Scott Weaver, PhD, MS

Chair

  • 20302 Citations
  • 74 h-Index
1981 …2020

Research output per year

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Research Output

2011

Erratum: Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 38 (15978-15983) DOI: 10.1073/pnas.1108558108)

Zasloff, M., Adams, A. P., Beckerman, B., Campbell, A., Han, Z., Luijten, E., Meza, I., Julander, J., Mishra, A., Qu, W., Taylor, J. M., Weaver, S. C. & Wong, G. C. L., Nov 1 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 44, p. 18186 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Erratum to "Stability of RNA virus attenuation approaches" [Vaccine 29 (2011) 2230-2234]

Kenney, J. L., Volk, S. M., Pandya, J., Wang, E., Liang, X. & Weaver, S. C., Oct 19 2011, In : Vaccine. 29, 45, 1 p.

Research output: Contribution to journalComment/debate

Fever from the forest: Prospects for the continued emergence of sylvatic dengue virus and its impact on public health

Vasilakis, N., Cardosa, J., Hanley, K. A., Holmes, E. C. & Weaver, S. C., May 2011, In : Nature Reviews Microbiology. 9, 7, p. 532-541 10 p.

Research output: Contribution to journalReview article

169 Scopus citations

Novel chikungunya vaccine candidate with an ires-based attenuation and host range alteration mechanism

Plante, K., Wang, E., Partidos, C. D., Weger, J., Gorchakov, R., Tsetsarkin, K., Borland, E. M., Powers, A. M., Seymour, R., Stinchcomb, D. T., Osorio, J. E., Frolov, I. & Weaver, S. C., Jul 2011, In : PLoS pathogens. 7, 7, e1002142.

Research output: Contribution to journalArticle

116 Scopus citations

Probing the attenuation and protective efficacy of a candidate chikungunya virus vaccine in mice with compromised interferon (IFN) signaling

Partidos, C. D., Weger, J., Brewoo, J., Seymour, R., Borland, E. M., Ledermann, J. P., Powers, A. M., Weaver, S. C., Stinchcomb, D. T. & Osorio, J. E., Apr 5 2011, In : Vaccine. 29, 16, p. 3067-3073 7 p.

Research output: Contribution to journalArticle

51 Scopus citations

Sequential adaptive mutations enhance efficient vector switching by chikungunya virus and its epidemic emergence

Tsetsarkin, K. A. & Weaver, S. C., Dec 2011, In : PLoS pathogens. 7, 12, e1002412.

Research output: Contribution to journalArticle

150 Scopus citations

Serologic evidence of arboviral infections among humans in Kenya

Sutherland, L. J., Cash, A. A., Huang, Y. J. S., Sang, R. C., Malhotra, I., Moormann, A. M., King, C. L., Weaver, S. C., King, C. H. & LaBeaud, A. D., Jul 2011, In : American Journal of Tropical Medicine and Hygiene. 85, 1, p. 158-161 4 p.

Research output: Contribution to journalArticle

49 Scopus citations

Squalamine as a broad-spectrum systemic antiviral agent with therapeutic potential

Zasloff, M., Adams, A. P., Beckerman, B., Campbell, A., Han, Z., Luijten, E., Meza, I., Julander, J., Mishra, A., Qu, W., Taylor, J. M., Weaver, S. C. & Wong, G. C. L., Oct 20 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 38, p. 15978-15983 6 p.

Research output: Contribution to journalArticle

61 Scopus citations

Stability of RNA virus attenuation approaches

Kenney, J. L., Volk, S. M., Pandya, J., Wang, E., Liang, X. & Weaver, S. C., Feb 8 2011, In : Vaccine. 29, 12, p. 2230-2234 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

The structure of barmah forest virus as revealed by cryo-electron microscopy at a 6-angstrom resolution has detailed transmembrane protein architecture and interactions

Kostyuchenko, V. A., Jakana, J., Liu, X., Haddow, A. D., Aung, M., Weaver, S. C., Chiu, W. & Lok, S. M., Sep 2011, In : Journal of virology. 85, 18, p. 9327-9333 7 p.

