Sara Dann-Grice, PhD

  • 1203 Citations
  • 22 h-Index
20002020

Research output per year

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Research Output

  • 1203 Citations
  • 22 h-Index
  • 34 Article
  • 3 Review article
  • 1 Letter
  • 1 Short survey
2020

New host-directed therapeutics for the treatment of Clostridioides difficile infection

Andersson, J. A., Peniche, A. G., Galindo, C. L., Boonma, P., Sha, J., Luna, R. A., Savidge, T. C., Chopra, A. K. & Dann, S. M., Mar 1 2020, In : mBio. 11, 2, e00053-20.

Research output: Contribution to journalArticle

Open Access
2019

Dissemination of non-typhoidal Salmonella during Plasmodium chabaudi infection affects anti-malarial immunity

Alamer, E., Carpio, V. H., Ibitokou, S. A., Kirtley, M. L., Phoenix, I. R., Opata, M. M., Wilson, K. D., Cong, Y., Dann, S. M., Chopra, A. K. & Stephens, R., Jul 1 2019, In : Parasitology research. 118, 7, p. 2277-2285 9 p.

Research output: Contribution to journalArticle

Interleukin-33 Promotes REG3γ Expression in Intestinal Epithelial Cells and Regulates Gut Microbiota

Xiao, Y., Huang, X., Zhao, Y., Chen, F., Sun, M., Yang, W., Chen, L., Yao, S., Peniche, A., Dann, S. M., Sun, J., Golovko, G., Fofanov, Y., Miao, Y., Liu, Z., Chen, D. & Cong, Y., 2019, In : CMGH. 8, 1, p. 21-36 16 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

RORγt represses IL-10 production in Th17 cells to maintain their pathogenicity in inducing intestinal inflammation

Sun, M., He, C., Chen, L., Yang, W., Wu, W., Chen, F., Cao, A. T., Yao, S., Dann, S. M., Dhar, T. G. M., Salter-Cid, L., Zhao, Q., Liu, Z. & Cong, Y., Jan 1 2019, In : Journal of Immunology. 202, 1, p. 79-92 14 p.

Research output: Contribution to journalArticle

4 Scopus citations
2018

Aging impairs protective host defenses against Clostridioides (Clostridium) difficile infection in mice by suppressing neutrophil and IL-22 mediated immunity

Peniche-Trujillo, A-G., Spinler, J. K., Boonma, P., Savidge, T. C. & Dann-Grice, S., Dec 1 2018, In : Anaerobe. 54, p. 83-91 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Combating multidrug-resistant pathogens with host-directed nonantibiotic therapeutics

Andersson, J. A., Sha, J., Kirtley, M. L., Reyes, E., Fitts, E. C., Dann-Grice, S. & Chopra, A., Jan 1 2018, In : Antimicrobial Agents and Chemotherapy. 62, 1, e01943.

Research output: Contribution to journalArticle

6 Scopus citations

Giardia infection of the small intestine induces chronic colitis in genetically susceptible hosts

Dann-Grice, S., Le, C. H. Y., Hanson, E. M., Ross, M. C. & Eckmann, L., Jul 15 2018, In : Journal of Immunology. 201, 2, p. 548-559 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis

Sun, M., Wu, W., Chen, L., Yang, W., Huang, X., Ma, C., Chen, F., Xiao, Y., Zhao, Y., Ma, C., Yao, S., Carpio, V. H., Dann, S. M., Zhao, Q., Liu, Z. & Cong, Y., Dec 1 2018, In : Nature Communications. 9, 1, 3555.

Research output: Contribution to journalArticle

38 Scopus citations

Neutrophils promote amphiregulin production in intestinal epithelial cells through TGF-β and contribute to intestinal homeostasis

Chen, F., Yang, W., Huang, X., Cao, A. T., Bilotta, A. J., Xiao, Y., Sun, M., Chen, L., Ma, C., Liu, X., Liu, C. G., Yao, S., Dann, S. M., Liu, Z. & Cong, Y., Oct 15 2018, In : Journal of Immunology. 201, 8, p. 2492-2501 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

GABA-producing Bifidobacterium dentium modulates visceral sensitivity in the intestine

Pokusaeva, K., Johnson, C., Luk, B., Uribe, G., Fu, Y., Oezguen, N., Matsunami, R. K., Lugo, M., Major, A., Mori-Akiyama, Y., Hollister, E. B., Dann-Grice, S., Shi, X-Z., Engler, D. A., Savidge, T. & Versalovic, J., Jan 1 2017, In : Neurogastroenterology and Motility. 29, 1, e12904.

