• 21994 Citations
  • 86 h-Index
1973 …2022

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2002

Requirement of yeast RAD2, a homolog of human XPG gene, for efficient RNA polymerase II transcription: Implications for Cockayne syndrome

Lee, S. K., Yu, S. L., Prakash, L. & Prakash, S., Jun 28 2002, In : Cell. 109, 7, p. 823-834 12 p.

Research output: Contribution to journalArticle

73 Scopus citations

Role of human DNA polymerase κ as an extender in translesion synthesis

Haracska, L., Prakash, L. & Prakash, S., Dec 10 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 25, p. 16000-16005 6 p.

Research output: Contribution to journalArticle

123 Scopus citations

Stimulation of 3′→5′ exonuclease and 3′-phosphodiesterase activities of yeast Apn2 by proliferating cell nuclear antigen

Unk, I., Haracska, L., Gomes, X. V., Burgers, P. M. J., Prakash, L. & Prakash, S., Sep 1 2002, In : Molecular and cellular biology. 22, 18, p. 6480-6486 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Stimulation of DNA synthesis activity of human DNA polymerase κ by PCNA

Haracska, L., Unk, I., Johnson, R. E., Phillips, B. B., Hurwitz, J., Prakash, L. & Prakash, S., Jan 1 2002, In : Molecular and cellular biology. 22, 3, p. 784-791 8 p.

Research output: Contribution to journalArticle

Open Access
145 Scopus citations
39 Scopus citations

Yeast Rev1 protein is a G template-specific DNA polymerase

Haracska, L., Prakash, S. & Prakash, L., May 3 2002, In : Journal of Biological Chemistry. 277, 18, p. 15546-15551 6 p.

Research output: Contribution to journalArticle

124 Scopus citations
2001
52 Scopus citations

Accuracy of lesion bypass by yeast and human DNA polymerase η

Washington, M. T., Johnson, R. E., Prakash, L. & Prakash, S., Jul 17 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 15, p. 8355-8360 6 p.

Research output: Contribution to journalArticle

62 Scopus citations

Acidic residues critical for the activity and biological function of yeast DNA polymerase η

Kondratick, C. M., Washington, M. T., Prakash, S. & Prakash, L., Mar 1 2001, In : Molecular and Cellular Biology. 21, 6, p. 2018-2025 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

Fidelity and Damage Bypass Ability of Schizosaccharomyces pombe Eso1 Protein, Comprised of DNA Polymerase ηand Sister Chromatid Cohesion Protein Ctf7

Madril, A. C., Johnson, R. E., Washington, M. T., Prakash, L. & Prakash, S., Nov 16 2001, In : Journal of Biological Chemistry. 276, 46, p. 42857-42862 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Inefficient Bypass of an Abasic Site by DNA Polymerase η

Haracska, L., Washington, M. T., Prakash, S. & Prakash, L., Mar 2 2001, In : Journal of Biological Chemistry. 276, 9, p. 6861-6866 6 p.

Research output: Contribution to journalArticle

86 Scopus citations

Interaction with PCNA is essential for yeast DNA polymerase η function

Haracska, L., Kondratick, C. M., Unk, I., Prakash, S. & Prakash, L., Jan 1 2001, In : Molecular cell. 8, 2, p. 407-415 9 p.

Research output: Contribution to journalArticle

164 Scopus citations

Mismatch extension ability of yeast and human DNA polymerase η

Washington, M. T., Johnson, R. E., Prakash, S. & Prakash, L., Jan 19 2001, In : Journal of Biological Chemistry. 276, 3, p. 2263-2266 4 p.

Research output: Contribution to journalArticle

Open Access
42 Scopus citations

Physical and functional interactions of human DNA polymerase η with PCNA

Haracska, L., Johnson, R. E., Unk, I., Phillips, B., Hurwitz, J., Prakash, L. & Prakash, S., Oct 22 2001, In : Molecular and cellular biology. 21, 21, p. 7199-7206 8 p.

Research output: Contribution to journalArticle

195 Scopus citations

Requirement for yeast RAD26, a homolog of the human CSB gene, in elongation by RNA polymerase II

Lee, S. K., Yu, S. L., Prakash, L. & Prakash, S., Dec 13 2001, In : Molecular and Cellular Biology. 21, 24, p. 8651-8656 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

Requirement of DNA polymerase η for error-free bypass of UV-induced CC and TC photoproducts

Yu, S. L., Johnson, R. E., Prakash, S. & Prakash, L., Jan 1 2001, In : Molecular and cellular biology. 21, 1, p. 185-188 4 p.

Research output: Contribution to journalArticle

113 Scopus citations

Role of DNA polymerase η in the bypass of a (6-4) TT photoproduct

Johnson, R. E., Haracska, L., Prakash, S. & Prakash, L., May 9 2001, In : Molecular and cellular biology. 21, 10, p. 3558-3563 6 p.

Research output: Contribution to journalArticle

165 Scopus citations

Roles of yeast DNA polymerases δ and ζ of Rev 1 in the bypass of abasic sites

Haracska, L., Unk, I., Johnson, R. E., Johansson, E., Burgers, P. M. J., Prakash, S. & Prakash, L., Apr 15 2001, In : Genes and Development. 15, 8, p. 945-954 10 p.

Research output: Contribution to journalArticle

262 Scopus citations

Structure of the Catalytic Core of S. cerevisiae DNA polymerase η: Implications for translesion DNA synthesis

Trincao, J., Johnson, R. E., Escalante, C. R., Prakash, S., Prakash, L. & Aggarwal, A. K., Jan 1 2001, In : Molecular cell. 8, 2, p. 417-426 10 p.

Research output: Contribution to journalArticle

279 Scopus citations

Targeting of human DNA polymerase ι to the replication machinery via interaction with PCNA

Haracska, L., Johnson, R. E., Unk, I., Phillips, B. B., Hurwitz, J., Prakash, L. & Prakash, S., Dec 4 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 25, p. 14256-14261 6 p.

Research output: Contribution to journalArticle

166 Scopus citations

Translesion DNA Synthesis by Yeast DNA Polymerase η on Templates Containing N2-Guanine Adducts of 1,3-Butadiene Metabolites

Minko, I. G., Washington, M. T., Prakash, L., Prakash, S. & Lloyd, R. S., Jan 26 2001, In : Journal of Biological Chemistry. 276, 4, p. 2517-2522 6 p.

Research output: Contribution to journalArticle

34 Scopus citations

Yeast DNA polymerase η utilizes an induced-fit mechanism of nucleotide incorporation

Washington, M. T., Prakash, L. & Prakash, S., Dec 28 2001, In : Cell. 107, 7, p. 917-927 11 p.

Research output: Contribution to journalArticle

108 Scopus citations
2000

Accuracy of thymine-thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase η

Washington, M. T., Johnson, R. E., Prakash, S. & Prakash, L., Mar 28 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 7, p. 3094-3099 6 p.

Research output: Contribution to journalArticle

163 Scopus citations

Apurinic endonuclease activity of yeast Apn2 protein

Unk, I., Haracska, L., Johnson, R. E., Prakash, S. & Prakash, L., Jul 21 2000, In : Journal of Biological Chemistry. 275, 29, p. 22427-22434 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase η

Haracska, L., Yu, S. L., Johnson, R. E., Prakash, L. & Prakash, S., Dec 1 2000, In : Nature Genetics. 25, 4, p. 458-461 4 p.

Research output: Contribution to journalArticle

278 Scopus citations

Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, pol ηThe XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase ηhRAD30 mutations in the variant form of xeroderma pigmentosum

Johnson, R. E., Prakash, S., Prakash, L., Masutani, C., Kusumoto, R., Yamada, A., Dohmae, N., Yokoi, M., Yuasa, M., Araki, M., Iwoi, S., Tokio, K., Hanaoka, F., Johnson, R. E., Kondratick, C. M., Prakash, S. & Prakash, L., Dec 1 2000, In : Chemtracts. 13, 3, p. 203-210 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions

Johnson, R. E., Washington, M. T., Haracska, L., Prakash, S. & Prakash, L., Aug 31 2000, In : Nature. 406, 6799, p. 1015-1019 5 p.

Research output: Contribution to journalArticle

532 Scopus citations

Evidence for the involvement of nucleotide excision repair in the removal of abasic sites in yeast

Torres-Ramos, C. A., Johnson, R. E., Prakash, L. & Prakash, S., May 1 2000, In : Molecular and Cellular Biology. 20, 10, p. 3522-3528 7 p.

Research output: Contribution to journalArticle

61 Scopus citations

Fidelity of human DNA polymerase η

Johnson, R. E., Washington, M. T., Prakash, S. & Prakash, L., Mar 17 2000, In : Journal of Biological Chemistry. 275, 11, p. 7447-7450 4 p.

Research output: Contribution to journalArticle

344 Scopus citations

Replication past O6-Methylguanine by yeast and human DNA polymerase η

Haracska, L., Prakash, S. & Prakash, L., Jan 1 2000, In : Molecular and cellular biology. 20, 21, p. 8001-8007 7 p.

Research output: Contribution to journalArticle

111 Scopus citations

Role of yeast and human DNA polymerase η in error-free replication of damaged DNA

Prakash, S., Johnson, R. E., Washington, M. T., Haracska, L., Kondratick, C. M. & Prakash, L., Dec 1 2000, In : Cold Spring Harbor Symposia on Quantitative Biology. 65, p. 51-59 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

The human DINB1 gene encodes the DNA polymerase Polθ

Johnson, R. E., Prakash, S. & Prakash, L., Apr 11 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 8, p. 3838-3843 6 p.

Research output: Contribution to journalArticle

155 Scopus citations
1999

Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Polη

Johnson, R. E., Prakash, S. & Prakash, L., Feb 12 1999, In : Science. 283, 5404, p. 1001-1004 4 p.

Research output: Contribution to journalArticle

642 Scopus citations

Fidelity and processivity of Saccharomyces cerevisiae DNA polymerase η

Washington, M. T., Johnson, R. E., Prakash, S. & Prakash, L., Dec 24 1999, In : Journal of Biological Chemistry. 274, 52, p. 36835-36838 4 p.

