Shannon Clark, MD, MMS

  • 700 Citations
  • 14 h-Index
19992020

Research output per year

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Research Output

  • 700 Citations
  • 14 h-Index
  • 35 Article
  • 7 Review article
  • 1 Chapter
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Article
2020

Effects of Pregnancy on the Pharmacokinetics of Metformin

Liao, M. Z., Flood Nichols, S. K., Ahmed, M., Clark, S., Hankins, G. D., Caritis, S., Venkataramanan, R., Haas, D., Quinney, S. K., Haneline, L. S., Tita, A. T., Manuck, T., Wang, J., Thummel, K. E., Brown, L. M., Ren, Z., Easterling, T. R. & Hebert, M. F., Apr 1 2020, In : Drug metabolism and disposition: the biological fate of chemicals. 48, 4, p. 264-271 8 p.

Research output: Contribution to journalArticle

Pharmacodynamics of Glyburide, Metformin, and Glyburide/Metformin Combination Therapy in the Treatment of Gestational Diabetes Mellitus

Shuster, D. L., Shireman, L. M., Ma, X., Shen, D. D., Flood Nichols, S. K., Ahmed, M. S., Clark, S., Caritis, S., Venkataramanan, R., Haas, D. M., Quinney, S. K., Haneline, L. S., Tita, A. T., Manuck, T. A., Thummel, K. E., Brown, L. M., Ren, Z., Brown, Z., Easterling, T. R. & Hebert, M. F., Jun 1 2020, In : Clinical Pharmacology and Therapeutics. 107, 6, p. 1362-1372 11 p.

Research output: Contribution to journalArticle

2019

Pharmacodynamics of Metformin in Pregnant Women With Gestational Diabetes Mellitus and Nonpregnant Women With Type 2 Diabetes Mellitus

Shuster, D. L., Shireman, L. M., Ma, X., Shen, D. D., Flood Nichols, S. K., Ahmed, M. S., Clark, S., Caritis, S., Venkataramanan, R., Haas, D. M., Quinney, S. K., Haneline, L. S., Tita, A. T., Manuck, T. A., Thummel, K. E., Morris Brown, L., Ren, Z., Brown, Z., Easterling, T. R. & Hebert, M. F., Jan 1 2019, (Accepted/In press) In : Journal of clinical pharmacology.

Research output: Contribution to journalArticle

2018

Effect of CYP2C9 Polymorphisms on the Pharmacokinetics of Indomethacin During Pregnancy

Shah, M., Xu, M., Shah, P., Wang, X-M., Clark, S., Costantine, M., West, H. A., Nanovskaya, T., Ahmed, M., Abdel-Rahman, S., Venkataramanan, R., Caritis, S. N., Hankins, G. & Rytting, E., Jan 1 2018, (Accepted/In press) In : European Journal of Drug Metabolism and Pharmacokinetics.

Research output: Contribution to journalArticle

1 Scopus citations

Prednisone Pharmacokinetics During Pregnancy and Lactation

Ryu, R. J., Easterling, T. R., Caritis, S. N., Venkataramanan, R., Umans, J. G., Ahmed, M. S., Clark, S., Kantrowitz-Gordon, I., Hays, K., Bennett, B., Honaker, M. T., Thummel, K. E., Shen, D. D. & Hebert, M. F., Sep 2018, In : Journal of clinical pharmacology. 58, 9, p. 1223-1232 10 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Bupropion sustained release for pregnant smokers: a randomized, placebo-controlled trial

Nanovskaya, T. N., Oncken, C., Fokina, V. M., Feinn, R. S., Clark, S. M., West, H., Jain, S. K., Ahmed, M. S. & Hankins, G. D. V., Apr 1 2017, In : American Journal of Obstetrics and Gynecology. 216, 4, p. 420.e1-420.e9

Research output: Contribution to journalArticle

12 Scopus citations

Hemostatic Resuscitation in Peripartum Hysterectomy Pre- and Postmassive Transfusion Protocol Initiation

Dutta, E. H., Poole, A. T., Behnia, F., Dunn, H. E., Clark, S., Pacheco, L., Saade, G. & Hankins, G., Jan 12 2017, (Accepted/In press) In : American Journal of Perinatology.

Research output: Contribution to journalArticle

1 Scopus citations
2016
11 Scopus citations

Demonstration of early efficacy results of the delayed-release combination of doxylamine-pyridoxine for the treatment of nausea and vomiting of pregnancy

Koren, G., Clark, S., Hankins, G. D. V., Caritis, S. N., Umans, J. G., Miodovnik, M., Mattison, D. R. & Matok, I., Nov 24 2016, In : BMC Pregnancy and Childbirth. 16, 1, 371.

