Ricardo Rajsbaum Gorodezky, PhD

  • 1803 Citations
  • 21 h-Index
20012023

Research output per year

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Research Output

  • 1803 Citations
  • 21 h-Index
  • 26 Article
  • 3 Review article
  • 2 Short survey
  • 1 Chapter
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Article
2020

VAMP8 contributes to the TRIM6-mediated type I interferon antiviral response during West Nile virus infection

Van Tol, S., Atkins, C., Bharaj, P., Johnson, K. N., Hage, A., Freiberg, A. N. & Rajsbaum, R., Jan 1 2020, In : Journal of virology. 94, 2, e01454-19.

Research output: Contribution to journalArticle

2019

Peptidoglycan-associated cyclic lipopeptide disrupts viral infectivity

Johnson, B. A., Hage, A., Kalveram, B., Mears, M., Plante, J. A., Rodriguez, S. E., Ding, Z., Luo, X., Bente, D., Bradrick, S. S., Freiberg, A. N., Popov, V., Rajsbaum, R., Rossi, S., Russell, W. K. & Menachery, V. D., Nov 1 2019, In : Journal of virology. 93, 22, e01282-19.

Research output: Contribution to journalArticle

To TRIM or not to TRIM: the balance of host-virus interactions mediated by the ubiquitin system

Hage, A. & Rajsbaum, R., Dec 1 2019, In : The Journal of general virology. 100, 12, p. 1641-1662 22 p.

Research output: Contribution to journalArticle

2018

An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

Xia, H., Luo, H., Shan, C., Muruato, A. E., Nunes, B. T. D., Medeiros, D. B. A., Zou, J., Xie, X., Giraldo, M. I., Vasconcelos, P. F. C., Weaver, S. C., Wang, T., Rajsbaum, R. & Shi, P. Y., Dec 1 2018, In : Nature communications. 9, 1, 414.

Research output: Contribution to journalArticle

67 Scopus citations

K48-linked polyubiquitination of dengue virus NS1 protein inhibits its interaction with the viral partner NS4B

Giraldo Giraldo, M., Vargas-Cuartas, O., Gallego-Gomez, J. C., Shi, P-Y., Padilla-Sanabria, L., Castaño-Osorio, J. C. & Rajsbaum Gorodezky, R., Feb 15 2018, In : Virus Research. 246, p. 1-11 11 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

The host E3-ubiquitin ligase TRIM6 ubiquitinates the Ebola virus VP35 protein and promotes virus replication

Bharaj, P., Atkins, C., Luthra, P., Giraldo Giraldo, M., Dawes, B. E., Miorin, L., Johnson, J. R., Krogan, N. J., Basler, C. F., Freiberg, A. & Rajsbaum Gorodezky, R., Sep 1 2017, In : Journal of Virology. 91, 18, e00833-17.

Research output: Contribution to journalArticle

22 Scopus citations

The TRIMendous role of TRIMs in virus-host interactions

van Tol, S., Hage, A., Giraldo, M. I., Bharaj, P. & Rajsbaum, R., Sep 2017, In : Vaccines. 5, 3, 23.

Research output: Contribution to journalArticle

22 Scopus citations
2016

The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response

Bharaj, P., Wang, Y. E., Dawes, B. E., Yun, T. E., Park, A., Yen, B., Basler, C. F., Freiberg, A., Lee, B. & Rajsbaum Gorodezky, R., Sep 1 2016, In : PLoS Pathogens. 12, 9, e1005880.

Research output: Contribution to journalArticle

26 Scopus citations
2015

Immune and non-immune responses to hepatitis C virus infection

Sun, J., Rajsbaum Gorodezky, R. & Yi, M. K., Oct 14 2015, In : World Journal of Gastroenterology. 21, 38, p. 10739-10748 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
2014

A single amino acid substitution in the novel H7N9 influenza a virus NS1 protein increases CPSF30 binding and virulence

Ayllon, J., Domingues, P., Rajsbaum, R., Miorin, L., Schmolke, M., Hale, B. G. & García-Sastre, A., Jan 1 2014, In : Journal of virology. 88, 20, p. 12146-12151 6 p.

Research output: Contribution to journalArticle

41 Scopus citations

The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type i interferon

Laurent-Rolle, M., Morrison, J., Rajsbaum, R., Macleod, J. M. L., Pisanelli, G., Pham, A., Ayllon, J., Miorin, L., Martínez-Romero, C., Tenoever, B. R. & García-Sastre, A., Sep 10 2014, In : Cell Host and Microbe. 16, 3, p. 314-327 14 p.

Research output: Contribution to journalArticle

67 Scopus citations

Unanchored K48-Linked Polyubiquitin Synthesized by the E3-Ubiquitin Ligase TRIM6 Stimulates the Interferon-IKKε Kinase-Mediated Antiviral Response

Rajsbaum, R., Versteeg, G. A., Schmid, S., Maestre, A. M., Belicha-Villanueva, A., Martínez-Romero, C., Patel, J. R., Morrison, J., Pisanelli, G., Miorin, L., Laurent-Rolle, M., Moulton, H. M., Stein, D. A., Fernandez-Sesma, A., tenOever, B. R. & García-Sastre, A., Jun 19 2014, In : Immunity. 40, 6, p. 880-895 16 p.

Research output: Contribution to journalArticle

69 Scopus citations
2013

Dengue Virus Co-opts UBR4 to Degrade STAT2 and Antagonize Type I Interferon Signaling

Morrison, J., Laurent-Rolle, M., Maestre, A. M., Rajsbaum, R., Pisanelli, G., Simon, V., Mulder, L. C. F., Fernandez-Sesma, A. & García-Sastre, A., Apr 15 2013, In : PLoS pathogens. 9, 3, e1003265.

