Research output per year
Research output per year
- 1 - 50 out of 88 results
Search results
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2021
Diagnostic Efficacy of Recombinase-Polymerase-Amplification Coupled with Lateral Flow Strip Reading in Patients with Cutaneous Leishmaniasis from the Amazonas Rainforest of Perú
Travi, B. L., Delos Santos, M. B., Shelite, T., Santos, R. P., Rosales, L. A., Castellanos-Gonzalez, A., Saldarriaga, O. & Melby, P. C., Dec 2021, In: Vector-Borne and Zoonotic Diseases. 21, 12, p. 941-947 7 p.Research output: Contribution to journal › Article › peer-review
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Diagnostic performance of a recombinant polymerase amplification test—lateral flow (Rpa-lf) for cutaneous leishmaniasis in an endemic setting of Colombia
Cossio, A., Jojoa, J., Castro, M. D. M., Castillo, R. M., Osorio, L., Shelite, T., Saravia, N. G., Melby, P. C. & Travi, B. L., Apr 2021, In: PLoS neglected tropical diseases. 15, 4, e0009291.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Direct RT-PCR amplification of SARS-CoV-2 from clinical samples using a concentrated viral lysis-amplification buffer prepared with IGEPAL-630
Castellanos-Gonzalez, A., Shelite, T. R., Lloyd, N., Sadiqova, A., Ping, R., Williams-Bouyer, N., Melby, P. C. & Travi, B. L., Dec 2021, In: Scientific reports. 11, 1, 14204.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Environmental, metabolic, and inflammatory factors converge in the pathogenesis of moderate acute malnutrition in children: An observational cohort study
Patterson, G. T., Manthi, D., Osuna, F., Muia, A., Olack, B., Mbuchi, M., Saldarriaga, O. A., Ouma, L., Inziani, M., Yu, X., Otieno, P. & Melby, P. C., May 5 2021, In: American Journal of Tropical Medicine and Hygiene. 104, 5, p. 1877-1888 12 p.Research output: Contribution to journal › Article › peer-review
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Isothermal recombinase polymerase amplification-lateral flow detection of SARS-CoV-2, the etiological agent of COVID-19
Shelite, T. R., Uscanga-Palomeque, A. C., Castellanos-Gonzalez, A., Melby, P. C. & Travi, B. L., Oct 2021, In: Journal of Virological Methods. 296, 114227.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Isothermal Recombinase Polymerase Amplification-Lateral Flow Point-of-Care Diagnostic Test for Heartland Virus
Shelite, T., Bopp, N. E., Moncayo, A., Reynolds, E. S., Thangamani, S., Melby, P. C., Bloch, K., Aguilar, P. V. & Travi, B. L., Feb 2021, In: Vector-Borne and Zoonotic Diseases. 21, 2, p. 110-115 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2020
Efficacy of histamine h1 receptor antagonists azelastine and fexofenadine against cutaneous leishmania major infection
Penicheid, A. G., Osorio, E. Y., Melby, P. C. & Travi, B. L., Aug 2020, In: PLoS neglected tropical diseases. 14, 8, p. 1-17 17 p., e0008482.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
In-situ proliferation contributes to the accumulation of myeloid cells in the spleen during progressive experimental visceral leishmaniasis
Osorio, E. Y., Medina-Colorado, A. A., Travi, B. L. & Melby, P. C., Nov 2020, In: PloS one. 15, 11 November, e0242337.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2019
Stunting is preceded by intestinal mucosal damage and microbiome changes and is associated with systemic inflammation in a cohort of Peruvian infants
Zambruni, M., Ochoa, T. J., Somasunderam, A., Cabada, M. M., Morales, M. L., Mitreva, M., Rosa, B. A., Acosta, G. J., Vigo, N. I., Riveros, M., Arango, S., Durand, D., Berends, M. N., Melby, P. & Utay, N., 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 5, p. 1009-1017 9 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
2018
Efficacy of recombinase polymerase amplification to diagnose trypanosoma cruzi infection in dogs with cardiac alterations from an endemic Area of Mexico
