Ping Wu, MD, PhD

  • 2280 Citations
  • 26 h-Index
1990 …2021

Research output per year

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Research Output

  • 2280 Citations
  • 26 h-Index
  • 58 Article
  • 3 Review article
  • 2 Editorial
  • 1 Comment/debate
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Article
2019

Chronic poly-drug administration damages adult mouse brain neural stem cells

McGrath, E. L., Schlagal, C. R., Cortez, I., Dunn, T. J., Gao, J., Fox, R. G., Stutz, S. J., Kuo, Y. F., Hommel, J., Dineley, K., Cunningham, K., Kaphalia, B. & Wu, P., Nov 15 2019, In : Brain Research. 1723, 146425.

Research output: Contribution to journalArticle

Ferroptosis inhibitor SRS 16-86 attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury

Zhang, Y., Sun, C., Zhao, C., Hao, J., Zhang, Y., Fan, B., Li, B., Duan, H., Liu, C., Kong, X., Wu, P., Yao, X. & Feng, S., Mar 1 2019, In : Brain Research. 1706, p. 48-57 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

Mitra, J., Guerrero, E. N., Hegde, P. M., Liachko, N. F., Wang, H., Vasquez, V., Gao, J., Pandey, A., Paul Taylor, J., Kraemer, B. C., Wu, P., Boldogh, I., Garruto, R. M., Mitra, S., Rao, K. S. & Hegde, M. L., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 10, p. 4696-4705 10 p.

Research output: Contribution to journalArticle

24 Scopus citations
2018

Clinical Cell Therapy Guidelines for Neurorestoration (IANR/CANR 2017)

Huang, H., Young, W., Chen, L., Feng, S., Zoubi, Z. M. A., Sharma, H. S., Saberi, H., Moviglia, G. A., He, X., Muresanu, D. F., Sharma, A., Otom, A., Andrews, R. J., Al-Zoubi, A., Bryukhovetskiy, A. S., Chernykh, E. R., Domańska-Janik, K., Jafar, E., Johnson, W. E., Li, Y. & 47 others, Li, D., Luan, Z., Mao, G., Shetty, A. K., Siniscalco, D., Skaper, S., Sun, T., Wang, Y., Wiklund, L., Xue, Q., You, S. W., Zheng, Z., Dimitrijevic, M. R., Masri, W. S. E., Sanberg, P. R., Xu, Q., Luan, G., Chopp, M., Cho, K. S., Zhou, X. F., Wu, P., Liu, K., Mobasheri, H., Ohtori, S., Tanaka, H., Han, F., Feng, Y., Zhang, S., Lu, Y., Zhang, Z., Rao, Y., Tang, Z., Xi, H., Wu, L., Shen, S., Xue, M., Xiang, G., Guo, X., Yang, X., Hao, Y., Hu, Y., Li, J., Ao, Q., Wang, B., Zhang, Z., Lu, M. & Li, T., Feb 1 2018, In : Cell Transplantation. 27, 2, p. 310-324 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines

Dawes, B. E., Gao, J., Atkins, C., Nelson, J. T., Johnson, K., Wu, P. & Freiberg, A., Nov 15 2018, In : Journal of Neuroinflammation. 15, 1, 1 p.

Research output: Contribution to journalArticle

5 Scopus citations

Oligodendrocyte differentiation from human neural stem cells: A novel role for c-Src

Wang, L., Schlagal, C. R., Gao, J., Hao, Y., Dunn, T. J., McGrath, E. L., Labastida, J. A., Yu, Y., Feng, S. Q., Liu, S. Y. & Wu, P., Nov 1 2018, In : Neurochemistry International. 120, p. 21-32 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Peli1 facilitates virus replication and promotes neuroinflammation during West Nile virus infection

