Robert Seymour, MD, PhD

  • 604 Citations
  • 13 h-Index
20112020

Research output per year

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Research Output

  • 604 Citations
  • 13 h-Index
  • 18 Article
  • 1 Chapter

A chimeric Sindbis-based vaccine protects cynomolgus macaques against a lethal aerosol challenge of eastern equine encephalitis virus

Roy, C. J., Adams, A. P., Wang, E., Leal, G., Seymour, R. L., Sivasubramani, S. K., Mega, W., Frolov, I., Didier, P. J. & Weaver, S. C., Jan 24 2013, In : Vaccine. 31, 11, p. 1464-1470 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

A chimeric vesiculo/alphavirus is an effective alphavirus vaccine

Chattopadhyay, A., Wang, E., Seymour, R., Weaver, S. C. & Rose, J. K., Jan 1 2013, In : Journal of virology. 87, 1, p. 395-402 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

A rodent model of chikungunya virus infection in RAG1 <sup>-/-</sup> mice, with features of persistence, for vaccine safety evaluation

Seymour, R., Adams, A. P., Leal, G., Alcorn, M. D. H. & Weaver, S., Jun 26 2015, In : PLoS Neglected Tropical Diseases. 9, 6, e0003800.

Research output: Contribution to journalArticle

15 Scopus citations

Attenuation of chikungunya virus vaccine strain 181/clone 25 is determined by two amino acid substitutions in the e2 envelope glycoprotein

Gorchakov, R., Wang, E., Leal, G., Forrester, N. L., Plante, K., Rossi, S. L., Partidos, C. D., Adams, A. P., Seymour, R. L., Weger, J., Borland, E. M., Sherman, M. B., Powers, A. M., Osorio, J. E. & Weaver, S. C., Jun 1 2012, In : Journal of virology. 86, 11, p. 6084-6096 13 p.

Research output: Contribution to journalArticle

85 Scopus citations

Chikungunya vaccine candidate is highly attenuated and protects nonhuman primates against telemetrically monitored disease following a single dose

Roy, C. J., Adams, A. P., Wang, E., Plante, K., Gorchakov, R., Seymour, R. L., Vinet-Oliphant, H. & Weaver, S. C., Jun 15 2014, In : Journal of Infectious Diseases. 209, 12, p. 1891-1899 9 p.

Research output: Contribution to journalArticle

59 Scopus citations

Collaborative study for the characterization of a chikungunya virus RNA reference reagent for use in nucleic acid testing

The Chikungunya virus Collaborative Study Group, Nov 1 2015, In : Vox Sanguinis. 109, 4, p. 312-318 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Cross-protective immunity against o'nyong-nyong virus afforded by a novel recombinant chikungunya vaccine

Partidos, C. D., Paykel, J., Weger, J., Borland, E. M., Powers, A. M., Seymour, R., Weaver, S. C., Stinchcomb, D. T. & Osorio, J. E., Jun 29 2012, In : Vaccine. 30, 31, p. 4638-4643 6 p.

Research output: Contribution to journalArticle

49 Scopus citations

Extended Preclinical Safety, Efficacy and Stability Testing of a Live-attenuated Chikungunya Vaccine Candidate

Plante, K. S., Rossi, S., Bergren, N. A., Seymour, R. & Weaver, S., Sep 4 2015, In : PLoS Neglected Tropical Diseases. 9, 9, e0004007.

Research output: Contribution to journalArticle

23 Scopus citations

Host gene expression profiles in ferrets infected with genetically distinct henipavirus strains

Leon, A. J., Borisevich, V., Boroumand, N., Seymour, R., Nusbaum, R., Escaffre, O., Xu, L., Kelvin, D. J. & Rockx, B., Mar 14 2018, In : PLoS Neglected Tropical Diseases. 12, 3, e0006343.

Research output: Contribution to journalArticle

4 Scopus citations

Niakha virus: A novel member of the family Rhabdoviridae isolated from phlebotomine sandflies in Senegal

Vasilakis, N., Widen, S., Mayer, S. V., Seymour, R., Wood, T. G., Popov, V., Guzman, H., Travassos da Rosa, A. P. A., Ghedin, E., Holmes, E. C., Walker, P. J. & Tesh, R. B., Sep 1 2013, In : Virology. 444, 1-2, p. 80-89 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Novel chikungunya vaccine candidate with an ires-based attenuation and host range alteration mechanism

Plante, K., Wang, E., Partidos, C. D., Weger, J., Gorchakov, R., Tsetsarkin, K., Borland, E. M., Powers, A. M., Seymour, R., Stinchcomb, D. T., Osorio, J. E., Frolov, I. & Weaver, S. C., Jul 1 2011, In : PLoS pathogens. 7, 7, e1002142.

Research output: Contribution to journalArticle

113 Scopus citations

Novel insect-specific Eilat virus-based chimeric vaccine candidates provide durable, mono- and multivalent, single-dose protection against lethal alphavirus challenge

Erasmus, J. H., Seymour, R. L., Kaelber, J. T., Kim, D. Y., Leal, G., Sherman, M. B., Frolov, I., Chiu, W., Weaver, S. C. & Nasar, F., Feb 1 2018, In : Journal of virology. 92, 4, e01274-17.

Research output: Contribution to journalArticle

13 Scopus citations

Preclinical Evaluation of a Live Attenuated Chikungunya Vaccine

Livengood, J. A., Partidos, C. D., Plante, K., Seymour, R., Gorchakov, R., Varga, L., Paykel, J., Weger, J., Haller, A., Stinchcomb, D. T., Osorio, J. & Weaver, S., May 7 2012, In : Procedia in Vaccinology. 6, p. 141-149 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Probing the attenuation and protective efficacy of a candidate chikungunya virus vaccine in mice with compromised interferon (IFN) signaling

Partidos, C. D., Weger, J., Brewoo, J., Seymour, R., Borland, E. M., Ledermann, J. P., Powers, A. M., Weaver, S. C., Stinchcomb, D. T. & Osorio, J. E., Apr 5 2011, In : Vaccine. 29, 16, p. 3067-3073 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Recombinant Isfahan virus and vesicular stomatitis virus vaccine vectors provide durable, multivalent, single-dose protection against lethal alphavirus challenge

Nasar, F., Matassov, D., Seymour, R., Latham, T., Gorchakov, R. V., Nowak, R. M., Leal, G., Hamm, S., Eldridge, J. H., Tesh, R. B., Clarke, D. K. & Weaver, S., Apr 1 2017, In : Journal of Virology. 91, 8, e01729-16.

Research output: Contribution to journalArticle

7 Scopus citations

The role of innate versus adaptive immune responses in a mouse model of O'Nyong-Nyong virus infection

Seymour, R. L., Rossi, S. L., Bergren, N. A., Plante, K. S. & Weaver, S. C., Jun 1 2013, In : American Journal of Tropical Medicine and Hygiene. 88, 6, p. 1170-1179 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Vector-Borne Transmission Imposes a Severe Bottleneck on an RNA Virus Population

Forrester, N. L., Guerbois, M., Seymour, R. L., Spratt, H. & Weaver, S. C., Sep 1 2012, In : PLoS pathogens. 8, 9, e1002897.

Research output: Contribution to journalArticle

69 Scopus citations

Venezuelan equine encephalitis

Seymour, R. & Weaver, S., Jan 1 2016, Neurotropic Viral Infections: Volume 1: Neurotropic RNA Viruses. Springer International Publishing, p. 205-227 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

“Submergence” of Western equine encephalitis virus: Evidence of positive selection argues against genetic drift and fitness reductions

Bergren, N. A., Haller, S., Rossi, S. L., Seymour, R. L., Huang, J., Miller, A. L., Bowen, R. A., Hartman, D. A., Brault, A. C. & Weaver, S. C., Jan 1 2020, In : PLoS pathogens. 16, 2, e1008102.

Research output: Contribution to journalArticle

Open Access