• 21994 Citations
  • 86 h-Index
1973 …2022

Research output per year

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Research Output

1998

Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites

Johnson, R. E., Torres-Ramos, C. A., Izumi, T., Mitra, S., Prakash, S. & Prakash, L., Oct 1 1998, In : Genes and Development. 12, 19, p. 3137-3143 7 p.

Research output: Contribution to journalArticle

Open Access
166 Scopus citations

Role of yeast Rth1 nuclease and its homologs in mutation avoidance, DNA repair, and DNA replication

Johnson, R. E., Kovvali, G. K., Prakash, L. & Prakash, S., Jul 1 1998, In : Current Genetics. 34, 1, p. 21-29 9 p.

Research output: Contribution to journalArticle

49 Scopus citations

The DNA-dependent atpase activity of yeast nucleotide excision repair factor 4 and its role in DNA damage recognition

Guzder, S. N., Sung, P., Prakash, L. & Prakash, S., Mar 13 1998, In : Journal of Biological Chemistry. 273, 11, p. 6292-6296 5 p.

Research output: Contribution to journalArticle

42 Scopus citations
1997

Domains required for dimerization of yeast Rad6 ubiquitin-conjugating enzyme and Rad18 DNA binding protein

Bailly, V., Prakash, S. & Prakash, L., Aug 1997, In : Molecular and Cellular Biology. 17, 8, p. 4536-4543 8 p.

Research output: Contribution to journalArticle

Open Access
89 Scopus citations

Enhancement of MSH2-MSH3-mediated mismatch recognition by the yeast MLH1-PMS1 complex

Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Oct 1 1997, In : Current Biology. 7, 10, p. 790-793 4 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations

Requirement of yeast DNA polymerase δ in post-replicational repair of UV-damaged DNA

Torres-Ramos, C. A., Prakash, S. & Prakash, L., Oct 10 1997, In : Journal of Biological Chemistry. 272, 41, p. 25445-25448 4 p.

Research output: Contribution to journalArticle

39 Scopus citations

Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities

Bailly, V., Lauder, S., Prakash, S. & Prakash, L., Sep 26 1997, In : Journal of Biological Chemistry. 272, 37, p. 23360-23365 6 p.

Research output: Contribution to journalArticle

231 Scopus citations
67 Scopus citations
1996

An affinity of human replication protein A for ultraviolet-damaged DNA: Implications for damage recognition in nucleotide excision repair

Burns, J. L., Guzder, S. N., Sung, P., Prakash, S. & Prakash, L., Jan 1 1996, In : Journal of Biological Chemistry. 271, 20, p. 11607-11610 4 p.

Research output: Contribution to journalArticle

Open Access
108 Scopus citations

Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3

Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Sep 1996, In : Current Biology. 6, 9, p. 1185-1187 3 p.

Research output: Contribution to journalArticle

109 Scopus citations

Dual requirement for the yeast MMS19 gene in DNA repair and RNA polymerase II transcription

Lauder, S., Bankmann, M., Guzder, S. N., Sung, P., Prakash, L. & Prakash, S., Jan 1 1996, In : Molecular and Cellular Biology. 16, 12, p. 6783-6793 11 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations

Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair

Johnson, R. E., Kovvali, G. K., Guzder, S. N., Amin, N. S., Holm, C., Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Nov 19 1996, In : Journal of Biological Chemistry. 271, 45, p. 27987-27990 4 p.

Research output: Contribution to journalArticle

167 Scopus citations

Nucleotide excision repair in yeast is mediated by sequential assembly of repair factors and not by a pre-assembled repairosome

Guzder, S. N., Sung, P., Prakash, L. & Prakash, S., Apr 12 1996, In : Journal of Biological Chemistry. 271, 15, p. 8903-8910 8 p.

Research output: Contribution to journalArticle

72 Scopus citations

RAD26, the yeast homolog of human Cockayne's syndrome group B gene, encodes a DNA-dependent ATPase

Guzder, S. N., Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Oct 7 1996, In : Journal of Biological Chemistry. 271, 31, p. 18314-18317 4 p.