Research output: Contribution to journalArticle

47 Scopus citations

Nextgeneration probiotics targeting Clostridium difficile through precursor-directed antimicrobial biosynthesis

Spinler, J. K., Auchtung, J., Brown, A., Boonma, P., Oezguen, N., Ross, C. L., Luna, R. A., Runge, J., Versalovic, J., Peniche, A., Dann, S. M., Britton, R. A., Haag, A. & Savidge, T. C., Jan 1 2017, In : Infection and immunity. 85, 10, e00303-17.

Research output: Contribution to journalArticle

14 Scopus citations

The association between gaba-modulators and clostridium difficile infection - A matched retrospective case-control study

Ström, J., Tham, J., Månsson, F., Ahl, J., Savidge, T. C., Dann-Grice, S. & Resman, F., Jan 1 2017, In : PLoS One. 12, 1, e0169386.

Research output: Contribution to journalArticle

1 Scopus citations
2016

MTOR mediates IL-23 induction of neutrophil IL-17 and IL-22 production

Chen, F., Cao, A., Yao, S., Evans-Marin, H. L., Liu, H., Wu, W., Carlsen, E. D., Dann-Grice, S., Soong, L., Sun, J., Zhao, Q. & Cong, Y., May 15 2016, In : Journal of Immunology. 196, 10, p. 4390-4399 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

New role for FDA-approved drugs in combating antibiotic-resistant bacteria

Andersson, J. A., Fitts, E. C., Kirtley, M. L., Ponnusamy, D., Peniche-Trujillo, A-G., Dann-Grice, S., Motin, V., Chauhan, S., Rosenzweig, J. A., Sha, J. & Chopra, A., Jun 1 2016, In : Antimicrobial Agents and Chemotherapy. 60, 6, p. 3717-3729 13 p.

Research output: Contribution to journalArticle

17 Scopus citations

Peptide nanofiber-CaCO3 composite microparticles as adjuvant-free oral vaccine delivery vehicles

Snook, J. D., Chesson, C. B., Peniche-Trujillo, A-G., Dann-Grice, S., Paulucci, A., Pinchuk, I. & Rudra, J. S., 2016, In : Journal of Materials Chemistry B. 4, 9, p. 1640-1649 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Regulation of protein-ligand binding affinity by hydrogen bond pairing

Chen, D., Oezguen, N., Urvil, P., Ferguson, C., Dann-Grice, S. & Savidge, T. C., Mar 1 2016, In : Science advances. 2, 3, p. e1501240

Research output: Contribution to journalArticle

63 Scopus citations
2015

IL-17A promotes protective IgA responses and expression of other potential effectors against the lumen-dwelling enteric parasite Giardia

Dann-Grice, S., Manthey, C. F., Le, C., Miyamoto, Y., Gima, L., Abrahim, A., Cao, A. T., Hanson, E. M., Kolls, J. K., Raz, E., Cong, Y. & Eckmann, L., Sep 1 2015, In : Experimental Parasitology. 156, p. 68-78 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

TGF-β converts Th1 cells into Th17 cells through stimulation of Runx1 expression

Liu, H. P., Cao, A. T., Feng, T., Li, Q., Zhang, W., Yao, S., Dann, S. M., Elson, C. O. & Cong, Y., Apr 1 2015, In : European Journal of Immunology. 45, 4, p. 1010-1018 9 p.

Research output: Contribution to journalArticle

49 Scopus citations

Unexpected regulatory role of CCR9 in regulatory T cell development

Evans-Marin, H. L., Cao, A. T., Yao, S., Chen, F., He, C., Liu, H., Wu, W., Gonzalez, M. G., Dann-Grice, S. & Cong, Y., Jul 31 2015, In : PLoS One. 10, 7, e0134100.

