Thomas Geisbert, PhD, MS

  • 16198 Citations
  • 70 h-Index
1989 …2024

Research output per year

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Research Output

1989

Comparison of in vivo and in vitro toxic effects of microcystin-LR in fasted rats

Miura, G. A., Robinson, N. A., Geisbert, T. W., Bostian, K. A., White, J. D. & Pace, J. G., 1989, In : Toxicon. 27, 11, p. 1229-1240 12 p.

Research output: Contribution to journalArticle

76 Scopus citations
1990

Preliminary report: isolation of Ebola virus from monkeys imported to USA

Jahrling, P. B., Geisbert, T. W., Johnson, E. D., Peters, C. J., Dalgard, D. W. & Hall, W. C., Mar 3 1990, In : The Lancet. 335, 8688, p. 502-505 4 p.

Research output: Contribution to journalArticle

277 Scopus citations

Use of immunoelectron microscopy to show Ebola virus during the 1989 United States epizootic

Geisbert, T. W. & Jahrling, P. B., Jan 1 1990, In : Journal of Clinical Pathology. 43, 10, p. 813-816 4 p.

Research output: Contribution to journalArticle

40 Scopus citations
1991

Rapid identification of Ebola virus and related filoviruses in fluid specimens using indirect immunoelectron microscopy

Geisbert, T. W., Rhoderick, J. B. & Jahrling, P. B., Jan 1 1991, In : Journal of Clinical Pathology. 44, 6, p. 521-522 2 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Toxicity and kinetics of [3H]microcystin-LR in isolated perfused rat livers

Pace, J. G., Robinson, N. A., Miura, G. A., Matson, C. F., Geisbert, T. W. & White, J. D., Mar 1 1991, In : Toxicology and Applied Pharmacology. 107, 3, p. 391-401 11 p.

Research output: Contribution to journalArticle

28 Scopus citations
1992

Association of Ebola-related Reston virus particles and antigen with tissue lesions of monkeys imported to the United States

Geisbert, T. W., Jahrling, P. B., Hanes, M. A. & Zack, P. M., Feb 1992, In : Journal of comparative pathology. 106, 2, p. 137-152 16 p.

Research output: Contribution to journalArticle

117 Scopus citations
1993

Use of immunoelectron microscopy to demonstrate Francisella tularensis

Geisbert, T. W., Jahrling, P. B. & Ezzell, J. W., Jan 1 1993, In : Journal of Clinical Microbiology. 31, 7, p. 1936-1939 4 p.

Research output: Contribution to journalComment/debate

7 Scopus citations
1994

Virologic investigation of a case of suspected haemorrhagic fever

Kenyon, R. H., Niklasson, B., Jahrling, P. B., Geisbert, T., Svensson, L., Frydén, A., Bengtsson, M., Foberg, U. & Peters, C. J., 1994, In : Research in Virology. 145, C, p. 397-406 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
1995

Differentiation of filoviruses by electron microscopy

Geisbert, T. W. & Jahrling, P. B., Dec 1995, In : Virus Research. 39, 2-3, p. 129-150 22 p.

Research output: Contribution to journalArticle

187 Scopus citations

Transmission of Ebola virus (Zaire strain) to uninfected control monkeys in a biocontainment laboratory

Jaax, N., Jahrling, P., Geisbert, T., Geisbert, J., Steele, K., McKee, K., Nagley, D., Johnson, E., Jaax, G. & Peters, C., Dec 30 1995, In : The Lancet. 346, 8991-8892, p. 1669-1671 3 p.

Research output: Contribution to journalArticle

134 Scopus citations
1996

Characterization of a new Marburg virus isolated from a 1987 fatal case in Kenya

Johnson, E. D., Johnson, B. K., Silverstein, D., Tukei, P., Geisbert, T. W., Sanchez, A. N. & Jahrling, P. B., Dec 1 1996, In : Archives of Virology, Supplement. 1996, 11, p. 101-114 14 p.