Research output: Contribution to journalArticle

110 Scopus citations

The E3-Ligase TRIM Family of Proteins Regulates Signaling Pathways Triggered by Innate Immune Pattern-Recognition Receptors

Versteeg, G. A., Rajsbaum, R., Sánchez-Aparicio, M. T., Maestre, A. M., Valdiviezo, J., Shi, M., Inn, K. S., Fernandez-Sesma, A., Jung, J. & García-Sastre, A., Feb 21 2013, In : Immunity. 38, 2, p. 384-398 15 p.

Research output: Contribution to journalArticle

177 Scopus citations

TPL-2-ERK1/2 signaling promotes host resistance against intracellular bacterial infection by negative regulation of type I IFN production

McNab, F. W., Ewbank, J., Rajsbaum, R., Stavropoulos, E., Martirosyan, A., Redford, P. S., Wu, X., Graham, C. M., Saraiva, M., Tsichlis, P., Chaussabel, D., Ley, S. C. & O'Garra, A., Aug 15 2013, In : Journal of Immunology. 191, 4, p. 1732-1743 12 p.

Research output: Contribution to journalArticle

53 Scopus citations
2012

HERC6 is the main E3 ligase for global ISG15 conjugation in mouse cells

Oudshoorn, D., van Boheemen, S., Sánchez-Aparicio, M. T., Rajsbaum, R., García-Sastre, A. & Versteeg, G. A., Jan 17 2012, In : PloS one. 7, 1, e29870.

Research output: Contribution to journalArticle

38 Scopus citations

Species-Specific Inhibition of RIG-I Ubiquitination and IFN Induction by the Influenza A Virus NS1 Protein

Rajsbaum, R., Albrecht, R. A., Wang, M. K., Maharaj, N. P., Versteeg, G. A., Nistal-Villán, E., García-Sastre, A. & Gack, M. U., Nov 1 2012, In : PLoS pathogens. 8, 11, e1003059.

Research output: Contribution to journalArticle

153 Scopus citations

The transcription factor nfatp plays a key role in susceptibility to tb in mice

Via, L. E., Tsytsykova, A. V., Rajsbaum, R., Falvo, J. V. & Goldfeld, A. E., Jul 23 2012, In : PloS one. 7, 7, e41427.

Research output: Contribution to journalArticle

3 Scopus citations
2009

TPL-2 negatively regulates interferon-β production in macrophages and myeloid dendritic cells

Kaiser, F., Cook, D., Papoutsopoulou, S., Rajsbaum, R., Wu, X., Yang, H. T., Grant, S., Ricciardi-Castagnoli, P., Tsichlis, P. N., Ley, S. C. & O'Garra, A., Aug 31 2009, In : Journal of Experimental Medicine. 206, 9, p. 1863-1871 9 p.

Research output: Contribution to journalArticle

111 Scopus citations
2008

Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells

Rajsbaum, R., Stoye, J. P. & O'Garra, A., Mar 1 2008, In : European Journal of Immunology. 38, 3, p. 619-630 12 p.

Research output: Contribution to journalArticle

96 Scopus citations
2007

Activation-dependent intrachromosomal interactions formed by the TNF gene promoter and two distal enhancers

Tsytsykova, A. V., Rajsbaum, R., Falvo, J. V., Ligeiro, F., Neely, S. R. & Goldfeld, A. E., Oct 23 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 43, p. 16850-16855 6 p.

Research output: Contribution to journalArticle

57 Scopus citations
2006

Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals

Boonstra, A., Rajsbaum, R., Holman, M., Marques, R., Asselin-Paturel, C., Pereira, J. P., Bates, E. E. M., Akira, S., Vieira, P., Liu, Y. J., Trinchieri, G. & O'Garra, A., Dec 1 2006, In : Journal of Immunology. 177, 11, p. 7551-7558 8 p.

Research output: Contribution to journalArticle

Open Access
207 Scopus citations

NFAT5 regulates HIV-1 in primary monocytes via a highly conserved long terminal repeat site

Ranjbar, S., Tsytsykova, A. V., Lee, S. K., Rajsbaum, R., Falvo, J. V., Lieberman, J., Shankar, P. & Goldfeld, A. E., Dec 1 2006, In : PLoS pathogens. 2, 12, p. 1176-1186 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

Transactivator of transcription from HIV type 1 subtype E selectively inhibits TNF gene expression via interference with chromatin remodeling of the TNF locus

Ranjbar, S., Rajsbaum, R. & Goldfeld, A. E., Apr 1 2006, In : Journal of Immunology. 176, 7, p. 4182-4190 9 p.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations
2002

Linkage disequilibrium between HLA-DPB1 alleles and retinoid X receptor β haplotypes

Rajsbaum, R., Fici, D., Boggs, D. A., Fraser, P. A., Flores-Villanueva, P. O. & Awdeh, Z. L., Sep 1 2002, In : Human Immunology. 63, 9, p. 771-778 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2001

Polymorphism of the human retinoid X receptor β and linkage disequilibrium with HLA-DPB1

Rajsbaum, R., Fici, D., Fraser, P. A., Flores-Villanueva, P. O. & Awdeh, Z. L., Oct 22 2001, In : Tissue Antigens. 58, 1, p. 24-29 6 p.

Research output: Contribution to journalArticle

7 Scopus citations