Luo, H., Winkelmann, E. R., Zhu, S., Ru, W., Mays, E., Silvas, J. A., Vollmer, L. L., Gao, J., Peng, B., Bopp, N. E., Cromer, C., Shan, C., Xie, G., Li, G., Tesh, R., Popov, V., Shi, P-Y., Sun, S. C., Wu, P., Klein, R. S. & 4 others, Tang, S-J., Zhang, W., Aguilar, P. & Wang, T., Nov 1 2018, In : The Journal of clinical investigation. 128, 11, p. 4980-4991 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Proteomic changes in traumatic brain injury: experimental approaches

Sowers, J. L., Wu, P., Zhang, K., Dewitt, D. & Prough, D., Dec 1 2018, In : Current Opinion in Neurology. 31, 6, p. 709-717 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Zika virus infection of cultured human fetal brain neural stem cells for immunocytochemical analysis

McGrath, E. L., Gao, J. & Wu, P., Feb 5 2018, In : Journal of Visualized Experiments. 2018, 132, e56917.

Research output: Contribution to journalArticle

2017

Aged dominant negative p38α MAPK mice are resistant to age-dependent decline in adult-neurogenesis and context discrimination fear conditioning

Cortez, I. D., Bulavin, D. V., Wu, P., McGrath, E. L., Cunningham, K. A., Wakamiya, M., Papaconstantinou, J. & Dineley, K. T., Mar 30 2017, In : Behavioural Brain Research. 322, p. 212-222 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection

Barrows, N. J., Kroon Campos, R., Powell, S. T., Prasanth, K. R., Schott-Lerner, G., Soto-Acosta, R., Galarza-Munoz, G., McGrath, E. L., Urrabaz-Garza, R., Gao, J., Wu, P., Menon, R., Saade, G., Fernandez-Salas, I., Rossi, S., Vasilakis, N., Routh, A., Bradrick, S. & Garcia-Blanco, M., May 15 2016, (Accepted/In press) In : Cell Host and Microbe.

Research output: Contribution to journalArticle

190 Scopus citations

Development of a stretch-induced neurotrauma model for medium-throughput screening in vitro: Identification of rifampicin as a neuroprotectant

López-García, I., Gero, D., Szczesny, B., Szoleczky, P., Olah, G., Modis, K., Zhang, K., Gao, J., Wu, P., Sowers, L., Dewitt, D., Prough, D. & Szabo, C., 2016, (Accepted/In press) In : British Journal of Pharmacology.

Research output: Contribution to journalArticle

7 Scopus citations

Differential Responses of Human Fetal Brain Neural Stem Cells to Zika Virus Infection

McGrath, E. L., Rossi, S. L., Gao, J., Widen, S. G., Grant, A. C., Dunn, T. J., Azar, S. R., Roundy, C. M., Xiong, Y., Prusak, D. J., Loucas, B. D., Wood, T., Yu, Y., Fernández-Salas, I., Weaver, S. C., Vasilakis, N. & Wu, P., Jul 27 2016, (Accepted/In press) In : Stem Cell Reports.

Research output: Contribution to journalArticle

51 Scopus citations

Human neural stem cell transplantation-mediated alteration of microglial/macrophage phenotypes after traumatic brain injury

Gao, J., Grill, R. J., Dunn, T. J., Bedi, S., Labastida, J. A., Hetz, R. A., Xue, H., Thonhoff, J. R., Dewitt, D., Prough, D., Cox, C. S. & Wu, P., 2016, In : Cell Transplantation. 25, 10, p. 1863-1877 15 p.

Research output: Contribution to journalArticle

19 Scopus citations

Molecular Turbocharging Stem Cells to Improve Treatment of Experimental Spinal Cord Injury

Wu, P. & Prough, D., Mar 1 2016, In : Critical Care Medicine. 44, 3, p. 649-650 2 p.

Research output: Contribution to journalArticle

Spatial and Sex-Dependent Responses of Adult Endogenous Neural Stem Cells to Alcohol Consumption

McGrath, E. L., Gao, J., Kuo, Y. F., Dunn, T. J., Ray, M. J., Dineley, K. T., Cunningham, K. A., Kaphalia, B. S. & Wu, P., Aug 7 2016, (Accepted/In press) In : Stem Cell Reports.