Research output: Contribution to journalArticle

35 Scopus citations
12 Scopus citations

Use of Sindbis/eastern equine encephalitis chimeric viruses in plaque reduction neutralization tests for arboviral disease diagnostics

Johnson, B. W., Kosoy, O., Wang, E., Delorey, M., Russell, B., Bowen, R. A. & Weaver, S. C., Sep 2011, In : Clinical and Vaccine Immunology. 18, 9, p. 1486-1491 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
2012

Alphaviruses: Population genetics and determinants of emergence

Weaver, S. C., Winegar, R., Manger, I. D. & Forrester, N. L., Jun 1 2012, In : Antiviral research. 94, 3, p. 242-257 16 p.

Research output: Contribution to journalReview article

77 Scopus citations

Arboviruses: Alphaviruses, flaviviruses and bunyaviruses: Encephalitis; yellow fever; dengue; haemorrhagic fever; miscellaneous tropical fevers; undifferentiated fever

Barrett, A. D. T. & Weaver, S. C., Jul 23 2012, Medical Microbiology: Eighteenth Edition. Elsevier Inc., p. 520-536 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Attenuation of chikungunya virus vaccine strain 181/clone 25 is determined by two amino acid substitutions in the e2 envelope glycoprotein

Gorchakov, R., Wang, E., Leal, G., Forrester, N. L., Plante, K., Rossi, S. L., Partidos, C. D., Adams, A. P., Seymour, R. L., Weger, J., Borland, E. M., Sherman, M. B., Powers, A. M., Osorio, J. E. & Weaver, S. C., Jun 2012, In : Journal of virology. 86, 11, p. 6084-6096 13 p.

Research output: Contribution to journalArticle

89 Scopus citations

A vaccine candidate for eastern equine encephalitis virus based on IRES-mediated attenuation

Pandya, J., Gorchakov, R., Wang, E., Leal, G. & Weaver, S. C., Feb 8 2012, In : Vaccine. 30, 7, p. 1276-1282 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Chikungunya virus and prospects for a vaccine

Weaver, S. C., Osorio, J. E., Livengood, J. A., Chen, R. & Stinchcomb, D. T., Sep 1 2012, In : Expert review of vaccines. 11, 9, p. 1087-1101 15 p.

Research output: Contribution to journalReview article

155 Scopus citations

Cross-protective immunity against o'nyong-nyong virus afforded by a novel recombinant chikungunya vaccine

Partidos, C. D., Paykel, J., Weger, J., Borland, E. M., Powers, A. M., Seymour, R., Weaver, S. C., Stinchcomb, D. T. & Osorio, J. E., Jun 29 2012, In : Vaccine. 30, 31, p. 4638-4643 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Cryo-EM Reconstruction Of Eilat Alphavirus

Sherman, M., Nasar, F. & Weaver, S., 2012, In : Microscopy and Microanalysis. 18, p. 74-75 2 p.

Research output: Contribution to journalArticle

Eilat virus, a unique alphavirus with host range restricted to insects by RNA replication

Nasar, F., Palacios, G., Gorchakov, R. V., Guzman, H., Travassos Da Rosa, A. P., Savji, N., Popov, V. L., Sherman, M. B., Lipkin, W. I., Tesh, R. B. & Weaver, S. C., Sep 4 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 36, p. 14622-14627 6 p.

Research output: Contribution to journalArticle

93 Scopus citations

Genetic and anatomic determinants of enzootic Venezuelan equine encephalitis virus infection of Culex (Melanoconion) taeniopus

Kenney, J. L., Adams, A. P., Gorchakov, R., Leal, G. & Weaver, S. C., Apr 2012, In : PLoS neglected tropical diseases. 6, 4, e1606.

