Thomas Geisbert, PhD, MS

  • 16529 Citations
  • 70 h-Index
1989 …2020

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2020

A Cross-Reactive Humanized Monoclonal Antibody Targeting Fusion Glycoprotein Function Protects Ferrets Against Lethal Nipah Virus and Hendra Virus Infection

Mire, C. E., Chan, Y. P., Borisevich, V., Cross, R. W., Yan, L., Agans, K. N., Dang, H. V., Veesler, D., Fenton, K. A., Geisbert, T. W. & Broder, C. C., May 11 2020, In : Journal of Infectious Diseases. 221, p. S471-S479

Research output: Contribution to journalArticle

Open Access

A Lethal Aerosol Exposure Model of Nipah Virus Strain Bangladesh in African Green Monkeys

Prasad, A. N., Agans, K. N., Sivasubramani, S. K., Geisbert, J. B., Borisevich, V., Mire, C. E., Lawrence, W. S., Fenton, K. A. & Geisbert, T. W., May 11 2020, In : Journal of Infectious Diseases. 221, p. S431-S435

Research output: Contribution to journalArticle

1 Scopus citations

Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization

Gilchuk, P., Murin, C. D., Milligan, J. C., Cross, R. W., Mire, C. E., Ilinykh, P. A., Huang, K., Kuzmina, N., Altman, P. X., Hui, S., Gunn, B. M., Bryan, A. L., Davidson, E., Doranz, B. J., Turner, H. L., Alkutkar, T., Flinko, R., Orlandi, C., Carnahan, R., Nargi, R. & 13 others, Bombardi, R. G., Vodzak, M. E., Li, S., Okoli, A., Ibeawuchi, M., Ohiaeri, B., Lewis, G. K., Alter, G., Bukreyev, A., Saphire, E. O., Geisbert, T. W., Ward, A. B. & Crowe, J. E., Feb 18 2020, In : Immunity. 52, 2, p. 388-403.e12

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

An Intranasal Exposure Model of Lethal Nipah Virus Infection in African Green Monkeys

Geisbert, J. B., Borisevich, V., Prasad, A. N., Agans, K. N., Foster, S. L., Deer, D. J., Cross, R. W., Mire, C. E., Geisbert, T. W. & Fenton, K. A., May 11 2020, In : Journal of Infectious Diseases. 221, p. S414-S418

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Early transcriptional changes within liver, adrenal gland, and lymphoid tissues significantly contribute to Ebola virus pathogenesis in cynomolgus macaques

Jankeel, A., Menicucci, A. R., Woolsey, C., Fenton, K., Mendoza, N., Versteeg, K., Cross, R. W., Geisbert, T. W. & Messaoudi, I., Jun 1 2020, In : Journal of virology. 94, 11, e00250-20.

Research output: Contribution to journalArticle

Immune correlates of postexposure vaccine protection against Marburg virus

Woolsey, C., Jankeel, A., Matassov, D., Geisbert, J. B., Agans, K. N., Borisevich, V., Cross, R. W., Deer, D. J., Fenton, K. A., Latham, T. E., Gerardi, C. S., Mire, C. E., Eldridge, J. H., Messaoudi, I. & Geisbert, T. W., Dec 1 2020, In : Scientific reports. 10, 1, 3071.

Research output: Contribution to journalArticle

Open Access

Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death

Cross, R. W., Xu, R., Matassov, D., Hamm, S., Latham, T. E., Gerardi, C. S., Nowak, R. M., Geisbert, J. B., Ota-Setlik, A., Agans, K. N., Luckay, A., Witko, S. E., Soukieh, L., Deer, D. J., Mire, C. E., Feldmann, H., Happi, C., Fenton, K., Eldridge, J. H. & Geisbert, T. W., Jan 2 2020, In : Journal of Clinical Investigation. 130, 1, p. 539-551 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Rational design of universal immunotherapy for TfR1-tropic arenaviruses