Research output: Contribution to journalArticle

16 Scopus citations
2014

Attenuation of intestinal inflammation in interleukin-10-deficient mice infected with Citrobacter rodentium

Dann, S. M., Le, C., Choudhury, B. K., Liu, H., Saldarriaga, O., Hanson, E. M., Cong, Y. & Eckmann, L., May 2014, In : Infection and immunity. 82, 5, p. 1949-1958 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

TLR4 activation enhances the PD-L1-mediated tolerogenic capacity of colonic CD90+stromal cells

Beswick, E. J., Johnson, J. R., Saada, J. I., Humen, M., House, J., Dann, S., Qiu, S., Brasier, A. R., Powell, D. W., Reyes, V. E. & Pinchuk, I. V., Sep 1 2014, In : Journal of Immunology. 193, 5, p. 2218-2229 12 p.

Research output: Contribution to journalArticle

36 Scopus citations
2013

A novel calcium-dependent protein kinase inhibitor as a lead compound for treating cryptosporidiosis

Castellanos-Gonzalez, A., White, A. C., Ojo, K. K., Vidadala, R. S. R., Zhang, Z., Reid, M. C., Fox, A. M. W., Keyloun, K. R., Rivas, K., Irani, A., Dann, S. M., Fan, E., Maly, D. J. & Van Voorhis, W. C., Oct 15 2013, In : Journal of Infectious Diseases. 208, 8, p. 1342-1348 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Community-Acquired Clostridium Difficile Infection: Awareness and Clinical Implications

Juneau, C., Mendias, E. N. P., Wagal, N., Loeffelholz, M., Savidge, T., Croisant, S. & Dann, S. M., Jan 2013, In : Journal for Nurse Practitioners. 9, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

ERK differentially regulates Th17- and Treg-cell development and contributes to the pathogenesis of colitis

Liu, H., Yao, S., Dann, S. M., Qin, H., Elson, C. O. & Cong, Y., Jul 1 2013, In : European Journal of Immunology. 43, 7, p. 1716-1726 11 p.

Research output: Contribution to journalArticle

49 Scopus citations

Recent insights into Clostridium difficile pathogenesis

Peniche, A. G., Savidge, T. C. & Dann, S. M., Oct 1 2013, In : Current opinion in infectious diseases. 26, 5, p. 447-453 7 p.

Research output: Contribution to journalReview article

34 Scopus citations

Trp53 deficiency protects against acute intestinal inflammation

Spehlmann, M. E., Manthey, C. F., Dann, S. M., Hanson, E., Sandhu, S. S., Liu, L. Y., Abdelmalak, F. K., Diamanti, M. A., Retzlaff, K., Scheller, J., Rose-John, S., Greten, F. R., Wang, J. Y. J. & Eckmann, L., Jul 15 2013, In : Journal of Immunology. 191, 2, p. 837-847 11 p.

Research output: Contribution to journalArticle

25 Scopus citations
2012

Divergent requirement for Gαs and cAMP in the differentiation and inflammatory profile of distinct mouse Th subsets

Li, X., Murray, F., Koide, N., Goldstone, J., Dann, S. M., Chen, J., Bertin, S., Fu, G., Weinstein, L. S., Chen, M., Corr, M., Eckmann, L., Insel, P. A. & Raz, E., Mar 1 2012, In : Journal of Clinical Investigation. 122, 3, p. 963-973 11 p.

Research output: Contribution to journalArticle

33 Scopus citations
2010

GM-CSF-Facilitated Dendritic Cell Recruitment and Survival Govern the Intestinal Mucosal Response to a Mouse Enteric Bacterial Pathogen

Hirata, Y., Egea, L., Dann, S. M., Eckmann, L. & Kagnoff, M. F., Feb 18 2010, In : Cell Host and Microbe. 7, 2, p. 151-163 13 p.

Research output: Contribution to journalArticle

40 Scopus citations

Human CD8+ T cells clear Cryptosporidium parvum from infected intestinal epithelial cells

Pantenburg, B., Castellanos-Gonzalez, A., Dann, S. M., Connelly, R. L., Lewis, D. E., Ward, H. D. & White, A. C., Apr 1 2010, In : American Journal of Tropical Medicine and Hygiene. 82, 4, p. 600-607 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

STAT3 and its activators in intestinal defense and mucosal homeostasis

Hruz, P., Dann, S. M. & Eckmann, L., Mar 1 2010, In : Current Opinion in Gastroenterology. 26, 2, p. 109-115 7 p.

Research output: Contribution to journalReview article

31 Scopus citations
2009

CXCR2-dependent mucosal neutrophil influx protects against colitis-associated diarrhea caused by an attaching/effacing lesion-forming bacterial pathogen

Spehlmann, M. E., Dann, S. M., Hruz, P., Hanson, E., McCole, D. F. & Eckmann, L., Sep 1 2009, In : Journal of Immunology. 183, 5, p. 3332-3343 12 p.

Research output: Contribution to journalArticle

67 Scopus citations
2008

IL-6-dependent mucosal protection prevents establishment of a microbial niche for attaching/effacing lesion-forming enteric bacterial pathogens

Dann, S. M., Spehlmann, M. E., Hammond, D. C., Iimura, M., Hase, K., Choi, L. J., Hanson, E. & Eckmann, L., Jan 1 2008, In : Journal of Immunology. 180, 10, p. 6816-6826 11 p.

Research output: Contribution to journalArticle

Open Access
109 Scopus citations

Intestinal immune response to human Cryptosporidium sp. infection

Pantenburg, B., Dann, S. M., Wang, H. C., Robinson, P., Castellanos-Gonzalez, A., Lewis, D. E. & White, A. C., Jan 1 2008, In : Infection and immunity. 76, 1, p. 23-29 7 p.

Research output: Contribution to journalShort survey

39 Scopus citations

Opposing functions of IKKβ during acute and chronic intestinal inflammation

Eckmann, L., Nebelsiek, T., Fingerle, A. A., Dann, S. M., Mages, J., Lang, R., Robine, S., Kagnoff, M. F., Schmid, R. M., Karin, M., Arkan, M. C. & Greten, F. R., Sep 30 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 39, p. 15058-15063 6 p.

Research output: Contribution to journalArticle

119 Scopus citations
2007

High levels of CXCL10 are produced by intestinal epithelial cells in AIDS patients with active cryptosporidiosis but not after reconstitution of immunity

Wang, H. C., Dann, S. M., Okhuysen, P. C., Lewis, D. E., Chappell, C. L., Adler, D. G. & White, A. C., Jan 1 2007, In : Infection and immunity. 75, 1, p. 481-487 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Innate immune defenses in the intestinal tract

Dann, S. M. & Eckmann, L., Mar 1 2007, In : Current Opinion in Gastroenterology. 23, 2, p. 115-120 6 p.

Research output: Contribution to journalReview article

70 Scopus citations
2005

Interleukin-15 activates human natural killer cells to clear the intestinal protozoan Cryptosporidium

Dann, S. M., Wang, H. C., Gambarin, K. J., Actor, J. K., Robinson, P., Lewis, D. E., Caillat-Zucman, S. & White, A. C., Sep 1 2005, In : Journal of Infectious Diseases. 192, 7, p. 1294-1302 9 p.

Research output: Contribution to journalArticle

45 Scopus citations
2001

Serological responses to Cryptosporidium infection [1] (multiple letters)

Muller, T. B., Frost, F. J., Craun, G. F., Calderon, R. L., Chappell, C. L., Okhuysen, P. C. & Dann, S. M., Mar 14 2001, In : Infection and immunity. 69, 3, p. 1974-1975 2 p.

Research output: Contribution to journalLetter

16 Scopus citations
2000

Fecal antibodies to Cryptosporidium parvum in healthy volunteers

Dann, S. M., Okhuysen, P. C., Salameh, B. M., DuPont, H. L. & Chappell, C. L., Sep 14 2000, In : Infection and immunity. 68, 9, p. 5068-5074 7 p.

Research output: Contribution to journalArticle

16 Scopus citations