Roberto P. Garofalo, MD

MD, Vice Chair for Research, Pediatrics, Director, CEIID, Vice Chair, Research

  • 8358 Citations
  • 56 h-Index
1990 …2020

Research output per year

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Personal profile

Personal profile

Division: Clinical and Experimental Immunology and Infectious Disease

Dr. Garofalo is Professor of Pediatrics, Microbiology and Immunology, Pharmacology and Toxicology.  He received his undergraduate degree from Maturita’ Classica, Liceo Ginnasio G. Carducci, Milano, Italy and his MD at the University of the Studies of Milano in Italy. He completed his residency in pediatrics at Istituto di Scienze Biomediche, Ospedal S. Paolo, University of the Studies of Milano and his postdoctoral fellowship in Infectious Disease at the Children’s Hospital, State University of New York at Buffalo.

He is Vice Chair for Research and Director of the Division of Clinical and Experimental Immunology & Infectious Disease, in the Department of Pediatrics at UTMB. He is a pediatrician-scientist with more than twenty years of NIH, NASA, and DoD-funded clinical, translational and basic research on bronchiolitis. Dr. Garofalo is internationally recognized for his work on respiratory syncytial virus, with expertise in murine models of paramyxovirus infections and mouse immunology. He has mentored disadvantaged and underrepresented minority, pre and post-baccalaureate students and has experience in heading multidisciplinary teams. As a pediatrician, his expertise and funded research is in the areas of lung mucosal immunology, pathogenesis of respiratory infections, and genetic and environmental determinants of airway pathophysiology in children. Using comprehensive proteomics approaches he has characterized a novel oxidative-driven pathway of airway inflammation in infants. He has also led research teams in the area of lung diseases, including one of the CTSA multidisciplinary translational teams at UTMB, and he is co-PI of the NIAID-funded Program Project “Signaling in Airway Inflammation”.  He was recently the Project Leader of NASA funded research “Effect of Spaceflight on Innate Immunity to Respiratory Viral Infections, Mouse Immunology-2”, from Space Shuttle Discovery, STS-133, and the Project Leader on NASA research tissue sharing project “Effect of Spaceflight on Lung Gene and Protein Expression Profiles” from the last mission of Space Shuttle Atlantis, STS-135

Research interests

  • Covid-19

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Projects

Research Output

  • 8358 Citations
  • 56 h-Index
  • 131 Article
  • 9 Review article
  • 3 Comment/debate
  • 2 Chapter

A polymorphism in the catalase gene promoter confers protection against severe RSV bronchiolitis

Chambliss, J. M., Ansar, M., Kelley, J. P., Spratt, H., Garofalo, R. P. & Casola, A., Jan 3 2020, In : Viruses. 12, 1, , 57.

Research output: Contribution to journalArticle

Open Access
  • Increased Lung Catalase Activity Confers Protection Against Experimental RSV Infection

    Ansar, M., Ivanciuc, T., Garofalo, R. P. & Casola, A., Dec 1 2020, In : Scientific reports. 10, 1, 3653.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    Antiviral and immunomodulatory activity of silver nanoparticles in experimental rsv infection

    Morris, D., Ansar, M., Speshock, J., Ivanciuc, T., Qu, Y., Casola, A. & Garofalo, R., Aug 1 2019, In : Viruses. 11, 8, 732.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    Cystathionine γ-lyase deficiency enhances airway reactivity and viral-induced disease in mice exposed to side-stream tobacco smoke

    Ivanciuc, T., Sbrana, E., Casola, A. & Garofalo, R. P., Jul 1 2019, In : Pediatric Research. 86, 1, p. 39-46 8 p.

    Research output: Contribution to journalArticle

  • Central role of the NF-κB pathway in the Scgb1a1-expressing epithelium in mediating respiratory syncytial virus-induced airway inflammation

    Tian, B., Yang, J., Zhao, Y., Ivanciuc, T., Sun, H., Wakamiya, M., Garofalo, R. & Brasier, A. R., Jun 1 2018, In : Journal of Virology. 92, 11, e00441-18.

    Research output: Contribution to journalArticle

  • 10 Scopus citations