Phillip Lee, MD

Division Director, Endocrinology

  • 4851 Citations
  • 40 h-Index
1977 …2019

Research output per year

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Research Output

1997

Modulation of growth factors by growth hormone in children with chronic renal failure

Powell, D. R., Liu, F., Baker, B. K., Hintz, R. L., Lee, P. D. K., Durham, S. K., Brewer, E. D., Frane, J. W., Watkins, S. L. & Hogg, R. J., Jan 1 1997, In : Kidney International. 51, 6, p. 1970-1979 10 p.

Research output: Contribution to journalArticle

Open Access
67 Scopus citations

Synthesis of IGFBP-3 fragments in a baculovirus system and characterization of monoclonal anti-IGFBP-3 antibodies

Vorwerk, P., Oh, Y., Lee, P. D. K., Khare, A. & Rosenfeld, R. G., Jul 22 1997, In : Journal of Clinical Endocrinology and Metabolism. 82, 7, p. 2368-2370 3 p.

Research output: Contribution to journalArticle

24 Scopus citations
1996

A homologous radioimmunoassay for rat insulin-like growth factor-I (IGF-I): Implications for studies of human IGF-I physiology

Lee, P. D. K., Baker, B. K., Liu, F., Kwan, E. Y. W. & Hintz, R. L., Dec 1 1996, In : Journal of Clinical Endocrinology and Metabolism. 81, 5, p. 2002-2005 4 p.

Research output: Contribution to journalArticle

21 Scopus citations

A randomized, placebo-controlled trial of combined insulin-like growth factor I and low dose growth hormone therapy for wasting associated with human immunodeficiency virus infection

Lee, P. D. K., Pivarnik, J. M., Bukar, J. G., Muurahainen, N., Berry, P. S., Skolnik, P. R., Nerad, J. L., Kudsk, K. A., Jackson, L., Ellis, K. J. & Gesundheit, N., Oct 8 1996, In : Journal of Clinical Endocrinology and Metabolism. 81, 8, p. 2968-2975 8 p.

Research output: Contribution to journalArticle

69 Scopus citations

Changes in body composition of human immunodeficiency virus-infected males receiving insulin-like growth factor I and growth hormone

Ellis, K. J., Lee, P. D. K., Pivarnik, J. M., Bukar, J. G. & Gesundheit, N., Oct 8 1996, In : Journal of Clinical Endocrinology and Metabolism. 81, 8, p. 3033-3038 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

Characterization of insulin-like growth factors and their binding proteins in peritoneal dialysate

Kale, A. S., Liu, F., Hintz, R. L., Baker, B. K., Brewer, E. D., Lee, P. D. K., Durham, S. K. & Powell, D. R., Aug 22 1996, In : Pediatric Nephrology. 10, 4, p. 467-473 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Erratum: A randomized, placebo-controlled trial of combined insulin- like growth factor I and low dose growth hormone therapy for wasting associated with human immunodeficiency virus infection (Journal of Clinical Endocrinology and Metabolism (1996) 81 (2968-2975))

Lee, P. D. K., Pivarnik, J. M., Bukar, J. G., Muurahainen, N., Berry, P. S., Skolnik, P. R., Nerad, J. L., Kudsk, K. A., Jackson, L., Ellis, K. J. & Gesundheit, N., Jan 1 1996, In : Journal of Clinical Endocrinology and Metabolism. 81, 10, 1 p.

Research output: Contribution to journalComment/debate

Insulin-like growth factor-binding protein-1 expression in cultured human bone cells: Regulation by insulin and glucocorticoid

Conover, C. A., Lee, P. D. K., Riggs, B. L. & Powell, D. R., Jan 1 1996, In : Endocrinology. 137, 8, p. 3295-3301 7 p.

Research output: Contribution to journalArticle

Open Access
54 Scopus citations

Insulin-like growth factor binding proteins as growth inhibitors in children with chronic renal failure

Powell, D. R., Liu, F., Baker, B. K., Lee, P. D. K. & Hintz, R. L., Jun 1996, In : Pediatric Nephrology. 10, 3, p. 343-347 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Noncompetitive ELISA for human serum insulin-like growth factor-I

Khosravi, M. J., Diamandi, A., Mistry, J. & Lee, P. D. K., Aug 21 1996, In : Clinical chemistry. 42, 8, p. 1147-1154 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Serum and Follicular Fluid Levels of Insulin-Like Growth Factor I (IGF-I), IGF-II, and IGF-Binding Protein-1 and -3 during the Normal Menstrual Cycle

Van Dessel, H. J. H. M. T., Chandrasekher, Y., Yap, O. W. S., Lee, P. D. K., Hintz, R. L., Faessen, G. H. J., Braat, D. D. M., Fauser, B. C. J. M. & Giudice, L. C., Dec 1 1996, In : Journal of Clinical Endocrinology and Metabolism. 81, 3, p. 1224-1231 8 p.

