Rakez Kayed, PhD

  • 18589 Citations
  • 50 h-Index
19972022
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  • 12 Similar Profiles
Amyloid Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Poisons Medicine & Life Sciences
Tauopathies Medicine & Life Sciences
Oligomers Chemical Compounds
Brain Medicine & Life Sciences
Neurodegenerative Diseases Medicine & Life Sciences
Neurofibrillary Tangles Medicine & Life Sciences

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Projects 2013 2022

Research Output 1997 2019

1 Citation (Scopus)

NLRP3 inflammasome activation drives tau pathology

Ising, C., Venegas, C., Zhang, S., Scheiblich, H., Schmidt, S. V., Vieira-Saecker, A., Schwartz, S., Albasset, S., McManus, R. M., Tejera, D., Griep, A., Santarelli, F., Brosseron, F., Opitz, S., Stunden, J., Merten, M., Kayed, R., Golenbock, D. T., Blum, D., Latz, E. & 2 others, Buée, L. & Heneka, M. T., Nov 28 2019, In : Nature. 575, 7784, p. 669-673 5 p.

Research output: Contribution to journalArticle

Inflammasomes
Amyloid
Pathology
Neurofibrillary Tangles
Microglia
1 Citation (Scopus)

Tau Interacts with the C-Terminal Region of α-Synuclein, Promoting Formation of Toxic Aggregates with Distinct Molecular Conformations

Dasari, A. K. R., Kayed, R., Wi, S. & Lim, K. H., Jun 25 2019, In : Biochemistry. 58, 25, p. 2814-2821 8 p.

Research output: Contribution to journalArticle

Synucleins
Molecular Conformation
Poisons
Conformations
Agglomeration

Tau oligomers mediate aggregation of RNA-binding proteins Musashi1 and Musashi2 inducing Lamin alteration

Montalbano, M., McAllen, S., Sengupta, U., Puangmalai, N., Bhatt, N., Ellsworth, A. & Kayed, R., Dec 1 2019, In : Aging Cell. 18, 6, e13035.

Research output: Contribution to journalArticle

Open Access
Tauopathies
Lamins
RNA-Binding Proteins
Poisons
Alzheimer Disease
2 Citations (Scopus)

AAV2-mediated GRP78 transfer alleviates retinal neuronal injury by downregulating ER stress and Tau oligomer formation

Ha, Y., Liu, W., Liu, H., Zhu, S., Xia, F., Gerson, J. E., Azhar, N. A., Tilton, R., Motamedi, M., Kayed, R. & Zhang, W., Sep 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 11, p. 4670-4682 13 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Nerve Crush
Retinal Ganglion Cells
Optic Nerve
Down-Regulation