Projects per year
Personal profile
Personal profile
Division: Vaccinology
Dr. Pyles in a Professor in the Department of Pediatrics and Microbiology & Immunology and co-Director of the UTMB Assay Development Services Division in the Galveston National Lab. He received his B.A. in Biology and Chemistry from Hanover College, Indiana. He received his PhD in Molecular Genetics and Biochemistry & Microbiology from the University of Cincinnati College of Medicine. He completed his postdoctoral fellowship in the Department of Cell Biology, Neurobiology and Anatomy at the University of Cincinnati. He joined UTMB in 2000 as part of the establishment of the Sealy Center for Vaccine Development.
Dr. Pyles’ research interests focus on the interaction of host mucosae with the bacterial communities (microbiome) and pathogens that dramatically impact human health. His career has been primarily focused on improving women’s health including study of sexually-transmitted infections. He is currently involved in preclinical and clinical studies of devices and interventions that increase ease of use and efficacy of next generation therapies. Recent work has led to the establishment of novel systems to study both vaginal and nasal human mucosae after colonization by transplanted microbiome communities.
Research interests
- COVID-19
Research Strategic Pillar Keywords
- Brain Health
- Life Span Health
- Infectious/ Immunological Health
- Metabolic Health
- Public (Social/ Physical) Health
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Projects
- 15 Completed
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The Dynamics of Nasal Bacterial Ecology and S. aureus Antagonism
6/1/16 → 5/31/20
Project: Other project
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The Dynamics of Nasal Bacterial Ecology and S. aureus Antagonism
6/1/16 → 5/31/20
Project: Other project
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The Dynamics of Nasal Bacterial Ecology and S. aureus Antagonism
6/1/16 → 5/31/20
Project: Other project
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Generation and characterization of human Fetal membrane and Decidual cell lines for reproductive biology experiments
Radnaa, E., Urrabaz-Garza, R., Elrod, N., De Castro Silva, M., Pyles, R., Han, A. & Menon, R., Mar 1 2022, In: Biology of reproduction. 106, 3, p. 568-582 15 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Inflammatory response elicited by Ureaplasma parvum colonization in human cervical epithelial, stromal, and immune cells
Tantengco, O. A. G., Kechichian, T., Vincent, K. L., Pyles, R. B., Medina, P. M. B. & Menon, R., Jan 2022, In: Reproduction. 163, 1, p. 1-10 10 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Microbiota Associated With Cholesteatoma Tissue in Chronic Suppurative Otitis Media
Frank, D. N., Magno, J. P. M., Velasco, K. J. S., Bootpetch, T. C., Salud, J. E. D., David, K. J. V., Miller, A. L., Yee, E. C., Dulnuan, H. P., Pyles, R. B., Lacuata, J. A. C., Arbizo, J. L., Kofonow, J. M., Guce, B., Mendoza, K. M. D., Robertson, C. E., Ilustre, G. M. S., Chiong, A. N. E., Lu, S. L., Tongol, E. A., & 4 others , Apr 19 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 746428.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Outbreak of coronavirus disease 2019 (COVID-19) among operating room staff of a tertiary referral center: An epidemiologic and environmental investigation
McDougal, A. N., Elhassani, D., Demaet, M. A., Shores, S., Plante, K. S., Plante, J., Pyles, R., Weaver, S. C., Williams-Bouyer, N., Tyler, B. J., Davis, H. R. & Patel, J., Mar 19 2022, In: Infection control and hospital epidemiology. 43, 3, p. 319-325 7 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The arrival of SARS-CoV-2–neutralizing antibodies in a currently available commercial immunoglobulin
Miller, A. L., Rider, N. L., Pyles, R. B., Judy, B., Xie, X., Shi, P. Y. & Ksiazek, T. G., Jun 2022, In: Journal of Allergy and Clinical Immunology. 149, 6, p. 1958-1959 2 p.Research output: Contribution to journal › Letter › peer-review
Open Access6 Scopus citations