Shinji Makino, DVM, PhD

  • 6197 Citations
  • 46 h-Index
1981 …2020

Research output per year

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Research Output

  • 6197 Citations
  • 46 h-Index
  • 139 Article
  • 7 Review article
  • 3 Chapter
  • 1 Editorial
2009

Differential virological and immunological outcome of severe acute respiratory syndrome coronavirus infection in susceptible and resistant transgenic mice expressing human angiotensin-converting enzyme 2

Yoshikawa, N., Yoshikawa, T., Hill, T., Huang, C., Watts, D. M., Makino, S., Milligan, G., Chan, T., Peters, C. J. & Tseng, C. T. K., Jun 2009, In : Journal of virology. 83, 11, p. 5451-5465 15 p.

Research output: Contribution to journalArticle

14 Scopus citations

Dual functions of rift valley fever virus NSs protein: Inhibition of host mRNA transcription and post-transcriptional downregulation of protein kinase PKR

Ikegami, T., Narayanan, K., Won, S., Kamitani, W., Peters, C. J. & Makino, S., Sep 2009, In : Annals of the New York Academy of Sciences. 1171, SUPPL. 1, p. E75-E85

Research output: Contribution to journalReview article

55 Scopus citations

Rift Valley fever vaccines

Ikegami, T. & Makino, S., Nov 5 2009, In : Vaccine. 27, SUPPL. 4, p. D69-D72

Research output: Contribution to journalArticle

94 Scopus citations

Rift valley fever virus L protein forms a biologically active oligomer

Zamoto-Niikura, A., Terasaki, K., Ikegami, T., Peters, C. J. & Makino, S., Dec 2009, In : Journal of virology. 83, 24, p. 12779-12789 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Rift Valley fever virus NSs protein promotes post-transcriptional downregulation of protein kinase PKR and inhibits eIF2α phosphorylation

Ikegami, T., Narayanan, K., Won, S., Kamitani, W., Peters, C. J. & Makino, S., Feb 2009, In : PLoS pathogens. 5, 2, e1000287.

Research output: Contribution to journalArticle

153 Scopus citations

Suppression of host gene expression by nsp1 proteins of group 2 bat coronaviruses

Tohya, Y., Narayanan, K., Kamitani, W., Huang, C., Lokugamage, K. & Makino, S., May 2009, In : Journal of virology. 83, 10, p. 5282-5288 7 p.

Research output: Contribution to journalArticle

29 Scopus citations
2010

Rapid accumulation of virulent rift valley fever virus in mice from an attenuated virus carrying a single nucleotide substitution in the M RNA

Morrill, J. C., Ikegami, T., Yoshikawa-Iwata, N., Lokugamage, N., Won, S., Terasaki, K., Zamoto-Niikura, A., Peters, C. J. & Makino, S., Sep 10 2010, In : PloS one. 5, 4, e9986.

Research output: Contribution to journalArticle

30 Scopus citations
2011

Alphacoronavirus transmissible gastroenteritis virus nsp1 protein suppresses protein translation in mammalian cells and in cell-free HeLa cell extracts but not in rabbit reticulocyte lysate

Huang, C., Lokugamage, K. G., Rozovics, J. M., Narayanan, K., Semler, B. L. & Makino, S., Jan 1 2011, In : Journal of virology. 85, 1, p. 638-643 6 p.

Research output: Contribution to journalArticle

34 Scopus citations

A structural analysis of M protein in coronavirus assembly and morphology

Neuman, B. W., Kiss, G., Kunding, A. H., Bhella, D., Baksh, M. F., Connelly, S., Droese, B., Klaus, J. P., Makino, S., Sawicki, S. G., Siddell, S. G., Stamou, D. G., Wilson, I. A., Kuhn, P. & Buchmeier, M. J., Apr 2011, In : Journal of Structural Biology. 174, 1, p. 11-22 12 p.

Research output: Contribution to journalArticle

89 Scopus citations

Cyclosporin A inhibits the replication of diverse coronaviruses

de Wilde, A. H., Zevenhoven-Dobbe, J. C., van der Meer, Y., Thiel, V., Narayanan, K., Makino, S., Snijder, E. J. & van Hemert, M. J., Nov 2011, In : Journal of General Virology. 92, 11, p. 2542-2548 7 p.