Cohen-Dvashi, H., Amon, R., Agans, K. N., Cross, R. W., Borenstein-Katz, A., Mateo, M., Baize, S., Padler-Karavani, V., Geisbert, T. W. & Diskin, R., Dec 1 2020, In : Nature communications. 11, 1, 67.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Resistance of Cynomolgus Monkeys to Nipah and Hendra Virus Disease Is Associated with Cell-Mediated and Humoral Immunity

Prasad, A. N., Woolsey, C., Geisbert, J. B., Agans, K. N., Borisevich, V., Deer, D. J., Mire, C. E., Cross, R. W., Fenton, K. A., Broder, C. C. & Geisbert, T. W., May 11 2020, In : Journal of Infectious Diseases. 221, p. S436-S447

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Structure and Characterization of Crimean-Congo Hemorrhagic Fever Virus GP38

Mishra, A. K., Moyer, C. L., Abelson, D. M., Deer, D. J., El Omari, K., Duman, R., Lobel, L., Lutwama, J. J., Dye, J. M., Wagner, A., Chandran, K., Cross, R. W., Geisbert, T. W., Zeitlin, L., Bornholdt, Z. A. & McLellan, J. S., Mar 31 2020, In : Journal of virology. 94, 8

Research output: Contribution to journalArticle

Open Access
2019

An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections

Dang, H. V., Chan, Y. P., Park, Y. J., Snijder, J., Da Silva, S. C., Vu, B., Yan, L., Feng, Y. R., Rockx, B., Geisbert, T. W., Mire, C. E., Broder, C. C. & Veesler, D., Oct 1 2019, In : Nature Structural and Molecular Biology. 26, 10, p. 980-987 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Antagonism of STAT1 by Nipah virus P gene products modulates disease course but not lethal outcome in the ferret model

Satterfield, B. A., Borisevich, V., Foster, S. L., Rodriguez, S. E., Cross, R. W., Fenton, K., Agans, K. N., Basler, C. F., Geisbert, T. W. & Mire, C. E., Dec 1 2019, In : Scientific reports. 9, 1, 16710.

Research output: Contribution to journalArticle

Open Access

A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates

Bornholdt, Z. A., Herbert, A. S., Mire, C. E., He, S., Cross, R. W., Wec, A. Z., Abelson, D. M., Geisbert, J. B., James, R. M., Rahim, M. N., Zhu, W., Borisevich, V., Banadyga, L., Gunn, B. M., Agans, K. N., Wirchnianski, A. S., Goodwin, E., Tierney, K., Shestowsky, W. S., Bohorov, O. & 13 others, Bohorova, N., Velasco, J., Ailor, E., Kim, D., Pauly, M. H., Whaley, K. J., Alter, G., Walker, L. M., Chandran, K., Zeitlin, L., Qiu, X., Geisbert, T. W. & Dye, J. M., Jan 9 2019, In : Cell Host and Microbe. 25, 1, p. 49-58.e5

Research output: Contribution to journalArticle

18 Scopus citations

A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge

Woolsey, C., Menicucci, A. R., Cross, R., Luthra, P., Agans, K. N., Borisevich, V., Geisbert, J. B., Mire, C., Fenton, K. A., Jankeel, A., Anand, S., Ebihara, H., Geisbert, T., Messaoudi, I. & Basler, C. F., Sep 17 2019, In : Cell Reports. 28, 12, p. 3032-3046.e6

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Convergent Structures Illuminate Features for Germline Antibody Binding and Pan-Lassa Virus Neutralization

Hastie, K. M., Cross, R. W., Harkins, S. S., Zandonatti, M. A., Koval, A. P., Heinrich, M. L., Rowland, M. M., Robinson, J. E., Geisbert, T. W., Garry, R. F., Branco, L. M. & Saphire, E. O., Aug 8 2019, In : Cell. 178, 4, p. 1004-1015.e14

Research output: Contribution to journalArticle

1 Scopus citations

The FDA-Approved Oral Drug Nitazoxanide Amplifies Host Antiviral Responses and Inhibits Ebola Virus

Jasenosky, L. D., Cadena, C., Mire, C. E., Borisevich, V., Haridas, V., Ranjbar, S., Nambu, A., Bavari, S., Soloveva, V., Sadukhan, S., Cassell, G. H., Geisbert, T. W., Hur, S. & Goldfeld, A. E., Sep 27 2019, In : iScience. 19, p. 1279-1290 12 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Use of Single-Injection Recombinant Vesicular Stomatitis Virus Vaccine to Protect Nonhuman Primates Against Lethal Nipah Virus Disease

Mire, C., Geisbert, J. B., Agans, K. N., Versteeg, K. M., Deer, D. J., Satterfield, B. A., Fenton, K. A. & Geisbert, T., Jun 1 2019, In : Emerging infectious diseases. 25, 6, p. 1144-1152 9 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Vesicular Stomatitis Virus-Based Vaccine Protects Mice against Crimean-Congo Hemorrhagic Fever

Rodriguez, S. E., Cross, R. W., Fenton, K. A., Bente, D. A., Mire, C. E. & Geisbert, T. W., Dec 1 2019, In : Scientific reports. 9, 1, 7755.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2018

A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates

Callendret, B., Vellinga, J., Wunderlich, K., Rodriguez, A., Steigerwald, R., Dirmeier, U., Cheminay, C., Volkmann, A., Brasel, T., Carrion, R., Giavedoni, L. D., Patterson, J. L., Mire, C. E., Geisbert, T. W., Hooper, J. W., Weijtens, M., Hartkoorn-Pasma, J., Custers, J., Pau, M. G., Schuitemaker, H. & 1 others, Zahn, R., Feb 2018, In : PloS one. 13, 2, e0192312.

Research output: Contribution to journalArticle

16 Scopus citations

Comparative Transcriptomics in Ebola Makona-Infected Ferrets, Nonhuman Primates, and Humans

Cross, R., Speranza, E., Borisevich, V., Widen, S., Wood, T., Shim, R. S., Adams, R. D., Gerhardt, D. M., Bennett, R. S., Honko, A. N., Johnson, J. C., Hensley, L. E., Geisbert, T. & Connor, J. H., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S486-S495

Research output: Contribution to journalArticle

8 Scopus citations

Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates

Gilchuk, P., Mire, C., Geisbert, J. B., Agans, K. N., Deer, D. J., Cross, R., Slaughter, J. C., Flyak, A. I., Mani, J., Pauly, M. H., Velasco, J., Whaley, K. J., Zeitlin, L., Geisbert, T. & Crowe, J. E., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S565-S573

Research output: Contribution to journalArticle

1 Scopus citations

Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever

Boisen, M. L., Hartnett, J. N., Shaffer, J. G., Goba, A., Momoh, M., Sandi, J. D., Fullah, M., Nelson, D. K. S., Bush, D. J., Rowland, M. M., Heinrich, M. L., Koval, A. P., Cross, R., Barnes, K. G., Lachenauer, A. E., Lin, A. E., Nekoui, M., Kotliar, D., Winnicki, S. M., Siddle, K. J. & 18 others, Gbakie, M., Fonnie, M., Koroma, V. J., Kanneh, L., Kulakosky, P. C., Hastie, K. M., Wilson, R. B., Andersen, K. G., Folarin, O. O., Happi, C. T., Sabeti, P. C., Geisbert, T., Saphire, E. O., Khan, S. H., Grant, D. S., Schieffelin, J. S., Branco, L. M. & Garry, R. F., Dec 1 2018, In : Scientific Reports. 8, 1, 5939.

Research output: Contribution to journalArticle

9 Scopus citations

Marburg and Ravn Viruses Fail to Cause Disease in the Domestic Ferret (Mustela putorius furo)

Cross, R., Mire, C., Agans, K. N., Borisevich, V., Fenton, K. A. & Geisbert, T., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S448-S452

Research output: Contribution to journalArticle

6 Scopus citations

Postexposure Efficacy of Recombinant Vesicular Stomatitis Virus Vectors Against High and Low Doses of Marburg Virus Variant Angola in Nonhuman Primates

Woolsey, C., Geisbert, J. B., Matassov, D., Agans, K. N., Borisevich, V., Cross, R., Deer, D. J., Fenton, K. A., Eldridge, J. H., Mire, C. & Geisbert, T., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S582-S587

Research output: Contribution to journalArticle

5 Scopus citations

Predicting outcome and improving treatment for Lassa fever

Geisbert, T., Jan 1 2018, (Accepted/In press) In : The Lancet Infectious Diseases.

Research output: Contribution to journalArticle

5 Scopus citations

Role of Antibodies in Protection Against Ebola Virus in Nonhuman Primates Immunized With Three Vaccine Platforms

Warfield, K. L., Howell, K. A., Vu, H., Geisbert, J., Wong, G., Shulenin, S., Sproule, S., Holtsberg, F. W., Leung, D. W., Amarasinghe, G. K., Swenson, D. L., Bavari, S., Kobinger, G. P., Geisbert, T. & Aman, M. J., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S553-S564

Research output: Contribution to journalArticle

8 Scopus citations

Single-dose trivalent VesiculoVax vaccine protects macaques from lethal Ebolavirus and Marburgvirus challenge

Matassov, D., Mire, C. E., Latham, T., Geisbert, J. B., Xu, R., Ota-Setlik, A., Agans, K. N., Kobs, D. J., Wendling, M. Q. S., Burnaugh, A., Rudge, T. L., Sabourin, C. L., Egan, M. A., Clarke, D. K., Geisbert, T. W. & Eldridge, J. H., Feb 1 2018, In : Journal of virology. 92, 3, e01190-17.

Research output: Contribution to journalArticle

12 Scopus citations
2017

Assessment of the potential for host-targeted iminosugars UV-4 and UV-5 activity against filovirus infections in vitro and in vivo

Warfield, K. L., Warren, T. K., Qiu, X., Wells, J., Mire, C. E., Geisbert, J. B., Stuthman, K. S., Garza, N. L., Van Tongeren, S. A., Shurtleff, A. C., Agans, K. N., Wong, G., Callahan, M. V., Geisbert, T. W., Klose, B., Ramstedt, U. & Treston, A. M., Feb 1 2017, In : Antiviral research. 138, p. 22-31 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Disposable cartridge platform for rapid detection of viral hemorrhagic fever viruses

Scherr, S. M., Freedman, D. S., Agans, K. N., Rosca, A., Carter, E., Kuroda, M., Fawcett, H. E., Mire, C. E., Geisbert, T. W., Ünlü, M. S. & Connor, J. H., Mar 7 2017, In : Lab on a Chip. 17, 5, p. 917-925 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Enhanced light microscopy visualization of virus particles from Zika virus to filamentous ebolaviruses

Daaboul, G. G., Freedman, D. S., Scherr, S. M., Carter, E., Rosca, A., Bernstein, D., Mire, C. E., Agans, K. N., Hoenen, T., Geisbert, T. W., Selim Ünlü, M. & Connor, J. H., Jun 2017, In : PloS one. 12, 6, e0179728.

Research output: Contribution to journalArticle

5 Scopus citations

Human-monoclonal-antibody therapy protects nonhuman primates against advanced Lassa fever

Mire, C. E., Cross, R. W., Geisbert, J. B., Borisevich, V., Agans, K. N., Deer, D. J., Heinrich, M. L., Rowland, M. M., Goba, A., Momoh, M., Boisen, M. L., Grant, D. S., Fullah, M., Khan, S. H., Fenton, K. A., Robinson, J. E., Branco, L. M., Garry, R. F. & Geisbert, T. W., Oct 1 2017, In : Nature Medicine. 23, 10, p. 1146-1149 4 p.

Research output: Contribution to journalArticle

35 Scopus citations

Infection with the Makona variant results in a delayed and distinct host immune response compared to previous Ebola virus variants

Versteeg, K., Menicucci, A. R., Woolsey, C., Mire, C., Geisbert, J. B., Cross, R., Agans, K. N., Jeske, D., Messaoudi, I. & Geisbert, T., Dec 1 2017, In : Scientific Reports. 7, 1, 9730.

Research output: Contribution to journalArticle

13 Scopus citations

siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease

Thi, E. P., Mire, C., Lee, A. C. H., Geisbert, J. B., Ursic-Bedoya, R., Agans, K. N., Robbins, M., Deer, D. J., Cross, R., Kondratowicz, A. S., Fenton, K. A., MacLachlan, I. & Geisbert, T., Dec 1 2017, In : Journal of Clinical Investigation. 127, 12, p. 4437-4448 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Therapeutic treatment of marburg and ravn virus infection in nonhuman primates with a human monoclonal antibody

Mire, C. E., Geisbert, J. B., Borisevich, V., Fenton, K. A., Agans, K. N., Flyak, A. I., Deer, D. J., Steinkellner, H., Bohorov, O., Bohorova, N., Goodman, C., Hiatt, A., Kim, D. H., Pauly, M. H., Velasco, J., Whaley, K. J., Crowe, J. E., Zeitlin, L. & Geisbert, T. W., Apr 5 2017, In : Science Translational Medicine. 9, 384, eaai8711.

Research output: Contribution to journalArticle

27 Scopus citations

Transcriptome analysis of circulating immune cell subsets highlight the role of monocytes in Zaire Ebola Virus Makona pathogenesis

Menicucci, A. R., Versteeg, K., Woolsey, C., Mire, C., Geisbert, J. B., Cross, R., Agans, K. N., Jankeel, A., Geisbert, T. & Messaoudi, I., Oct 4 2017, In : Frontiers in Immunology. 8, OCT, 1372.

Research output: Contribution to journalArticle

16 Scopus citations
2016

Analytical Validation of the ReEBOV Antigen Rapid Test for Point-of-Care Diagnosis of Ebola Virus Infection

Cross, R. W., Boisen, M. L., Millett, M. M., Nelson, DI. S., Oottamasathien, D., Hartnett, J. N., Jones, A. B., Goba, A., Momoh, M., Fullah, M., Bornholdt, Z. A., Fusco, M. L., Abelson, D. M., Oda, S., Brown, B. L., Pham, H., Rowland, M. M., Agans, K. N., Geisbert, J. B., Heinrich, M. L. & 14 others, Kulakosky, P. C., Shaffer, J. G., Schieffelin, J. S., Kargbo, B., Gbetuwa, M., Gevao, S. M., Wilson, R. B., Saphire, E. O., Pitts, K. R., Khan, S. H., Grant, D. S., Geisbert, T. W., Branco, L. M. & Garry, R. F., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S210-S217

Research output: Contribution to journalArticle

17 Scopus citations

An Outbreak of Ebola Virus Disease in the Lassa Fever Zone

Goba, A., Khan, S. H., Fonnie, M., Fullah, M., Moigboi, A., Kovoma, A., Sinnah, V., Yoko, N., Rogers, H., Safai, S., Momoh, M., Koroma, V., Kamara, F. K., Konowu, E., Yillah, M., French, I., Mustapha, I., Kanneh, F., Foday, M., McCarthy, H. & 64 others, Kallon, T., Kallon, M., Naiebu, J., Sellu, J., Jalloh, A. A., Gbakie, M., Kanneh, L., Massaly, J. L. B., Kargbo, D., Kargbo, B., Vandi, M., Gbetuwa, M., Gevao, S. M., Sandi, J. D., Jalloh, S. C., Grant, D. S., Blyden, S. O., Crozier, I., Schieffelin, J. S., McLellan, S. L., Jacob, S. T., Boisen, M. L., Hartnett, J. N., Cross, R. W., Branco, L. M., Andersen, K. G., Yozwiak, N. L., Gire, S. K., Tariyal, R., Park, D. J., Haislip, A. M., Bishop, C. M., Melnik, L. I., Gallaher, W. R., Wimley, W. C., He, J., Shaffer, J. G., Sullivan, B. M., Grillo, S., Oman, S., Garry, C. E., Edwards, D. R., McCormick, S. J., Elliott, D. H., Rouelle, J. A., Kannadka, C. B., Reyna, A. A., Bradley, B. T., Yu, H., Yenni, R. E., Hastie, K. M., Geisbert, J. B., Kulakosky, P. C., Wilson, R. B., Oldstone, M. B. A., Pitts, K. R., Henderson, L. A., Robinson, J. E., Geisbert, T. W., Saphire, E. O., Happi, C. T., Asogun, D. A., Sabeti, P. C. & Garry, R. F., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S110-S121

Research output: Contribution to journalArticle

18 Scopus citations

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins

Edwards, M. R., Liu, G., Mire, C. E., Sureshchandra, S., Luthra, P., Yen, B., Shabman, R. S., Leung, D. W., Messaoudi, I., Geisbert, T. W., Amarasinghe, G. K. & Basler, C. F., Feb 23 2016, In : Cell Reports. 14, 7, p. 1632-1640 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Field Validation of the ReEBOV Antigen Rapid Test for Point-of-Care Diagnosis of Ebola Virus Infection

Boisen, M. L., Cross, R. W., Hartnett, J. N., Goba, A., Momoh, M., Fullah, M., Gbakie, M., Safa, S., Fonnie, M., Baimba, F., Koroma, V. J., Geisbert, J. B., McCormick, S., Nelson, DI. K. S., Millett, M. M., Oottamasathien, D., Jones, A. B., Pham, H., Brown, B. L., Shaffer, J. G. & 11 others, Schieffelin, J. S., Kargbo, B., Gbetuwa, M., Gevao, S. M., Wilson, R. B., Pitts, K. R., Geisbert, T. W., Branco, L. M., Khan, S. H., Grant, D. S. & Garry, R. F., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S203-S209

Research output: Contribution to journalArticle

16 Scopus citations

Inhibition of the host antiviral response by Nipah virus: Current understanding and future perspectives

Satterfield, B. A., Geisbert, T. & Mire, C., May 1 2016, In : Future Virology. 11, 5, p. 331-344 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Isolation and characterization of a novel gammaherpesvirus from a microbat cell line

Shabman, R. S., Shrivastava, S., Tsibane, T., Attie, O., Jayaprakash, A., Mire, C. E., Dilley, K. E., Puri, V., Stockwell, T. B., Geisbert, T. W., Sachidanandam, R. & Basler, C. F., Jan 1 2016, In : mSphere. 1, 1, e00070-15.

Research output: Contribution to journalArticle

10 Scopus citations

Molecular Diagnostic Field Test for Point-of-Care Detection of Ebola Virus Directly from Blood

Benzine, J. W., Brown, K. M., Agans, K. N., Godiska, R., Mire, C. E., Gowda, K., Converse, B., Geisbert, T. W., Mead, D. A. & Chander, Y., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S234-S242

Research output: Contribution to journalArticle

14 Scopus citations

Monoclonal antibody therapy for junin virus infection

Zeitlin, L., Geisbert, J. B., Deer, D. J., Fenton, K. A., Bohorov, O., Bohorova, N., Goodman, C., Kim, D., Hiatt, A., Pauly, M. H., Velasco, J., Whaley, K. J., Altmann, F., Gruber, C., Steinkellner, H., Honko, A. N., Kuehne, A. I., Aman, M. J., Sahandi, S., Enterlein, S. & 3 others, Zhan, X., Enria, D. & Geisbert, T. W., Apr 19 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 16, p. 4458-4463 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits

Robinson, J. E., Hastie, K. M., Cross, R. W., Yenni, R. E., Elliott, D. H., Rouelle, J. A., Kannadka, C. B., Smira, A. A., Garry, C. E., Bradley, B. T., Yu, H., Shaffer, J. G., Boisen, M. L., Hartnett, J. N., Zandonatti, M. A., Rowland, M. M., Heinrich, M. L., Martinez-Sobrido, L., Cheng, B., De La Torre, J. C. & 30 others, Andersen, K. G., Goba, A., Momoh, M., Fullah, M., Gbakie, M., Kanneh, L., Koroma, V. J., Fonnie, R., Jalloh, S. C., Kargbo, B., Vandi, M. A., Gbetuwa, M., Ikponmwosa, O., Asogun, D. A., Okokhere, P. O., Follarin, O. A., Schieffelin, J. S., Pitts, K. R., Geisbert, J. B., Kulakoski, P. C., Wilson, R. B., Happi, C. T., Sabeti, P. C., Gevao, S. M., Khan, S. H., Grant, D. S., Geisbert, T. W., Saphire, E. O., Branco, L. M. & Garry, R. F., May 10 2016, In : Nature communications. 7, 11544.

Research output: Contribution to journalArticle

50 Scopus citations

Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets

Satterfield, B. A., Cross, R. W., Fenton, K. A., Borisevich, V., Agans, K. N., Deer, D. J., Graber, J., Basler, C. F., Geisbert, T. W. & Mirea, C. E., 2016, In : Journal of virology. 90, 14, p. 6326-6343 18 p.

Research output: Contribution to journalArticle

12 Scopus citations

Oral and Conjunctival Exposure of Nonhuman Primates to Low Doses of Ebola Makona Virus

Mire, C., Geisbert, J. B., Agans, K. N., Deer, D. J., Fenton, K. A. & Geisbert, T., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S263-S267

Research output: Contribution to journalArticle

14 Scopus citations

Passive Immunotherapy: Assessment of Convalescent Serum Against Ebola Virus Makona Infection in Nonhuman Primates

Mire, C. E., Geisbert, J. B., Agans, K. N., Thi, E. P., Lee, A. C. H., Fenton, K. A. & Geisbert, T. W., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S367-S374

Research output: Contribution to journalArticle

26 Scopus citations

Pathogenic Differences between Nipah Virus Bangladesh and Malaysia Strains in Primates: Implications for Antibody Therapy

Mire, C., Satterfield, B. A., Geisbert, J. B., Agans, K. N., Borisevich, V., Yan, L., Chan, Y. P., Cross, R., Fenton, K. A., Broder, C. C. & Geisbert, T., Aug 3 2016, In : Scientific Reports. 6, 30916.

Research output: Contribution to journalArticle

39 Scopus citations

Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNA

Thi, E. P., Lee, A. C. H., Geisbert, J. B., Ursic-Bedoya, R., Agans, K. N., Robbins, M., Deer, D. J., Fenton, K. A., Kondratowicz, A. S., MacLachlan, I., Geisbert, T. & Mire, C., Aug 22 2016, In : Nature Microbiology. 1, 16142.

Research output: Contribution to journalArticle

18 Scopus citations

Targeting innate immunity for antiviral therapy through small molecule agonists of the RLR pathway

Pattabhi, S., Wilkins, C. R., Dong, R., Knoll, M. L., Posakony, J., Kaiser, S., Mire, C., Wang, M. L., Ireton, R. C., Geisbert, T., Bedard, K. M., Iadonato, S. P., Loo, Y. M. & Gale, M., 2016, In : Journal of Virology. 90, 5, p. 2372-2387 16 p.

Research output: Contribution to journalArticle

25 Scopus citations