Roberto P. Garofalo, MD

MD, Vice Chair for Research, Pediatrics, Director, CEIID, Vice Chair, Research

  • 7965 Citations
  • 55 h-Index
1990 …2023
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Personal profile

Personal profile

Division: Clinical and Experimental Immunology and Infectious Disease

Dr. Garofalo is Professor of Pediatrics, Microbiology and Immunology, Pharmacology and Toxicology.  He received his undergraduate degree from Maturita’ Classica, Liceo Ginnasio G. Carducci, Milano, Italy and his MD at the University of the Studies of Milano in Italy. He completed his residency in pediatrics at Istituto di Scienze Biomediche, Ospedal S. Paolo, University of the Studies of Milano and his postdoctoral fellowship in Infectious Disease at the Children’s Hospital, State University of New York at Buffalo.

He is Vice Chair for Research and Director of the Division of Clinical and Experimental Immunology & Infectious Disease, in the Department of Pediatrics at UTMB. He is a pediatrician-scientist with more than twenty years of NIH, NASA, and DoD-funded clinical, translational and basic research on bronchiolitis. Dr. Garofalo is internationally recognized for his work on respiratory syncytial virus, with expertise in murine models of paramyxovirus infections and mouse immunology. He has mentored disadvantaged and underrepresented minority, pre and post-baccalaureate students and has experience in heading multidisciplinary teams. As a pediatrician, his expertise and funded research is in the areas of lung mucosal immunology, pathogenesis of respiratory infections, and genetic and environmental determinants of airway pathophysiology in children. Using comprehensive proteomics approaches he has characterized a novel oxidative-driven pathway of airway inflammation in infants. He has also led research teams in the area of lung diseases, including one of the CTSA multidisciplinary translational teams at UTMB, and he is co-PI of the NIAID-funded Program Project “Signaling in Airway Inflammation”.  He was recently the Project Leader of NASA funded research “Effect of Spaceflight on Innate Immunity to Respiratory Viral Infections, Mouse Immunology-2”, from Space Shuttle Discovery, STS-133, and the Project Leader on NASA research tissue sharing project “Effect of Spaceflight on Lung Gene and Protein Expression Profiles” from the last mission of Space Shuttle Atlantis, STS-135

Fingerprint Dive into the research topics where Roberto P. Garofalo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 28 Similar Profiles
Respiratory Syncytial Viruses Medicine & Life Sciences
Respiratory Syncytial Virus Infections Medicine & Life Sciences
Metapneumovirus Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences
Chemokines Medicine & Life Sciences
viruses Agriculture & Biology
Cytokines Medicine & Life Sciences
Bronchiolitis Medicine & Life Sciences

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Projects 2010 2023

Research Output 1990 2019

  • 7965 Citations
  • 55 h-Index
  • 140 Article
  • 2 Chapter
  • 1 Review article

Antiviral and immunomodulatory activity of silver nanoparticles in experimental rsv infection

Morris, D., Ansar, M., Speshock, J., Ivanciuc, T., Qu, Y., Casola, A. & Garofalo, R., Aug 1 2019, In : Viruses. 11, 8, 732.

Research output: Contribution to journalArticle

Open Access
Respiratory Syncytial Viruses
Silver
Nanoparticles
Antiviral Agents
Respiratory Syncytial Virus Infections
Cystathionine
Lyases
Virus Diseases
Smoke
Tobacco
5 Citations (Scopus)

Central role of the NF-κB pathway in the Scgb1a1-expressing epithelium in mediating respiratory syncytial virus-induced airway inflammation

Tian, B., Yang, J., Zhao, Y., Ivanciuc, T., Sun, H., Wakamiya, M., Garofalo, R. & Brasier, A. R., Jun 1 2018, In : Journal of Virology. 92, 11, e00441-18.

Research output: Contribution to journalArticle

respiratory mucosa
Respiratory Syncytial Virus Infections
Respiratory Syncytial Viruses
Knockout Mice
Interferons

Exchange Proteins Directly Activated by cAMP and Their Roles in Respiratory Syncytial Virus Infection

Choi, E-J., Ren, Y., Chen, Y., Liu, S., Wu, W., Ren, J., Wang, P., Garofalo, R., Zhou, J. & Bao, X., Nov 15 2018, In : Journal of Virology. 92, 22

Research output: Contribution to journalArticle

Respiratory Syncytial Virus Infections
Respiratory Syncytial Viruses
viruses
virus replication
infection
2 Citations (Scopus)

Lysines and Arginines play non-redundant roles in mediating chemokine-glycosaminoglycan interactions

Joseph, P. R. B., Sawant, K. V., Iwahara, J., Garofalo, R., Desai, U. R. & Rajarathnam, K., Dec 1 2018, In : Scientific Reports. 8, 1, 12289.

Research output: Contribution to journalArticle

Glycosaminoglycans
Chemokines
Lysine
Arginine
Carrier Proteins