• 21994 Citations
  • 86 h-Index
1973 …2022

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Article
52 Scopus citations

a/α-Specific effect of the mms3 mutation on ultraviolet mutagenesis in Saccharomyces cerevisiae

Martin, P., Prakash, L. & Prakash, S., Jan 1 1981, In : Journal of bacteriology. 146, 2, p. 684-691 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Accuracy of lesion bypass by yeast and human DNA polymerase η

Washington, M. T., Johnson, R. E., Prakash, L. & Prakash, S., Jul 17 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 15, p. 8355-8360 6 p.

Research output: Contribution to journalArticle

62 Scopus citations

Accuracy of thymine-thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase η

Washington, M. T., Johnson, R. E., Prakash, S. & Prakash, L., Mar 28 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 7, p. 3094-3099 6 p.

Research output: Contribution to journalArticle

163 Scopus citations

Acidic residues critical for the activity and biological function of yeast DNA polymerase η

Kondratick, C. M., Washington, M. T., Prakash, S. & Prakash, L., Mar 1 2001, In : Molecular and Cellular Biology. 21, 6, p. 2018-2025 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

A comparative study of the esterase 5 locus in Drosophila pseudoobscura, D. persimilis and D. miranda

Cobbs, G. & Prakash, S., Dec 1 1977, In : Genetics. 85, 4, p. 697-711 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

A conserved 5' to 3' exonuclease activity in the yeast and human nucleotide excision repair proteins RAD2 and XPG

Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Jan 1 1994, In : Journal of Biological Chemistry. 269, 50, p. 31342-31345 4 p.

Research output: Contribution to journalArticle

50 Scopus citations

Activity variants of acid phosphatase-3 among chromosome 3 inversions of Drosophila pseudoobscura

Norman, R. A. & Prakash, S., Dec 1 1980, In : Genetics. 96, 3, p. 743-755 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Affinity of yeast nucleotide excision repair factor 2, consisting of the Rad4 and Rad23 proteins, for ultraviolet damaged DNA

Guzder, S. N., Sung, P., Prakash, L. & Prakash, S., Nov 20 1998, In : Journal of Biological Chemistry. 273, 47, p. 31541-31546 6 p.

Research output: Contribution to journalArticle

88 Scopus citations
Open Access
10 Scopus citations

Allelic variants at the xanthine dehydrogenase locus affecting enzyme activity in Drosophila pseudoobscura

Prakash, S., Jan 1 1977, In : Genetics. 87, 1, p. 159-168 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands

Johnson, R. E., Klassen, R., Prakash, L. & Prakash, S., Jul 16 2015, In : Molecular Cell. 59, 2, p. 163-175 13 p.

Research output: Contribution to journalArticle

114 Scopus citations

A mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repair

Haracska, L., Prakash, L. & Prakash, S., Nov 15 2003, In : Genes and Development. 17, 22, p. 2777-2785 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

An affinity of human replication protein A for ultraviolet-damaged DNA: Implications for damage recognition in nucleotide excision repair

Burns, J. L., Guzder, S. N., Sung, P., Prakash, S. & Prakash, L., Jan 1 1996, In : Journal of Biological Chemistry. 271, 20, p. 11607-11610 4 p.

Research output: Contribution to journalArticle

Open Access
108 Scopus citations
9 Scopus citations

An Incoming Nucleotide Imposes an anti to syn Conformational Change on the Templating Purine in the Human DNA Polymerase-ι Active Site

Nair, D. T., Johnson, R. E., Prakash, L., Prakash, S. & Aggarwal, A. K., Apr 1 2006, In : Structure. 14, 4, p. 749-755 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε

Jain, R., Vanamee, E. S., Dzikovski, B. G., Buku, A., Johnson, R. E., Prakash, L., Prakash, S. & Aggarwal, A. K., Jan 23 2014, In : Journal of Molecular Biology. 426, 2, p. 301-308 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Apurinic endonuclease activity of yeast Apn2 protein

Unk, I., Haracska, L., Johnson, R. E., Prakash, S. & Prakash, L., Jul 21 2000, In : Journal of Biological Chemistry. 275, 29, p. 22427-22434 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

A role for DNA polymerase θ in promoting replication through oxidative DNA lesion, thymine glycol, in human cells

Yoon, J. H., Choudhury, J. R., Park, J., Prakash, S. & Prakash, L., Jan 1 2014, In : Journal of Biological Chemistry. 289, 19, p. 13177-13185 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

A role for yeast and human translesion synthesis DNA polymerases in promoting replication through 3-methyl adenine

Johnson, R. E., Yu, S. L., Prakash, S. & Prakash, L., Oct 1 2007, In : Molecular and cellular biology. 27, 20, p. 7198-7205 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

A single domain in human DNA polymerase ι mediates interaction with PCNA: Implications for translesion DNA synthesis

Haracska, L., Acharya, N., Unk, I., Johnson, R. E., Hurwitz, J., Prakash, L. & Prakash, S., Feb 1 2005, In : Molecular and cellular biology. 25, 3, p. 1183-1190 8 p.

Research output: Contribution to journalArticle

41 Scopus citations

Association of alleles of the malic dehydrogenase locus with a pericentric inversion in Drosophila robusta

Prakash, S. & Levitan, M., Dec 1 1974, In : Genetics. 77, 3, p. 565-568 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Associations of alleles of the esterase 1 locus with gene arrangements of the left arm of the second chromosome in Drosophila robusta

Prakash, S. & Levitan, M., Dec 1 1973, In : Genetics. 75, 2, p. 371-379 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

ATP-dependent assembly of a ternary complex consisting of a DNA mismatch and the yeast MSH2-MSH6 and MLH1-PMS1 protein complexes

Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Apr 17 1998, In : Journal of Biological Chemistry. 273, 16, p. 9837-9841 5 p.

Research output: Contribution to journalArticle

103 Scopus citations

Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3

Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Sep 1996, In : Current Biology. 6, 9, p. 1185-1187 3 p.

Research output: Contribution to journalArticle

109 Scopus citations
51 Scopus citations

Biochemistry: Rev1 employs a novel mechanism of DNA synthesis using a protein template

Nair, D. T., Johnson, R. E., Prakash, L., Prakash, S. & Aggarwal, A. K., Sep 30 2005, In : Science. 309, 5744, p. 2219-2222 4 p.

Research output: Contribution to journalArticle

178 Scopus citations

Cloning and nucleotide sequence analysis of the Saccharomyces cerevisiae RAD4 gene required for excision repair of UV-damaged DNA

Gietz, R. D. & Prakash, S., Dec 30 1988, In : Gene. 74, 2, p. 535-541 7 p.

Research output: Contribution to journalArticle

26 Scopus citations
103 Scopus citations

Complex formation of yeast Rev1 and Rev7 proteins: A novel role for the polymerase-associated domain

Acharya, N., Haracska, L., Johnson, R. E., Unk, I., Prakash, S. & Prakash, L., Nov 1 2005, In : Molecular and cellular biology. 25, 21, p. 9734-9740 7 p.

Research output: Contribution to journalArticle

60 Scopus citations

Complex formation of yeast Rev1 with DNA polymerase η

Acharya, N., Haracska, L., Prakash, S. & Prakash, L., Dec 1 2007, In : Molecular and cellular biology. 27, 23, p. 8401-8408 8 p.

Research output: Contribution to journalArticle

39 Scopus citations
32 Scopus citations
95 Scopus citations
Open Access
162 Scopus citations

Conserved pattern of antisense overlapping transcription in the homologous human ERCC-1 and yeast RAD10 DNA repair gene regions

Van Duin, M., Van den Tol, J., Hoeijmakers, J. H. J., Bootsma, D., Rupp, I. P., Reynolds, P., Prakash, L. & Prakash, S., Jan 1 1989, In : Molecular and Cellular Biology. 9, 4, p. 1794-1798 5 p.

Research output: Contribution to journalArticle

Open Access
38 Scopus citations

Cryo-EM structure and dynamics of eukaryotic DNA polymerase δ holoenzyme

Jain, R., Rice, W. J., Malik, R., Johnson, R. E., Prakash, L., Prakash, S., Ubarretxena-Belandia, I. & Aggarwal, A. K., Oct 1 2019, In : Nature Structural and Molecular Biology. 26, 10, p. 955-962 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Crystal structure of the catalytic core of human DNA polymerase kappa

Uljon, S. N., Johnson, R. E., Edwards, T. A., Prakash, S., Prakash, L. & Aggarwal, A. K., Aug 1 2004, In : Structure. 12, 8, p. 1395-1404 10 p.

Research output: Contribution to journalArticle

84 Scopus citations

Crystal structure of the Saccharomyces cerevisiae ubiquitin-conjugating enzyme Rad6 at 2.6 Å resolution

Worthylake, D. K., Prakash, S., Prakash, L. & Hill, C. P., Mar 13 1998, In : Journal of Biological Chemistry. 273, 11, p. 6271-6276 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Crystal structure of yeast DNA polymerase ε catalytic domain

Jain, R., Rajashankar, K. R., Buku, A., Johnson, R. E., Prakash, L., Prakash, S. & Aggarwal, A. K., Apr 14 2014, In : PloS one. 9, 4, e94835.

Research output: Contribution to journalArticle

21 Scopus citations

Decreased UV mutagenesis in cdc8, a DNA replication mutant of Saccharomyces cerevisiae

Prakash, L., Hinkle, D. & Prakash, S., Jan 1 1979, In : MGG Molecular & General Genetics. 172, 3, p. 249-258 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
47 Scopus citations

Deoxynucleotide triphosphate binding mode conserved in Y family DNA polymerases

Johnson, R. E., Trincao, J., Aggarwal, A. K., Prakash, S. & Prakash, L., Apr 1 2003, In : Molecular and Cellular Biology. 23, 8, p. 3008-3012 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Developmental variation in amylase allozyme activity associated with chromosome inversions in Drosophila persimilis

Norman, R. A. & Prakash, S., Dec 1 1980, In : Genetics. 95, 4, p. 1001-1011 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Dhr6, a Drosophila homolog of the yeast DNA-repair gene RAD6

Koken, M., Reynolds, P., Bootsma, D., Hoeijmakers, J., Prakash, S. & Prakash, L., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 9, p. 3832-3836 5 p.

Research output: Contribution to journalArticle

68 Scopus citations
11 Scopus citations

Distinction among allelic variants associated with chromosome 3 inversions in Drosophila pseudoobscura and Drosophila persimilis

Norman, R. A. & Prakash, S., Jan 1 1980, In : Genetics. 96, 3, p. 727-741 15 p.

Research output: Contribution to journalArticle

2 Scopus citations
27 Scopus citations

DNA polymerases: Hoogsteen base-pairing in DNA replication? (reply)

Aggarwal, A., Nair, D., Johnson, R., Prakash, L. & Prakash, S., Sep 14 2005, In : Nature. 437, 7057, p. E7

Research output: Contribution to journalArticle

2 Scopus citations

DNA polymerase θ accomplishes translesion synthesis opposite 1, N 6 -ethenodeoxyadenosine with a remarkably high fidelity in human cells

Yoon, J. H., Johnson, R. E., Prakash, L. & Prakash, S., Mar 1 2019, In : Genes and Development. 33, 5-6, p. 282-287 6 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

DNA repair gene RAD3 of S. cerevisiae is essential for transcription by RNA polymerase II

Guzder, S. N., Qiu, H., Sommers, C. H., Sung, P., Prakash, L. & Prakash, S., Jan 1 1994, In : Nature. 367, 6458, p. 91-94 4 p.

Research output: Contribution to journalArticle

118 Scopus citations