Jimenez-Coello, M., Shelite, T., Castellanos-Gonzalez, A., Saldarriaga, O., Rivero, R., Ortega-Pacheco, A., Acevedo-Arcique, C., Amaya-Guardia, K., Garg, N., Melby, P. & Travi, B. L., Aug 1 2018, In: Vector-Borne and Zoonotic Diseases. 18, 8, p. 417-423 7 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Molecular diagnosis of protozoan parasites by Recombinase Polymerase Amplification
Castellanos-Gonzalez, A., White, A. C., Melby, P. & Travi, B., Jun 2018, In: Acta Tropica. 182, p. 4-11 8 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
2017
A review of the global epidemiology of scrub typhus
Xu, G., Walker, D. H., Jupiter, D., Melby, P. C. & Arcari, C. M., Nov 3 2017, In: PLoS neglected tropical diseases. 11, 11, e0006062.Research output: Contribution to journal › Article › peer-review
138 Scopus citations -
A secondary wave of neutrophil infiltration causes necrosis and ulceration in lesions of experimental American cutaneous leishmaniasis
Peniche, A. G., Bonilla, D. L., Palma, G. I., Melby, P. C., Travi, B. L. & Osorio, E. Y., Jun 2017, In: PloS one. 12, 6, e0179084.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Splenic CD4+ T cells in progressive visceral leishmaniasis show a mixed effector-regulatory phenotype and impair macrophage effector function through inhibitory receptor expression
Medina-Colorado, A. A., Osorio, E. Y., Saldarriaga, O. A., Travi, B. L., Kong, F., Spratt, H., Soong, L. & Melby, P. C., Jan 2017, In: PloS one. 12, 1, e0169496.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Transcriptional Profiling in Experimental Visceral Leishmaniasis Reveals a Broad Splenic Inflammatory Environment that Conditions Macrophages toward a Disease-Promoting Phenotype
Kong, F., Saldarriaga, O. A., Spratt, H., Osorio, E. Y., Travi, B. L., Luxon, B. A. & Melby, P. C., Jan 2017, In: PLoS pathogens. 13, 1, e1006165.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
2016
An Innovative Field-Applicable Molecular Test to Diagnose Cutaneous Leishmania Viannia spp. Infections
Saldarriaga, O. A., Castellanos-Gonzalez, A., Porrozzi, R., Baldeviano, G. C., Lescano, A. G., de Los Santos, M. B., Fernandez, O. L., Saravia, N. G., Costa, E., Melby, P. C. & Travi, B. L., Apr 26 2016, In: PLoS neglected tropical diseases. 10, 4, e0004638.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
Cytokine mRNA expression in Peromyscus yucatanicus (Rodentia: Cricetidae) infected by Leishmania (Leishmania) mexicana
Loria-Cervera, E. N., Sosa-Bibiano, E. I., Van Wynsberghe, N. R., Saldarriaga, O. A., Melby, P. C. & Andrade-Narvaez, F. J., Jul 1 2016, In: Cytokine. 83, p. 176-181 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2015
Animal models for the analysis of immune responses to leishmaniasis
Sacks, D. L. & Melby, P. C., 2015, In: Current Protocols in Immunology. 2015, p. 19.2.1-19.2.24Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
A novel molecular test to diagnose canine visceral leishmaniasis at the point of care
Castellanos-Gonzalez, A., Saldarriaga, O. A., Tartaglino, L., Gacek, R., Temple, E., Sparks, H., Melby, P. C. & Travi, B. L., Nov 4 2015, In: American Journal of Tropical Medicine and Hygiene. 93, 5, p. 970-975 6 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Antileishmanial activity of disulfiram and thiuram disulfide analogs in an Ex Vivo model system is selectively enhanced by the addition of divalent metal ions
Peniche-Trujillo, A-G., Renslo, A. R., Melby, P. C. & Travi, B. L., Oct 1 2015, In: Antimicrobial agents and chemotherapy. 59, 10, p. 6463-6470 8 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Permissive and protective roles for neutrophils in leishmaniasis
Carlsen, E. D., Liang, Y., Shelite, T., Walker, D. H., Melby, P. C. & Soong, L., Nov 2015, In: Clinical and Experimental Immunology. 182, 2, p. 109-18 10 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
2014
Deficiency of lymph node-resident dendritic cells (DCs) and dysregulation of DC chemoattractants in a malnourished mouse model of Leishmania donovani infection
Ibrahim, M. K., Barnes, J. L., Osorio, E. Y., Anstead, G. M., Jimenez, F., Osterholzer, J. J., Travi, B. L., Ahuja, S. S., White, A. C. & Melby, P. C., 2014, In: Infection and immunity. 82, 8, p. 3098-3112 15 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Development of an ex vivo lymph node explant model for identification of novel molecules active against leishmania major
Peniche, A. G., Yaneth, O., Renslo, A. R., Frantz, D. E., Melby, P. C. & Travi, B. L., Jan 2014, In: Antimicrobial agents and chemotherapy. 58, 1, p. 78-87 10 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Growth Factor and Th2 Cytokine Signaling Pathways Converge at STAT6 to Promote Arginase Expression in Progressive Experimental Visceral Leishmaniasis
Osorio, E. Y., Travi, B. L., da Cruz, A. M., Saldarriaga, O. A., Medina, A. A. & Melby, P. C., Jun 2014, In: PLoS pathogens. 10, 6, e1004165.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
In situ cytokines (IL-4, IL-10, IL-12, IFN-γ) and chemokines (MCP-1, MIP-1α) gene expression in human Leishmania (Leishmania) mexicana infection
Valencia-Pacheco, G., Loría-Cervera, E. N., Sosa-Bibiano, E. I., Canché-Pool, E. B., Vargas-Gonzalez, A., Melby, P. C. & Andrade-Narvaez, F. J., Sep 2014, In: Cytokine. 69, 1, p. 56-61 6 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Transcriptional profiling of the spleen in progressive visceral leishmaniasis reveals mixed expression of type 1 and type 2 cytokine-responsive genes
Espitia, C. M., Saldarriaga, O. A., Travi, B. L., Osorio, E. Y., Hernandez, A., Band, M., Patel, M. J., Medina, A. A., Cappello, M., Pekosz, A. & Melby, P. C., Nov 26 2014, In: BMC Immunology. 15, 1, 38.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
2013
The Malnutrition-Related Increase in Early Visceralization of Leishmania donovani Is Associated with a Reduced Number of Lymph Node Phagocytes and Altered Conduit System Flow
Ibrahim, M. K., Barnes, J. L., Anstead, G. M., Jimenez, F., Travi, B. L., Peniche, A. G., Osorio, E. Y., Ahuja, S. S. & Melby, P. C., Aug 2013, In: PLoS neglected tropical diseases. 7, 8, e2329.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
2012
Identification of hamster inducible nitric oxide synthase (iNOS) promoter sequences that influence basal and inducible iNOS expression
Saldarriaga, O. A., Travi, B. L., Choudhury, G. G. & Melby, P. C., Jul 2012, In: Journal of Leukocyte Biology. 92, 1, p. 205-218 14 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Progressive visceral leishmaniasis is driven by dominant parasite-induced STAT6 activation and STAT6-dependent host arginase 1 expression
Osorio, E. Y., Zhao, W., Espitia, C., Saldarriaga, O., Hawel, L., Byus, C. V., Travi, B. L. & Melby, P. C., Jan 2012, In: PLoS pathogens. 8, 1, e1002417.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
2011
Identification of small molecule lead compounds for visceral leishmaniasis using a novel ex vivo splenic explant model system
Osorio, Y., Travi, B. L., Renslo, A. R., Peniche, A. G. & Melby, P. C., Feb 2011, In: PLoS neglected tropical diseases. 5, 2, e962.Research output: Contribution to journal › Article › peer-review
Open Access54 Scopus citations -
2010
CCR2 plays a critical role in dendritic cell maturation: Possible role of CCL2 and NF-κB
Jimenez, F., Quinones, M. P., Martinez, H. G., Estrada, C. A., Clark, K., Garavito, E., Ibarra, J., Melby, P. C. & Ahuja, S. S., May 15 2010, In: Journal of Immunology. 184, 10, p. 5571-5581 11 p.Research output: Contribution to journal › Article › peer-review
70 Scopus citations -
