• 4666 Citations
  • 33 h-Index
20002022

Research output per year

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Research Output

2000

Stem cell factor (SCF) can regulate the activation and expansion of murine intraepithelial lymphocytes

Wang, T., Langley, K. E., Gourley, W. K. & Klimpel, G. R., Mar 2000, In : Cytokine. 12, 3, p. 272-280 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
15 Scopus citations
2001

Immunization of mice against west nile virus with recombinant envelope protein

Wang, T., Anderson, J. F., Magnarelli, L. A., Wong, S. J., Koski, R. A. & Fikrig, E., Nov 1 2001, In : Journal of Immunology. 167, 9, p. 5273-5277 5 p.

Research output: Contribution to journalArticle

Open Access
83 Scopus citations

West Nile virus envelope protein role in diagnosis and immunity

Wang, T., Anderson, J. F., Magnarelli, L. A., Bushmich, S., Wong, S., Koski, R. A. & Fikrig, E., Jan 1 2001, In : Annals of the New York Academy of Sciences. 951, p. 325-327 3 p.

Research output: Contribution to journalArticle

14 Scopus citations
2002

A recombinant envelope protein-based enzyme-linked immunosorbent assay for West Nile virus serodiagnosis.

Wang, T., Magnarelli, L. A., Anderson, J. F., Gould, L. H., Bushmich, S. L., Wong, S. J. & Fikrig, E., Jan 1 2002, In : Vector borne and zoonotic diseases (Larchmont, N.Y.). 2, 2, p. 105-109 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Superoxide anion production during Anaplasma phagocytophila infection

Wang, T., Malawista, S. E., Pal, U., Grey, M., Meek, J., Akkoyunlu, M., Thomas, V. & Fikrig, E., Jul 15 2002, In : Journal of Infectious Diseases. 186, 2, p. 274-280 7 p.

Research output: Contribution to journalArticle

36 Scopus citations
2003

IFN-γ-producing γδ T cells help control murine West Nile virus infection

Wang, T., Scully, E., Yin, Z., Kim, J. H., Wang, S., Yan, J., Mamula, M., Anderson, J. F., Craft, J. & Fikrig, E., Sep 1 2003, In : Journal of Immunology. 171, 5, p. 2524-2531 8 p.

Research output: Contribution to journalArticle

148 Scopus citations

Murine neutrophils require α 1,3-fucosylation but not PSGL-1 for productive infection with Anaplasma phagocytophilum

Carlyon, J. A., Akkoyunlu, M., Xia, L., Yago, T., Wang, T., Cummings, R. D., McEver, R. P. & Fikrig, E., Nov 1 2003, In : Blood. 102, 9, p. 3387-3395 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: A critical role of STAT3 in innate immunity

Welte, T., Zhang, S. S. M., Wang, T., Zhang, Z., Hesslein, D. G. T., Yin, Z., Kano, A., Iwamoto, Y., Li, E., Craft, J. E., Bothwell, A. L. M., Fikrig, E., Koni, P. A., Flavell, R. A. & Fu, X. Y., Feb 18 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 4, p. 1879-1884 6 p.

Research output: Contribution to journalArticle

308 Scopus citations
2004

Detection of Human Anti-Flavivirus Antibodies with a West Nile Virus Recombinant Antigen Microsphere Immunoassay

Wong, S. J., Demarest, V. L., Boyle, R. H., Wang, T., Ledizet, M., Kar, K., Kramer, L. D., Fikrig, E. & Koski, R. A., Jan 1 2004, In : Journal of Clinical Microbiology. 42, 1, p. 65-72 8 p.

Research output: Contribution to journalArticle

95 Scopus citations

Immunity to West Nile virus

Wang, T. & Fikrig, E., Aug 1 2004, In : Current Opinion in Immunology. 16, 4, p. 519-523 5 p.

Research output: Contribution to journalReview article

42 Scopus citations

Interferon-γ deficiency reveals that 129Sv mice are inherently more susceptible to Anaplasma phagocytophilum than C57BL/6 mice

Wang, T., Akkoyunlu, M., Banerjee, R. & Fikrig, E., Nov 1 2004, In : FEMS Immunology and Medical Microbiology. 42, 3, p. 299-305 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Protective niche for Borrelia burgdorferi to evade humoral immunity

Liang, F. T., Brown, E. L., Wang, T., Iozzo, R. V. & Fikrig, E., Sep 2004, In : American Journal of Pathology. 165, 3, p. 977-985 9 p.