Research output: Contribution to journalArticle

125 Scopus citations

Characterization of Oliveros virus, a new member of the Tacaribe complex (Arenaviridae: Arenavirus)

Mills, J. N., Barrera Oro, J. G., Bressler, D. S., Childs, J. E., Tesh, R. B., Smith, J. F., Enria, D. A., Geisbert, T. W., McKee, K. T., Bowen, M. D., Peters, C. J. & Jahrling, P. B., Apr 1996, In : American Journal of Tropical Medicine and Hygiene. 54, 4, p. 399-404 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Experimental infection of cynomolgus macaques with Ebola-Reston filoviruses from the 1989-1990 U.S. epizootic

Jahrling, P. B., Geisbert, T. W., Jaax, N. K., Hanes, M. A., Ksiazek, T. G. & Peters, C. J., Dec 1 1996, In : Archives of Virology, Supplement. 1996, 11, p. 115-134 20 p.

Research output: Contribution to journalArticle

87 Scopus citations

Experimental infection of guinea pigs with Venezuelan hemorrhagic fever virus (Guanarito): A model of human disease

Hall, W. C., Geisbert, T. W., Huggins, J. W. & Jahrling, P. B., Jul 1996, In : American Journal of Tropical Medicine and Hygiene. 55, 1, p. 81-88 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Lethal experimental infection of rhesus monkeys with Ebola-Zaire (Mayinga) virus by the oral and conjunctival route of exposure

Jaax, N. K., Davis, K. J., Geisbert, T. J., Vogel, P., Jaax, G. P., Topper, M. & Jahrling, P. B., Feb 1 1996, In : Archives of Pathology and Laboratory Medicine. 120, 2, p. 140-155 16 p.

Research output: Contribution to journalArticle

179 Scopus citations
1997

Pathology of experimental Ebola virus infection in African green monkeys: Involvement of fibroblastic reticular cells

Davis, K. J., Anderson, A. O., Geisbert, T. W., Steele, K. E., Geisbert, J. B., Vogel, P., Connolly, B. M., Huggins, J. W., Jahrling, P. B. & Jaax, N. K., Sep 6 1997, In : Archives of Pathology and Laboratory Medicine. 121, 8, p. 805-819 15 p.

Research output: Contribution to journalArticle

107 Scopus citations

Pulmonary Lesions in Experimental Ophidian Paramyxovirus Pneumonia of Aruba Island Rattlesnakes, Crotalus unicolor

Jacobson, E. R., Adams, H. P., Geisbert, T. W., Tucker, S. J., Hall, B. J. & Homer, B. L., Sep 1997, In : Veterinary Pathology. 34, 5, p. 450-459 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

The agents of biological warfare

Vogel, P., Fritz, D. L., Kuehl, K., Davis, K. J. & Geisbert, T., Aug 19 1997, In : Journal of the American Medical Association. 278, 5, p. 438-439 2 p.

Research output: Contribution to journalArticle

8 Scopus citations
1998

A mouse model for evaluation of prophylaxis and therapy of ebola hemorrhagic fever

Bray, M., Davis, K., Geisbert, T., Schmaljohn, C. & Huggins, J., Jan 1 1998, In : Journal of Infectious Diseases. 178, 3, p. 651-661 11 p.

Research output: Contribution to journalArticle

Open Access
296 Scopus citations

Erratum: A mouse model for evaluation of prophylaxis and therapy of Ebola hemorrhagic fever (Journal of Infectious Diseases (September 1998) 178 (651-661))

Bray, M., Davis, K., Geisbert, T., Schmaljohn, C. & Huggins, J., Jan 1 1998, In : Journal of Infectious Diseases. 178, 5, 1 p.

Research output: Contribution to journalComment/debate

Marburg hemorrhagic fever: Report of a case studied by immunohistochemistry and electron microscopy

Geisbert, T. W. & Jaax, N. K., Jan 1 1998, In : Ultrastructural Pathology. 22, 1, p. 3-17 15 p.

Research output: Contribution to journalArticle

61 Scopus citations
1999

A mouse model for evaluation of prophylaxis and therapy of Ebola hemorrhagic fever

Bray, M., Davis, K., Geisbert, T., Schmaljohn, C. & Huggins, J., Mar 1 1999, In : Journal of Infectious Diseases. 179, SUPPL. 1, p. S248-S258

Research output: Contribution to journalArticle

123 Scopus citations

Ebola (subtype Reston) virus among quarantined nonhuman primates recently imported from the Philippines to the United States

Rollin, P. E., Williams, R. J., Bressler, D. S., Pearson, S., Cottingham, M., Pucak, G., Sanchez, A., Trappier, S. G., Peters, R. L., Greer, P. W., Zaki, S., Demarcus, T., Hendricks, K., Kelley, M., Simpson, D., Geisbert, T. W., Jahrling, P. B., Peters, C. J. & Ksiazek, T. G., Mar 1 1999, In : Journal of Infectious Diseases. 179, SUPPL. 1, p. S108-S114

Research output: Contribution to journalArticle

111 Scopus citations

Evaluation of immune globulin and recombinant interferon-α2b for treatment of experimental Ebola virus infections

Jahrling, P. B., Geisbert, T. W., Geisbert, J. B., Swearengen, J. R., Bray, M., Jaax, N. K., Huggins, J. W., LeDuc, J. W. & Peters, C. J., Mar 1 1999, In : Journal of Infectious Diseases. 179, SUPPL. 1, p. S224-S234

Research output: Contribution to journalArticle

224 Scopus citations

Pathogenesis of experimental Ebola virus infection in guinea pigs

Connolly, B. M., Steele, K. E., Davis, K. J., Geisbert, T. W., Kell, W. M., Jaax, N. K. & Jahrling, P. B., Mar 1 1999, In : Journal of Infectious Diseases. 179, SUPPL. 1, p. S203-S217

Research output: Contribution to journalArticle

240 Scopus citations
2000

Apoptosis induced in vitro and in vivo during infection by Ebola and Marburg viruses

Geisbert, T. W., Hensley, L. E., Gibb, T. R., Steele, K. E., Jaax, N. K. & Jahrling, P. B., Feb 2000, In : Laboratory Investigation. 80, 2, p. 171-186 16 p.

Research output: Contribution to journalArticle

Open Access
234 Scopus citations

Pathology of fatal west nile virus infections in native and exotic birds during the 1999 outbreak in New York City, New York

Steele, K. E., Linn, M. J., Schoepp, R. J., Komar, N., Geisbert, T. W., Manduca, R. M., Calle, P. P., Raphael, B. L., Clippinger, T. L., Larsen, T., Smith, J., Lanciotti, R. S., Panella, N. A. & McNamara, T. S., Jan 1 2000, In : Veterinary Pathology. 37, 3, p. 208-224 17 p.

Research output: Contribution to journalArticle

Open Access
340 Scopus citations
2001

Pathogenesis of experimental Ebola Zaire virus infection in BALB/c mice

Gibb, T. R., Bray, M., Geisbert, T. W., Steele, K. E., Kell, W. M., Davis, K. J. & Jaax, N. K., Jan 1 2001, In : Journal of Comparative Pathology. 125, 4, p. 233-242 10 p.

Research output: Contribution to journalArticle

104 Scopus citations

The pathology of experimental aerosolized monkeypox virus infection in cynomolgus monkeys (Macaca fascicularis)

Zaucha, G. M., Jahrling, P. B., Geisbert, T. W., Swearengen, J. R. & Hensley, L., Jan 1 2001, In : Laboratory Investigation. 81, 12, p. 1581-1600 20 p.

