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Research Strategic Pillar
The Chief Research Officer, has determined that UTMB research should be prioritized into six health communities. This researcher has received the following badge(s):
Personal profile
Division: Clinical and Experimental Immunology and Infectious Disease
Dr. Garofalo is Professor of Pediatrics, Microbiology and Immunology, Pharmacology and Toxicology.? He received his undergraduate degree from Maturita’ Classica, Liceo Ginnasio G. Carducci, Milano, Italy and his MD at the University of the Studies of Milano in Italy. He completed his residency in pediatrics at Istituto di Scienze Biomediche, Ospedal S. Paolo, University of the Studies of Milano and his postdoctoral fellowship in Infectious Disease at the Children’s Hospital, State University of New York at Buffalo.
He is Vice Chair for Research and Director of the Division of Clinical and Experimental Immunology & Infectious Disease, in the Department of Pediatrics at UTMB. He is a pediatrician-scientist with more than twenty years of NIH, NASA, and DoD-funded clinical, translational and basic research on bronchiolitis. Dr. Garofalo is internationally recognized for his work on respiratory syncytial virus, with expertise in murine models of paramyxovirus infections and mouse immunology. He has mentored disadvantaged and underrepresented minority, pre and post-baccalaureate students and has experience in heading multidisciplinary teams. As a pediatrician, his expertise and funded research is in the areas of lung mucosal immunology, pathogenesis of respiratory infections, and genetic and environmental determinants of airway pathophysiology in children. Using comprehensive proteomics approaches he has characterized a novel oxidative-driven pathway of airway inflammation in infants. He has also led research teams in the area of lung diseases, including one of the CTSA multidisciplinary translational teams at UTMB, and he is co-PI of the NIAID-funded Program Project “Signaling in Airway Inflammation”.? He was recently the Project Leader of NASA funded research “Effect of Spaceflight on Innate Immunity to Respiratory Viral Infections, Mouse Immunology-2”, from Space Shuttle Discovery, STS-133, and the Project Leader on NASA research tissue sharing project “Effect of Spaceflight on Lung Gene and Protein Expression Profiles” from the last mission of Space Shuttle Atlantis, STS-135
Research Strategic Pillar Keywords
- Life Span Health
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Collaborations and top research areas from the last five years
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Extracellular Vesicles (EVs) Innate Immune Cargo in Respiratory Viral Infections
Garofalo, R. P. (PI)
National Institute of Allergy and Infectious Diseases ( Award #5R21AI17608502)
6/18/24 → 4/30/26
Project: Research project
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Innate Inhibitory Activity and Anti-SARS-CoV-2 Antibodies in Human Milk
Garofalo, R. P. (PI)
11/12/20 → 11/11/23
Project: Research project
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Admin Core
Garofalo, R. P. (PI)
National Institute of Allergy and Infectious Diseases ( Award #5P01AI06288515)
7/25/18 → 6/30/23
Project: Research project
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Role of the endogenous gasotransmitter H2S in ETS-mediated airway disease
Garofalo, R. P. (PI)
National Institute of Environmental Health Sciences ( Award #5R21ES02678202)
6/1/16 → 5/31/19
Project: Research project
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Advanced photohydrolysis technology demonstrates rapid inactivation of aerosolized SARS-CoV-2 and efficacy against other respiratory viral pathogens
Peel, J. E., Jardinella, E., Qu, Y., Plante, J. A., Mitchell, B. M., Walker, J. L., Garofalo, R. P., Weaver, S. C., Plante, K. S., Brasel, T. & Lawrence, W. S., Jun 2025, In: American Journal of Infection Control. 53, 6, p. 726-728 3 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Analysis of Proteins and Piwi-Interacting RNA Cargo of Extracellular Vesicles (EVs) Isolated from Human Nose Organoids and Nasopharyngeal Secretions of Children with RSV Infections
Corsello, T., Dillman, N., Zhao, Y., Ivanciuc, T., Liu, T., Casola, A. & Garofalo, R. P., Jun 2025, In: Viruses. 17, 6, 764.Research output: Contribution to journal › Article › peer-review
Open Access -
Rapid In Vivo Screening of Monoclonal Antibody Cocktails Using Hydrodynamic Delivery of DNA-Encoded Modified Antibodies
Fausther-Bovendo, H., Babuadze, G., Ivanciuc, T., Kalveram, B., Qu, Y., Choi, J., McGeer, A., Ostrowski, M., Mubareka, S., Patel, A., Garofalo, R. P., Kozak, R. & Kobinger, G. P., Mar 2025, In: Biomedicines. 13, 3, 637.Research output: Contribution to journal › Article › peer-review
Open Access -
Respiratory syncytial virus downregulates the airway aryl hydrocarbon receptor pathway: implication for the development of a novel therapeutic target
de Mello, A. H., Qu, Y., Liu, T., Garofalo, R. P. & Casola, A., Dec 2025, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 329, 6, p. L716-L731Research output: Contribution to journal › Article › peer-review
Open Access -
Role of Hypoxia-Inducible Factors in Respiratory Syncytial Virus Infection-Associated Lung Disease
Morris, D. R., Qu, Y., Haas de Mello, A., Jones-Hall, Y. L., Liu, T., Weglarz, M., Ivanciuc, T., Garofalo, R. P. & Casola, A., Mar 29 2025, In: International journal of molecular sciences. 26, 7, 3182.Research output: Contribution to journal › Article › peer-review
Open Access