Pomila Singh, PhD, MS

Program Director, Cell Biology

  • 4150 Citations
  • 37 h-Index
1978 …2019

Research output per year

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Research Output

1995
Open Access
113 Scopus citations
1994
58 Scopus citations

Expression of IGF-II and IGF-binding proteins by colon cancer cells in relation to growth response to IGFs

Singh, P., Dai, B., Yallampalli, C. & Xu, Z., Jan 1 1994, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 267, 4 30-4, p. G608-G617

Research output: Contribution to journalArticle

54 Scopus citations

Gastrin gene expression in human colon cancer cells measured by a simple competitive PCR method

Xu, Z., Dai, B., Dhruva, B. & Singh, P., 1994, In : Life Sciences. 54, 10, p. 671-678 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Incomplete processing of progastrin expressed by human colon cancer cells: Role of noncarboxyamidated gastrins

Singh, P., Xu, Z., Dai, B., Rajaraman, S., Rubin, N. & Dhruva, B., Jan 1 1994, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 266, 3 29-3, p. G459-G468

Research output: Contribution to journalArticle

70 Scopus citations

Phosphorylation of pp62 and pp54 src-like proteins in a rat intestinal cell line in response to gastrin

Singh, P., Narayan, S. & Adiga, R. B., Jan 1 1994, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 267, 2 30-2, p. G235-G244

Research output: Contribution to journalArticle

29 Scopus citations
1993

Insulinlike growth factors and binding proteins in colon cancer

Singh, P. & Rubin, N., Oct 1993, In : Gastroenterology. 105, 4, p. 1218-1237 20 p.

Research output: Contribution to journalReview article

125 Scopus citations

In vivo mitogenic effects of estradiol on colon cancers: Role of gastrin and gastrin receptors

Singh, P., Reubi, J. C., Rajakumar, G., Guo, Y. S., Prioux, H. & Chicone, L., Jul 1993, In : Journal of Steroid Biochemistry and Molecular Biology. 46, 1, p. 49-60 12 p.

Research output: Contribution to journalArticle

9 Scopus citations
1992

A novel bombesin receptor antagonist (2258U89), potently inhibits bombesin evoked release of gastrointestinal hormones from rats and dogs, in vitro and in vivo

Singh, P., Guo, Y. S., Kull, F. C. & Leban, J. J., Jul 2 1992, In : Regulatory Peptides. 40, 1, p. 75-86 12 p.

Research output: Contribution to journalArticle

17 Scopus citations
13 Scopus citations

Characterization of gastrin binding to colonic mucosal membranes of guinea pigs

Narayan, S., Chicione, L. & Singh, P., Jun 1 1992, In : Molecular and Cellular Biochemistry. 112, 2, p. 163-171 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Characterization of insulinlike growth factor I receptors in human colon cancer

Guo, Y. S., Narayan, S., Yallampalli, C. & Singh, P., Apr 1992, In : Gastroenterology. 102, 4 PART 1, p. 1101-1108 8 p.

Research output: Contribution to journalArticle

156 Scopus citations

Early stages of gallstone formation in guinea pig are associated with decreased biliary sensitivity to cholecystokinin

Poston, G. J., Singh, P., Draviam, E., Yao, C. Z., Gomez, G. & Thompson, J. C., Aug 1 1992, In : Digestive Diseases and Sciences. 37, 8, p. 1236-1244 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Estradiol is trophic for colon cancer in mice: Effect on ornithine decarboxylase and c-myc messenger RNA

Narayan, S., Rajakumar, G., Prouix, H. & Singh, P., Dec 1992, In : Gastroenterology. 103, 6, p. 1823-1832 10 p.

Research output: Contribution to journalArticle

35 Scopus citations
1991

Characterization of secretin release in response to food and intraduodenal administration of fat and hydrochloric acid

Draviam, E. J., Gomez, G., Hashimoto, T., Miyashita, T., Hill, F. L. C., Uchida, T., Singh, P., Greeley, G. H. & Thompson, J. C., Apr 1 1991, In : Digestive Diseases and Sciences. 36, 4, p. 513-519 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Establishment and characterization of a human carcinoid in nude mice and effect of various agents on tumor growth

Evers, B. M., Townsend, C. M., Upp, J. R., Allen, E., Hurlbut, S. C., Kim, S. W., Rajaraman, S., Singh, P., Reubi, J. C. & Thompson, J. C., Aug 1991, In : Gastroenterology. 101, 2, p. 303-311 9 p.