Research output: Contribution to journalArticle

120 Scopus citations
1995

Altered Regulation of Insulin-Like Growth Factor Binding Protein-I in Patients With Polycystic Ovary Syndrome

Carmina, E., Stanczyk, F. Z., Morris, R. S., Lee, P. D. K., Savjani, G. & Lobo, R. A., Nov 1995, In : Journal of the Society for Gynecologic Investigation. 2, 6, p. 743-747 5 p.

Research output: Contribution to journalArticle

21 Scopus citations
1994

Immunoblot studies of the IGF-related acid-labile subunit

Liu, F., Hintz, R. L., Khare, A., Diaugustine, R. P., Powell, D. R. & Lee, P. D. K., Dec 1994, In : Journal of Clinical Endocrinology and Metabolism. 79, 6, p. 1883-1886 4 p.

Research output: Contribution to journalArticle

23 Scopus citations
1993

Body composition studies in Prader-Willi syndrome: effects of growth hormone therapy.

Lee, P. D., Hwu, K., Henson, H., Brown, B. T., Bricker, J. T., LeBlanc, A. D., Fiorotto, M. L., Greenberg, F. & Klish, W. J., 1993, In : Basic life sciences. 60, p. 201-205 5 p.

Research output: Contribution to journalArticle

33 Scopus citations

Characterization of insulin-like growth factor binding protein-3 in chronic renal failure serum

Powell, D. R., Liu, F., Baker, B., Lee, P. D. K., Belsha, C. W., Brewer, E. D. & Hintz, R. L., Feb 1993, In : Pediatric Research. 33, 2, p. 136-143 8 p.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations

Cortisol increases plasma insulin-like growth factor binding protein-1 in humans

Conover, C. A., Divertie, G. D. & Lee, P. D. K., Jan 1 1993, In : Acta Endocrinologica. 128, 2, p. 140-143 4 p.

Research output: Contribution to journalArticle

85 Scopus citations

Dexamethasone stimulates expression of insulin-like growth factor binding protein-1 in HEP G2 human hepatoma cells

Powell, D., Lee, P. D. K., DePaolis, L. A., Morris, S. L. & Suwanichkul, A., Jan 1 1993, In : Growth Regulation. 3, 1, p. 11-13 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

Identification of a promoter element which participates in cAMP- stimulated expression of human insulin-like growth factor-binding protein-1

Suwanichkul, A., DePaolis, L. A., Lee, P. D. K. & Powell, D. R., Jan 1 1993, In : Journal of Biological Chemistry. 268, 13, p. 9730-9736 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Insulin-like growth factor (IGF) suppression of IGFBP-1 production: evidence for mediation by the type I IGF receptor

Lee, P. D. K., Suwanichkul, A., DePaolis, L. A., Snuggs, M. B., Morris, S. L. & Powell, D. R., Oct 20 1993, In : Regulatory Peptides. 48, 1-2, p. 199-206 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Insulin-like growth factor-binding protein-1 response to insulin during suppression of endogenous insulin secretion

Lee, P. D. K., Jensen, M. D., Divertie, G. D., Heiling, V. J., Katz, H. H. & Conover, C. A., Apr 1993, In : Metabolism. 42, 4, p. 409-414 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Literature abstract

Wilson, D. M., Lee, P. D. K., Morris, A. H., Reiter, E. O., Gertner, J. M., Marcus, R., Quarmby, V. E. & Rosenfeld, R. G., Feb 1 1993, In : Pediatric Nephrology. 7, 1, 1 p.

Research output: Contribution to journalArticle

Multihormonal regulation of IGFBP-1 promoter activity

Powell, D. R., Lee, P. D. K. & Suwanichkul, A., Dec 1 1993, In : Advances in experimental medicine and biology. 343, p. 205-214 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Regulation and Function of Insulin-Like Growth Factor-Binding Protein-1

Lee, P. D. K., Conover, C. A. & Powell, D. R., Oct 1993, In : Proceedings of the Society for Experimental Biology and Medicine. 204, 1, p. 4-29 26 p.