Research output: Contribution to journalArticle

10 Scopus citations

Genetic and phenotypic characterization of sylvatic dengue virus type 4 strains

Rossi, S. L., Nasar, F., Cardosa, J., Mayer, S. V., Tesh, R. B., Hanley, K. A., Weaver, S. C. & Vasilakis, N., Feb 5 2012, In : Virology. 423, 1, p. 58-67 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Genetic characterization of zika virus strains: Geographic expansion of the asian lineage

Haddow, A. D., Schuh, A. J., Yasuda, C. Y., Kasper, M. R., Heang, V., Huy, R., Guzman, H., Tesh, R. B. & Weaver, S. C., Feb 2012, In : PLoS neglected tropical diseases. 6, 2, e1477.

Research output: Contribution to journalArticle

461 Scopus citations

Genome-scale phylogeny of the alphavirus genus suggests a marine origin

Forrester, N. L., Palacios, G., Tesh, R. B., Savji, N., Guzman, H., Sherman, M., Weaver, S. C. & Lipkin, W. I., Mar 2012, In : Journal of virology. 86, 5, p. 2729-2738 10 p.

Research output: Contribution to journalArticle

77 Scopus citations

Landscape ecology of sylvatic chikungunya virus and mosquito vectors in southeastern senegal

Diallo, D., Sall, A. A., Buenemann, M., Chen, R., Faye, O., Diagne, C. T., Faye, O., Ba, Y., Dia, I., Watts, D., Weaver, S. C., Hanley, K. A. & Diallo, M., Jun 2012, In : PLoS neglected tropical diseases. 6, 6, e1649.

Research output: Contribution to journalArticle

67 Scopus citations

Larval ecology of mosquitoes in sylvatic arbovirus foci in southeastern Senegal

Diallo, D., Diagne, C. T., Hanley, K. A., Sall, A. A., Buenemann, M., Ba, Y., Dia, I., Weaver, S. C. & Diallo, M., 2012, In : Parasites and Vectors. 5, 1, 286.

Research output: Contribution to journalArticle

23 Scopus citations

Preclinical Evaluation of a Live Attenuated Chikungunya Vaccine

Livengood, J. A., Partidos, C. D., Plante, K., Seymour, R., Gorchakov, R., Varga, L., Paykel, J., Weger, J., Haller, A., Stinchcomb, D. T., Osorio, J. & Weaver, S., May 7 2012, In : Procedia in Vaccinology. 6, p. 141-149 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Recommendations for publication of viral genetic data and sample access for novel viruses and strains

Arrigo, N. C., Briese, T., Calisher, C. H., Drebot, M. A., Hjelle, B., LeDuc, J. W., Powers, A. M., Repik, P. M., Roehrig, J. T., Schmaljohn, C. S., Tesh, R. B. & Weaver, S. C., Feb 2012, In : American Journal of Tropical Medicine and Hygiene. 86, 2, p. 189-191 3 p.

Research output: Contribution to journalShort survey

2 Scopus citations

Serological evidence of flaviviruses and alphaviruses in Livestock and Wildlife in Trinidad

Thompson, N. N., Auguste, A. J., Coombs, D., Blitvich, B. J., Carrington, C. V. F., Da Rosa, A. P. T., Wang, E., Chadee, D. D., Drebot, M. A., Tesh, R. B., Weaver, S. C. & Adesiyun, A. A., Nov 1 2012, In : Vector-Borne and Zoonotic Diseases. 12, 11, p. 969-978 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Synchrony of Sylvatic Dengue Isolations: A Multi-Host, Multi-Vector SIR Model of Dengue Virus Transmission in Senegal

Althouse, B. M., Lessler, J., Sall, A. A., Diallo, M., Hanley, K. A., Watts, D. M., Weaver, S. C. & Cummings, D. A. T., Nov 2012, In : PLoS neglected tropical diseases. 6, 11, e1928.

