• 666 Citations
  • 14 h-Index
20112019
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Research Output 2011 2019

  • 666 Citations
  • 14 h-Index
  • 21 Article
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Article
2019
2 Citations (Scopus)

Interleukin-33 Promotes REG3γ Expression in Intestinal Epithelial Cells and Regulates Gut Microbiota

Xiao, Y., Huang, X., Zhao, Y., Chen, F., Sun, M., Yang, W., Chen, L., Yao, S., Peniche-Trujillo, A-G., Dann-Grice, S., Sun, J., Golovko, G., Fofanov, Y., Miao, Y., Liu, Z., Chen, D. & Cong, Y., Jan 1 2019, In : CMGH. 8, 1, p. 21-36 16 p.

Research output: Contribution to journalArticle

Open Access
Epithelial Cells
Citrobacter rodentium
Homeostasis
Gastrointestinal Microbiome
Interleukin-33
4 Citations (Scopus)

Microbiota Metabolite Butyrate Differentially Regulates Th1 and Th17 Cells' Differentiation and Function in Induction of Colitis

Chen, L., Sun, M., Wu, W., Yang, W., Huang, X., Xiao, Y., Ma, C., Xu, L., Yao, S., Liu, Z. & Cong, Y., Aug 20 2019, In : Inflammatory bowel diseases. 25, 9, p. 1450-1461 12 p.

Research output: Contribution to journalArticle

Th17 Cells
Th1 Cells
Butyrates
Microbiota
Colitis
1 Citation (Scopus)

Microbiota metabolite short-chain fatty acids facilitate mucosal adjuvant activity of cholera toxin through GPR43

Yang, W., Xiao, Y., Huang, X., Chen, F., Sun, M., Bilotta, A. J., Xu, L., Lu, Y., Yao, S., Zhao, Q., Liu, Z. & Cong, Y., Jan 1 2019, In : Journal of Immunology. 203, 1, p. 282-292 11 p.

Research output: Contribution to journalArticle

Volatile Fatty Acids
Cholera Toxin
Microbiota
B-Lymphocytes
Citrobacter rodentium
2 Citations (Scopus)

RORγt represses IL-10 production in Th17 cells to maintain their pathogenicity in inducing intestinal inflammation

Sun, M., He, C., Chen, L., Yang, W., Wu, W., Chen, F., Cao, A. T., Yao, S., Dann-Grice, S., Dhar, T. G. M., Salter-Cid, L., Zhao, Q., Liu, Z. & Cong, Y., Jan 1 2019, In : Journal of Immunology. 202, 1, p. 79-92 14 p.

Research output: Contribution to journalArticle

Th17 Cells
Interleukin-10
Virulence
Inflammation
T-Lymphocytes
2018
23 Citations (Scopus)

GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3

Zhao, Y., Chen, F., Wu, W., Sun, M., Bilotta, A. J., Yao, S., Xiao, Y., Huang, X., Eaves-Pyles, T., Golovko, G., Fofanov, Y., D'Souza, W., Zhao, Q., Liu, Z. & Cong, Y., May 1 2018, In : Mucosal Immunology. 11, 3, p. 752-762 11 p.

Research output: Contribution to journalArticle

Volatile Fatty Acids
Microbiota
Defensins
Epithelial Cells
Peptides
25 Citations (Scopus)

Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis

Sun, M., Wu, W., Chen, L., Yang, W., Huang, X., Ma, C., Chen, F., Xiao, Y., Zhao, Y., Ma, C., Yao, S., Carpio, V. H., Dann-Grice, S., Zhao, Q., Liu, Z. & Cong, Y., Dec 1 2018, In : Nature Communications. 9, 1, 3555.

Research output: Contribution to journalArticle

homeostasis
Th1 Cells
Volatile Fatty Acids
Microbiota
fatty acids
3 Citations (Scopus)

Neutrophils promote amphiregulin production in intestinal epithelial cells through TGF-β and contribute to intestinal homeostasis

Chen, F., Yang, W., Huang, X., Cao, A. T., Bilotta, A. J., Xiao, Y., Sun, M., Chen, L., Ma, C., Liu, X., Liu, C. G., Yao, S., Dann-Grice, S., Liu, Z. & Cong, Y., Oct 15 2018, In : Journal of Immunology. 201, 8, p. 2492-2501 10 p.