Research output: Contribution to journalArticle

350 Scopus citations
1992

An outpatient-focused program for childhood diabetes: design, implementation, and effectiveness.

Lee, P. D., Jul 1992, In : Texas medicine. 88, 7, p. 64-68 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Comparisons of home blood glucose testing and glycated protein measurements

Lee, P. D. K., Sherman, L. D., O'Day, M. R., Rognerud, C. L. & Ou, C. N., Apr 1992, In : Diabetes Research and Clinical Practice. 16, 1, p. 53-62 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Endocrine status and growth hormone treatment in Prader-Willi syndrome

Hwu, K., Klish, W. J., Henson, H., Brown, B., Bricker, J., LeBlanc, A., Fiorotto, M., Greenberg, F., Ledbetter, D. & Lee, P., Dec 1 1992, In : Dysmorphology and Clinical Genetics. 6, 2, 1 p.

Research output: Contribution to journalArticle

Insulin regulation of insulin-like growth factor binding protein-1 in obese and nonobese humans

Conover, C. A., Lee, P. D. K., Kanaley, J. A., Clarkson, J. T. & Jensen, M. D., Jun 1992, In : Journal of Clinical Endocrinology and Metabolism. 74, 6, p. 1355-1360 6 p.

Research output: Contribution to journalArticle

201 Scopus citations

Role of protein kinase-C in regulation of insulin-like growth factor-binding protein-1 production by HepG2 cells

Lee, P. D. K., Abdel-Maguid, L. S. & Snuggs, M. B., Aug 1992, In : Journal of Clinical Endocrinology and Metabolism. 75, 2, p. 459-464 6 p.

Research output: Contribution to journalArticle

15 Scopus citations
1991

Erratum: Lack of growth hormone effect on insulin-associated suppression of insulinlike growth factor binding protein 1 in humans (Diabetes (1990) 39 (1251-1256))

Conover, C. A., Butler, P. C., Wang, M., Rizza, R. A. & Lee, P. D. K., Jan 1 1991, In : Diabetes. 40, 11, 1 p.

Research output: Contribution to journalComment/debate

Growth Hormone Therapy in Hypophosphatemic Rickets

Wilson, D. M., Lee, P. D. K., Morris, A. H., Reiter, E. O., Gertner, J. M., Marcus, R., Quarmby, V. E. & Rosenfeld, R. G., Oct 1991, In : American Journal of Diseases of Children. 145, 10, p. 1165-1170 6 p.

Research output: Contribution to journalArticle

48 Scopus citations

Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1

Powell, D. R., Suwanichkul, A., Cubbage, M. L., DePaolis, L. A., Snuggs, M. B. & Lee, P. D. K., Nov 22 1991, In : Journal of Biological Chemistry. 266, 28, p. 18868-18876 9 p.

Research output: Contribution to journalArticle

181 Scopus citations
1990

Efficacy of insulin-like growth factor I levels in predicting the response to provocative growth hormone testing

Lee, P. D. K., Wilson, D. M., Rountree, L., Hintz, R. L. & Rosenfeld, R. G., Jan 1990, In : Pediatric Research. 27, 1, p. 45-51 7 p.

Research output: Contribution to journalArticle

Open Access
49 Scopus citations

Insulin-like growth factor-I and insulin-like growth factor-binding protein in the toad, Bufo woodhousei

Pancak-Roessler, M. K. & Lee, P. D. K., May 1990, In : General and Comparative Endocrinology. 78, 2, p. 263-272 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Insulin regulation of insulin-like growth factor-binding protein production in cultured hepG2 cells

Conover, C. A. & Lee, P. D. K., Apr 1990, In : Journal of Clinical Endocrinology and Metabolism. 70, 4, p. 1062-1067 6 p.

Research output: Contribution to journalArticle

79 Scopus citations

Lack of growth hormone effect on insulin-associated suppression of insulinlike growth factor binding protein 1 in humans

Conover, C. A., Butler, P. C., Wang, M., Rizza, R. A. & Lee, P. D. K., Oct 1990, In : Diabetes. 39, 10, p. 1251-1256 6 p.

Research output: Contribution to journalArticle

47 Scopus citations

The Use of Anabolic Steroids

Lee, P. D. K., Sep 1990, In : American Journal of Diseases of Children. 144, 9, p. 954-955 2 p.