Research output: Contribution to journalArticle

26 Scopus citations

Vector-Borne Transmission Imposes a Severe Bottleneck on an RNA Virus Population

Forrester, N. L., Guerbois, M., Seymour, R. L., Spratt, H. & Weaver, S. C., Sep 2012, In : PLoS pathogens. 8, 9, e1002897.

Research output: Contribution to journalArticle

72 Scopus citations

Venezuelan Equine Encephalitis Virus Activity in the Gulf Coast Region of Mexico, 2003-2010

Adams, A. P., Navarro-Lopez, R., Ramirez-Aguilar, F. J., Lopez-Gonzalez, I., Leal, G., Flores-Mayorga, J. M., Travassos da Rosa, A. P. A., Saxton-Shaw, K. D., Singh, A. J., Borland, E. M., Powers, A. M., Tesh, R. B., Weaver, S. C. & Estrada-Franco, J. G., Nov 2012, In : PLoS neglected tropical diseases. 6, 11, e1875.

Research output: Contribution to journalArticle

25 Scopus citations

VIPR HMM: A hidden Markov model for detecting recombination with microbial detection microarrays

Allred, A. F., Renshaw, H., Weaver, S., Tesh, R. B. & Wang, D., Nov 2012, In : Bioinformatics. 28, 22, p. 2922-2929 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Viral CNS Infections: Venezuelan, Eastern and Western Equine Encephalitis

Weaver, S. C. & LaBeaud, A. D., Nov 1 2012, Hunter's Tropical Medicine and Emerging Infectious Disease: Ninth Edition. Elsevier Inc., p. 354-358 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2013

A chimeric Sindbis-based vaccine protects cynomolgus macaques against a lethal aerosol challenge of eastern equine encephalitis virus

Roy, C. J., Adams, A. P., Wang, E., Leal, G., Seymour, R. L., Sivasubramani, S. K., Mega, W., Frolov, I., Didier, P. J. & Weaver, S. C., Jan 24 2013, In : Vaccine. 31, 11, p. 1464-1470 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

A chimeric vesiculo/alphavirus is an effective alphavirus vaccine

Chattopadhyay, A., Wang, E., Seymour, R., Weaver, S. C. & Rose, J. K., Jan 2013, In : Journal of virology. 87, 1, p. 395-402 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

Bloodfeeding patterns of sylvatic arbovirus vectors in southeastern Senegal

Diallo, D., Chen, R., Diagne, C. T., Ba, Y., Dia, I., Sall, A. A., Weaver, S. C. & Diallo, M., Mar 2013, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 107, 3, p. 200-203 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

Chikungunya Virus 3′ Untranslated Region: Adaptation to Mosquitoes and a Population Bottleneck as Major Evolutionary Forces

Chen, R., Wang, E., Tsetsarkin, K. A. & Weaver, S. C., Aug 2013, In : PLoS pathogens. 9, 8, e1003591.

Research output: Contribution to journalArticle

49 Scopus citations

Construction and organization of a BSL-3 cryo-electron microscopy laboratory at UTMB

Sherman, M. B., Trujillo, J., Leahy, I., Razmus, D., DeHate, R., Lorcheim, P., Czarneski, M. A., Zimmerman, D., Newton, J. T. A. M., Haddow, A. D. & Weaver, S. C., Mar 2013, In : Journal of Structural Biology. 181, 3, p. 223-233 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Deciphering the protective role of adaptive immunity to CHIKV/IRES a novel candidate vaccine against Chikungunya in the A129 mouse model

Chu, H., Das, S. C., Fuchs, J. F., Suresh, M., Weaver, S. C., Stinchcomb, D. T., Partidos, C. D. & Osorio, J. E., Jul 18 2013, In : Vaccine. 31, 33, p. 3353-3360 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Eastern equine encephalitis in Latin America

Carrera, J. P., Forrester, N., Wang, E., Vittor, A. Y., Haddow, A. D., Loṕez-Vergès, S., Abadiá, I., Castanõ, E., Sosa, N., Baéz, C., Estripeaut, D., Diáz, Y., Beltrań, D., Cisneros, J., Cedeño, H. G., Da Rosa, A. P. T., Hernandez, H., Martínez-Torres, A. O., Tesh, R. B. & Weaver, S. C., 2013, In : New England Journal of Medicine. 369, 8, p. 732-744 13 p.

