Projects per year
Personal profile
Research Strategic Pillar
The Chief Research Officer, has determined that UTMB research should be prioritized into six health communities. This researcher has received the following badge(s):
Research interests
Dr. Salim Hayek is Professor and Chair of the Department of Internal Medicine at the University of Texas Medical Branch, where he holds the Edward Randall and Edward Randall Jr. Distinguished Chair in Internal Medicine. He is a cardiologist and NIH-funded physician-scientist whose research sits at the intersection of cardiovascular and kidney disease, with a focus on inflammation, novel biomarkers, and precision approaches to risk prediction.
His translational program centers on soluble urokinase plasminogen activator receptor (suPAR) as a driver of cardiovascular, kidney, and immune-mediated disease. Work from his group has helped establish suPAR as a prognostic biomarker across cardiovascular disease, chronic kidney disease, COVID-19, and cancer therapy-related cardiotoxicity, and has informed mechanistic studies of its role in vascular and renal injury. He currently leads an R01 from the NHLBI examining the role of suPAR at the cardiovascular-kidney interface.
His broader research portfolio uses large cohorts, high-throughput proteomics, and routinely collected clinical data to identify patients at risk for cardiovascular and kidney complications, refine therapy, and guide preventive strategies. He has long-standing collaborations with the Emory Cardiovascular Biobank, the University of Michigan Precision Health initiative, and the University of Michigan George O'Brien Kidney Translational Resource Center, where he directs the Research Development Core. He also serves as Chair of the American Heart Association's Cardio-Oncology Subcommittee and as Editorial Lead for Cardio-Oncology at the American College of Cardiology.
Before joining UTMB, Dr. Hayek spent nearly a decade at the University of Michigan's Frankel Cardiovascular Center, where he founded the cardio-oncology program and served as Medical Director of the Cardiovascular Center Clinics. He has authored over 200 peer-reviewed publications, many in high-impact journals, with research recognized through the American College of Cardiology Douglas P. Zipes Distinguished Young Scientist Award, the American Heart Association Samuel A. Levine Early Career Investigator Award, the Juanita L. Merchant Early Career Endowment, and the Jerome W. Conn Award for Excellence in Research. He was elected to the American Society for Clinical Investigation in 2026.
Education/Academic qualification
Cardiology (Clinical Investigator Track), Cardiology Fellowship, Emory University
2013 → 2018
Internal Medicine, Internal Medicine Residency, Emory University
2010 → 2013
Cardiac Development and Differentiation, Postdoctoral Fellowship, University of Ottawa
2008 → 2010
Doctor of Medicine, American University of Beirut Beirut LB
… → 2008
Biology, Bachelor of Science, American University of Beirut
2002 → …
Research interests
- Soluble urokinase plasminogen activator receptor (suPAR)
- Cardio-oncology
- Cardiovascular-kidney disease
- Inflammation
- Biomarkers
- Proteomics
- Precision medicine
- Risk prediction
- Heart failure
- Immune checkpoint inhibitor myocarditis
- Chronic kidney disease
Research Strategic Pillar Keywords
- Specialized Health
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Role of SuPAR in the Intersection between Cardiovascular and Kidney Disease
Hayek, S. (PI)
National Heart, Lung and Blood Institute ( Award #7R01HL15338405)
9/24/24 → 8/31/26
Project: Research project
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University of Michigan O'Brien Kidney Translational Resource Center (MKTC)
Hayek, S. (PI)
University of Michigan ( Award #5U54DK13731402)
3/1/24 → 9/30/24
Project: Research project
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Atrial Fibrillation After Stem Cell Transplantation
Hayek, S. S. & Riwes, M., Feb 2026, In: JACC: CardioOncology. 8, 1, p. 28-30 3 p.Research output: Contribution to journal › Editorial › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Combination cardiometabolic therapy in type 2 diabetes: optimizing SGLT2 inhibitor and GLP‑1 receptor agonist use
Porterfield, L., Nadeem, S., Swanson, D., Hayek, S. S. & Vaughan, E. M., Jul 18 2026, In: Current Atherosclerosis Reports. 28, 1, 73.Research output: Contribution to journal › Review article › peer-review
Open Access -
Diagnosis and Management of Cardiovascular Adverse Effects of Targeted Oncology Therapies: Bruton's Tyrosine Kinase, Immune Checkpoint, and Vascular Endothelial Growth Factor Inhibitors: 2025 ACC Concise Clinical Guidance: A Report of the American College of Cardiology Solution Set Oversight Committee
Ganatra, S., Barac, A., Armenian, S., Cambareri, C., Denlinger, C. S., Dent, S. F., Hayek, S., Ky, B., Leja, M., Lucas, C. H., Makwana, B., Palaskas, N. L. & Vo, J. B., Feb 10 2026, In: Journal of the American College of Cardiology. 87, 5, p. 654-682 29 p.Research output: Contribution to journal › Article › peer-review
20 Link opens in a new tab Scopus citations -
Effectiveness and safety of immunotherapy in advanced NSCLC with pericardial effusions: a global retrospective multicenter study
El Zarif, T., Abou Alaiwi, S., Nassar, A. H., Gariazzo, E., Santo, V., Garbo, E., Aldea, M., Paoloni, F., Pannu, S., Semaan, K., Chehab, O., Hoballah, M., Navani, V., Gao, Y., Meyers, D., Stukalin, I., Mittra, A., Li, M., Jones, N. & Grynberg, S. & 32 others, , Sep 2026, In: Oncologist. 31, 9, oyag277.Research output: Contribution to journal › Article › peer-review
Open Access -
Immune checkpoint inhibitor-associated myocarditis: A novel risk score
International ICI-Myocarditis Registry, Mar 1 2026, In: European Heart Journal. 47, 9, p. 1050-1062 13 p.Research output: Contribution to journal › Article › peer-review
Open Access57 Link opens in a new tab Scopus citations
Activities
- 11 Other
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Reviewer, NIH Environmental Determinants of Disease (EDD) Study Section
Hayek, S. (Recipient)
2025Activity: Other activity types › Other
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Reviewer, Department of Defense Peer Reviewed Medical Research Program (PRMRP)
Hayek, S. (Recipient)
2025Activity: Other activity types › Other
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Chair, American Heart Association Cardio-Oncology Committee
Hayek, S. (Recipient)
2023 → …Activity: Other activity types › Other
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Editorial Consultant, JACC: CardioOncology
Hayek, S. (Recipient)
2022 → …Activity: Other activity types › Other
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Vice-Chair, American Heart Association Cardio-Oncology Committee
Hayek, S. (Recipient)
2021 → 2022Activity: Other activity types › Other
Prizes
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American Heart Association Samuel A. Levine Early Career Clinical Investigator Award
Hayek, S. (Recipient), 2019
Prize: Honors (including medals and awards)
-
American Heart Association Sarns Innovative Excellence Award
Hayek, S. (Recipient), 2021
Prize: Honors (including medals and awards)
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Andersen Heart of a Champion Prize
Hayek, S. (Recipient), 2021
Prize: Honors (including medals and awards)
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Douglas P. Zipes Distinguished Young Scientist Award, American College of Cardiology
Hayek, S. (Recipient), 2018
Prize: Honors (including medals and awards)
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Edward Randall and Edward Randall Jr. Distinguished Chair in Internal Medicine
Hayek, S. (Recipient), 2024
Prize: Honors (including medals and awards)