Research output: Contribution to journalArticle

Neutrophils
Homeostasis
Epithelial Cells
Colitis
Dextran Sulfate
2017
55 Citations (Scopus)

Microbiota metabolite short-chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43

Wu, W., Sun, M., Chen, F., Cao, A. T., Liu, H., Zhao, Y., Huang, X., Xiao, Y., Yao, S., Zhao, Q., Liu, Z. & Cong, Y., Jul 1 2017, In : Mucosal Immunology. 10, 4, p. 946-956 11 p.

Research output: Contribution to journalArticle

Volatile Fatty Acids
Microbiota
Immunoglobulin A
Acetates
Tretinoin
2016
11 Citations (Scopus)

Commensal A4 bacteria inhibit intestinal Th2-cell responses through induction of dendritic cell TGF-β production

Wu, W., Liu, H. P., Chen, F., Liu, H., Cao, A. T., Yao, S., Sun, M., Evans-Marin, H. L., Zhao, Y., Zhao, Q., Duck, L. W., Elson, C. O., Liu, Z. & Cong, Y., 2016, (Accepted/In press) In : European Journal of Immunology.

Research output: Contribution to journalArticle

Th2 Cells
Dendritic Cells
Bacteria
Th17 Cells
Th1 Cells
32 Citations (Scopus)

MTOR mediates IL-23 induction of neutrophil IL-17 and IL-22 production

Chen, F., Cao, A., Yao, S., Evans-Marin, H. L., Liu, H., Wu, W., Carlsen, E. D., Dann-Grice, S., Soong, L., Sun, J., Zhao, Q. & Cong, Y., May 15 2016, In : Journal of Immunology. 196, 10, p. 4390-4399 10 p.

Research output: Contribution to journalArticle

Interleukin-23
Interleukin-17
Neutrophils
Colitis
Microbiota
14 Citations (Scopus)

TLR5 mediates CD172α + intestinal lamina propria dendritic cell induction of Th17 cells

Liu, H., Chen, F., Wu, W., Cao, A. T., Xue, X., Yao, S., Evans-Marin, H. L., Li, Y. Q. & Cong, Y., Feb 24 2016, In : Scientific Reports. 6, 22040.

Research output: Contribution to journalArticle

Th17 Cells
Dendritic Cells
Mucous Membrane
Microbiota
Intestines
2015
22 Citations (Scopus)

Exchange protein directly activated by cAMP modulates regulatory T-cell-mediated immunosuppression

Almahariq, M., Mei, F. C., Wang, H., Cao, A. T., Yao, S., Soong, L., Sun, J., Cong, Y., Chen, J. & Cheng, X., Jan 15 2015, In : Biochemical Journal. 465, p. 295-303 9 p.

Research output: Contribution to journalArticle

T-cells
Regulatory T-Lymphocytes
Immunosuppression
Pharmacology
T-Lymphocytes
47 Citations (Scopus)

Interleukin (IL)-21 promotes intestinal IgA response to microbiota

Cao, A. T., Yao, S., Gong, B., Nurieva, R. I., Elson, C. O. & Cong, Y., Sep 19 2015, In : Mucosal Immunology. 8, 5, p. 1072-1082 11 p.

Research output: Contribution to journalArticle

Microbiota
Immunoglobulin A
B-Lymphocytes
Immunoglobulin Isotypes
Genetic Recombination
57 Citations (Scopus)

miR-10a inhibits dendritic cell activation and Th1/Th17 cell immune responses in IBD

Wu, W., He, C., Liu, C., Cao, A. T., Xue, X., Evans-Marin, H. L., Sun, M., Fang, L., Yao, S., Pinchuk, I., Powell, D. W., Liu, Z. & Cong, Y., Nov 1 2015, In : Gut. 64, 11, p. 1755-1764 10 p.