Research output: Contribution to journalArticle

88 Scopus citations

Mechanism of tripartite RNA genome packaging in Rift Valley fever virus

Terasaki, K., Murakami, S., Lokugamage, K. G. & Makino, S., Jan 11 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 2, p. 804-809 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

Rift Valley Fever

Peters, C. J., Makino, S. & Morrill, J. C., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 462-465 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: Viral mRNAs are resistant to nsp1-induced RNA cleavage

Huang, C., Lokugamage, K. G., Rozovics, J. M., Narayanan, K., Semler, B. L. & Makino, S., Dec 2011, In : PLoS pathogens. 7, 12, e1002433.

Research output: Contribution to journalArticle

83 Scopus citations

The pathogenesis of rift valley fever

Ikegami, T. & Makino, S., May 2011, In : Viruses. 3, 5, p. 493-519 27 p.

Research output: Contribution to journalReview article

157 Scopus citations
2012

Roles of the coding and noncoding regions of rift valley fever virus RNA genome segments in viral RNA packaging

Murakami, S., Terasaki, K., Narayanan, K. & Makino, S., Apr 2012, In : Journal of virology. 86, 7, p. 4034-4039 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Severe acute respiratory syndrome coronavirus protein nsp1 is a novel eukaryotic translation inhibitor that represses multiple steps of translation initiation

Lokugamage, K. G., Narayanan, K., Huang, C. & Makino, S., Dec 2012, In : Journal of virology. 86, 24, p. 13598-13608 11 p.

Research output: Contribution to journalArticle

29 Scopus citations
5 Scopus citations
2013

Characterization of Synthetic Chikungunya Viruses Based on the Consensus Sequence of Recent E1-226V Isolates

Scholte, F. E. M., Tas, A., Martina, B. E. E., Cordioli, P., Narayanan, K., Makino, S., Snijder, E. J. & van Hemert, M. J., Aug 1 2013, In : PloS one. 8, 8, e71047.

Research output: Contribution to journalArticle

41 Scopus citations

Immunogenicity of a recombinant Rift Valley fever MP-12-NSm deletion vaccine candidate in calves

Morrill, J. C., Laughlin, R. C., Lokugamage, N., Wu, J., Pugh, R., Kanani, P., Adams, L. G., Makino, S. & Peters, C. J., Oct 9 2013, In : Vaccine. 31, 43, p. 4988-4994 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Interplay between viruses and host mRNA degradation

Narayanan, K. & Makino, S., Jun 2013, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1829, 6-7, p. 732-741 10 p.

Research output: Contribution to journalReview article

25 Scopus citations

Safety and immunogenicity of recombinant Rift Valley fever MP-12 vaccine candidates in sheep

Morrill, J. C., Laughlin, R. C., Lokugamage, N., Pugh, R., Sbrana, E., Weise, W. J., Adams, L. G., Makino, S. & Peters, C. J., Jan 7 2013, In : Vaccine. 31, 3, p. 559-565 7 p.

Research output: Contribution to journalArticle

37 Scopus citations
34 Scopus citations

The Nucleocapsid Protein of Rift Valley Fever Virus Is a Potent Human CD8+ T Cell Antigen and Elicits Memory Responses

Xu, W., Watts, D. M., Costanzo, M. C., Tang, X., Venegas, L. A., Jiao, F., Sette, A., Sidney, J., Sewell, A. K., Wooldridge, L., Makino, S., Morrill, J. C., Peters, C. J. & Kan-Mitchell, J., Mar 18 2013, In : PloS one. 8, 3, e59210.

Research output: Contribution to journalArticle

18 Scopus citations
2014

Development of a Novel, Single-Cycle Replicable Rift Valley Fever Vaccine

Murakami, S., Terasaki, K., Ramirez, S. I., Morrill, J. C. & Makino, S., Mar 2014, In : PLoS neglected tropical diseases. 8, 3, e2746.

Research output: Contribution to journalArticle

11 Scopus citations
2015

Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression

Narayanan, K., Ramirez, S. I., Lokugamage, K. G. & Makino, S., Apr 16 2015, In : Virus Research. 202, p. 89-100 12 p.

Research output: Contribution to journalArticle

37 Scopus citations

Interplay between the Virus and Host in Rift Valley Fever Pathogenesis

Terasaki, K. & Makino, S., Aug 25 2015, In : Journal of Innate Immunity. 7, p. 450-458 9 p.

Research output: Contribution to journalReview article

12 Scopus citations

Middle east respiratory syndrome coronavirus nsp1 inhibits host gene expression by selectively targeting mRNAs transcribed in the nucleus while sparing mRNAs of cytoplasmic origin

Lokugamage, K. G., Narayanan, K., Nakagawa, K., Terasaki, K., Ramirez, S. I., Tseng, C. T. K. & Makino, S., 2015, In : Journal of virology. 89, 21, p. 10970-10981 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Single-cycle replicable Rift Valley fever virus mutants as safe vaccine candidates

Terasaki, K., Tercero, B. R. & Makino, S., 2015, (Accepted/In press) In : Virus Research.