Research output: Contribution to journalArticle

Open Access
131 Scopus citations
2002

3-Deazaneplanocin A induces massively increased interferon-α production in Ebola virus-infected mice

Bray, M., Raymond, J. L., Geisbert, T. & Baker, R. O., Jun 29 2002, In : Antiviral research. 55, 1, p. 151-159 9 p.

Research output: Contribution to journalArticle

94 Scopus citations

Detection of antibodies against the four subtypes of ebola virus in Sera from any species using a novel antibody-phage indicator assay

Meissner, F., Maruyama, T., Frentsch, M., Hessell, A. J., Rodriguez, L. L., Geisbert, T. W., Jahrling, P. B., Burton, D. R. & Parren, P. W. H. I., Jan 1 2002, In : Virology. 300, 2, p. 236-243 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Evaluation in nonhuman primates of vaccines against Ebola virus

Geisbert, T. W., Pushko, P., Anderson, K., Smith, J., Davis, K. J. & Jahrling, P. B., Jan 1 2002, In : Emerging infectious diseases. 8, 5, p. 503-507 5 p.

Research output: Contribution to journalReview article

Open Access
196 Scopus citations

Evidence against an important role for infectivity-enhancing antibodies in Ebola virus infections

Geisbert, T. W., Hensley, L. E., Geisbert, J. B. & Jahrling, P. B., Jan 1 2002, In : Virology. 293, 1, p. 15-19 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Human T-lymphotropic virus type 1 oncoprotein tax promotes S-phase entry but blocks mitosis

Liang, M. H., Geisbert, T., Yao, Y., Hinrichs, S. H. & Giam, C. Z., Apr 6 2002, In : Journal of virology. 76, 8, p. 4022-4033 12 p.

Research output: Contribution to journalArticle

63 Scopus citations

Lipid raft microdomains: A gateway for compartmentalized trafficking of Ebola and Marburg viruses

Bavari, S., Bosio, C. M., Wiegand, E., Ruthel, G., Will, A. B., Geisbert, T. W., Hevey, M., Schmaljohn, C., Schmaljohn, A. & Javad Aman, M., Mar 4 2002, In : Journal of Experimental Medicine. 195, 5, p. 593-602 10 p.

Research output: Contribution to journalArticle

358 Scopus citations

Pre- and postexposure prophylaxis of ebola virus infection in an animal model by passive transfer of a neutralizing human antibody

Parren, P. W. H. I., Geisbert, T. W., Maruyama, T., Jahrling, P. B. & Burton, D. R., Jun 5 2002, In : Journal of virology. 76, 12, p. 6408-6412 5 p.

Research output: Contribution to journalArticle

163 Scopus citations

Proinflammatory response during Ebola virus infection of primate models: Possible involvement of the tumor necrosis factor receptor superfamily

Hensley, L. E., Young, H. A., Jahrling, P. B. & Geisbert, T. W., Mar 1 2002, In : Immunology Letters. 80, 3, p. 169-179 11 p.

Research output: Contribution to journalArticle

190 Scopus citations
2003

Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates

Sullivan, N. J., Geisbert, T. W., Gelsbert, J. B., Xu, L., Yang, Z. Y., Roederer, M., Koup, R. A., Jahrling, P. B. & Nabel, G. J., Aug 7 2003, In : Nature. 424, 6949, p. 681-684 4 p.

Research output: Contribution to journalArticle

383 Scopus citations

Hantaviruses induce cytopathic effects and apoptosis in continuous human embryonic kidney cells

Markotic, A., Hensley, L., Geisbert, T., Spik, K. & Schmaljohn, C., Aug 1 2003, In : Journal of General Virology. 84, 8, p. 2197-2202 6 p.