Research output: Contribution to journalArticle

157 Scopus citations

High-affinity binding sites for bombesin on mouse colonic mucosal membranes

Narayan, S., Draviam, E., Rajaraman, S. & Singh, P., Jul 1 1991, In : Molecular and Cellular Biochemistry. 106, 1, p. 31-39 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

IGF-I and IGF-I receptor in mouse colon cancer cells

Singh, P., Narayan, S., Guo, Y. S. & Chandrasekhar, Y., Oct 1 1991, In : In Vitro Cellular & Developmental Biology - Animal. 27, 10, p. 755-758 4 p.

Research output: Contribution to journalLetter

15 Scopus citations

Receptors for insulin-like growth factor II in the rat uterus: Characterization and variation throughout the estrus cycle

Chandrasekhar, Y., Narayan, S., Singh, P. & Nagamani, M., Jan 1 1991, In : Acta Endocrinologica. 124, 4, p. 434-441 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Specific binding of cholecystokinin, estradiol and somatostatin to human pancreatic cancer xenografts

Singh, P., Townsend, C. M., Poston, G. J. & Reubi, J. C., Nov 1991, In : Journal of Steroid Biochemistry and Molecular Biology. 39, 5 PART 1, p. 759-767 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
1990

Binding of insulin-like growth factor-I to rat uterus; variations during sensitization and decidualization

Chandrasekhar, Y., Narayan, S., Singh, P. & Nagamani, M., Jan 1 1990, In : Acta Endocrinologica. 123, 2, p. 243-250 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Differential Effects of Ca2+ on Proliferation of Stomach, Colonic, and Pancreatic Cancer Cell Lines In Vitro

Guo, Y. S., Draviam, E., Townsend, C. & Singh, P., Jan 1 1990, In : Nutrition and Cancer. 14, 2

Research output: Contribution to journalArticle

17 Scopus citations

Effect of somatostatin and tamoxifen on the growth of human pancreatic cancers in nude mice

Poston, G. J., Townsend, C. M., Rajaraman, S., Thompson, J. C. & Singh, P., Mar 1990, In : Pancreas. 5, 2, p. 151-157 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Growth-promoting effects of gastrin on mouse colon cancer cells in vitro: Absence of autocrine effects

Guo, Y. S., Baijal, M., Jin, G. F., Thompson, J. C., Townsend, C. M. & Singh, P., Sep 1 1990, In : In Vitro Cellular & Developmental Biology. 26, 9, p. 871-877 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Gut hormones in colon cancer: Past and prospective studies

Singh, P., Townsend, C. M., Thompson, J. C., Narayan, S. & Guo, Y. S., Mar 9 1990, In : Cancer Journal. 3, 1, p. 28-33 6 p.

Research output: Contribution to journalReview article

15 Scopus citations

Molecular characterization of bombesin receptors on rat pancreatic acinar AR42J cells

Singh, P., Draviam, E., Guo, Y. S. & Kurosky, A., Jan 1 1990, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 258, 5 21-5, p. G803-G809

Research output: Contribution to journalArticle

27 Scopus citations

Role of gastrin in bombesin-stimulated somatostatin release

Guo, Y. S., Thompson, J. C. & Singh, P., Nov 1990, In : Gastroenterology. 99, 5, p. 1297-1302 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Specific Binding and Growth Effects of Bombesin-related Peptides on Mouse Colon Cancer Cells in Vitro

Narayan, S., Guo, Y. S., Townsend, C. M. & Singh, P., Nov 15 1990, In : Cancer Research. 50, 21, p. 6772-6778 7 p.

Research output: Contribution to journalArticle

65 Scopus citations
1989

Clinical Significance of Gastrin Recentors in Human Colon Cancers

Udd, J. R., Singh, P., Townsend, C. M. & Thompson, J. C., Jan 15 1989, In : Cancer Research. 49, 2, p. 488-492 5 p.

Research output: Contribution to journalArticle

157 Scopus citations

Contractile response of canine gallbladder and sphincter of Oddi to substance P and related peptides in vitro

Guo, Y. S., Singh, P., Gomez, G., Rajaraman, S. & Thompson, J. C., Jun 1 1989, In : Digestive Diseases and Sciences. 34, 6, p. 812-817 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Down-regulation of pancreatic growth and gallbladder contractility by bile salts

Gomez, G., Townsend, C. M., Maani, R., Singh, P., Greeley, G. G. & Thompson, J. C., Jan 1989, In : The American Journal of Surgery. 157, 1, p. 20-26 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Effect of estradiol on pancreatic amylase and cholecystokinin binding in ovariectomized guinea pigs

Guo, Y. S. & Singh, P., Sep 1989, In : Journal of Steroid Biochemistry. 33, 3, p. 459-464 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Effect of γ-aminobutyric acid on bombesin-evoked release of somatostatin and gastrin from isolated rat stomach

Guo, Y. S., Thompson, J. C. & Singh, P., Feb 1989, In : Regulatory Peptides. 24, 2, p. 179-186 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effects of gastrointestinal peptides on gastrointestinal cancer growth

Townsend, C. M., Singh, P. & Thompson, J. C., Dec 1 1989, In : Gastroenterology Clinics of North America. 18, 4, p. 777-791 15 p.