Research output: Contribution to journalArticle

6 Scopus citations
2016

Generation of a single-cycle replicable Rift Valley fever vaccine

Murakami, S., Terasaki, K. & Makino, S., Apr 1 2016, Methods in Molecular Biology. Humana Press Inc., Vol. 1403. p. 187-206 20 p. (Methods in Molecular Biology; vol. 1403).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations
3 Scopus citations

Protein Phosphatase-1 regulates Rift Valley fever virus replication

Baer, A., Shafagati, N., Benedict, A., Ammosova, T., Ivanov, A., Hakami, R. M., Terasaki, K., Makino, S., Nekhai, S. & Kehn-Hall, K., Mar 1 2016, In : Antiviral research. 127, p. 79-89 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
8 Scopus citations

Viral and Cellular mRNA Translation in Coronavirus-Infected Cells

Nakagawa, K., Lokugamage, K. G. & Makino, S., Dec 1 2016, Advances in Virus Research. Academic Press Inc., p. 165-192 28 p. (Advances in Virus Research; vol. 96).

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access
18 Scopus citations
2018

A new comprehensive method for detection of livestock-related pathogenic viruses using a target enrichment system

Oba, M., Tsuchiaka, S., Omatsu, T., Katayama, Y., Otomaru, K., Hirata, T., Aoki, H., Murata, Y., Makino, S., Nagai, M. & Mizutani, T., Jan 8 2018, In : Biochemical and Biophysical Research Communications. 495, 2, p. 1871-1877 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

A single-cycle replicable Rift Valley fever phlebovirus vaccine carrying a mutated NSs confers full protection from lethal challenge in mice

Terasaki, K., Juelich, T. L., Smith, J. K., Kalveram, B., Perez, D. D., Freiberg, A. N. & Makino, S., Dec 1 2018, In : Scientific reports. 8, 1, 17097.

Research output: Contribution to journalArticle

2 Scopus citations

Dembo polymerase chain reaction technique for detection of bovine abortion, diarrhea, and respiratory disease complex infectious agents in potential vectors and reservoirs

Rahpaya, S. S., Tsuchiaka, S., Kishimoto, M., Oba, M., Katayama, Y., Nunomura, Y., Kokawa, S., Kimura, T., Kobayashi, A., Kirino, Y., Okabayashi, T., Nonaka, N., Mekata, H., Aoki, H., Shiokawa, M., Umetsu, M., Morita, T., Hasebe, A., Otsu, K., Asai, T. & 6 others, Yamaguchi, T., Makino, S., Murata, Y., Abi, A. J., Omatsu, T. & Mizutani, T., 2018, In : Journal of Veterinary Science. 19, 3, p. 350-357 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Discovery of genome of an immunodeficiency-associated virus-like virus from pig feces in Japan

Oba, M., Katayama, Y., Tsuchiaka, S., Omatsu, T., Murata, Y., Ohya, K., Makino, S., Nagai, M. & Mizutani, T., 2018, In : Japanese Journal of Veterinary Research. 66, 1, p. 53-56 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Genetic diversity and recombination of enterovirus G strains in Japanese pigs: High prevalence of strains carrying a papain-like cysteine protease sequence in the enterovirus G population

Tsuchiaka, S., Naoi, Y., Imai, R., Masuda, T., Ito, M., Akagami, M., Ouchi, Y., Ishii, K., Sakaguchi, S., Omatsu, T., Katayama, Y., Oba, M., Shirai, J., Satani, Y., Takashima, Y., Taniguchi, Y., Takasu, M., Madarame, H., Sunaga, F., Aoki, H. & 3 others, Makino, S., Mizutani, T. & Nagai, M., Jan 2018, In : PloS one. 13, 1, e0190819.