Research output: Contribution to journalArticle

4 Scopus citations
2015

Efficient reverse genetics reveals genetic determinants of budding and fusogenic differences between Nipah and Hendra viruses and enables real-time monitoring of viral spread in small animal models of henipavirus infection

Yun, T., Park, A., Hill, T. E., Pernet, O., Beaty, S. M., Juelich, T. L., Smith, J. K., Zhang, L., Wang, Y. E., Vigant, F., Gao, J., Wu, P., Lee, B. & Freiberg, A. N., Jan 1 2015, In : Journal of virology. 89, 2, p. 1242-1253 12 p.

Research output: Contribution to journalArticle

34 Scopus citations

Quantification of Histone Modifications by Parallel-Reaction Monitoring: A Method Validation

Sowers, J. L., Mirfattah, B., Xu, P., Tang, H., Park, I. Y., Walker, C., Wu, P., Laezza, F., Sowers, L. C. & Zhang, K., Oct 6 2015, In : Analytical Chemistry. 87, 19, p. 10006-10014 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
2014

Ethanol suppresses PGC-1α expression by interfering with the cAMP-CREB pathway in neuronal cells

Liu, Z., Liu, Y., Gao, R., Li, H., Dunn, T., Wu, P., Smith, R. G., Sarkar, P. S. & Fang, X., Aug 6 2014, In : PloS one. 9, 8, e104247.

Research output: Contribution to journalArticle

14 Scopus citations

STAT3 modulation to enhance motor neuron differentiation in human neural stem cells

Natarajan, R., Singal, V., Benes, R., Gao, J., Chan, H., Chen, H., Yu, Y., Zhou, J. & Wu, P., Jun 19 2014, In : PloS one. 9, 6, e100405.

Research output: Contribution to journalArticle

11 Scopus citations
2013

A Hamster-Derived West Nile Virus Isolate Induces Persistent Renal Infection in Mice

Saxena, V., Xie, G., Li, B., Farris, T., Welte, T., Gong, B., Boor, P., Wu, P., Tang, S. J., Tesh, R. & Wang, T., Jun 2013, In : PLoS neglected tropical diseases. 7, 6, e2275.

Research output: Contribution to journalArticle

22 Scopus citations

Detection of structural and metabolic changes in traumatically injured hippocampus by quantitative differential proteomics

Wu, P., Zhao, Y., Haidacher, S. J., Wang, E., Parsley, M. O., Gao, J., Sadygov, R. G., Starkey, J. M., Luxon, B. A., Spratt, H., Dewitt, D. S., Prough, D. S. & Denner, L., May 1 2013, In : Journal of neurotrauma. 30, 9, p. 775-788 14 p.

Research output: Contribution to journalArticle

16 Scopus citations

Elevated expression of serotonin 5-HT2A receptors in the rat ventral tegmental area enhances vulnerability to the behavioral effects of cocaine

Herin, D. V., Bubar, M. J., Seitz, P. K., Thomas, M. L., Hillman, G. R., Tarasenko, Y. I., Wu, P. & Cunningham, K. A., May 17 2013, In : Frontiers in Psychiatry. 4, FEB, Article 2.

Research output: Contribution to journalArticle

10 Scopus citations
29 Scopus citations
2012

Molecular mechanisms underlying effects of neural stem cells against traumatic axonal injury

Wang, E., Gao, J., Yang, Q., Parsley, M. O., Dunn, T. J., Zhang, L., Dewitt, D. S., Denner, L., Prough, D. S. & Wu, P., Jan 20 2012, In : Journal of neurotrauma. 29, 2, p. 295-312 18 p.

Research output: Contribution to journalArticle

22 Scopus citations
7 Scopus citations
2011

Critical role of PI3k/Akt/GSK3β in motoneuron specification from human neural stem cells in response to FGF2 and EGF

Ojeda, L., Gao, J., Hooten, K. G., Wang, E., Thonhoff, J. R., Dunn, T. J., Gao, T. & Wu, P., Aug 24 2011, In : PloS one. 6, 8, e23414.