Research output: Contribution to journalShort survey

40 Scopus citations

Mechanisms Underlying Coagulation Abnormalities in Ebola Hemorrhagic Fever: Overexpression of Tissue Factor in Primate Monocytes/Macrophages Is a Key Event

Geisbert, T. W., Young, H. A., Jahrling, P. B., Davis, K. J., Kagan, E. & Hensley, L. E., Dec 1 2003, In : Journal of Infectious Diseases. 188, 11, p. 1618-1629 12 p.

Research output: Contribution to journalArticle

273 Scopus citations

Pathogenesis of Ebola Hemorrhagic Fever in Cynomolgus Macaques: Evidence that Dendritic Cells are Early and Sustained Targets of Infection

Geisbert, T. W., Hensley, L. E., Larsen, T., Young, H. A., Reed, D. S., Geisbert, J. B., Scott, D. P., Kagan, E., Jahrling, P. B. & Davis, K. J., Dec 2003, In : American Journal of Pathology. 163, 6, p. 2347-2370 24 p.

Research output: Contribution to journalArticle

408 Scopus citations

Pathogenesis of Ebola Hemorrhagic Fever in Primate Models: Evidence that Hemorrhage Is Not a Direct Effect of Virus-Induced Cytolysis of Endothelial Cells

Geisbert, T. W., Young, H. A., Jahrling, P. B., Davis, K. J., Larsen, T., Kagan, E. & Hensley, L. E., Dec 2003, In : American Journal of Pathology. 163, 6, p. 2371-2382 12 p.

Research output: Contribution to journalArticle

239 Scopus citations

Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus

Yount, B., Curtis, K. M., Fritz, E. A., Hensley, L. E., Jahrling, P. B., Prentice, E., Denison, M. R., Geisbert, T. W. & Baric, R. S., Oct 28 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 22, p. 12995-13000 6 p.

Research output: Contribution to journalArticle

213 Scopus citations

Towards a vaccine against Ebola virus

Geisbert, T. W. & Jahrling, P. B., Dec 1 2003, In : Expert review of vaccines. 2, 6, p. 777-789 13 p.

Research output: Contribution to journalReview article

41 Scopus citations

Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: A study in rhesus monkeys

Geisbert, T. W., Hensley, L. E., Jahrling, P. B., Larsen, T., Geisbert, J. B., Paragas, J., Young, H. A., Fredeking, T. M., Rote, W. E. & Vlasuk, G. P., Dec 13 2003, In : Lancet. 362, 9400, p. 1953-1958 6 p.

Research output: Contribution to journalArticle

293 Scopus citations
2004

Depletion of peripheral blood T lymphocytes and NK cells during the course of Ebola hemorrhagic fever in cynomolgus macaques

Reed, D. S., Hensley, L. E., Geisbert, J. B., Jahrling, P. B. & Geisbert, T. W., Sep 29 2004, In : Viral Immunology. 17, 3, p. 390-400 11 p.

Research output: Contribution to journalArticle

119 Scopus citations

Detection and identification of Variola virus in fixed human tissue after prolonged archival storage

Schoepp, R. J., Morin, M. D., Martinez, M. J., Kulesh, D. A., Hensley, L., Geisbert, T., Brady, D. R. & Jahrling, P. B., Jan 1 2004, In : Laboratory Investigation. 84, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Detection and identification of Variola virus in fixed human tissue after prolonged archival storage

Schoepp, R. J., Morin, M. D., Martinez, M. J., Kulesh, D. A., Hensley, L., Geisbert, T. W., Brady, D. R. & Jahrling, P. B., 2004, In : Laboratory Investigation. 84, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

Ebola virus: New insights into disease aetiopathology and possible therapeutic interventions

Geisbert, T. W. & Hensley, L. E., Sep 1 2004, In : Expert reviews in molecular medicine. 6, 20

Research output: Contribution to journalReview article

74 Scopus citations

Exotic emerging viral diseases: Progress and challenges

Geisbert, T. W. & Jahrling, P. B., Dec 2004, In : Nature Medicine. 10, 12S, p. S110-S121

Research output: Contribution to journalReview article

349 Scopus citations