Research output: Contribution to journalArticle

89 Scopus citations

Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

Wang, T., Town, T., Alexopoulou, L., Anderson, J. F., Fikrig, E. & Flavell, R. A., Dec 1 2004, In : Nature Medicine. 10, 12, p. 1366-1373 8 p.

Research output: Contribution to journalArticle

793 Scopus citations

TROSPA, an Ixodes scapularis receptor for Borrelia burgdorferi

Pal, U., Li, X., Wang, T., Montgomery, R. R., Ramamoorthi, N., DeSilva, A. M., Bao, F., Yang, X., Pypaert, M., Pradhan, D., Kantor, F. S., Telford, S., Anderson, J. F. & Fikrig, E., Nov 12 2004, In : Cell. 119, 4, p. 457-468 12 p.

Research output: Contribution to journalArticle

257 Scopus citations
2005

A recombinant envelope protein vaccine against West Nile virus

Ledizet, M., Kar, K., Foellmer, H. G., Wang, T., Bushmich, S. L., Anderson, J. F., Fikrig, E. & Koski, R. A., Jun 10 2005, In : Vaccine. 23, 30, p. 3915-3924 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

Protective and herapeutic capacity of human single-chain Fv-Fc fusion proteins against West Nile virus

Gould, L. H., Sui, J., Foellmer, H., Oliphant, T., Wang, T., Ledizet, M., Murakami, A., Noonan, K., Lambeth, C., Kar, K., Anderson, J. F., De Silva, A. M., Diamond, M. S., Koski, R. A., Marasco, W. A. & Fikrig, E., Dec 1 2005, In : Journal of virology. 79, 23, p. 14606-14613 8 p.

Research output: Contribution to journalArticle

100 Scopus citations

Use of RNA interference to prevent lethal murine West Nile virus infection

Bai, F., Wang, T., Pal, U., Bao, F., Gould, L. H. & Fikrig, E., Apr 1 2005, In : Journal of Infectious Diseases. 191, 7, p. 1148-1154 7 p.

Research output: Contribution to journalArticle

80 Scopus citations
2006

CD44 Is the Signaling Component of the Macrophage Migration Inhibitory Factor-CD74 Receptor Complex

Shi, X., Leng, L., Wang, T., Wang, W., Du, X., Li, J., McDonald, C., Chen, Z., Murphy, J. W., Lolis, E., Noble, P., Knudson, W. & Bucala, R., Oct 1 2006, In : Immunity. 25, 4, p. 595-606 12 p.

Research output: Contribution to journalArticle

388 Scopus citations

Gamma interferon plays a crucial early antiviral role in protection against West Nile virus infection

Shrestha, B., Wang, T., Samuel, M. A., Whitby, K., Craft, J., Fikrig, E. & Diamond, M. S., Jun 1 2006, In : Journal of virology. 80, 11, p. 5338-5348 11 p.

Research output: Contribution to journalArticle

135 Scopus citations

γδ T cells facilitate adaptive immunity against West Nile virus infection in mice

Wang, T., Gao, Y., Scully, E., Davis, C. T., Anderson, J. F., Welte, T., Ledizet, M., Koski, R., Madri, J. A., Barrett, A., Yin, Z., Craft, J. & Fikrig, E., Aug 1 2006, In : Journal of Immunology. 177, 3, p. 1825-1832 8 p.

Research output: Contribution to journalArticle

56 Scopus citations
2007

Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion

Arjona, A., Foellmer, H. G., Town, T., Leng, L., McDonald, C., Wang, T., Wong, S. J., Montgomery, R. R., Fikrig, E. & Bucala, R., Oct 1 2007, In : Journal of Clinical Investigation. 117, 10, p. 3059-3066 8 p.

Research output: Contribution to journalArticle

108 Scopus citations
2008

Drak2 contributes to West Nile virus entry into the brain and lethal encephalitis

Wang, S., Welte, T., McGargill, M., Town, T., Thompson, J., Anderson, J. F., Flavell, R. A., Fikrig, E., Hedrick, S. M. & Wang, T., Aug 1 2008, In : Journal of Immunology. 181, 3, p. 2084-2091 8 p.

Research output: Contribution to journalArticle

Open Access
41 Scopus citations

Role of two distinct γδ T cell subsets during West Nile virus infection

Welte, T., Lamb, J., Anderson, J. F., Born, W. K., O'Brien, R. L. & Wang, T., Jul 1 2008, In : FEMS Immunology and Medical Microbiology. 53, 2, p. 275-283 9 p.

