William Calhoun, MD

Personal profile

Education/Academic qualification

Allergy/Immunology, Fellowship, University of Wisconsin-Madison

… → 1992

Pulmonary, Fellowship, University of Vermont, Burlington

… → 1985

Medicine, Residency, Pennsylvania State University, Hershey

… → 1982

Medicine, MD, Pennsylvania State University, Hershey

… → 1979

Chemistry, BS, University of Delaware

… → 1975

Research interests

Asthma

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1 Similar Profiles

Asthma Medicine & Life Sciences

Inflammation Medicine & Life Sciences

Eosinophils Medicine & Life Sciences

Lung Medicine & Life Sciences

Bronchoalveolar Lavage Medicine & Life Sciences

Cytokines Medicine & Life Sciences

Bronchoalveolar Lavage Fluid Medicine & Life Sciences

Antigens Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2009 2021

6 Active
12 Completed

A Phase 2, Randomized, Double-blind, Parallel Group, Placebo Controlled Study to Evaluate the Effect of Tezepelumab on Airway Inflammation in Adults with Inadequately Controlled Asthma on Inhaled Corticosteroids and at least one additional asthma control

Calhoun, W.

2/6/19 → 2/5/21

Project: Other project

A Multicenter, Open-label, Phase 3b Efficacy and Safety Study of Benralizumab 30 mg Administered Subcutaneously to Reduce Oral Corticosteroid Use in Adult Patients with Severe Eosinophilic Asthma on High-Dose Inhaled Corticosteroid plus Long-acting ?2 Ag

Calhoun, W.

10/19/18 → 10/18/20

Project: Other project

Protocol #GSK3772847: A randomized, double-blind, parallel group, multicenter, stratified study evaluating the efficacy and safety of repeat doses of GSK3772847 compared with placebo in participants with moderately severe asthma

Calhoun, W.

8/29/18 → 8/28/20

Project: Other project

Blood Sample Collection in Subjects with Pulmonary Nodules or CT Suspicion of Lung Cancer

Calhoun, W.

4/25/18 → 4/24/20

Project: Other project

A Multicenter, Randomized, Double-blind, Parallel Group, Placebo-controlled, Phase 3b Study to Evaluate the Safety and Efficacy of Benrali21Jmab 30 mg sc in Patients with Sewre Asthma Uncontrolled on Standard of care Treatment

Calhoun, W.

10/12/17 → 10/11/19

Project: Other project

Research Output 1977 2019

10984 Citations
53 h-Index
172 Article
9 Chapter
3 Review article
1 Letter

Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling

Zhao, Y., Tian, B., Sun, H., Zhang, J., Zhang, Y., Ivannikov, M., Motamedi, M., Liu, Z., Zhou, J., Kaphalia, L., Calhoun, W., Maroto, R. & Brasier, A. R., Aug 15 2019, In : Journal of Proteomics. 205, 103415.

Research output: Contribution to journal › Article

Airway Remodeling

Blood Vessels

Homeostasis

Bronchoalveolar Lavage Fluid

Biomarkers

3 Citations (Scopus)

Mucosal bromodomain-containing protein 4 mediates aeroallergen-induced inflammation and remodeling

Tian, B., Hosoki, K., Liu, Z., Yang, J., Zhao, Y., Sun, H., Zhou, J., Rytting, E., Kaphalia, L., Calhoun, W., Sur, S. & Brasier, A. R., Jan 1 2018, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journal › Article

Dander

Cats

Inflammation

Myofibroblasts

Airway Remodeling

7 Citations (Scopus)

Activation of Human Peripheral Blood Eosinophils by Cytokines in a Comparative Time-Course Proteomic/Phosphoproteomic Study

Soman, K. V., Stafford, S. J., Pazdrak, K., Wu, Z., Luo, X., White, W. I., Wiktorowicz, J. E., Calhoun, W. & Kurosky, A., Aug 4 2017, In : Journal of Proteome Research. 16, 8, p. 2663-2679 17 p.

Research output: Contribution to journal › Article

Eosinophils

Proteomics

Blood

Chemical activation

Cytokines

5 Citations (Scopus)