Research output: Contribution to journalArticle

59 Scopus citations

Reconstitution of TFIIH and requirement of its DNA helicase subunits, Rad3 and Rad25, in the incision step of nucleotide excision repair

Sung, P., Guzder, S. N., Prakash, L. & Prakash, S., May 20 1996, In : Journal of Biological Chemistry. 271, 18, p. 10821-10826 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

Requirement of mismatch repair genes MSH2 and MSH3 in the RAD1-RAD10 pathway of mitotic recombination in Saccharomyces cerevisiae

Saparbaev, M., Prakash, L. & Prakash, S., Mar 1 1996, In : Genetics. 142, 3, p. 727-736 10 p.

Research output: Contribution to journalArticle

112 Scopus citations

Requirement of proliferating cell nuclear antigen in RAD6-dependent postreplicational DNA repair

Torres-Ramos, C. A., Yoder, B. L., Burgers, P. M. J., Prakash, S. & Prakash, L., Sep 3 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 18, p. 9676-9681 6 p.

Research output: Contribution to journalArticle

94 Scopus citations

Requirement of the yeast MSH3 and MSH6 genes for MSH2-dependent genomic stability

Johnson, R. E., Kovvali, G. K., Prakash, L. & Prakash, S., Mar 29 1996, In : Journal of Biological Chemistry. 271, 13, p. 7285-7288 4 p.

Research output: Contribution to journalArticle

164 Scopus citations
42 Scopus citations
1995
Open Access
162 Scopus citations
Open Access
23 Scopus citations

Reconstitution of yeast nucleotide excision repair with purified Rad proteins, replication protein A, and transcription factor TFIIH

Guzder, S. N., Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Jan 1 1995, In : Journal of Biological Chemistry. 270, 22, p. 12973-12976 4 p.

Research output: Contribution to journalArticle

187 Scopus citations

Requirement of the yeast RTH1 5′ to 3′ exonuclease for the stability of simple repetitive DNA

Johnson, R. E., Kovvali, G. K., Prakash, L. & Prakash, S., Jan 1 1995, In : Science. 269, 5221, p. 238-240 3 p.

Research output: Contribution to journalArticle

191 Scopus citations

Structure-specific nuclease activity in yeast nucleotide excision repair protein Rad2

Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Dec 15 1995, In : Journal of Biological Chemistry. 270, 50, p. 30194-30198 5 p.

Research output: Contribution to journalArticle

47 Scopus citations

Yeast DNA repair protein RAD23 promotes complex formation between transcription factor TFIIH and DNA damage recognition factor RAD14

Guzder, S. N., Bailly, V., Sung, P., Prakash, L. & Prakash, S., Jan 1 1995, In : Journal of Biological Chemistry. 270, 15, p. 8385-8388 4 p.

Research output: Contribution to journalArticle

67 Scopus citations
1994

A conserved 5' to 3' exonuclease activity in the yeast and human nucleotide excision repair proteins RAD2 and XPG

Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Jan 1 1994, In : Journal of Biological Chemistry. 269, 50, p. 31342-31345 4 p.

Research output: Contribution to journalArticle

50 Scopus citations

DNA repair gene RAD3 of S. cerevisiae is essential for transcription by RNA polymerase II

Guzder, S. N., Qiu, H., Sommers, C. H., Sung, P., Prakash, L. & Prakash, S., Jan 1 1994, In : Nature. 367, 6458, p. 91-94 4 p.

Research output: Contribution to journalArticle

118 Scopus citations

Holliday junction cleavage by yeast Rad1 protein

Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Jan 1 1994, In : Nature. 371, 6497, p. 531-534 4 p.

Research output: Contribution to journalArticle

39 Scopus citations

Human xeroderma pigmentosum group G gene encodes a DNA endonuclease

Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Aug 25 1994, In : Nucleic acids research. 22, 16, p. 3312-3316 5 p.

Research output: Contribution to journalArticle

31 Scopus citations

Negative superhelicity promotes ATP-dependent binding of yeast RAD3 protein to ultraviolet-damaged DNA

Sung, P., Watkins, J. F., Prakash, L. & Prakash, S., Mar 18 1994, In : Journal of Biological Chemistry. 269, 11, p. 8303-8308 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

RAD25 is a DMA helicase required for DNA repair and RNA polymerase II transcription

Guzder, S. N., Sung, P., Bailly, V., Prakash, L. & Prakash, S., Jan 1 1994, In : Nature. 369, 6481, p. 578-581 4 p.

Research output: Contribution to journalArticle

147 Scopus citations
Open Access
255 Scopus citations

Yeast DNA repair protein RAD5 that promotes instability of simple repetitive sequences is a DNA-dependent ATPase

Johnson, R. E., Prakash, S. & Prakash, L., Nov 11 1994, In : Journal of Biological Chemistry. 269, 45, p. 28259-28262 4 p.

Research output: Contribution to journalArticle

82 Scopus citations
1993

DNA repair genes and proteins of Saccharomyces cerevisiae

Prakash, S., Sung, P. & Prakash, L., Jan 1 1993, In : Annual Review of Genetics. 27, p. 33-70 38 p.

Research output: Contribution to journalReview article

245 Scopus citations

Human xeroderma pigmentosum group D gene encodes a DNA helicase

Sung, P., Bailly, V., Weber, C., Thompson, L. H., Prakash, L. & Prakash, S., Jan 1 1993, In : Nature. 365, 6449, p. 852-855 4 p.

Research output: Contribution to journalArticle

270 Scopus citations

Purification and characterization of the Saccharomyces cerevisiae RAD1/RAD10 endonuclease

Sung, P., Reynolds, P., Prakash, L. & Prakash, S., Jan 1 1993, In : Journal of Biological Chemistry. 268, 35, p. 26391-26399 9 p.

Research output: Contribution to journalArticle

92 Scopus citations

The extremely conserved amino terminus of RAD6 ubiquitin-conjugating enzyme is essential for amino-end rule-dependent protein degradation

Watkins, J. F., Sung, P., Prakash, S. & Prakash, L., Jan 1 1993, In : Genes and Development. 7, 2, p. 250-261 12 p.

Research output: Contribution to journalArticle

Open Access
71 Scopus citations
Open Access
201 Scopus citations

The Saccharomyces cerevisiae DNA repair gene RAD25 is required for transcription by RNA polymerase II

Qiu, H., Park, E., Prakash, L. & Prakash, S., Jan 1 1993, In : Genes and Development. 7, 11, p. 2161-2171 11 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations
Open Access
86 Scopus citations

Yeast excision repair gene RAD2 encodes a single-stranded DNA endonuclease

Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Jan 1 1993, In : Nature. 366, 6453, p. 365-368 4 p.

Research output: Contribution to journalArticle

111 Scopus citations
1992

RAD25 (SSL2), the yeast homolog of the human xeroderma pigmentosum group B DNA repair gene, is essential for viability

Park, E., Guzder, S. N., Koken, M. H. M., Jaspers-Dekker, I., Weeda, G., Hoeijmakers, J. H. J., Prakash, S. & Prakash, L., Dec 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 23, p. 11416-11420 5 p.

Research output: Contribution to journalArticle

Open Access
103 Scopus citations

Renaturation of DNA catalysed by yeast DNA repair and recombination protein RAD10

Sung, P., Prakash, L. & Prakash, S., Jan 1 1992, In : Nature. 355, 6362, p. 743-745 3 p.

Research output: Contribution to journalArticle

33 Scopus citations

Saccharomyces cerevisiae RAD5-encoded DNA repair protein contains DNA helicase and zinc-binding sequence motifs and affects the stability of simple repetitive sequences in the genome

Johnson, R. E., Henderson, S. T., Petes, T. D., Prakash, S., Bankmann, M. & Prakash, L., Jan 1 1992, In : Molecular and cellular biology. 12, 9, p. 3807-3818 12 p.

Research output: Contribution to journalArticle

Open Access
180 Scopus citations
Open Access
55 Scopus citations
21 Scopus citations

YeastRAD14 and human xeroderma pigmentosum group A DNA-repair genes encode homologous proteins

Bankmann, M., Prakash, L. & Prakash, S., Jan 1 1992, In : Nature. 355, 6360, p. 555-558 4 p.

Research output: Contribution to journalArticle

94 Scopus citations
1991

Dhr6, a Drosophila homolog of the yeast DNA-repair gene RAD6

Koken, M., Reynolds, P., Bootsma, D., Hoeijmakers, J., Prakash, S. & Prakash, L., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 9, p. 3832-3836 5 p.

Research output: Contribution to journalArticle

68 Scopus citations

DNA-RNA helicase activity of RAD3 protein of Saccharomyces cerevisiae

Bailly, V., Sung, P., Prakash, L. & Prakash, S., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 21, p. 9712-9716 5 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations
51 Scopus citations