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Rakez Kayed, PhD

  • 18589 Citations
  • 50 h-Index
19972022
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  • 12 Similar Profiles
Amyloid Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Poisons Medicine & Life Sciences
Tauopathies Medicine & Life Sciences
Oligomers Chemical Compounds
Brain Medicine & Life Sciences
Neurodegenerative Diseases Medicine & Life Sciences
Neurofibrillary Tangles Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2022

Multi target combinatory therapy for Alzheimer's Disease

Kayed, R.

Darrell K. Royal Research Fund for Alzhe

8/22/18 → 8/31/20

Project: Other project

Tau in the Eye and Brain

Kayed, R.

National Inst on Aging

9/1/17 → 6/30/22

Project: Other project

Myocardial Tauopathy: a New Pathogenesis and Treatment for Heart Disease

Kayed, R.

Medical University of South Carolin

7/1/17 → 6/30/20

Project: Other project

Intersection of Alpha-Synuclein and Tau Contributions To Neurotoxicity

Kayed, R.

National Inst of Neurological Disorders

9/15/16 → 6/30/21

Project: Other project

Formation and Propagation of Tau Oligomeric Strains in Alzheimer's disease

Kayed, R.

National Inst on Aging

7/15/16 → 3/31/21

Project: Other project

Research Output 1997 2019

Amyloid oligomer interactions and polymorphisms: disease-relevant distinct assembly of α-synuclein and tau

Sengupta, U. & Kayed, R., Jan 1 2019, In : Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 44, 1, p. 222-223 2 p.

Research output: Contribution to journal › Comment/debate

alpha-Synuclein
Amyloid
1 Citation (Scopus)

NLRP3 inflammasome activation drives tau pathology

Ising, C., Venegas, C., Zhang, S., Scheiblich, H., Schmidt, S. V., Vieira-Saecker, A., Schwartz, S., Albasset, S., McManus, R. M., Tejera, D., Griep, A., Santarelli, F., Brosseron, F., Opitz, S., Stunden, J., Merten, M., Kayed, R., Golenbock, D. T., Blum, D., Latz, E. & 2 others, Buée, L. & Heneka, M. T., Nov 28 2019, In : Nature. 575, 7784, p. 669-673 5 p.

Research output: Contribution to journal › Article

Inflammasomes
Amyloid
Pathology
Neurofibrillary Tangles
Microglia
1 Citation (Scopus)

Tau Interacts with the C-Terminal Region of α-Synuclein, Promoting Formation of Toxic Aggregates with Distinct Molecular Conformations

Dasari, A. K. R., Kayed, R., Wi, S. & Lim, K. H., Jun 25 2019, In : Biochemistry. 58, 25, p. 2814-2821 8 p.

Research output: Contribution to journal › Article

Synucleins
Molecular Conformation
Poisons
Conformations
Agglomeration

Tau oligomers mediate aggregation of RNA-binding proteins Musashi1 and Musashi2 inducing Lamin alteration

Montalbano, M., McAllen, S., Sengupta, U., Puangmalai, N., Bhatt, N., Ellsworth, A. & Kayed, R., Dec 1 2019, In : Aging Cell. 18, 6, e13035.

Research output: Contribution to journal › Article

Open Access
Tauopathies
Lamins
RNA-Binding Proteins
Poisons
Alzheimer Disease
2 Citations (Scopus)

AAV2-mediated GRP78 transfer alleviates retinal neuronal injury by downregulating ER stress and Tau oligomer formation

Ha, Y., Liu, W., Liu, H., Zhu, S., Xia, F., Gerson, J. E., Azhar, N. A., Tilton, R., Motamedi, M., Kayed, R. & Zhang, W., Sep 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 11, p. 4670-4682 13 p.

Research output: Contribution to journal › Article

Endoplasmic Reticulum Stress
Nerve Crush
Retinal Ganglion Cells
Optic Nerve
Down-Regulation