Projects per year
Personal profile
Personal profile
Division: Clinical and Experimental Immunology and Infectious Disease
Dr. Garofalo is Professor of Pediatrics, Microbiology and Immunology, Pharmacology and Toxicology. He received his undergraduate degree from Maturita’ Classica, Liceo Ginnasio G. Carducci, Milano, Italy and his MD at the University of the Studies of Milano in Italy. He completed his residency in pediatrics at Istituto di Scienze Biomediche, Ospedal S. Paolo, University of the Studies of Milano and his postdoctoral fellowship in Infectious Disease at the Children’s Hospital, State University of New York at Buffalo.
He is Vice Chair for Research and Director of the Division of Clinical and Experimental Immunology & Infectious Disease, in the Department of Pediatrics at UTMB. He is a pediatrician-scientist with more than twenty years of NIH, NASA, and DoD-funded clinical, translational and basic research on bronchiolitis. Dr. Garofalo is internationally recognized for his work on respiratory syncytial virus, with expertise in murine models of paramyxovirus infections and mouse immunology. He has mentored disadvantaged and underrepresented minority, pre and post-baccalaureate students and has experience in heading multidisciplinary teams. As a pediatrician, his expertise and funded research is in the areas of lung mucosal immunology, pathogenesis of respiratory infections, and genetic and environmental determinants of airway pathophysiology in children. Using comprehensive proteomics approaches he has characterized a novel oxidative-driven pathway of airway inflammation in infants. He has also led research teams in the area of lung diseases, including one of the CTSA multidisciplinary translational teams at UTMB, and he is co-PI of the NIAID-funded Program Project “Signaling in Airway Inflammation”. He was recently the Project Leader of NASA funded research “Effect of Spaceflight on Innate Immunity to Respiratory Viral Infections, Mouse Immunology-2”, from Space Shuttle Discovery, STS-133, and the Project Leader on NASA research tissue sharing project “Effect of Spaceflight on Lung Gene and Protein Expression Profiles” from the last mission of Space Shuttle Atlantis, STS-135
Research interests
- Covid-19
- ITS
- Translational Science
Research Strategic Pillar Keywords
- Life Span Health
- Specialized Health
Fingerprint
- 1 Similar Profiles
Network
-
Innate Inhibitory Activity and Anti-SARS-CoV-2 Antibodies in Human Milk
11/20/20 → 11/19/23
Project: Other project
-
Innate Inhibitory Activity and Anti-SARS-CoV-2 Antibodies in Human Milk
11/12/20 → 11/11/23
Project: Other project
-
-
-
-
Antiviral activity of extracellular vesicles derived from respiratory syncytial virus-infected airway epithelial cells
Corsello, T., Qu, Y., Ivanciuc, T., Garofalo, R. P. & Casola, A., Aug 12 2022, In: Frontiers in immunology. 13, p. 1-11 11 p., 886701.Research output: Contribution to journal › Article › peer-review
Open Access -
Hydrogen Sulfide Donor GYY4137 Rescues NRF2 Activation in Respiratory Syncytial Virus Infection
de Mello, A. H., Liu, T., Garofalo, R. P. & Casola, A., Jul 2022, In: Antioxidants. 11, 7, 1410.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Lack of type I interferon signaling ameliorates respiratory syncytial virus-induced lung inflammation and restores antioxidant defenses
Ansar, M., Qu, Y., Ivanciuc, T., Garofalo, R. P. & Casola, A., Jan 2022, In: Antioxidants. 11, 1, 67.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
NRF2 Regulates Cystathionine Gamma-Lyase Expression and Activity in Primary Airway Epithelial Cells Infected with Respiratory Syncytial Virus
Jamaluddin, M., Haas de Mello, A., Tapryal, N., Hazra, T. K., Garofalo, R. P. & Casola, A., Aug 2022, In: Antioxidants. 11, 8, 1582.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Parent tRNA Modification Status Determines the Induction of Functional tRNA-Derived RNA by Respiratory Syncytial Virus Infection
Choi, E-J., Wu, W., Zhang, K., Yuan, X., Deng, J., Ismail, D., Buck, D. L., Thomason, K. S., Garofalo, R. P., Zhang, S. & Bao, X., Dec 24 2022, In: Viruses. 15, 1Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
-
Family health; UTMB set to research breast milk's COVID-19 antibodies
1/28/21
1 item of Media coverage
Press/Media: Expert Comment
-
UTMB receives 3-year grant to research breast milk’s COVID-19 antibodies
1/26/21
2 items of Media coverage
Press/Media: Expert Comment