Duplex real-time reverse transcriptase PCR to determine cytokine mRNA expression in a hamster model of New World cutaneous leishmaniasis
Espitia, C. M., Zhao, W., Saldarriaga, O., Osorio, Y., Harrison, L. M., Cappello, M., Travi, B. L. & Melby, P. C., Jun 22 2010, In: BMC Immunology. 11, 31.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
2009
Clinical, parasitologic, and immunologic evolution in dogs experimentally infected with sand fly-derived Leishmania chagasi promastigotes
Travi, B. L., Osorio, E. Y., Saldarriaga, O. A., Cadena, H., Tabares, C. J., Peniche, A., Lee, S. & Melby, P. C., Dec 2009, In: American Journal of Tropical Medicine and Hygiene. 81, 6, p. 994-1003 10 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Malnutrition promotes prostaglandin over leukotriene production and dysregulates eicosanoid-cytokine crosstalk in activated resident macrophages
Anstead, G. M., Zhang, Q. & Melby, P. C., Jul 2009, In: Prostaglandins Leukotrienes and Essential Fatty Acids. 81, 1, p. 41-51 11 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Prophylaxis with cationic liposome-DNA complexes protects hamsters from phleboviral disease: Importance of liposomal delivery and CpG motifs
Gowen, B. B., Fairman, J., Dow, S., Troyer, R., Wong, M. H., Jung, K. H., Melby, P. C. & Morrey, J. D., Jan 2009, In: Antiviral research. 81, 1, p. 37-46 10 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
WISP1, a pro-mitogenic, pro-survival factor, mediates tumor necrosis factor-α (TNF-α)-stimulated cardiac fibroblast proliferation but inhibits TNF-α-induced cardiomyocyte death
Venkatachalam, K., Venkatesan, B., Valente, A. J., Melby, P. C., Nandish, S., Reusch, J. E. B., Clark, R. A. & Chandrasekar, B., May 22 2009, In: Journal of Biological Chemistry. 284, 21, p. 14414-14427 14 p.Research output: Contribution to journal › Article › peer-review
88 Scopus citations -
2008
Immunoprophylaxis of Punta Toro virus (Phlebovirus, Bunyaviridae) infection in hamsters with recombinant Eimeria profilin-like antigen
Gowen, B. B., Judge, J. W., Wong, M. H., Jung, K. H., Aylsworth, C. F., Melby, P. C., Rosenberg, B. & Morrey, J. D., Aug 2008, In: International Immunopharmacology. 8, 8, p. 1089-1094 6 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Pregnancy enhances the innate immune response in experimental cutaneous leishmaniasis through hormone-modulated nitric oxide production
Osorio, Y., Bonilla, D. L., Peniche, A. G., Melby, P. C. & Travi, B. L., Jun 1 2008, In: Journal of Leukocyte Biology. 83, 6, p. 1413-1422 10 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
2006
Biological activity of hamster interferon-gamma is modulated by the carboxyl-terminal tail
Zhao, W., Valencia, A. Z. & Melby, P. C., Jun 2006, In: Cytokine. 34, 5-6, p. 243-251 9 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
CC chemokine receptor (CCR)-2 prevents arthritis development following infection by Mycobacterium avium
Quinones, M. P., Jimenez, F., Martinez, H., Estrada, C. A., Willmon, O., Dudley, M., Kuziel, W. A., Melby, P. C., Reddick, R. L., Ahuja, S. K. & Ahuja, S. S., May 2006, In: Journal of Molecular Medicine. 84, 6, p. 503-512 10 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Immunogenicity of a multicomponent DNA vaccine against visceral leishmaniasis in dogs
Saldarriaga, O. A., Travi, B. L., Park, W., Perez, L. E. & Melby, P. C., Mar 10 2006, In: Vaccine. 24, 11, p. 1928-1940 13 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
Leishmania amazonensis infections in Oryzomys acritus and Oryzomys nitidus from Bolivia
Kerr, S. F., Emmons, L. H., Melby, P. C., Liu, C., Perez, L. E., Villegas, M. & Miranda, R., Dec 2006, In: American Journal of Tropical Medicine and Hygiene. 75, 6, p. 1069-1073 5 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Quantification of canine cytokines using real time reverse transcriptase polymerase chain reaction.
