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Thomas Smith, PhD

Program Director, Molecular Biophysics Educational Track

  • 6191 Citations
  • 46 h-Index
1982 …2023
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  • 2 Similar Profiles
Glutamate Dehydrogenase Medicine & Life Sciences
Rhinovirus Medicine & Life Sciences
Capsid Medicine & Life Sciences
Viruses Medicine & Life Sciences
Norovirus Medicine & Life Sciences
Cryoelectron Microscopy Medicine & Life Sciences
Allosteric Regulation Medicine & Life Sciences
Antibodies Medicine & Life Sciences

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Projects 2014 2023

Towards new therapeutic treatments for the hyperinsulinism/hyperammonemia

Smith, T.

UNIVERSITY OF PENNSYLVANIA

2/1/20 → 1/31/21

Project: Other project

The Role of Structrual Plasticity in The Norovirus Capsid

Smith, T.

National Inst of Allergy & Infectious Di

2/1/19 → 1/31/23

Project: Other project

High throughput screening for GDH modulators

Smith, T.

AstraZeneca UK Limited

6/1/17 → 5/31/20

Project: Other project

Structure/Function of the Novel Proteins LCIB and LCIC in the Chlamydomonas CCM

Smith, T.

Iowa State University

9/1/14 → 8/14/15

Project: Other project

Research Output 1982 2020

  • 6191 Citations
  • 46 h-Index
  • 125 Article
  • 3 Chapter
  • 1 Comment/debate
  • 1 Review article

Near-atomic-resolution cryo-electron microscopy structures of cucumber leaf spot virus and red clover necrotic mosaic virus: Evolutionary divergence at the icosahedral three-fold axes

Sherman, M. B., Guenther, R., Reade, R., D’Ann, R., Sit, T. & Smitha, T. J., Jan 1 2020, In : Journal of virology. 94, 2, e01439-19.

Research output: Contribution to journal › Article

Cucumber leaf spot virus
Red clover necrotic mosaic virus
Tombusviridae
Cryoelectron Microscopy
Cucumis sativus

Allosteric discrimination at the NADH/ADP regulatory site of glutamate dehydrogenase

Nassar, O. M., Wong, K. Y., Lynch, G. C., Smith, T. J. & Pettitt, B. M., Dec 1 2019, In : Protein Science. 28, 12, p. 2080-2088 9 p.

Research output: Contribution to journal › Article

Glutamate Dehydrogenase
Niacinamide
Diphosphates
Adenine
Hydrides
3 Citations (Scopus)

Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion

Sherman, M., Williams, A. N., Smith, H. Q., Nelson, C., Wilen, C. B., Fremont, D. H., Virgin, H. W. & Smith, T., Oct 1 2019, In : Journal of virology. 93, 19

Research output: Contribution to journal › Article

immune evasion
Immune Evasion
Norovirus
capsid
bile salts

Dissecting the Antenna in Human Glutamate Dehydrogenase: Understanding Its Role in Subunit Communication and Allosteric Regulation

Hoffpauir, Z. A., Sherman, E. & Smith, T. J., Oct 15 2019, In : Biochemistry. 58, 41, p. 4195-4206 12 p.

Research output: Contribution to journal › Article

Allosteric Regulation
Glutamate Dehydrogenase
Communication
Antennas
Purine Nucleotides
3 Citations (Scopus)

The Dynamic Capsid Structures of the Noroviruses

Smith, H. Q. & Smith, T., Mar 8 2019, In : Viruses. 11, 3

Research output: Contribution to journal › Review article

Open Access
Norovirus
Capsid
Herd Immunity
Antibodies
Viral Genome