Research output: Contribution to journalArticle

1 Scopus citations

Effectiveness of doxylamine-pyridoxine for morning sickness

Koren, G., Hankins, G., Clark, S., Caritis, S. N., Miodovnik, M., Umans, J. G. & Mattison, D. R., May 1 2016, In : American Journal of Obstetrics and Gynecology. 214, 5, p. 664-666 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Pharmacokinetics of bupropion and its pharmacologically active metabolites in pregnancy

Fokina, V. M., Xu, M., Rytting, E., Abdel-Rahman, S. Z., West, H., Oncken, C., Clark, S. M., Ahmed, M. S., Hankins, G. D. V. & Nanovskaya, T. N., Jan 1 2016, In : Drug Metabolism and Disposition. 44, 11, p. 1832-1838 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Pravastatin Effects on Placental Prosurvival Molecular Pathways in a Mouse Model of Preeclampsia

Saad, A., Diken, Z. M., Kechichian, T. B., Clark, S., Olson, G., Saade, G. & Costantine, M., Nov 1 2016, In : Reproductive Sciences. 23, 11, p. 1593-1599 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
2015

A review of oral labetalol and nifedipine in mild to moderate hypertension in pregnancy

Clark, S., Dunn, H. E. & Hankins, G., Nov 1 2015, In : Seminars in Perinatology. 39, 7, p. 548-555 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Low Back Pain and Pelvic Girdle Pain in Pregnancy

Casagrande, D., Gugala, Z., Clark, S. & Lindsey, R., Sep 26 2015, In : Journal of the American Academy of Orthopaedic Surgeons. 23, 9, p. 539-549 11 p.

Research output: Contribution to journalArticle

39 Scopus citations

Maternal safety of the delayed-release doxylamine and pyridoxine combination for nausea and vomiting of pregnancy; a randomized placebo controlled trial

Koren, G., Clark, S., Hankins, G. D. V., Caritis, S. N., Umans, J. G., Miodovnik, M., Mattison, D. R. & Matok, I., Mar 18 2015, In : BMC Pregnancy and Childbirth. 15, 1, 59.

Research output: Contribution to journalArticle

14 Scopus citations

Population pharmacokinetics of oseltamivir in non-pregnant and pregnant women

Pillai, V. C., Han, K., Beigi, R. H., Hankins, G. D., Clark, S., Hebert, M. F., Easterling, T. R., Zajicek, A., Ren, Z., Caritis, S. N. & Venkataramanan, R., Nov 1 2015, In : British Journal of Clinical Pharmacology. 80, 5, p. 1042-1050 9 p.

Research output: Contribution to journalArticle

9 Scopus citations
2014

Pharmacokinetics of indomethacin in pregnancy

Rytting, E., Nanovskaya, T. N., Wang, X., Vernikovskaya, D. I., Clark, S. M., Cochran, M., Abdel-Rahman, S. M., Venkataramanan, R., Caritis, S. N., Hankins, G. D. V. & Ahmed, M. S., Jun 2014, In : Clinical Pharmacokinetics. 53, 6, p. 545-551 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Studying the antiemetic effect of vitamin B6 for morning sickness: pyridoxine and pyridoxal are prodrugs

Matok, I., Clark, S., Caritis, S., Miodovnik, M., Umans, J. G., Hankins, G., Mattison, D. R. & Koren, G., Dec 1 2014, In : Journal of Clinical Pharmacology. 54, 12, p. 1429-1433 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
2013

Characteristics of women with nausea and vomiting of pregnancy who chose to continue compassionate use of placebo after a randomised trial

Matok, I., Umans, J., Feghali, M. N., Clark, S., Caritis, S., Miodovnik, M., Hankins, G., Mattison, D. R., Nordeng, H. & Koren, G., Aug 1 2013, In : Journal of Obstetrics and Gynaecology. 33, 6, p. 557-560 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Comparing the pharmacokinetics of doxylamine/pyridoxine delayed-release combination in nonpregnant women of reproductive age and women in the first trimester of pregnancy

Matok, I., Clark, S., Caritis, S., Miodovnik, M., Umans, J., Hankins, G. & Koren, G., Mar 1 2013, In : Journal of clinical pharmacology. 53, 3, p. 334-338 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Intrapartum asphyxia, neonatal encephalopathy, cerebral palsy, and obstetric interventions in the term and near-term infant

Clark, S. M., Basraon, S. K. & Hankins, G. D. V., Jan 2013, In : NeoReviews. 14, 1

Research output: Contribution to journalArticle

2 Scopus citations

Nifedipine pharmacokinetics are influenced by CYP3A5 genotype when used as a preterm labor tocolytic

Haas, D. M., Quinney, S. K., Clay, J. M., Renbarger, J. L., Hebert, M. F., Clark, S., Umans, J. G. & Caritis, S. N., Jan 1 2013, In : American Journal of Perinatology. 30, 4, p. 275-282 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Tacrolimus placental transfer at delivery and neonatal exposure through breast milk

Zheng, S., Easterling, T. R., Hays, K., Umans, J. G., Miodovnik, M., Clark, S., Calamia, J. C., Thummel, K. E., Shen, D. D., Davis, C. L. & Hebert, M. F., Dec 1 2013, In : British Journal of Clinical Pharmacology. 76, 6, p. 988-996 9 p.

Research output: Contribution to journalArticle

31 Scopus citations
2012

A semi-mechanistic metabolism model of CYP3A substrates in pregnancy: Predicting changes in midazolam and nifedipine pharmacokinetics

Quinney, S. K., Mohamed, A. N., Hebert, M. F., Haas, D. M., Clark, S., Umans, J. G., Caritis, S. N. & Li, L., Dec 1 2012, In : CPT: Pharmacometrics and Systems Pharmacology. 1, 1, e2.

Research output: Contribution to journalArticle

15 Scopus citations

Determinants of adherence to delayed-release doxylamine and pyridoxine in patients with nausea and vomiting of pregnancy

Costantine, M. M., Matok, I., Chiossi, G., Clark, S., Miodovnik, M., Umans, J. G., Caritis, S., Hankins, G. D. V. & Koren, G., Oct 1 2012, In : Therapeutic Drug Monitoring. 34, 5, p. 569-573 5 p.

Research output: Contribution to journalArticle

3 Scopus citations
2011

Pharmacotherapy and pregnancy: Highlights from the third international conference for individualized pharmacotherapy in pregnancy

Haas, D. M., Gallauresi, B., Shields, K., Zeitlin, D., Clark, S. M., Hebert, M. F., Ren, Z., Nallani, S. C., Meslin, E. M., Feibus, K. B., Koren, G., Goebel, W. S., Easterling, T., Denne, S. C., Flockhart, D. A. & Renbarger, J. L., Jun 1 2011, In : Clinical and translational science. 4, 3, p. 204-209 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

The role of oxidative stress in the developmental origin of adult hypertension

Ghulmiyyah, L. M., Costantine, M. M., Yin, H., Tamayo, E., Clark, S. M., Hankins, G. D. V., Saade, G. R. & Longo, M., Aug 2011, In : American journal of obstetrics and gynecology. 205, 2, p. 155.e7-155.e11

Research output: Contribution to journalArticle

10 Scopus citations
2010

Effectiveness of delayed-release doxylamine and pyridoxine for nausea and vomiting of pregnancy: A randomized placebo controlled trial

Koren, G., Clark, S., Hankins, G. D. V., Caritis, S. N., Miodovnik, M., Umans, J. G. & Mattison, D. R., Dec 2010, In : American journal of obstetrics and gynecology. 203, 6, p. 571.e1-571.e7

Research output: Contribution to journalArticle

60 Scopus citations

Pharmacokinetics of metformin during pregnancy

Eyal, S., Easterling, T. R., Carr, D., Umans, J. G., Miodovnik, M., Hankins, G. D. V., Clark, S. M., Risler, L., Wang, J., Kelly, E. J., Shen, D. D. & Hebert, M. F., May 1 2010, In : Drug Metabolism and Disposition. 38, 5, p. 833-840 8 p.

Research output: Contribution to journalArticle

96 Scopus citations
2009

Pharmacotherapy and pregnancy: Highlights from the second international conference for individualized pharmacotherapy in pregnancy

Haas, D. M., Hebert, M. F., Soldin, O. P., Flockhart, D. A., Madadi, P., Nocon, J. J., Chambers, C. D., Hankins, G. D., Clark, S., Wisner, K. L., Li, L., Renbarger, J. L. & Learman, L. A., Dec 1 2009, In : Clinical and translational science. 2, 6, p. 439-443 5 p.

Research output: Contribution to journalArticle

15 Scopus citations
2008

Antenatal antecedents and the impact of obstetric care in the etiology of cerebral palsy

Clark, S. M., Ghulmiyyah, L. M. & Hankins, G. D. V., Dec 1 2008, In : Clinical Obstetrics and Gynecology. 51, 4, p. 775-786 12 p.

Research output: Contribution to journalArticle

38 Scopus citations
2007

Amniotic fluid embolism: An obstetrical enigma

Clark, S., Maynard, S. L. & Hankins, G., Sep 1 2007, In : Expert Review of Obstetrics and Gynecology. 2, 5, p. 641-650 10 p.

Research output: Contribution to journalArticle

Effect of a previous pregnancy on vascular function in endothelial nitric oxide synthase 3 knockout mice

Ghulmiyyah, L. M., Tamayo, E., Clark, S. M., Hankins, G. D. V., Anderson, G. D., Saade, G. R. & Longo, M., Sep 2007, In : American journal of obstetrics and gynecology. 197, 3, p. 279.e1-279.e5

Research output: Contribution to journalArticle

4 Scopus citations

The effect of the postnatal environment on altered fetal programming of adult vascular function in mice that lack endothelial nitric oxide synthase

Clark, S. M., Makhlouf, M., Hankins, G. D. V., Anderson, G. D., Saade, G. R. & Longo, M., Apr 2007, In : American journal of obstetrics and gynecology. 196, 4, p. 354.e1-354.e7

Research output: Contribution to journalArticle

6 Scopus citations
1999

Maternal oxygen transport variables during the third trimester of normal pregnancy

Hankins, G. D. V., Clark, S. L., Uckan, E. & Van Hook, J. W., Jan 1 1999, In : American journal of obstetrics and gynecology. 180, 2 I, p. 406-409 4 p.

Research output: Contribution to journalArticle

10 Scopus citations