S. & Shi, P-Y., Mar 11 2016, In : ACS Infectious Diseases. 2, 3, p. 170-172 3 p.

Research output: Contribution to journalArticle

53 Scopus citations

Zika virus epidemic in Brazil. I. Fatal disease in adults: Clinical and laboratorial aspects

Azevedo, R. S. S., Araujo, M. T., Martins Filho, A. J., Oliveira, C. S., Nunes, B. T. D., Cruz, A. C. R., Nascimento, A. G. P. A. C., Medeiros, R. C., Caldas, C. A. M., Araujo, F. C., Quaresma, J. A. S., Vasconcelos, B. C. B., Queiroz, M. G. L., da Rosa, E. S. T., Henriques, D. F., Silva, E. V. P., Chiang, J. O., Martins, L. C., Medeiros, D. B. A., Lima, J. A. & 7 others, Nunes, M. R. T., Cardoso, J. F., Silva, S. P., Shi, P. Y., Tesh, R. B., Rodrigues, S. G. & Vasconcelos, P. F. C., Dec 1 2016, In : Journal of Clinical Virology. 85, p. 56-64 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Zika virus has oncolytic activity against glioblastoma stem cells

Zhu, Z., Gorman, M. J., McKenzie, L. D., Chai, J. N., Hubert, C. G., Prager, B. C., Fernandez, E., Richner, J. M., Zhang, R., Shan, C., Tycksen, E., Wang, X., Shi, P. Y., Diamond, M. S., Rich, J. N. & Chheda, M. G., 2017, In : Journal of Experimental Medicine. 214, 10, p. 2843-2857 15 p.

Research output: Contribution to journalArticle

61 Scopus citations

Zika virus infection elicits auto-antibodies to C1q

Koma, T., Veljkovic, V., Anderson, D. E., Wang, L. F., Rossi, S. L., Shan, C., Shi, P. Y., Beasley, D. W., Bukreyeva, N., Smith, J. N., Hallam, S., Huang, C., Von Messling, V. & Paessler, S., Dec 1 2018, In : Scientific reports. 8, 1, 1882.

Research output: Contribution to journalArticle

9 Scopus citations

Zika virus infects human Sertoli cells and modulates the integrity of the in vitro blood-testis barrier model

Siemann, D. N., Strange, D. P., Maharaj, P. N., Shi, P-Y. & Verma, S., Nov 1 2017, In : Journal of Virology. 91, 22, e00623-17.

Research output: Contribution to journalArticle

36 Scopus citations

Zika virus NS2A-mediated virion assembly

Zhang, X., Xie, X., Xia, H., Zou, J., Huang, L., Popov, V. L., Chen, X. & Shi, P. Y., 2019, In : mBio. 10, 5, e02375-19.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease

Akiyama, B. M., Laurence, H. M., Massey, A. R., Costantino, D. A., Xie, X., Yang, Y., Shi, P-Y., Nix, J. C., Beckham, J. D. & Kieft, J. S., Dec 2 2016, In : Science. 354, 6316, p. 1148-1152 5 p.

Research output: Contribution to journalArticle

87 Scopus citations

Zika Virus Replicons for Drug Discovery

Xie, X., Zou, J., Shan, C., Yang, Y., Kum, D. B., Dallmeier, K., Neyts, J. & Shi, P. Y., Oct 1 2016, In : EBioMedicine. 12, p. 156-160 5 p.

Research output: Contribution to journalArticle

40 Scopus citations

Zika Virus Vaccine: Progress and Challenges

Shan, C., Xie, X. & Shi, P-Y., Jan 1 2018, (Accepted/In press) In : Cell Host and Microbe.

Research output: Contribution to journalArticle

31 Scopus citations