Research output: Contribution to journalArticle

33 Scopus citations
2009

Oral administration of active hexose correlated compound enhances host resistance to West Nile encephalitis in mice

Wang, S., Weite, T., Fang, H., Chang, G. J. J., Born, W. K., O'Brien, R. L., Sun, B., Fujii, H., Kosuna, K. I. & Wang, T., Mar 1 2009, In : Journal of Nutrition. 139, 3, p. 598-602 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Toll-like receptor 7-induced immune response to cutaneous West Nile virus infection

Welte, T., Reagan, K., Fang, H., Machain-Williams, C., Zheng, X., Mendell, N., Chang, G. J. J., Wu, P., Blair, C. D. & Wang, T., Nov 9 2009, In : Journal of General Virology. 90, 11, p. 2660-2668 9 p.

Research output: Contribution to journalArticle

68 Scopus citations

Toll-like Receptor 7 Mitigates Lethal West Nile Encephalitis via Interleukin 23-Dependent Immune Cell Infiltration and Homing

Town, T., Bai, F., Wang, T., Kaplan, A. T., Qian, F., Montgomery, R. R., Anderson, J. F., Flavell, R. A. & Fikrig, E., Feb 20 2009, In : Immunity. 30, 2, p. 242-253 12 p.

Research output: Contribution to journalArticle

144 Scopus citations
2010

Role of Hepatitis C virus core protein in viral-induced mitochondrial dysfunction.

Wang, T., Campbell, R. V., Yi, M. K., Lemon, S. M. & Weinman, S. A., Nov 2010, In : Journal of viral hepatitis. 17, 11, p. 784-793 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

γδ T cells promote the maturation of dendritic cells during West Nile virus infection

Fang, H., Welte, T., Zheng, X., Chang, G. J. J., Holbrook, M. R., Soong, L. & Wang, T., Jun 1 2010, In : FEMS Immunology and Medical Microbiology. 59, 1, p. 71-80 10 p.

Research output: Contribution to journalArticle

36 Scopus citations
2011

Human metapneumovirus glycoprotein G inhibits TLR4-dependent signaling in monocyte-derived dendritic cells

Kolli, D., Bao, X., Liu, T., Hong, C., Wang, T., Garofalo, R. P. & Casola, A., Jul 1 2011, In : Journal of Immunology. 187, 1, p. 47-54 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Immune responses to an attenuated West Nile virus NS4B-P38G mutant strain

Welte, T., Xie, G., Wicker, J. A., Whitemanb, M. C., Li, L., Rachamallu, A., Barrett, A. & Wang, T., Jun 24 2011, In : Vaccine. 29, 29-30, p. 4853-4861 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Pivotal Role of Dermal IL-17-Producing γδ T Cells in Skin Inflammation

Cai, Y., Shen, X., Ding, C., Qi, C., Li, K., Li, X., Jala, V. R., Zhang, H. G., Wang, T., Zheng, J. & Yan, J., Oct 28 2011, In : Immunity. 35, 4, p. 596-610 15 p.

Research output: Contribution to journalArticle

506 Scopus citations

Pivotal Role of Dermal IL-17-Producing γδ T Cells in Skin Inflammation

Cai, Y., Shen, X., Ding, C., Qi, C., Li, K., Li, X., Jala, V. R., Zhang, H. G., Wang, T., Zheng, J. & Yan, J., Oct 28 2011, In : Immunity. 35, 4, 1 p.

Research output: Contribution to journalComment/debate

33 Scopus citations

Role of γδ T cells in West Nile virus-induced encephalitis: Friend or foe?

Wang, T., Dec 15 2011, In : Journal of Neuroimmunology. 240-241, p. 22-27 6 p.

Research output: Contribution to journalReview article

8 Scopus citations

Vγ4+ T cells regulate host immune response to West Nile virus infection

Welte, T., Aronson, J., Gong, B., Rachamallu, A., Mendell, N., Tesh, R., Paessler, S., Born, W. K., O'Brien, R. L. & Wang, T., Nov 1 2011, In : FEMS Immunology and Medical Microbiology. 63, 2, p. 183-192 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
2012

A hamster-derived West Nile virus strain is highly attenuated and induces a differential proinflammatory cytokine response in two murine cell lines

Saxena, V., Welte, T., Bao, X., Xie, G., Wang, J., Higgs, S., Tesh, R. B. & Wang, T., Aug 1 2012, In : Virus Research. 167, 2, p. 179-187 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Immunization of Mice with Recombinant Mosquito Salivary Protein D7 Enhances Mortality from Subsequent West Nile Virus Infection via Mosquito Bite

Reagan, K. L., Machain-Williams, C., Wang, T. & Blair, C. D., Dec 1 2012, In : PLoS neglected tropical diseases. 6, 12, e1935.