Research output: Contribution to journalArticle

Th17 Cells
Th1 Cells
MicroRNAs
Dendritic Cells
Interleukins
46 Citations (Scopus)

TGF-β converts Th1 cells into Th17 cells through stimulation of Runx1 expression

Liu, H. P., Cao, A. T., Feng, T., Li, Q., Zhang, W., Yao, S., Dann-Grice, S., Elson, C. O. & Cong, Y., Apr 1 2015, In : European Journal of Immunology. 45, 4, p. 1010-1018 9 p.

Research output: Contribution to journalArticle

Th17 Cells
Th1 Cells
Interleukin-17
Colitis
T-Lymphocytes
12 Citations (Scopus)

Unexpected regulatory role of CCR9 in regulatory T cell development

Evans-Marin, H. L., Cao, A. T., Yao, S., Chen, F., He, C., Liu, H., Wu, W., Gonzalez, M. G., Dann-Grice, S. & Cong, Y., Jul 31 2015, In : PLoS One. 10, 7, e0134100.

Research output: Contribution to journalArticle

T-cells
Regulatory T-Lymphocytes
T-lymphocytes
T-Lymphocytes
inflammatory bowel disease
2014
34 Citations (Scopus)

Downregulation of microRNA-107 in intestinal CD11c+ myeloid cells in response to microbiota and proinflammatory cytokines increases IL-23p19 expression

Xue, X., Cao, A. T., Cao, X., Yao, S., Carlsen, E. D., Soong, L., Liu, C. G., Liu, X., Liu, Z., Duck, L. W., Elson, C. O. & Cong, Y., 2014, In : European Journal of Immunology. 44, 3, p. 673-682 10 p.

Research output: Contribution to journalArticle

Interleukin-23 Subunit p19
Microbiota
Myeloid Cells
MicroRNAs
Down-Regulation
28 Citations (Scopus)

Tlr4 regulates IFN-γ and IL-17 production by both thymic and induced Foxp3+Tregsduring intestinal inflammation

Cao, A. T., Yao, S., Stefka, A. T., Liu, Z., Qin, H., Liu, H., Evans-Marin, H. L., Elson, C. O., Nagler, C. R. & Cong, Y., Nov 1 2014, In : Journal of Leukocyte Biology. 96, 5, p. 895-905 11 p.

Research output: Contribution to journalArticle

Interleukin-17
Intestines
Inflammation
Cytokines
Interleukin-10
2013
44 Citations (Scopus)

ERK differentially regulates Th17- and Treg-cell development and contributes to the pathogenesis of colitis

Liu, H., Yao, S., Dann-Grice, S., Qin, H., Elson, C. O. & Cong, Y., Jul 2013, In : European Journal of Immunology. 43, 7, p. 1716-1726 11 p.

Research output: Contribution to journalArticle

Th17 Cells
Regulatory T-Lymphocytes
Colitis
T-Lymphocytes
MAP Kinase Signaling System
2012
117 Citations (Scopus)

Th17 cells upregulate polymeric Ig receptor and intestinal IgA and contribute to intestinal homeostasis

Cao, A. T., Yao, S., Gong, B., Elson, C. O. & Cong, Y., Nov 1 2012, In : Journal of Immunology. 189, 9, p. 4666-4673 8 p.

Research output: Contribution to journalArticle

Polymeric Immunoglobulin Receptors
Th17 Cells
Immunoglobulin A
Homeostasis
Up-Regulation
2011
87 Citations (Scopus)

Microbiota downregulates dendritic cell expression of miR-10a, which targets IL-12/IL-23p40

Xue, X., Feng, T., Yao, S., Wolf, K. J., Liu, C. G., Liu, X., Elson, C. O. & Cong, Y., Dec 1 2011, In : Journal of Immunology. 187, 11, p. 5879-5886 8 p.

Research output: Contribution to journalArticle

Microbiota
Interleukin-12
Dendritic Cells
Down-Regulation
MicroRNAs