Research output: Contribution to journalArticle

41 Scopus citations
2009

Generation of spinal motor neurons from human fetal brain-derived neural stem cells: Role of basic fibroblast growth factor

Jordan, P. M., Ojeda, L. D., Thonhoff, J. R., Gao, J., Boehning, D., Yu, Y. & Wu, P., Feb 1 2009, In : Journal of Neuroscience Research. 87, 2, p. 318-332 15 p.

Research output: Contribution to journalArticle

42 Scopus citations

Toll-like receptor 7-induced immune response to cutaneous West Nile virus infection

Welte, T., Reagan, K., Fang, H., Machain-Williams, C., Zheng, X., Mendell, N., Chang, G. J. J., Wu, P., Blair, C. D. & Wang, T., Nov 9 2009, In : Journal of General Virology. 90, 11, p. 2660-2668 9 p.

Research output: Contribution to journalArticle

68 Scopus citations
2008

Astrocytes enhance long-term survival of cholinergic neurons differentiated from human fetal neural stem cells

Jordan, P. M., Cain, L. D. & Wu, P., Jan 1 2008, In : Journal of Neuroscience Research. 86, 1, p. 35-47 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Compatibility of human fetal neural stem cells with hydrogel biomaterials in vitro

Thonhoff, J. R., Lou, D. I., Jordan, P. M., Zhao, X. & Wu, P., Jan 2 2008, In : Brain Research. 1187, 1, p. 42-51 10 p.

Research output: Contribution to journalArticle

102 Scopus citations
2007

Functional motoneurons develop from human neural stem cell transplants in adult rats

Gao, J., Coggeshall, R. E., Chung, J. M., Wang, J. & Wu, P., Apr 1 2007, In : NeuroReport. 18, 6, p. 565-569 5 p.

Research output: Contribution to journalArticle

33 Scopus citations

Human fetal neural stem cells grafted into contusion-injured rat spinal cords improve behavior

Tarasenko, Y. I., Gao, J., Nie, L., Johnson, K. M., Grady, J. J., Hulsebosch, C. E., McAdoo, D. J. & Wu, P., Jan 1 2007, In : Journal of Neuroscience Research. 85, 1, p. 47-57 11 p.

Research output: Contribution to journalArticle

81 Scopus citations

Identification of early disease progression in an ALS rat model

Thonhoff, J. R., Jordan, P. M., Karam, J. R., Bassett, B. L. & Wu, P., Mar 30 2007, In : Neuroscience Letters. 415, 3, p. 264-268 5 p.

Research output: Contribution to journalArticle

7 Scopus citations
2006

Gene expression profiling and analysis of signaling pathways involved in priming and differentiation of human neural stem cells

Cai, Y., Wu, P., Ozen, M., Yu, Y., Wang, J., Ittmann, M. & Liu, M., Feb 16 2006, In : Neuroscience. 138, 1, p. 133-148 16 p.

Research output: Contribution to journalArticle

23 Scopus citations

Transplantation of primed human fetal neural stem cells improves cognitive function in rats after traumatic brain injury

Gao, J., Prough, D. S., McAdoo, D. J., Grady, J. J., Parsley, M. O., Ma, L., Tarensenko, Y. I. & Wu, P., Oct 2006, In : Experimental Neurology. 201, 2, p. 281-292 12 p.

Research output: Contribution to journalArticle

132 Scopus citations
2005

Human neural stem cell-derived cholinergic neurons innervate muscle in motoneuron deficient adult rats

Gao, J., Coggeshall, R. E., Tarasenko, Y. I. & Wu, P., Jan 1 2005, In : Neuroscience. 131, 2, p. 257-262 6 p.