Research output: Contribution to journalArticle

10 Scopus citations
16 Scopus citations

Interplay between coronavirus, a cytoplasmic RNA virus, and nonsense-mediated mRNA decay pathway

Wada, M., Lokugamage, K. G., Nakagawa, K., Narayanan, K. & Makino, S., Oct 23 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. E10157-E10166

Research output: Contribution to journalArticle

10 Scopus citations

Introduction to Virology special issue featuring nidovirus research

Fang, Y., Baker, S., Snijder, E., Gallagher, T., Makino, S. & Nauwynck, H., Apr 2018, In : Virology. 517, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Metagenomic identification and sequence analysis of a Teschovirus A-related virus in porcine feces in Japan, 2014–2016

Oba, M., Naoi, Y., Ito, M., Masuda, T., Katayama, Y., Sakaguchi, S., Omatsu, T., Furuya, T., Yamasato, H., Sunaga, F., Makino, S., Mizutani, T. & Nagai, M., Dec 2018, In : Infection, Genetics and Evolution. 66, p. 210-216 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

The endonucleolytic RNA cleavage function of nsp1 of middle east respiratory syndrome coronavirus promotes the production of infectious virus particles in specific human cell lines

Nakagawa, K., Narayanan, K., Wada, M., Popov, V. L., Cajimat, M., Baric, R. S. & Makino, S., Nov 1 2018, In : Journal of virology. 92, 21, e01157.

Research output: Contribution to journalArticle

6 Scopus citations

Whole genome analysis of a novel picornavirus related to the Enterovirus/Sapelovirus supergroup from porcine feces in Japan

Masuda, T., Sunaga, F., Naoi, Y., Ito, M., Takagi, H., Katayama, Y., Omatsu, T., Oba, M., Sakaguchi, S., Furuya, T., Yamasato, H., Shirai, J., Makino, S., Mizutani, T. & Nagai, M., Sep 15 2018, In : Virus Research. 257, p. 68-73 6 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

A novel defective recombinant porcine enterovirus G virus carrying a porcine torovirus papain-like cysteine protease gene and a putative anti-apoptosis gene in place of viral structural protein genes

Imai, R., Nagai, M., Oba, M., Sakaguchi, S., Ujike, M., Kimura, R., Kida, M., Masuda, T., Kuroda, M., Wen, R., Li, K., Katayama, Y., Naoi, Y., Tsuchiaka, S., Omatsu, T., Yamazato, H., Makino, S. & Mizutani, T., Nov 2019, In : Infection, Genetics and Evolution. 75, 103975.

Research output: Contribution to journalArticle

1 Scopus citations

A strand-specific real-time quantitative RT-PCR assay for distinguishing the genomic and antigenomic RNAs of Rift Valley fever phlebovirus

Tercero, B., Terasaki, K., Nakagawa, K., Narayanan, K. & Makino, S., Oct 1 2019, In : Journal of Virological Methods. 272, 113701.

Research output: Contribution to journalArticle

1 Scopus citations
2020

An Infectious cDNA Clone of SARS-CoV-2

Xie, X., Muruato, A., Lokugamage, K. G., Narayanan, K., Zhang, X., Zou, J., Liu, J., Schindewolf, C., Bopp, N. E., Aguilar, P. V., Plante, K. S., Weaver, S. C., Makino, S., LeDuc, J. W., Menachery, V. D. & Shi, P. Y., May 13 2020, In : Cell Host and Microbe. 27, 5, p. 841-848.e3

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Molecular characterization of feline paramyxovirus in Japanese cat populations

Sakaguchi, S., Nakagawa, S., Mitsuhashi, S., Ogawa, M., Sugiyama, K., Tamukai, K., Koide, R., Katayama, Y., Nakano, T., Makino, S., Imanishi, T., Miyazawa, T. & Mizutani, T., Feb 1 2020, In : Archives of virology. 165, 2, p. 413-418 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Reverse genetics approaches for the development of bunyavirus vaccines

Tercero, B. & Makino, S., Oct 2020, In : Current Opinion in Virology. 44, p. 16-25 10 p.

Research output: Contribution to journalReview article

Severe acute respiratory syndrome coronavirus 2 from patient with coronavirus disease, United States

Harcourt, J., Tamin, A., Lu, X., Kamili, S., Sakthivel, S. K., Murray, J., Queen, K., Tao, Y., Paden, C. R., Zhang, J., Li, Y., Uehara, A., Wang, H., Goldsmith, C., Bullock, H. A., Wang, L., Whitaker, B., Lynch, B., Gautam, R., Schindewolf, C. & 14 others, Lokugamage, K. G., Scharton, D., Plante, J. A., Mirchandani, D., Widen, S. G., Narayanan, K., Makino, S., Ksiazek, T. G., Plante, K. S., Weaver, S. C., Lindstrom, S., Tong, S., Menachery, V. D. & Thornburg, N. J., Jun 1 2020, In : Emerging infectious diseases. 26, 6, p. 1266-1273 8 p.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations