Stanley Watowich, PhD

  • 2272 Citations
  • 27 h-Index
1985 …2021
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  • 3 Similar Profiles
Venezuelan Equine Encephalitis Viruses Medicine & Life Sciences
Viruses Chemical Compounds
Nicotinamide N-Methyltransferase Medicine & Life Sciences
Alphavirus Medicine & Life Sciences
Nucleocapsid Medicine & Life Sciences
Dengue Virus Medicine & Life Sciences
Proteins Medicine & Life Sciences
Aldehyde Reductase Medicine & Life Sciences

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Projects 2012 2021

Research Output 1985 2019

  • 2272 Citations
  • 27 h-Index
  • 59 Article
  • 2 Conference contribution

Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle

Neelakantan, H., Brightwell, C. R., Graber, T., Maroto, R., Wang, H. Y. L., McHardy, S. F., Papaconstantinou, J., Fry, C. & Watowich, S., Jan 1 2019, In : Biochemical Pharmacology.

Research output: Contribution to journalArticle

Nicotinamide N-Methyltransferase
Stem cells
Muscle Cells
Muscle
Skeletal Muscle
6 Citations (Scopus)

Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice

Neelakantan, H., Vance, V., Wetzel, M. D., Wang, H. Y. L., McHardy, S. F., Finnerty, C., Hommel, J. & Watowich, S., Jan 1 2018, In : Biochemical Pharmacology. 147, p. 141-152 12 p.

Research output: Contribution to journalArticle

Nicotinamide N-Methyltransferase
High Fat Diet
Nutrition
Obesity
Fats
5 Citations (Scopus)

Host oxidative folding pathways offer novel anti-chikungunya virus drug targets with broad spectrum potential

Langsjoen, R., Auguste, A. J., Rossi, S., Roundy, C. M., Penate, H. N., Kastis, M., Schnizlein, M. K., Le, K. C., Haller, S. L., Chen, R., Watowich, S. & Weaver, S., Jul 1 2017, In : Antiviral Research. 143, p. 246-251 6 p.

Research output: Contribution to journalArticle

Chikungunya virus
Protein Disulfide-Isomerases
Auranofin
Alphavirus
Pharmaceutical Preparations
10 Citations (Scopus)

Noncoupled Fluorescent Assay for Direct Real-Time Monitoring of Nicotinamide N-Methyltransferase Activity

Neelakantan, H., Vance, V., Wang, H. Y. L., McHardy, S. F. & Watowich, S., Feb 14 2017, In : Biochemistry. 56, 6, p. 824-832 9 p.

Research output: Contribution to journalArticle

Nicotinamide N-Methyltransferase
Assays
Monitoring
Substrates
Methionine
11 Citations (Scopus)

Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase

Neelakantan, H., Wang, H. Y., Vance, V., Hommel, J., McHardy, S. F. & Watowich, S., Jun 22 2017, In : Journal of Medicinal Chemistry. 60, 12, p. 5015-5028 14 p.

Research output: Contribution to journalArticle

Nicotinamide N-Methyltransferase
Structure-Activity Relationship
Inhibitory Concentration 50
Binding Sites
Ligands