Research output: Contribution to journalArticle

50 Scopus citations

Emergence potential of sylvatic dengue virus type 4 in the urban transmission cycle is restrained by vaccination and homotypic immunity

Durbin, A. P., Mayer, S. V., Rossi, S. L., Amaya-Larios, I. Y., Ramos-Castaneda, J., Eong Ooi, E., Jane Cardosa, M., Munoz-Jordan, J. L., Tesh, R. B., Messer, W. B., Weaver, S. C. & Vasilakis, N., Apr 25 2013, In : Virology. 439, 1, p. 34-41 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Factors shaping the adaptive landscape for arboviruses: Implications for the emergence of disease

Coffey, L. L., Forrester, N., Tsetsarkin, K., Vasilakis, N. & Weaver, S. C., Feb 2013, In : Future Microbiology. 8, 2, p. 155-176 22 p.

Research output: Contribution to journalReview article

75 Scopus citations
82 Scopus citations

First isolation of Aedes flavivirus in the Western Hemisphere and evidence of vertical transmission in the mosquito Aedes (Stegomyia) albopictus (Diptera: Culicidae)

Haddow, A. D., Guzman, H., Popov, V. L., Wood, T. G., Widen, S. G., Haddow, A. D., Tesh, R. B. & Weaver, S. C., Jun 5 2013, In : Virology. 440, 2, p. 134-139 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

GeneSV - An approach to help characterize possible variations in genomic and protein sequences

Zemla, A., Kostova, T., Gorchakov, R., Volkova, E., Beasley, D. W., Cardosa, J., Weaver, S., Vasilakis, N. & Naraghi-Arani, P., Oct 31 2013, In : Bioinformatics and Biology Insights. 8, p. 1-16 16 p.

Research output: Contribution to journalArticle

2 Scopus citations

Identification of dengue fever cases in Houston, Texas, with evidence of autochthonous transmission between 2003 and 2005

Murray, K. O., Rodriguez, L. F., Herrington, E., Kharat, V., Vasilakis, N., Walker, C., Turner, C., Khuwaja, S., Arafat, R., Weaver, S. C., Martinez, D., Kilborn, C., Bueno, R. & Reyna, M., Dec 1 2013, In : Vector-Borne and Zoonotic Diseases. 13, 12, p. 835-845 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

IRES-based Venezuelan equine encephalitis vaccine candidate elicits protective immunity in mice

Rossi, S. L., Guerbois, M., Gorchakov, R., Plante, K. S., Forrester, N. L. & Weaver, S. C., Mar 15 2013, In : Virology. 437, 2, p. 81-88 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

IRES-driven Expression of the Capsid Protein of the Venezuelan Equine Encephalitis Virus TC-83 Vaccine Strain Increases Its Attenuation and Safety

Guerbois, M., Volkova, E., Forrester, N. L., Rossi, S. L., Frolov, I. & Weaver, S. C., May 2013, In : PLoS neglected tropical diseases. 7, 5, e2197.

Research output: Contribution to journalArticle

17 Scopus citations

Legal, technical, and interpretational considerations in the forensic analysis of viruses

Wilson, M. R., Weaver, S. C. & Winegar, R. A., Mar 1 2013, In : Journal of Forensic Sciences. 58, 2, p. 344-357 14 p.

Research output: Contribution to journalArticle

4 Scopus citations