Research output: Contribution to journalArticle

153 Scopus citations

hRAD30 mutations in the variant form of xeroderma pigmentosum

Johnson, R. E., Kondratick, C. M., Prakash, S. & Prakash, L., Jul 9 1999, In : Science. 285, 5425, p. 263-265 3 p.

Research output: Contribution to journalArticle

629 Scopus citations

Requirement of DNA polymerase activity of yeast Rad30 protein for its biological function

Johnson, R. E., Prakash, S. & Prakash, L., Jun 4 1999, In : Journal of Biological Chemistry. 274, 23, p. 15975-15977 3 p.

Research output: Contribution to journalArticle

103 Scopus citations

Requirement of yeast SGS1 and SRS2 genes for replication and transcription

Lee, S. K., Johnson, R. E., Yu, S. L., Prakash, L. & Prakash, S., Dec 17 1999, In : Science. 286, 5448, p. 2339-2342 4 p.

Research output: Contribution to journalArticle

121 Scopus citations

Synergistic interaction between yeast nucleotide excision repair factors NEF2 and NEF4 in the binding of ultraviolet-damaged DNA

Guzder, S. N., Sung, P., Prakash, L. & Prakash, S., Aug 20 1999, In : Journal of Biological Chemistry. 274, 34, p. 24257-24262 6 p.

Research output: Contribution to journalArticle

20 Scopus citations
1998

Affinity of yeast nucleotide excision repair factor 2, consisting of the Rad4 and Rad23 proteins, for ultraviolet damaged DNA

Guzder, S. N., Sung, P., Prakash, L. & Prakash, S., Nov 20 1998, In : Journal of Biological Chemistry. 273, 47, p. 31541-31546 6 p.

Research output: Contribution to journalArticle

88 Scopus citations

ATP-dependent assembly of a ternary complex consisting of a DNA mismatch and the yeast MSH2-MSH6 and MLH1-PMS1 protein complexes

Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Apr 17 1998, In : Journal of Biological Chemistry. 273, 16, p. 9837-9841 5 p.

Research output: Contribution to journalArticle

103 Scopus citations

Crystal structure of the Saccharomyces cerevisiae ubiquitin-conjugating enzyme Rad6 at 2.6 Å resolution

Worthylake, D. K., Prakash, S., Prakash, L. & Hill, C. P., Mar 13 1998, In : Journal of Biological Chemistry. 273, 11, p. 6271-6276 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites

Johnson, R. E., Torres-Ramos, C. A., Izumi, T., Mitra, S., Prakash, S. & Prakash, L., Oct 1 1998, In : Genes and Development. 12, 19, p. 3137-3143 7 p.

Research output: Contribution to journalArticle

Open Access
166 Scopus citations

Role of yeast Rth1 nuclease and its homologs in mutation avoidance, DNA repair, and DNA replication

Johnson, R. E., Kovvali, G. K., Prakash, L. & Prakash, S., Jul 1 1998, In : Current Genetics. 34, 1, p. 21-29 9 p.

Research output: Contribution to journalArticle

49 Scopus citations

The DNA-dependent atpase activity of yeast nucleotide excision repair factor 4 and its role in DNA damage recognition

Guzder, S. N., Sung, P., Prakash, L. & Prakash, S., Mar 13 1998, In : Journal of Biological Chemistry. 273, 11, p. 6292-6296 5 p.

Research output: Contribution to journalArticle

42 Scopus citations
1997

Domains required for dimerization of yeast Rad6 ubiquitin-conjugating enzyme and Rad18 DNA binding protein

Bailly, V., Prakash, S. & Prakash, L., Aug 1997, In : Molecular and Cellular Biology. 17, 8, p. 4536-4543 8 p.

Research output: Contribution to journalArticle

Open Access
89 Scopus citations

Enhancement of MSH2-MSH3-mediated mismatch recognition by the yeast MLH1-PMS1 complex

Habraken, Y., Sung, P., Prakash, L. & Prakash, S., Oct 1 1997, In : Current Biology. 7, 10, p. 790-793 4 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations

Requirement of yeast DNA polymerase δ in post-replicational repair of UV-damaged DNA

Torres-Ramos, C. A., Prakash, S. & Prakash, L., Oct 10 1997, In : Journal of Biological Chemistry. 272, 41, p. 25445-25448 4 p.

Research output: Contribution to journalArticle

39 Scopus citations

Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities

Bailly, V., Lauder, S., Prakash, S. & Prakash, L., Sep 26 1997, In : Journal of Biological Chemistry. 272, 37, p. 23360-23365 6 p.

Research output: Contribution to journalArticle

231 Scopus citations
67 Scopus citations
1996

An affinity of human replication protein A for ultraviolet-damaged DNA: Implications for damage recognition in nucleotide excision repair

Burns, J. L., Guzder, S. N., Sung, P., Prakash, S. & Prakash, L., Jan 1 1996, In : Journal of Biological Chemistry. 271, 20, p. 11607-11610 4 p.

Research output: Contribution to journalArticle

Open Access
108 Scopus citations