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Rakez Kayed, PhD

Program Director, Neurobiology of Disease

  • 17683 Citations
  • 50 h-Index
19972022
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  • 12 Similar Profiles
Amyloid Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Poisons Medicine & Life Sciences
Oligomers Chemical Compounds
Tauopathies Medicine & Life Sciences
Brain Medicine & Life Sciences
Neurodegenerative Diseases Medicine & Life Sciences
Neurofibrillary Tangles Medicine & Life Sciences

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Projects 2013 2022

Multi target combinatory therapy for Alzheimer's Disease

Kayed, R.

8/22/18 → 8/31/19

Project: Other project

Tau in the Eye and Brain

Kayed, R.

9/1/17 → 6/30/22

Project: Other project

Myocardial Tauopathy: a New Pathogenesis and Treatment for Heart Disease

Kayed, R.

7/1/17 → 6/30/19

Project: Other project

Intersection of Alpha-Synuclein and Tau Contributions To Neurotoxicity

Kayed, R.

National Inst of Neurological Disorders

9/15/16 → 6/30/21

Project: Other project

Formation and Propagation of Tau Oligomeric Strains in Alzheimer's disease

Kayed, R.

National Inst on Aging

7/15/16 → 3/31/21

Project: Other project

Research Output 1997 2019

Amyloid oligomer interactions and polymorphisms: disease-relevant distinct assembly of α-synuclein and tau

Sengupta, U. & Kayed, R., Jan 1 2019, In : Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 44, 1, p. 222-223 2 p.

Research output: Contribution to journal › Comment/debate

alpha-Synuclein
Amyloid
1 Citation (Scopus)

AAV2-mediated GRP78 transfer alleviates retinal neuronal injury by downregulating ER stress and Tau oligomer formation

Ha, Y., Liu, W., Liu, H., Zhu, S., Xia, F., Gerson, J. E., Azhar, N. A., Tilton, R., Motamedi, M., Kayed, R. & Zhang, W., Sep 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 11, p. 4670-4682 13 p.

Research output: Contribution to journal › Article

Endoplasmic Reticulum Stress
Nerve Crush
Retinal Ganglion Cells
Optic Nerve
Down-Regulation
5 Citations (Scopus)

Azure C Targets and Modulates Toxic Tau Oligomers

Lo Cascio, F. & Kayed, R., Jun 20 2018, In : ACS Chemical Neuroscience. 9, 6, p. 1317-1326 10 p.

Research output: Contribution to journal › Article

Poisons
Oligomers
Alzheimer Disease
Tauopathies
Pathology
2 Citations (Scopus)

Binding and neurotoxicity mitigation of toxic tau oligomers by synthetic heparin like oligosaccharides

Wang, P., Lo Cascio, F., Gao, J., Kayed, R. & Huang, X., Jan 1 2018, In : Chemical Communications. 54, 72, p. 10120-10123 4 p.

Research output: Contribution to journal › Article

Oligosaccharides
Poisons
Oligomers
Heparin
Cytotoxicity
2 Citations (Scopus)

Elevated phospholipase D isoform 1 in Alzheimer's disease patients’ hippocampus: Relevance to synaptic dysfunction and memory deficits

Krishnan, B., Kayed, R. & Taglialatela, G., Jan 1 2018, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 4, p. 89-102 14 p.

Research output: Contribution to journal › Article

Phospholipase D
Memory Disorders
Hippocampus
Alzheimer Disease
Protein Isoforms