Saldarriaga, O. A., Travi, B. L. & Melby, P. C., Oct 2006, In: Biomédica : revista del Instituto Nacional de Salud. 26 Suppl 1, p. 254-263 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Reduced nitric oxide synthase 2 (NOS2) promoter activity in the Syrian hamster renders the animal functionally deficient in NOS2 activity and unable to control an intracellular pathogen
Perez, L. E., Chandrasekar, B., Saldarriaga, O. A., Zhao, W., Arteaga, L. T., Travi, B. L. & Melby, P. C., May 1 2006, In: Journal of Immunology. 176, 9, p. 5519-5528 10 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Selective enhancement of the type 1 cytokine response by expression of a canine interleukin (IL)-12 fused heterodimeric DNA
Saldarriaga, O. A., Perez, L. E., Travi, B. L. & Melby, P. C., Apr 15 2006, In: Veterinary Immunology and Immunopathology. 110, 3-4, p. 377-388 12 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2003
CC Chemokine Receptor 2 Expression in Donor Cells Serves an Essential Role in Graft-versus-Host-Disease
Rao, A. R., Quinones, M. P., Garavito, E., Kalkonde, Y., Jimenez, F., Gibbons, C., Perez, J., Melby, P., Kuziel, W., Reddick, R. L., Ahuja, S. K. & Ahuja, S. S., Oct 1 2003, In: Journal of Immunology. 171, 9, p. 4875-4885 11 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Chemokine-cytokine cross-talk: The ELR+ CXC chemokine LIX (CXCl5) amplifies a proinflammatory cytokine response via a phosphatidylinositol 3-kinase-NF-κB pathway
Chandrasekar, B., Melby, P. C., Sarau, H. M., Raveendran, M., Perla, R. P., Marelli-Berg, F. M., Dulin, N. O. & Singh, I. S., Feb 14 2003, In: Journal of Biological Chemistry. 278, 7, p. 4675-4686 12 p.Research output: Contribution to journal › Article › peer-review
84 Scopus citations -
Fractalkine (CX3CL1) stimulated by nuclear factor κB (NF-κB)-dependent inflammatory signals induces aortic smooth muscle cell proliferation through an autocrine pathway
Chandrasekar, B., Mummidi, S., Perla, R. P., Bysani, S., Dulin, N. O., Liu, F. & Melby, P. C., Jul 15 2003, In: Biochemical Journal. 373, 2, p. 547-558 12 p.Research output: Contribution to journal › Article › peer-review
135 Scopus citations -
Multinutrient undernutrition dysregulates the resident macrophage proinflammatory cytokine network, nuclear factor-κB activation, and nitric oxide production
Anstead, G. M., Chandrasekar, B., Zhang, Q. & Melby, P. C., Dec 2003, In: Journal of Leukocyte Biology. 74, 6, p. 982-991 10 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
Short report: A disseminated infection of Leishmania mexicana in an eastern woodrat, Neotoma floridana, collected in Texas
McHugh, C. P., Thies, M. L., Melby, P. C., Yantis, L. D., Raymond, R. W., Villegas, M. D. & Kerr, S. F., Nov 2003, In: American Journal of Tropical Medicine and Hygiene. 69, 5, p. 470-472 3 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations