Scott Weaver, PhD, MS

Chair

  • 19926 Citations
  • 74 h-Index
1981 …2020

Research output per year

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Research Output

2018 international meeting of the Global Virus Network

Brechot, C., Bryant, J., Endtz, H., Garry, R. F., Griffin, D. E., Lewin, S. R., Mercer, N., Osterhaus, A., Picot, V., Vahlne, A., Verjans, G. M. G. M. & Weaver, S., Mar 2019, In : Antiviral research. 163, p. 140-148 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

4.4 Å cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus

Zhang, R., Hryc, C. F., Cong, Y., Liu, X., Jakana, J., Gorchakov, R., Baker, M. L., Weaver, S. C. & Chiu, W., Sep 2011, In : EMBO Journal. 30, 18, p. 3854-3863 10 p.

Research output: Contribution to journalArticle

119 Scopus citations

A cDNA Clone-Launched Platform for High-Yield Production of Inactivated Zika Vaccine

Yang, Y., Shan, C., Zou, J., Muruato, A. E., Bruno, D. N., de Almeida Medeiros Daniele, B., Vasconcelos, P. F. C., Rossi, S., Weaver, S., Xie, X. & Shi, P-Y., Jan 4 2017, (Accepted/In press) In : EBioMedicine.

Research output: Contribution to journalArticle

24 Scopus citations

A chikungunya fever vaccine utilizing an insect-specific virus platform

Erasmus, J. H., Auguste, A. J., Kaelber, J. T., Luo, H., Rossi, S. L., Fenton, K., Leal, G., Kim, D. Y., Chiu, W., Wang, T., Frolov, I., Nasar, F. & Weaver, S. C., Feb 1 2017, In : Nature Medicine. 23, 2, p. 192-199 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

A chimeric Sindbis-based vaccine protects cynomolgus macaques against a lethal aerosol challenge of eastern equine encephalitis virus

Roy, C. J., Adams, A. P., Wang, E., Leal, G., Seymour, R. L., Sivasubramani, S. K., Mega, W., Frolov, I., Didier, P. J. & Weaver, S. C., Jan 24 2013, In : Vaccine. 31, 11, p. 1464-1470 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

A chimeric vesiculo/alphavirus is an effective alphavirus vaccine

Chattopadhyay, A., Wang, E., Seymour, R., Weaver, S. C. & Rose, J. K., Jan 2013, In : Journal of virology. 87, 1, p. 395-402 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

A Comparison of the Nucleotide Sequences of Eastern and Western Equine Encephalomyelitis Viruses with Those of Other Alphaviruses and Related RNA Viruses

Weaver, S. C., Hagenbaugh, A., Bellew, L. A., Netesov, S. V., Volchkov, V. E., Chang, G. J. J., Clarke, D. K., Gousset, L., Scott, T. W., Trent, D. & Holland, J. J., Nov 1993, In : Virology. 197, 1, p. 375-390 16 p., 71599.

Research output: Contribution to journalArticle

77 Scopus citations

Adverse event following live attenuated chikungunya vaccine in a cynomolgus macaque with pre-existing chronic hydrocephalus

Peterson, T. A., MacLean, A. G., Russell-Lodrigue, K. E., Didier, P. J., Weaver, S. C. & Roy, C. J., Aug 2019, In : Journal of Medical Primatology. 48, 4, p. 257-259 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

A five-amino-acid deletion of the eastern equine encephalitis virus capsid protein attenuates replication in mammalian systems but not in mosquito cells

Aguilar, P. V., Leung, L. W., Wang, E., Weaver, S. C. & Basler, C. F., Jul 2008, In : Journal of virology. 82, 14, p. 6972-6983 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

African and asian zika virus isolates display phenotypic differences both in vitro and in vivo

Smith, D. R., Sprague, T. R., Hollidge, B. S., Valdez, S. M., Padilla, S. L., Bellanca, S. A., Golden, J. W., Coyne, S. R., Kulesh, D. A., Miller, L. J., Haddow, A. D., Koehler, J. W., Gromowski, G. D., Jarman, R. G., Alera, M. T. P., Yoon, I. K., Buathong, R., Lowen, R. G., Kane, C. D., Minogue, T. D. & 6 others, Bavari, S., Tesh, R. B., Weaver, S., Linthicum, K. J., Pitt, M. L. & Nasar, F., Jan 1 2018, In : American Journal of Tropical Medicine and Hygiene. 98, 2, p. 432-444 13 p.