Research output: Contribution to journalLetter

1 Scopus citations
1989

IGF binding proteins in growth-retarded children with chronic renal failure

Lee, P. D. K., Hintz, R. L., Sperry, J. B., Baxter, R. C. & Powell, D. R., Oct 1989, In : Pediatric Research. 26, 4, p. 308-315 8 p.

Research output: Contribution to journalArticle

Open Access
89 Scopus citations

Insulin-like growth factor (IGF)-I and IGF-binding activity in normal and fast-growing chickens

Lee, P. D. K., Peacock, A., Roessler, M. K., Hester, J. & Reeves, J. T., 1989, In : Life Sciences. 45, 25, p. 2465-2470 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Insulin-like growth factoristimulates elastin synthesis by bovine pulmonary arterial smooth muscle cells

Badesch, D. B., Lee, P. D. K., Parks, W. C. & Stenmark, K. R., Apr 14 1989, In : Biochemical and Biophysical Research Communications. 160, 1, p. 382-387 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Serum levels of 25kDa insulin-like growth factor binding protein in children with insulin-dependent diabetes mellitus

Wang, M., Wilson, D. M. & Lee, P. D. K., Dec 1 1989, Insuline-like Growth Factor binding proteins: proceedings of a workshop on Insuline-like Growth Factor binding proteins. ICS881. Drop, S. L. S., Hintz, R. L., Drop, S. L. S. & Hintz, R. L. (eds.). Elsevier Science Publishers B.V., p. 39-45 7 p. (Insuline-like Growth Factor binding proteins: proceedings of a workshop on Insuline-like Growth Factor binding proteins. ICS881).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

The insulin-like growth factor binding protein BP-25 is expressed by human breast cancer cells

Yee, D., Favoni, R. E., Lupu, R., Cullen, K. J., Lebovic, G. S., Huff, K. K., Lee, P. D. K., Lee, Y. L., Powell, D. R., Dickson, R. B., Rosen, N. & Lippman, M. E., Jan 16 1989, In : Biochemical and Biophysical Research Communications. 158, 1, p. 38-44 7 p.

Research output: Contribution to journalArticle

54 Scopus citations
1988

High molecular weight forms of insulin-like growth factor II and its binding protein identified by protein immunoblotting

Lee, P. D. K., Powell, D. R., Li, C. H., Bohn, H., Liu, F. & Hintz, R. L., May 16 1988, In : Biochemical and Biophysical Research Communications. 152, 3, p. 1131-1137 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
Open Access
191 Scopus citations

Presence of insulinlike growth factor receptors and lack of insulin receptors on fetal bovine smooth muscle cells

Lee, P. D. K., Hintz, R. L., Rosenfeld, R. G. & Benitz, W. E., Sep 1 1988, In : In Vitro Cellular & Developmental Biology. 24, 9, p. 921-926 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Virilizing Adrenal Adenoma in a 15-Year-Old Girl

Lee, P. D. K. & Green, O. C., Mar 11 1988, In : JAMA: The Journal of the American Medical Association. 259, 10, p. 1497-1498 2 p.

Research output: Contribution to journalLetter

1987
40 Scopus citations

Clinical utility of insulin-like growth factor assays

Lee, P. D. K. & Rosenfeld, R. G., Dec 1 1987, In : Pediatrician. 14, 3, p. 154-161 8 p.

Research output: Contribution to journalReview article

15 Scopus citations

Heterogeneity of insulin-like growth factor-I affinity for the insulin-like growth factor-II receptor: Comparison of natural, synthetic and recombinant DNA-derived insulin-like growth factor-I

Rosenfeld, R. G., Conover, C. A., Hodges, D., Lee, P. D. K., Misra, P., Hintz, R. L. & Li, C. H., Feb 27 1987, In : Biochemical and Biophysical Research Communications. 143, 1, p. 199-205 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

Linear growth response to exogenous growth hormone in Prader-Willi syndrome

Lee, P. D. K., Wilson, D. M., Rountree, L., Hintz, R. L. & Rosenfeld, R. G., Jan 1 1987, In : American Journal of Medical Genetics. 28, 4, p. 865-871 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Method for purification of an insulin-like growth factor-binding protein produced by human HEP G2 hepatoma cells

Powell, D. R., Lee, P. D. K., Shively, J. E., Eckenhausen, M. & Hintz, R. L., 1987, In : Journal of Chromatography B: Biomedical Sciences and Applications. 420, C, p. 163-170 8 p.

Research output: Contribution to journalArticle

37 Scopus citations