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William Calhoun, MD

Vice Chair, Research

  • 11153 Citations
  • 53 h-Index
1977 …2021
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Personal profile

Education/Academic qualification

Allergy/Immunology, Fellowship, University of Wisconsin-Madison

… → 1992

Pulmonary, Fellowship, University of Vermont, Burlington

… → 1985

Medicine, Residency, Pennsylvania State University, Hershey

… → 1982

Medicine, MD, Pennsylvania State University, Hershey

… → 1979

Chemistry, BS, University of Delaware

… → 1975

Research interests

  • Asthma

Fingerprint Dive into the research topics where William Calhoun is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Asthma Medicine & Life Sciences
Inflammation Medicine & Life Sciences
Eosinophils Medicine & Life Sciences
Lung Medicine & Life Sciences
Bronchoalveolar Lavage Medicine & Life Sciences
Cytokines Medicine & Life Sciences
Bronchoalveolar Lavage Fluid Medicine & Life Sciences
Alveolar Macrophages Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2009 2021

Study D3250C00059: A Phase 4, Multicenter, Randomized, Double-blind, Parallel Group, Placebo-controlled Study to Evaluate the Effect of Benralizumab on Structural and Lung Function Changes in Severe Eosinophilic Asthmatics (CHINOOK)

Calhoun, W.

AstraZeneca LP

8/19/19 → 8/18/21

Project: Other project

A Long-term, Randomized, Double-blind, Multicenter, Parallel-group, Phase III Study Evaluating the Efficacy and Safety of PT027 Compared to PT007 Administered as Needed in Response to Symptoms in Symptomatic Adults and Children 4 Years of Age or Older

Calhoun, W.

Bond Avillion 2 Development LP

7/22/19 → 7/21/21

Project: Other project

A Phase 2, Randomized, Double-blind, Parallel Group, Placebo Controlled Study to Evaluate the Effect of Tezepelumab on Airway Inflammation in Adults with Inadequately Controlled Asthma on Inhaled Corticosteroids and at least one additional asthma control

Calhoun, W.

AstraZeneca LP

2/6/19 → 2/5/21

Project: Other project

A Multicenter, Open-label, Phase 3b Efficacy and Safety Study of Benralizumab 30 mg Administered Subcutaneously to Reduce Oral Corticosteroid Use in Adult Patients with Severe Eosinophilic Asthma on High-Dose Inhaled Corticosteroid plus Long-acting ?2 Ag

Calhoun, W.

AstraZeneca LP

10/19/18 → 10/18/20

Project: Other project

Protocol #GSK3772847: A randomized, double-blind, parallel group, multicenter, stratified study evaluating the efficacy and safety of repeat doses of GSK3772847 compared with placebo in participants with moderately severe asthma

Calhoun, W.

Parexel International

8/29/18 → 8/28/20

Project: Other project

Research Output 1977 2019

Ethanol Exposure Impairs AMPK Signaling and Phagocytosis in Human Alveolar Macrophages: Role of Ethanol Metabolism

Kaphalia, L., Prathivadibhayankaram, M., Kakumanu, R. D., Kaphalia, B. & Calhoun, W., Jan 1 2019, In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journal › Article

AMP-Activated Protein Kinases
Oxidative stress
Alveolar Macrophages
Phagocytosis
Metabolism

Forced Oscillometry: A New Tool for Assessing Airway Function—Is It Ready for Prime Time?

Ram, J., Pineda-Cely, J. & Calhoun, W., Jan 1 2019, (Accepted/In press) In : Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journal › Editorial

Oscillometry
1 Citation (Scopus)

Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling

Zhao, Y., Tian, B., Sun, H., Zhang, J., Zhang, Y., Ivannikov, M., Motamedi, M., Liu, Z., Zhou, J., Kaphalia, L., Calhoun, W., Maroto, R. & Brasier, A. R., Aug 15 2019, In : Journal of Proteomics. 205, 103415.

Research output: Contribution to journal › Article

Airway Remodeling
Blood Vessels
Homeostasis
Bronchoalveolar Lavage Fluid
Biomarkers

Why do asthma patients cough? New insights into cough in allergic asthma

Puebla-Neira, D. & Calhoun, W., Jan 1 2019, In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journal › Editorial

Cough
Asthma
Inflammation
4 Citations (Scopus)

Mucosal bromodomain-containing protein 4 mediates aeroallergen-induced inflammation and remodeling

Tian, B., Hosoki, K., Liu, Z., Yang, J., Zhao, Y., Sun, H., Zhou, J., Rytting, E., Kaphalia, L., Calhoun, W., Sur, S. & Brasier, A. R., Jan 1 2018, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journal › Article

Dander
Cats
Inflammation
Myofibroblasts
Airway Remodeling