Research output: Contribution to journalArticle

29 Scopus citations

Alignment algorithms and per-particle CTF correction for single particle cryo-electron tomography

Galaz-Montoya, J. G., Hecksel, C. W., Baldwin, P. R., Wang, E., Weaver, S., Schmid, M. F., Ludtke, S. J. & Chiu, W., Jun 1 2016, In : Journal of Structural Biology. 194, 3, p. 383-394 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models

Shan, C., Muruato, A. E., Nunes, B. T. D., Luo, H., Xie, X., Medeiros, D. B. A., Wakamiya, M., Tesh, R. B., Barrett, A. D., Wang, T., Weaver, S. C., Vasconcelos, P. F. C., Rossi, S. L. & Shi, P. Y., Jun 1 2017, In : Nature Medicine. 23, 6, p. 763-767 5 p.

Research output: Contribution to journalArticle

143 Scopus citations

Allpahuayo virus: A newly recognized arenavirus (Arenaviridae) from arboreal rice rats (Oecomys Bicolor and Oecomys Paricola) in Northeastern Peru

Moncayo, A. C., Hice, C. L., Watts, D. M., Travassos De Rosa, A. P. A., Guzman, H., Russell, K. L., Calampa, C., Gozalo, A., Popov, V. L., Weaver, S. C. & Tesh, R. B., Jun 5 2001, In : Virology. 284, 2, p. 277-286 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Alpha-beta T cells provide protection against lethal encephalitis in the murine model of VEEV infection

Paessler, S., Yun, N. E., Judy, B. M., Dziuba, N., Zacks, M. A., Grund, A. H., Frolov, I., Campbell, G. A., Weaver, S. C. & Estes, D. M., Oct 25 2007, In : Virology. 367, 2, p. 307-323 17 p.

Research output: Contribution to journalArticle

46 Scopus citations

Alphaviral Encephalitides

Weaver, S. C. & Paessler, S., Dec 1 2009, Vaccines for Biodefense and Emerging and Neglected Diseases. Elsevier Inc., p. 339-359 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations

Alphaviruses: Equine encephalitis and others

Weaver, S. & Powers, A. M., Jun 1 2014, Viral Infections of Humans: Epidemiology and Control. Springer US, Vol. 9781489974488. p. 123-145 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Alphaviruses: Population genetics and determinants of emergence

Weaver, S. C., Winegar, R., Manger, I. D. & Forrester, N. L., Jun 1 2012, In : Antiviral research. 94, 3, p. 242-257 16 p.

Research output: Contribution to journalReview article

74 Scopus citations

Alphaviruses in Latin America and the introduction of chikungunya virus

Navarro, J. C., Carrera, J. P., Liria, J., Auguste, A. & Weaver, S. C., Jul 19 2017, Human Virology in Latin America: From Biology to Control. Springer International Publishing, p. 169-192 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Alphavirus Infections

Weaver, S. C. & Smith, D. W., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 519-524 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Alphavirus Infections

Weaver, S. C., Tesh, R. B. & Shope, R. E., Jan 1 2006, Tropical Infectious Diseases. Elsevier Inc., Vol. 1. p. 831-838 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Alphavirus production is inhibited in neurofibromin 1-deficient cells through activated RAS signalling

Kolokoltsova, O. A., Domina, A. M., Kolokoltsov, A. A., Davey, R. A., Weaver, S. C. & Watowich, S. J., Jul 20 2008, In : Virology. 377, 1, p. 133-142 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

A Multicomponent Animal Virus Isolated from Mosquitoes

Ladner, J. T., Wiley, M. R., Beitzel, B., Auguste, A. J., Dupuis, A. P., Lindquist, M. E., Sibley, S. D., Kota, K. P., Fetterer, D., Eastwood, G., Kimmel, D., Prieto, K., Guzman, H., Aliota, M. T., Reyes, D., Brueggemann, E. E., St. John, L., Hyeroba, D., Lauck, M., Friedrich, T. C. & 15 others, O'Connor, D. H., Gestole, M. C., Cazares, L. H., Popov, V., Castro-Llanos, F., Kochel, T. J., Kenny, T., White, B., Ward, M. D., Loaiza, J. R., Goldberg, T. L., Weaver, S., Kramer, L. D., Tesh, R. B. & Palacios, G., Sep 14 2016, In : Cell Host and Microbe. 20, 3, p. 357-367 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

An adjuvanted adenovirus 5-based vaccine elicits neutralizing antibodies and protects mice against chikungunya virus-induced footpad swelling

Dora, E. G., Rossi, S., Weaver, S., Tucker, S. N. & Mateo, R., Jan 1 2019, In : Vaccine.

Research output: Contribution to journalArticle

2 Scopus citations

Analysis of intrahost variation in Venezuelan equine encephalitis virus reveals repeated deletions in the 6-kilodalton protein gene

Forrester, N. L., Guerbois, M., Adams, A. P., Liang, X. & Weaver, S. C., Sep 2011, In : Journal of virology. 85, 17, p. 8709-8717 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Analysis of Venezuelan equine encephalitis virus capsid protein function in the inhibition of cellular transcription

Garmashova, N., Atasheva, S., Kang, W., Weaver, S. C., Frolova, E. & Frolov, I., Dec 2007, In : Journal of virology. 81, 24, p. 13552-13565 14 p.

Research output: Contribution to journalArticle

86 Scopus citations

An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

Xia, H., Luo, H., Shan, C., Muruato, A. E., Nunes, B. T. D., Medeiros, D. B. A., Zou, J., Xie, X., Giraldo, M. I., Vasconcelos, P. F. C., Weaver, S. C., Wang, T., Rajsbaum, R. & Shi, P. Y., Dec 1 2018, In : Nature communications. 9, 1, 414.

Research output: Contribution to journalArticle

79 Scopus citations

A newly isolated reovirus has the simplest genomic and structural organization of any reovirus

Auguste, A. J., Kaelber, J. T., Fokam, E. B., Guzman, H., Carrington, C. V. F., Erasmus, J. H., Kamgang, B., Popov, V. L., Jakana, J., Liu, X., Wood, T. G., Widen, S. G., Vasilakis, N., Tesh, R. B., Chiu, W. & Weaver, S. C., Jan 1 2015, In : Journal of virology. 89, 1, p. 676-687 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

An Infectious cDNA Clone of SARS-CoV-2

Xie, X., Muruato, A., Lokugamage, K. G., Narayanan, K., Zhang, X., Zou, J., Liu, J., Schindewolf, C., Bopp, N. E., Aguilar, P. V., Plante, K. S., Weaver, S. C., Makino, S., LeDuc, J. W., Menachery, V. D. & Shi, P. Y., May 13 2020, In : Cell Host and Microbe. 27, 5, p. 841-848.e3

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors

Shan, C., Xie, X., Muruato, A. E., Rossi, S. L., Roundy, C. M., Azar, S. R., Yang, Y., Tesh, R. B., Bourne, N., Barrett, A. D., Vasilakis, N., Weaver, S. C. & Shi, P. Y., Jun 8 2016, In : Cell Host and Microbe. 19, 6, p. 891-900 10 p.

Research output: Contribution to journalArticle

147 Scopus citations

A novel, rapid assay for detection and differentiation of serotype-specific antibodies to Venezuelan equine encephalitis complex alphaviruses

Wang, E., Paessler, S., Aguilar, P. V., Smith, D. R., Coffey, L. L., Kang, W., Pfeffer, M., Olson, J., Blair, P. J., Guevara, C., Estrada-Franco, J. & Weaver, S. C., Jun 2005, In : American Journal of Tropical Medicine and Hygiene. 72, 6, p. 805-810 6 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

A Novel Live-Attenuated Vaccine Candidate for Mayaro Fever

Weise, W. J., Hermance, M. E., Forrester, N., Adams, A. P., Langsjoen, R., Gorchakov, R., Wang, E., Alcorn, M. D. H., Tsetsarkin, K. & Weaver, S. C., Aug 7 2014, In : PLoS neglected tropical diseases. 8, 8, e2969.

Research output: Contribution to journalArticle

24 Scopus citations

Approach to Strain Selection and the Propagation of Viral Stocks for Venezuelan Equine Encephalitis Virus Vaccine Efficacy Testing under the Animal Rule

Rusnak, J. M., Glass, P. J., Weaver, S. C., Sabourin, C. L., Glenn, A. M., Klimstra, W., Badorrek, C. S., Nasar, F. & Ward, L. A., Aug 31 2019, In : Viruses. 11, 9

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

A proposal to change existing virus species names to non-Latinized binomials

van Regenmortel, M. H. V., Burke, D. S., Calisher, C. H., Dietzgen, R. G., Fauquet, C. M., Ghabrial, S. A., Jahrling, P. B., Johnson, K. M., Holbrook, M. R., Horzinek, M. C., Keil, G. M., Kuhn, J. H., Mahy, B. W. J., Martelli, G. P., Pringle, C., Rybicki, E. P., Skern, T., Tesh, R. B., Wahl-Jensen, V., Walker, P. J. & 1 others, Weaver, S. C., Nov 2010, In : Archives of virology. 155, 11, p. 1909-1919 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Arboviral bottlenecks and challenges to maintaining diversity and fitness during mosquito transmission

Forrester, N. L., Coffey, L. L. & Weaver, S. C., Oct 23 2014, In : Viruses. 6, 10, p. 3991-4004 14 p.

Research output: Contribution to journalReview article

36 Scopus citations

Arboviruses: Alphaviruses, flaviviruses and bunyaviruses: Encephalitis; yellow fever; dengue; haemorrhagic fever; miscellaneous tropical fevers; undifferentiated fever

Barrett, A. D. T. & Weaver, S. C., Jul 23 2012, Medical Microbiology: Eighteenth Edition. Elsevier Inc., p. 520-536 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Arbovirus Evolution

Hanley, K. A. & Weaver, S. C., Dec 1 2008, Origin and Evolution of Viruses. Elsevier Ltd, p. 351-391 41 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

22 Scopus citations

Arbovirus evolution in vivo is constrained by host alternation

Coffey, L. L., Vasilakis, N., Brault, A. C., Powers, A. M., Tripet, F. R. & Weaver, S. C., May 13 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 19, p. 6970-6975 6 p.

Research output: Contribution to journalArticle

133 Scopus citations

A recombinant virus vaccine that protects against both Chikungunya and Zika virus infections

Chattopadhyay, A., Aguilar, P. V., Bopp, N. E., Yarovinsky, T. O., Weaver, S. C. & Rose, J. K., Jun 22 2018, In : Vaccine. 36, 27, p. 3894-3900 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

A rodent model of chikungunya virus infection in RAG1 -/- mice, with features of persistence, for vaccine safety evaluation

Seymour, R. L., Adams, A. P., Leal, G., Alcorn, M. D. H. & Weaver, S. C., Jun 26 2015, In : PLoS neglected tropical diseases. 9, 6, e0003800.

Research output: Contribution to journalArticle

16 Scopus citations

Arrangement of the Polymerase Complexes inside a Nine-Segmented dsRNA Virus

Kaelber, J. T., Jiang, W., Weaver, S. C., Auguste, A. & Chiu, W., Jun 2 2020, In : Structure. 28, 6, p. 604-612.e3

Research output: Contribution to journalArticle

1 Scopus citations
174 Scopus citations

A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

Shan, C., Muruato, A. E., Jagger, B. W., Richner, J., Nunes, B. T. D., Medeiros, D. B. A., Xie, X., Nunes, J. G. C., Morabito, K. M., Kong, W. P., Pierson, T. C., Barrett, A. D., Weaver, S. C., Rossi, S. L., Vasconcelos, P. F. C., Graham, B. S., Diamond, M. S. & Shi, P. Y., Dec 1 2017, In : Nature communications. 8, 1, 676.

Research output: Contribution to journalArticle

70 Scopus citations

A Single-Dose Live-Attenuated Zika Virus Vaccine with Controlled Infection Rounds that Protects against Vertical Transmission

Xie, X., Kum, D. B., Xia, H., Luo, H., Shan, C., Zou, J., Muruato, A. E., Medeiros, D. B. A., Nunes, B. T. D., Dallmeier, K., Rossi, S. L., Weaver, S. C., Neyts, J., Wang, T., Vasconcelos, P. F. C. & Shi, P. Y., Oct 10 2018, In : Cell Host and Microbe. 24, 4, p. 487-499.e5

Research output: Contribution to journalArticle

19 Scopus citations

A single-dose plasmid-launched live-attenuated Zika vaccine induces protective immunity

Zou, J., Xie, X., Luo, H., Shan, C., Muruato, A. E., Weaver, S. C., Wang, T. & Shi, P. Y., Oct 2018, In : EBioMedicine. 36, p. 92-102 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Assessing the epidemiological effect of wolbachia for dengue control

Lambrechts, L., Ferguson, N. M., Harris, E., Holmes, E. C., McGraw, E. A., O'Neill, S. L., Ooi, E. E., Ritchie, S. A., Ryan, P. A., Scott, T. W., Simmons, C. P. & Weaver, S. C., Jul 1 2015, In : The Lancet Infectious Diseases. 15, 7, p. 862-866 5 p.

Research output: Contribution to journalComment/debate

41 Scopus citations

Association of Venezuelan equine encephalitis virus subtype IE with two equine epizootics in Mexico

Oberste, M. S., Fraire, M., Navarro, R., Zepeda, C., Zarate, M. L., Ludwig, G. V., Kondig, J. F., Weaver, S. C., Smith, J. F. & Rico-Hesse, R., Jan 1 1998, In : American Journal of Tropical Medicine and Hygiene. 59, 1, p. 100-107 8 p.

Research output: Contribution to journalArticle

Open Access
60 Scopus citations

Attenuation of chikungunya virus vaccine strain 181/clone 25 is determined by two amino acid substitutions in the e2 envelope glycoprotein

Gorchakov, R., Wang, E., Leal, G., Forrester, N. L., Plante, K., Rossi, S. L., Partidos, C. D., Adams, A. P., Seymour, R. L., Weger, J., Borland, E. M., Sherman, M. B., Powers, A. M., Osorio, J. E. & Weaver, S. C., Jun 2012, In : Journal of virology. 86, 11, p. 6084-6096 13 p.

Research output: Contribution to journalArticle

86 Scopus citations

Author's correction: Genome-scale phylogenetic analyses of chikungunya virus reveal independent emergences of recent epidemics and various evolutionary rates

Volk, S. M., Chen, R., Tsetsarkin, K. A., Adams, A. P., Garcia, T. I., Sall, A. A., Nasar, F., Schuh, A. J., Holmes, E. C., Higgs, S., Maharaj, P. D., Brault, A. C. & Weaver, S. C., Jun 1 2011, In : Journal of virology. 85, 11, 1 p.

Research output: Contribution to journalComment/debate

A vaccine candidate for eastern equine encephalitis virus based on IRES-mediated attenuation

Pandya, J., Gorchakov, R., Wang, E., Leal, G. & Weaver, S. C., Feb 8 2012, In : Vaccine. 30, 7, p. 1276-1282 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Barriers to dissemination of Venezuelan encephalitis viruses in the Middle American enzootic vector mosquito Culex (Melanoconion) taeniopus

Weaver, S. C., Scherer, W. F., Cupp, E. W. & Castello, D. A., Jan 1 1984, In : American Journal of Tropical Medicine and Hygiene. 33, 5, p. 953-960 8 p.

Research output: Contribution to journalArticle

30 Scopus citations