Research output: Contribution to journalArticle

23 Scopus citations
2013

A Hamster-Derived West Nile Virus Isolate Induces Persistent Renal Infection in Mice

Saxena, V., Xie, G., Li, B., Farris, T., Welte, T., Gong, B., Boor, P., Wu, P., Tang, S. J., Tesh, R. & Wang, T., Jun 2013, In : PLoS neglected tropical diseases. 7, 6, e2275.

Research output: Contribution to journalArticle

22 Scopus citations

A West Nile virus NS4B-P38G mutant strain induces adaptive immunity via TLR7-MyD88-dependent and independent signaling pathways

Xie, G., Welte, T., Wang, J., Whiteman, M. C., Wicker, J. A., Saxena, V., Cong, Y., Barrett, A. D. T. & Wang, T., Aug 28 2013, In : Vaccine. 31, 38, p. 4143-4151 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Early IL-17 production by intrahepatic T cells is important for adaptive immune responses in viral hepatitis

Hou, L., Jie, Z., Desai, M., Liang, Y., Soong, L., Wang, T. & Sun, J., Jan 15 2013, In : Journal of Immunology. 190, 2, p. 621-629 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Immunization with culex tarsalis mosquito salivary gland extract modulates west nile virus infection and disease in mice

Machain-Williams, C., Reagan, K., Wang, T., Zeidner, N. S. & Blair, C. D., Feb 1 2013, In : Viral Immunology. 26, 1, p. 84-92 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

MyD88 controls human metapneumovirus-induced pulmonary immune responses and disease pathogenesis

Ren, J., Kolli, D., Deng, J., Fang, R., Gong, B., Xue, M., Casola, A., Garafalo, R. P., Wang, T. & Bao, X., Sep 1 2013, In : Virus Research. 176, 1-2, p. 241-250 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Role of natural killer and Gamma-delta T cells in West Nile virus infection

Wang, T. & Welte, T., Sep 20 2013, In : Viruses. 5, 9, p. 2298-2310 13 p.

Research output: Contribution to journalReview article

21 Scopus citations
2014

In vitro analysis of MyD88-mediated cellular immune response to West Nile virus mutant strain infection

Xie, G., Whiteman, M. C., Wicker, J. A., Barrett, A. & Wang, T., Nov 27 2014, In : Journal of visualized experiments : JoVE. 93, p. e52121

Research output: Contribution to journalArticle

1 Scopus citations

The co-stimulatory effects of MyD88-dependent toll-like receptor signaling on activation of murine γδ T Cells

Zhang, J., Wang, J., Pang, L., Xie, G., Welte, T., Saxena, V., Wicker, J., Mann, B., Soong, L., Barrett, A., Born, W., O'Brien, R. & Wang, T., Sep 18 2014, In : PloS one. 9, 9, A1350.

Research output: Contribution to journalArticle

12 Scopus citations
2015

A West Nile virus NS4B-P38G mutant strain induces cell intrinsic innate cytokine responses in human monocytic and macrophage cells

Xie, G., Luo, H., Tian, B., Mann, B., Bao, X., McBride, J., Tesh, R., Barrett, A. D. & Wang, T., Feb 11 2015, In : Vaccine. 33, 7, p. 869-878 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
14 Scopus citations

γδ T cells in infection and autoimmunity

Hou, L., Wang, T. & Sun, J., Feb 17 2015, (Accepted/In press) In : International Immunopharmacology.

Research output: Contribution to journalArticle

4 Scopus citations
2016

Dysregulation of toll-like receptor 7 compromises innate and adaptive T cell responses and host resistance to an attenuated West Nile virus infection in old mice

Xie, G., Luo, H., Pang, L., Peng, B., Winkelmann, E., McGruder, B., Hesse, J., Whiteman, M., Campbell, G., Milligan, G., Cong, Y., Barrett, A. & Wang, T., 2016, In : Journal of Virology. 90, 3, p. 1333-1344 12 p.

Research output: Contribution to journalArticle

14 Scopus citations