Research output: Contribution to journalReview article

26 Scopus citations

Peptide YY inhibits the insulinotropic action of gastric inhibitory polypeptide

Guo, Y. S., Singh, P., Draviam, E., Greeley, G. H. & Thompson, J. C., Jan 1 1989, In : Gastroenterology. 96, 3, p. 690-694 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Role of protein kinase C and phosphorylation in bombesin-evoked gastrin release from isolated perfused rat stomach

Guo, Y. S., Thompson, J. C. & Singh, P., Aug 1989, In : Regulatory Peptides. 26, 1, p. 19-25 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Species-specific effects of neurotensin on gallbladder contraction in vitro

Guo, Y. S., Singh, P., Upp, J. R. & Thompson, J. C., Jan 1 1989, In : Digestive Diseases and Sciences. 34, 1, p. 21-26 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

The presence of a 33-40 KDa gastrin binding protein on human and mouse colon cancer

Chicone, L., Narayan, S., Townsend, C. M. & Singh, P., Oct 16 1989, In : Biochemical and Biophysical Research Communications. 164, 1, p. 512-519 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
1988

A comparison of the insulinotropic and the insulin-inhibitory actions of gut peptides on newborn and adult rat islet cells

Ishizuka, J., Singh, P., Greeley, G. H., Townsend, C. M., Cooper, C. W., Tatemoto, K. & Thompson, J. C., Feb 1988, In : Pancreas. 3, 1, p. 77-82 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Age-related changes in gallbladder contractility and gallbladder cholecystokinin receptor population in the guinea pig

Poston, G. J., Singh, P., Maclellan, D. G., Yao, C. Z., Uchida, T., Townsend, C. M. & Thompson, J. C., 1988, In : Mechanisms of Ageing and Development. 46, 1-3, p. 225-236 12 p.

Research output: Contribution to journalArticle

23 Scopus citations
13 Scopus citations

Bombesin inhibits growth of human pancreatic adenocarcinoma in nude mice

Alexander, R. W., Upp, J. R., Poston, G. J., Townsend, C. M., Singh, P. & Thompson, J. C., May 1988, In : Pancreas. 3, 3, p. 297-302 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

Cholecystokinin receptor and gallbladder contractility

Upp, J. R., Singh, P. & Thompson, J. C., Jan 1988, In : Gastroenterology. 94, 1, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Circadian rhythms in gastrin receptors in rat fundic stomach

Rubin, N. H., Singh, P., Alinder, G., Greeley, G. H., Rayford, P. L., Rietveld, WOP. J. & Thompson, J. C., Aug 1 1988, In : Digestive Diseases and Sciences. 33, 8, p. 931-937 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Development and age-related changes in pancreatic cholecystokinin receptors and duodenal cholecystokinin in guinea pigs

Poston, G. J., Singh, P., Draviam, E. J., Upp, J. R. & Thompson, J. C., 1988, In : Mechanisms of Ageing and Development. 46, 1-3, p. 59-66 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Effect of aging on gastric acid secretion, serum gastrin, and antral gastrin content in rats

Khalil, T., Singh, P., Fujimura, M., Townsend, C. M., Greeley, G. H. & Thompson, J. C., Dec 1 1988, In : Digestive Diseases and Sciences. 33, 12, p. 1544-1548 5 p.

Research output: Contribution to journalArticle

36 Scopus citations

Effect of cyclic nucleotides on bombesin-evoked gastrin release from isolated perfused rat stomach

Guo, Y. S., Bhalla, V. K., Thompson, J. C. & Singh, P., Sep 1988, In : Regulatory Peptides. 22, 4, p. 361-369 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Effect of peptide YY on insulin release stimulated by 2-deoxyglucose and neuropeptides in dogs

Guo, Y. S., Singh, P., Debouno, J. F. & Thompson, J. C., Apr 1988, In : Pancreas. 3, 2, p. 128-134 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Growth factors and intestinal neoplasms

Townsend, C. M., Beauchamp, R. D., Singh, P. & Thompson, J. C., Mar 1988, In : The American Journal of Surgery. 155, 3, p. 526-536 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

Inhibition of Gastric Acid Secretion by Peptide YY Is Independent of Gastric Somatostatin Release in the Rat

Greeley, G. H., Guo, Y. S., Gomez, G., Lluis, F., Singh, P. & Thompson, J. C., Dec 1988, In : Proceedings of the Society for Experimental Biology and Medicine. 189, 3, p. 325-328 4 p.

Research output: Contribution to journalArticle

24 Scopus citations