Research output: Contribution to journalArticle

99 Scopus citations
2004

Effect of growth factors on proliferation and phenotypic differentiation of human fetal neural stem cells

Tarasenko, Y. I., Yu, Y., Jordan, P. M., Bottenstein, J. & Wu, P., Dec 1 2004, In : Journal of Neuroscience Research. 78, 5, p. 625-636 12 p.

Research output: Contribution to journalArticle

78 Scopus citations
2003
74 Scopus citations

Efficiencies of transgene expression in nociceptive neurons through different routes of delivery of adeno-associated viral vectors

Xu, Y., Gu, Y., Wu, P., Li, G. W. & Huang, L. Y. M., Jun 10 2003, In : Human Gene Therapy. 14, 9, p. 897-906 10 p.

Research output: Contribution to journalArticle

66 Scopus citations
2002

Region-specific generation of cholinergic neurons from fetal human neural stem cells grafted in adult rat

Wu, P., Tarasenko, Y. I., Gu, Y., Huang, L. Y. M., Coggeshall, R. E. & Yu, Y., Dec 1 2002, In : Nature Neuroscience. 5, 12, p. 1271-1278 8 p.

Research output: Contribution to journalArticle

186 Scopus citations

Transduction of human neural progenitor cells using recombinant adeno-associated viral vectors

Wu, P., Ye, Y. & Svendsen, C. N., Jan 1 2002, In : Gene Therapy. 9, 4, p. 245-255 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

Transduction of human neural progenitor cells using recombinant adeno-associated viral vectors

Wu, P., Ye, Y. & Svendsen, C. N., 2002, In : Gene Therapy. 9, 4, p. 245-255 11 p.

Research output: Contribution to journalArticle

2000

Differential expression of growth hormone messenger ribonucleic acid by somatotropes and gonadotropes in male and cycling female rats

Childs, G. V., Unabia, G. & Wu, P., Jan 1 2000, In : Endocrinology. 141, 4, p. 1560-1570 11 p.

Research output: Contribution to journalArticle

Open Access
55 Scopus citations
1998

Adeno-associated virus-mediated delivery of antiangiogenic factors as an antitumor strategy

Nguyen, J. T., Wu, P., Clouse, M. E., Hlatky, L. & Terwilliger, E. F., Dec 15 1998, In : Cancer Research. 58, 24, p. 5673-5677 5 p.

Research output: Contribution to journalArticle

118 Scopus citations

Adeno-associated virus vector-mediated transgene integration into neurons and other nondividing cell targets

Wu, P., Phillips, M. I., Bui, J. & Terwilliger, E. F., Jul 1 1998, In : Journal of virology. 72, 7, p. 5919-5926 8 p.

Research output: Contribution to journalArticle

117 Scopus citations
1997

Prolonged reduction of high blood pressure with an in vivo, nonpathogenic, adeno-associated viral vector delivery of AT1-R mRNA antisense

Phillips, M. I., Mohuczy-Dominiak, D., Coffey, M., Galli, S. M., Kimura, B., Wu, P. & Zelles, T., Jan 1 1997, In : Hypertension. 29, 1 II, p. 374-380 7 p.

Research output: Contribution to journalArticle

69 Scopus citations
1996

An AAV promoter-driven neuropeptide Y gene delivery system using Sendai virosomes for neurons and rat brain

Wu, P., De Fiebre, C. M., Millard, W. J., King, M. A., Wang, S., Bryant, S. O., Gao, Y. P., Martin, E. J. & Meyer, E. M., Mar 1 1996, In : Gene Therapy. 3, 3, p. 246-253 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons

Wu, P., Price, P., Du, B., Hatch, W. C. & Terwilliger, E. F., Jan 1 1996, In : NeuroReport. 7, 5, p. 1045-1049 5 p.

Research output: Contribution to journalArticle

42 Scopus citations

Efficient transduction of human neurons with an adeno-associated virus vector

Du, B., Wu, P., Boldt-Houle, D. M. & Terwilliger, E. F., Mar 1 1996, In : Gene Therapy. 3, 3, p. 254-261 8 p.

Research output: Contribution to journalArticle

66 Scopus citations